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Asparagus extract shows synergistic effects with exercise for improved heart fitness

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Asparagus extract shows synergistic effects with exercise for improved heart fitness

Researchers in Thailand explored the effects of Asparagus officinalis supplementation alongside HIIT to investigate whether the two could work synergistically.

They reported that the combination “has the potential to improve cardiovascular and respiratory function and serve as a preventive strategy against cardiovascular and respiratory disorders in obese and overweight individuals.”

Botanical extract for cardiovascular health

High-intensity intermittent training (HIIT), which involves short bursts of intense exercise and recovery periods, has been found to improve muscle performance and cardiopulmonary fitness. However, little research has evaluated its impact on cardiovascular and pulmonary function in obese individuals, according to the researchers of the new study.

Ecdysteroids (arthropod steroid hormones) have demonstrated anabolic, fat-reducing, anti-inflammatory and cardioprotective properties, and 20-hydroxyecdysone (20E), which comes from Asparagus officinalis, has been shown to improve physical performance and muscle strength in healthy populations.

Previous studies have found that 20E supplementation reduced body weight, fat, cholesterol and inflammation, and improved muscle strength and bone health in obese individuals. However, the researchers noted that no previous studies have explored the combined effects of HIIT and 20E supplementation on cardiovascular and pulmonary function in obese and overweight individuals.

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Study details

The researchers recruited 72 obese and overweight male and female participants between the ages of 18 and 30 with a BMI over 22.9 kg/m². They were randomized into four groups: the control group, the HIIT group, the AOE (A. officinalis extract) group which received 1.71 mg/kg/day, and the combined HIIT and AOE group. The HIIT Program consisted of three sessions a week, and participants in the AOE and HIIT and AOE groups received capsules and logged their intake twice daily via an app.

The researchers assessed heart rate (HR), HR variability, endothelial function, blood pressure (BP), BP variability, pulmonary function and volume, respiratory muscle strength, chest expansion and body composition at the beginning of the trial and 12 weeks post-intervention.

Results indicated that combining HIIT with 20E supplementation improved heart rate variability, endothelial function andexpiratory muscle strength after 12 weeks, which in turn was found to benefit lung function and exhalation.

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While the 20E group did not experience any significant changes, the researchers suggested that 20E can support molecular pathways related to protein synthesis, inflammation reduction and cardiovascular protection. These effects were more pronounced in the HIIT and AOE group, where the systems activated by the exercise potentially allowed 20E to further improve muscle remodeling, vascular function and autonomic regulation.

The HIIT and AOE groups also showed increased blood flow and enhanced vascular responsiveness, and in comparison to the HIIT group, they showed improved vasodilation, allowing for increased blood flow to tissues. The 20E group did not display significant signs of improved endothelial function.

Resting blood pressure (BP) significantly decreased only in the HIIT group, however, the researchers noted that 20E appeared to reduce BP variability further when combined with HIIT, “suggesting a synergistic effect that may help reduce BP variability”.

“A 12-week HIIT program combined with A. officinalis extract supplementation improved HR variability indices, potentially lowering cardiovascular disease and atherosclerosis risk via increased endothelial function,” the researchers concluded.

“It also enhanced expiratory muscle strength, lower-chest wall expansion and, consequently, pulmonary function. The clinical implication is that utilizing HIIT in conjunction with supplementation with A. officinalis extract containing 20E at 1.71 ± 0.24 mg/kg/day daily for 12 weeks is safe and could be an option for individuals who are obese or overweight.”

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They added that future research should assess blood lipid profiles, blood glucose levels and inflammatory markers in order to gain a better understanding of the mechanisms of action.

Source: Journal of Functional Morphology and Kinesiology. 2025, 10(2), 202. doi: https://doi.org/10.3390/jfmk10020202. “Effects of High-Intensity Intermittent Training Combined with Asparagus officinalis Extract Supplementation on Cardiovascular and Pulmonary Function Parameters in Obese and Overweight Individuals: A Randomized Control Trial”. Authors: Padkao, T. et al.

Fitness

Put the fun back in your fitness routine with this 10-minute follow-along workout from The Curvy Girl Trainer Lacee Green

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Put the fun back in your fitness routine with this 10-minute follow-along workout from The Curvy Girl Trainer Lacee Green

Ever feel like beginner-friendly workouts are anything but?

That’s how BODi Super Trainer Lacee Green felt, so she devised a three-week, entry-level program designed for genuine newcomers to exercise—or those just getting back into it.

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Higher fitness levels linked to lower risk of depression, dementia – Harvard Health

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Higher fitness levels linked to lower risk of depression, dementia – Harvard Health
research review

People with high cardiorespiratory fitness were 36% less likely to experience depression and 39% less likely to develop dementia than those with low cardiorespiratory fitness. Even small improvements in fitness were linked to a lower risk. Experts believe that exercise’s ability to boost blood flow to the brain, reduce bodywide inflammation, and improve stress regulation may explain the connection.

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These 20-Minute Burpee Workouts Replaced His Entire Gym Routine – and Transformed His Physique

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These 20-Minute Burpee Workouts Replaced His Entire Gym Routine – and Transformed His Physique

While many swear by them, most people see burpees as a form of punishment – usually dished out drill sergeant-style by overzealous bootcamp PTs. Often the final blow in an already brutal workout, burpees are designed to test cardiovascular fitness, muscular endurance and mental grit. Love them or loathe them, they deliver every time.

For Max Edwards – aka Busy Dad Training on YouTube – they became a simple but highly effective way to stay fit and lean during lockdown. Once a committed powerlifter, spending upwards of 80 minutes a day in the gym, he was forced to overhaul his approach due to fatherhood, lockdown and a schedule that no longer allowed for long, structured lifting sessions.

‘Even though I was putting in hours and hours into the gym and even though my physique was pretty good, I wasn’t becoming truly excellent at any physical discipline,’ he explained in a YouTube video.

‘I loved the intentionality of training,’ says Edwards. ‘The fact that every session has a point, every rep in every set is helping you get towards a training goal, and I loved that there was a clear way of gauging progression – feeling like I was developing competence and moving towards mastery.’

Why He Walked Away From Powerlifting

Despite that structure, Edwards began to question whether powerlifting was sustainable long-term.

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‘My sessions were very taxing on my central nervous system. I was exhausted between sessions. It felt as if I needed at least nine hours of sleep each night just to function.’

He also noted that his appetite was consistently high.

But the biggest drawback was time.

‘I could not justify taking 80 minutes a day away from my family for what felt like a self-centred pursuit,’ he says.

A Simpler Approach That Stuck

‘Over the course of that year I fixed my relationship with alcohol and I developed, for the first time in my adult life, a relationship with physical training,’ says Edwards.

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With limited time and no access to equipment, he turned to burpees. Just two variations, four times a week, with each session lasting 20 minutes.

‘My approach in each workout was very simple. On a six-count training day I would do as many six-counts as I possibly could within 20 minutes. On a Navy Seal training day I would do as many Navy Seal burpees as I could within 20 minutes – then in the next workout I would simply try to beat the number I had managed previously.’

This style of training is known as AMRAP – as many reps (or rounds) as possible.

The Results

Edwards initially saw the routine as nothing more than a six-month stopgap to stay in shape. But that quickly changed.

‘I remember catching sight of myself in the mirror one morning and I was utterly baffled by the man I saw looking back at me.’

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He found himself in the best shape of his life. His energy levels improved, his resting heart rate dropped and his physique changed in ways that powerlifting hadn’t quite delivered.

‘It has been five years since I have set foot in a gym,’ he says. ‘That six-month training practice has become the defining training practice of my life – and for five years I have trained for no more than 80 minutes per week.’

The Burpee Workouts

1/ 6-Count Burpees

20-minute AMRAP, twice a week

How to do them:

  • Start standing, feet shoulder-width apart
  • Crouch down and place your hands on the floor (count 1)
  • Jump your feet back into a high plank (count 2)
  • Lower into the bottom of a push-up (count 3)
  • Push back up to plank (count 4)
  • Jump your feet forward to your hands (count 5)
  • Stand up straight (count 6)

20-minute AMRAP, twice a week

How to do them:

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  • Start standing, feet shoulder-width apart
  • Crouch down and place your hands on the floor
  • Jump your feet back into a high plank
  • Perform a push-up (chest to floor)
  • At the top, bring your right knee to your right elbow, then return
  • Perform another push-up
  • Bring your left knee to your left elbow, then return
  • Perform a third push-up
  • Jump your feet forward
  • Stand or jump to finish

Headshot of Kate Neudecker

Kate is a fitness writer for Men’s Health UK where she contributes regular workouts, training tips and nutrition guides. She has a post graduate diploma in Sports Performance Nutrition and before joining Men’s Health she was a nutritionist, fitness writer and personal trainer with over 5k hours coaching on the gym floor. Kate has a keen interest in volunteering for animal shelters and when she isn’t lifting weights in her garden, she can be found walking her rescue dog.

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