Health
What is ketamine therapy? Mormon reality stars tout controversial treatment
Season 2 of the reality show “The Secret Lives of Mormon Wives” depicted one couple — Jen and Zac Affleck — as they went through ketamine therapy, which they claimed saved their marriage.
What is ketamine, and can it really benefit relationships?
An anesthetic used to induce sleep before and after surgery, according to Cleveland Clinic, ketamine is also used illegally as a recreational drug.
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The Alcohol and Drug Foundation (ADF) describes ketamine as a “dissociative drug,” meaning it causes people to feel “separated or detached” from their bodies or physical surroundings.
In recent years, ketamine has been used as an alternative therapy for treatment-resistant depression (TRD).
Season 2 of “The Secret Lives of Mormon Wives” depicted one couple — Jen and Zac Affleck — going through ketamine therapy, which they claimed in interviews saved their marriage. Jen Affleck is shown third from right. (Getty Images)
“It can be a party drug, and it can be abused, but I think if you have the right intention and you do it in the proper setting with a doctor, it can be super impactful,” Zac Affleck said in an interview with Women’s Health.
As far as personal beliefs, “there’s nothing in the Mormon guidelines that says you can’t do ketamine, but it’s in the gray area,” Affleck added.
Ketamine as depression treatment
In 2019, the U.S. Food and Drug Administration (FDA) approved a derivative of ketamine in a nasal spray format (Spravato, or S-ketamine) for treatment-resistant depression and suicidal ideation.
Some clinical studies have shown that ketamine therapy can be effective in treating severe depression in veterans. (Julia Rendleman for The Washington Post via Getty Images; iStock)
Some clinical studies have shown that ketamine therapy can be effective in treating severe depression in veterans.
“Ketamine acts like an antidepressant that can help distract someone from negative thoughts and feelings in a relatively short amount of time,” Rolando Larice, M.D., medical director at Sana Lake Recovery in Missouri, told Fox News Digital.
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The drug is believed to create more connections between brain cells, a process thought to ease depression and decrease suicidal thoughts, according to Mayo Clinic.
Dr. Justin Gerstner, psychiatrist and chief medical officer at Ellie Mental Health in Minnesota, previously told Fox News Digital that he uses ketamine therapy in his own practice.
“Ketamine acts like an antidepressant that can help distract someone from negative thoughts and feelings in a relatively short amount of time,” one doctor told Fox News Digital. (iStock)
“It’s been quite transformative for a lot of our clients,” he said.
One practice administers ketamine to clients via IV injection, partnered with psychotherapy.
Gerstner’s practice usually administers ketamine to clients via IV injection in two- to three-hour sessions, partnered with psychotherapy before and after treatment.
It is intended to be used in combination with antidepressant pills only under the supervision of a medical professional.
Risks and limitations
At high doses, the drug can cause adverse health issues that affect cardiovascular, respiratory and neurologic function, which can be fatal, said the American Addiction Centers website.
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Some risks include elevated blood pressure, difficulty breathing, amnesia, seizures, addiction, problems with judgment and coordination, and a lower urinary tract irritation called ulcerative cystitis, according to the same source.
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“Common causes of overdose death include excess sedation, respiratory failure, low blood pressure, cardiac arrhythmia, coma and seizures,” Dr. Marc Siegel, Fox News’ senior medical advisor, previously told Fox News Digital.
Larice cautioned that ketamine does carry a risk of addiction or dependency.
If other treatments haven’t been effective in treating mental health conditions, some doctors recommend ketamine IV therapy treatment as an alternative option. (iStock)
While ketamine IV therapy could be an alternative option if other treatments haven’t been effective for mental health conditions, experts urge caution.
“People may see celebrities like Jen Affleck make claims that ketamine therapy saved her marriage, but if it’s shown as a quick fix to solve all of your problems rather than a step toward healing, that’s when it can be dangerous,” Larice cautioned.
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It is important for the IV treatment to be monitored by medical professionals in case dangerous side effects occur, he said.
Fox News Digital’s Melissa Rudy contributed reporting.
Health
Health experts react as Andrew Huberman backs Trump admin’s new food pyramid
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The Trump administration has taken a new approach to the food pyramid.
The Department of Health and Human Services (HHS) announced new guidelines on Wednesday with an updated, inverted pyramid. The top of the pyramid, which is now the wider part of the structure, is built on meat, fats, fruits and vegetables, while whole grains are at the narrow bottom.
This follows HHS Secretary Robert F. Kennedy Jr.’s mission to “Make America Healthy Again” (MAHA), aimed at addressing chronic disease, childhood illnesses and ultraprocessed foods.
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“The new guidelines recognize that whole, nutrient-dense food is the most effective path to better health and lower health care costs,” Kennedy said during a press briefing in Washington, D.C.
“Protein and healthy fats are essential, and were wrongly discouraged in prior dietary guidelines. We are ending the war on saturated fats.”
The Trump administration announces the 2025-2030 Dietary Guidelines for Americans, putting “real food” back at the center of health. (realfood.gov)
The HHS secretary rallied against refined carbohydrates, food additives and added sugar, highlighting the health risks associated with sugar-sweetened beverages.
Kennedy’s main message to Americans was to “eat real food.”
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The announcement triggered reactions from top health and wellness voices, including Stanford neuroscientist Dr. Andrew Huberman, host of the “Huberman Lab” podcast.
In a post on X, Huberman shared the White House’s graphic of the new pyramid, praising the decisions that were made.
“Oatmeal (and I think that’s rice and sourdough) made the cut!” he commented. “In all seriousness, assuming overall calories are kept in check and people exercise & get sun(day)light, this looks spot on.”
He added, “Maybe up the veggies a bit, add low-sugar fermented foods like sauerkraut & this is great.”
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Huberman said in a thread on the same post that Americans “don’t have to eat all the foods” shown in the diagram.
“You won’t see me drinking milk or eating shrimp,” he said. “Nothing against shrimp, I just don’t like the taste. Aversion to crustaceans.”
“Maybe up the veggies a bit, add low-sugar fermented foods like sauerkraut & this is great,” Huberman commented on X. (Chance Yeh/Getty Images for HubSpot; iStock)
The new guidelines received praise from other major health figures, including former FDA commissioner Dr. David Kessler.
“There should be broad agreement that eating more whole foods and reducing highly processed carbohydrates is a major advance in how we approach diet and health,” Kessler told The Associated Press.
“Protein and healthy fats are essential, and were wrongly discouraged in prior dietary guidelines.”
Dr. Bobby Mukkamala, president of the American Medical Association, shared in a statement that these guidelines “affirm that food is medicine and offer clear direction patients and physicians can use to improve health.”
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“The American Medical Association applauds the Administration’s new Dietary Guidelines for spotlighting the highly processed foods, sugar-sweetened beverages and excess sodium that fuel heart disease, diabetes, obesity and other chronic illnesses,” Mukkamala wrote.
The American Medical Association applauded the HHS for its updated nutrition guidelines. (iStock)
But not all feedback was positive.
Some people expressed concern about prioritizing red meat and dairy, while calling for the limitation of saturated fat.
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Neal Barnard, president of the Physicians Committee for Responsible Medicine, shared in a reaction to STAT that while the guidelines “do have one or two good points, emphasizing fruits and vegetables and limiting alcohol,” the guidelines are “for the most part a strong reflection of industry influence.”
Christopher Gardner, a nutrition expert at Stanford University, also spoke out against the new guidelines, as reported by NPR.
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“I’m very disappointed in the new pyramid that features red meat and saturated fat sources at the very top, as if that’s something to prioritize. It does go against decades and decades of evidence and research,” said Gardner, who was a member of the Dietary Guidelines Advisory Committee.
Fox News Digital’s Rachel Wolf, as well as Alexandria Hoff of Fox News, contributed reporting.
Health
Matt Damon’s Gluten-Free Diet Helped Him Lose 18 Pounds
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Health
Deadly cancer risk could drop with single 10-minute workout, study suggests
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A single 10-minute workout may trigger blood changes that help fight colon cancer.
That’s according to new research from scientists at Newcastle University, who found that exercise quickly changes the blood in ways that affect colon cancer cells in the lab.
In the study, the U.K. researchers exposed colon cancer cells to human blood serum collected immediately after exercise, finding that the cells repaired DNA damage faster and showed gene activity patterns linked to slower growth.
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The blood samples came from 30 adults who had just completed a short, high-intensity cycling workout that lasted about 10 to 12 minutes, according to a press release.
Even a 10-minute burst of intense exercise may send protective signals through the blood that affect colon cancer cells, researchers say. (iStock)
Samuel T. Orange, an associate professor at Newcastle University and one of the study’s authors, spoke with Fox News Digital about the findings.
“Our findings show that exercise rapidly triggers molecular changes in the bloodstream that can act directly on colon cancer cells, reshaping gene activity and supporting DNA damage repair,” he said.
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The results suggest that even brief activity can make a difference. “Every movement matters. Exercise doesn’t need to last hours or happen in a gym,” Orange added.
The research suggests that exercise quickly triggers changes in the blood that affect colon cancer cells and helps support DNA repair. (iStock)
One of the most surprising findings, according to the researcher, was how strong the biological response was after even a single workout.
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“Exercise altered the activity of more than 1,000 genes in colon cancer cells,” he shared.
Even brief bouts of activity can make a difference, the researcher said. (iStock)
The study findings suggest that the effect is driven by exercise-triggered molecules released into the bloodstream, sometimes referred to as “exerkines,” which act like chemical messengers and send signals throughout the body.
“Each time you exercise, you trigger biological signals that support health and resilience to diseases such as cancer, diabetes and heart disease,” Orange said.
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The researchers cautioned that the study was conducted using cancer cells grown in the laboratory, not in patients.
The findings are based on experiments using colon cancer cells grown in the lab, not studies conducted in people, the researchers noted. (iStock)
The study involved 30 healthy male and female volunteers between the ages of 50 and 78. Their blood samples were used to carry exercise-triggered signals to cancer cells grown in the lab.
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“These findings now need to be replicated in people with cancer,” Orange said. “We also need to better understand the longer-term effects of repeated exercise signals over time.”
Despite the limitations, the researcher said the findings strengthen the case for exercise as an important part of colon cancer prevention.
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“Each time you move your body and get a little breathless, you’re contributing to better health and may help influence biological processes linked to bowel cancer,” he added.
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