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What is ketamine therapy? Mormon reality stars tout controversial treatment

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What is ketamine therapy? Mormon reality stars tout controversial treatment

Season 2 of the reality show “The Secret Lives of Mormon Wives” depicted one couple — Jen and Zac Affleck — as they went through ketamine therapy, which they claimed saved their marriage. 

What is ketamine, and can it really benefit relationships?

An anesthetic used to induce sleep before and after surgery, according to Cleveland Clinic, ketamine is also used illegally as a recreational drug.

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The Alcohol and Drug Foundation (ADF) describes ketamine as a “dissociative drug,” meaning it causes people to feel “separated or detached” from their bodies or physical surroundings.

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In recent years, ketamine has been used as an alternative therapy for treatment-resistant depression (TRD).

Season 2 of “The Secret Lives of Mormon Wives” depicted one couple — Jen and Zac Affleck — going through ketamine therapy, which they claimed in interviews saved their marriage. Jen Affleck is shown third from right. (Getty Images)

“It can be a party drug, and it can be abused, but I think if you have the right intention and you do it in the proper setting with a doctor, it can be super impactful,” Zac Affleck said in an interview with Women’s Health.

As far as personal beliefs, “there’s nothing in the Mormon guidelines that says you can’t do ketamine, but it’s in the gray area,” Affleck added.

Ketamine as depression treatment

In 2019, the U.S. Food and Drug Administration (FDA) approved a derivative of ketamine in a nasal spray format (Spravato, or S-ketamine) for treatment-resistant depression and suicidal ideation.

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Some clinical studies have shown that ketamine therapy can be effective in treating severe depression in veterans. (Julia Rendleman for The Washington Post via Getty Images; iStock)

Some clinical studies have shown that ketamine therapy can be effective in treating severe depression in veterans.

“Ketamine acts like an antidepressant that can help distract someone from negative thoughts and feelings in a relatively short amount of time,” Rolando Larice, M.D., medical director at Sana Lake Recovery in Missouri, told Fox News Digital.

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The drug is believed to create more connections between brain cells, a process thought to ease depression and decrease suicidal thoughts, according to Mayo Clinic. 

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Dr. Justin Gerstner, psychiatrist and chief medical officer at Ellie Mental Health in Minnesota, previously told Fox News Digital that he uses ketamine therapy in his own practice.

“Ketamine acts like an antidepressant that can help distract someone from negative thoughts and feelings in a relatively short amount of time,” one doctor told Fox News Digital. (iStock)

“It’s been quite transformative for a lot of our clients,” he said.

One practice administers ketamine to clients via IV injection, partnered with psychotherapy. 

Gerstner’s practice usually administers ketamine to clients via IV injection in two- to three-hour sessions, partnered with psychotherapy before and after treatment.

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It is intended to be used in combination with antidepressant pills only under the supervision of a medical professional.

Risks and limitations

At high doses, the drug can cause adverse health issues that affect cardiovascular, respiratory and neurologic function, which can be fatal, said the American Addiction Centers website.

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Some risks include elevated blood pressure, difficulty breathing, amnesia, seizures, addiction, problems with judgment and coordination, and a lower urinary tract irritation called ulcerative cystitis, according to the same source.

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“Common causes of overdose death include excess sedation, respiratory failure, low blood pressure, cardiac arrhythmia, coma and seizures,” Dr. Marc Siegel, Fox News’ senior medical advisor, previously told Fox News Digital.

Larice cautioned that ketamine does carry a risk of addiction or dependency.

If other treatments haven’t been effective in treating mental health conditions, some doctors recommend ketamine IV therapy treatment as an alternative option. (iStock)

While ketamine IV therapy could be an alternative option if other treatments haven’t been effective for mental health conditions, experts urge caution.

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“People may see celebrities like Jen Affleck make claims that ketamine therapy saved her marriage, but if it’s shown as a quick fix to solve all of your problems rather than a step toward healing, that’s when it can be dangerous,” Larice cautioned.

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It is important for the IV treatment to be monitored by medical professionals in case dangerous side effects occur, he said.

Fox News Digital’s Melissa Rudy contributed reporting.

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New ways to prevent flu revealed in ‘accidental’ lab breakthrough, study finds

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New ways to prevent flu revealed in ‘accidental’ lab breakthrough, study finds

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An accidental lab discovery has opened the door to entirely new ways of preventing the flu.

While investigating how influenza replicates, researchers discovered that different flu strains use completely different strategies to infiltrate human cells, SWNS reported.

By targeting the specific molecules the viruses rely on, scientists found that they could block them from entering new cells and halt their replication altogether.

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Researchers say these “fundamental insights” into seasonal influenza highlight a clear path toward developing better preventive medications.

“The hope is that fundamental, curiosity-based research like this helps to pave the way for novel strategies to treat and prevent influenza infections,” principal investigator Dr. Emily Bruce, from the University of Vermont’s Larner College of Medicine, said in the SWNS report.

While investigating how influenza replicates, researchers discovered that different flu strains use completely different strategies to infiltrate human cells. (iStock)

While several flu strains cause illness, H1N1 and H3N2 influenza A viruses are the most common. However, current flu tests cannot differentiate between them, and clinical treatments are identical for both.

Although vaccines and antivirals are available, Bruce noted a “dire” need for better medications to stop the virus from spreading cell to xxcell.

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“You don’t get sick when a virus is in one cell,” he noted. “You get sick because a virus replicates itself and goes into many more cells.”

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The study, which was published in The Journal of Virology, originally aimed to map how viral RNA segments are transported within cells to create new viral particles.

The team used H1N1 and H3N2 viruses isolated from the nasal passages of positive patients in 2022.

Clinical treatments remain identical for both primary strains of the flu virus. (iStock)

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During the investigation, the team unexpectedly stumbled upon a cellular pathway that blocked the virus from entering lung cells, SWNS reported.

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The data revealed that when a specific human protein called Rab11B was depleted, H3N2 viruses failed to enter human lung cells. H1N1 viruses were completely unaffected.

Using reverse genetics, the team mapped this defect and uncovered a brand-new, H3N2-specific role for Rab11B during viral entry.

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This discovery challenged the scientific assumption that all flu viruses enter cells the same way.

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“Viruses are like pirates from different countries hijacking someone’s ship,” Bruce said. “Different viruses, like different types of pirates, use different methods to get onboard.”

This discovery challenged the scientific assumption that all flu viruses enter cells the same way. (iStock)

“We had previously thought that all flu viruses used the same way to get into a cell, but we discovered that this is not true,” she went on. “H1N1 and H3N2 need different proteins to get in, and if you get rid of the right protein, a specific virus can’t get in.”

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While these findings identify a critical cellular pathway for viral entry, the study was conducted using isolated cells, the researchers acknowledged.

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Further research is needed to determine whether blocking the protein is safe and effective within a live, complex human respiratory system.

Bruce and the team hope to conduct further research to determine whether this Rab11B-dependency is a fundamental property of H3N2, or if it’s a trait unique to currently circulating flu strains.

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One extra serving of processed meat a day linked to higher cancer risk

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One extra serving of processed meat a day linked to higher cancer risk

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Eating processed meat like ham, sausage and bacon may be linked to a higher risk of certain types of cancer, according to new research.

While health organizations have already confirmed that processed meat can contribute to colon cancer, this study looked closer at cancers in the upper digestive tract, where the link has historically been less clear.

To understand these connections, researchers from the European Prospective Investigation into Cancer and Nutrition (EPIC), one of the world’s largest long-term nutrition and cancer cohorts, tracked the health and diets of 450,112 people across Europe for an average of 14 years. 

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The study group included 131,426 men and 318,686 women, according to the study’s press release.

During the follow-up period, 876 people developed stomach cancer and 215 people developed esophageal adenocarcinoma, which is cancer of the tube connecting the mouth to the stomach.

For female participants, eating both processed meat and white meat was linked to an increased risk of developing the disease. (iStock)

Researchers tracked where the stomach cancers grew, separating them into the upper part of the stomach near the throat and the lower part of the stomach.

The researchers also sorted the tumors into two categories based on how the cancer cells appeared under a microscope: intestinal, which forms more organized structures, and diffuse, in which the cells are more scattered throughout the tissue.

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After adjusting for other lifestyle factors, the researchers found that for every extra 30 grams of processed meat a person ate per day, their overall risk of stomach cancer went up by 9%. Eating that same extra 30 grams a day was also linked to a 13% higher risk of esophageal adenocarcinoma.

A standard single slice of regular deli-sliced ham or lunch meat averages around 28 grams, according to USDA data and nutritional tracking databases.

An extra 20 grams of white meat, such as chicken and turkey, was linked to a 12% higher risk of cancer in the main body of the stomach. (iStock)

An extra 20 grams of white meat, such as chicken or turkey, was linked to a 12% higher risk of cancer in the main body of the stomach, the researchers noted.

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The study also revealed differences between men and women. For male participants, only processed meat showed a clear, statistically significant link to a higher risk of stomach cancer. For female participants, however, eating both processed meat and white meat was linked to an increased risk.

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These findings align with global health benchmarks, particularly those established by the World Health Organization’s International Agency for Research on Cancer.

The agency has long classified processed meat as a known human carcinogen, primarily due to its strong, well-documented links to colorectal cancer.

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However, health organizations have also consistently pointed to a potential, yet less definitive, relationship between these meats and cancers of the stomach.

Eating 30 grams of processed meat a day, or the equivalent to one slice of ham, was linked to a 13% higher risk of esophageal adenocarcinoma. (iStock)

Further scientific investigation is needed to confirm the findings and to account for other underlying risk factors, such as certain stomach infections, which could interact with dietary habits.

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A key limitation of the study is its reliance on self-reported diets, which can sometimes lead to inaccuracies in how participants recall their meat consumption over time, the researchers noted.

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The findings were published in the International Journal of Cancer.

Fox News Digital reached out to the researchers requesting comment.

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The Surprising Hormone That Could Make Menopause Weight Loss Easier

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The Surprising Hormone That Could Make Menopause Weight Loss Easier


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The Hormone That Could Make Menopause Weight Loss Easier




















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