Health
Ellen DeGeneres has osteoporosis: Here's what to know about the painful bone condition
Longtime talk show host Ellen DeGeneres announced last week that she has been diagnosed with osteoporosis, as well as OCD (obsessive-compulsive disorder) and ADHD (attention-deficit/hyperactivity disorder).
During her final Netflix special “For Your Consideration,” DeGeneres, 66, opened up about her triple diagnosis, noting that she took a bone density test recommended by her doctor and learned she had “full-on osteoporosis.”
“I don’t even know how I’m standing up right now. I’m like a human sandcastle. I could disintegrate in the shower,” she told the audience.
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DeGeneres went on to admit that “it’s hard to be honest about aging and seem cool.”
Ellen DeGeneres joins “The Late Late Show with James Corden” as a guest on May 4, 2021. The longtime talk show host announced last week that she was diagnosed with osteoporosis, as well as OCD and ADHD. (Terence Patrick/CBS via Getty Images)
“I had excruciating pain one day and I thought I tore a ligament or something, and I got an MRI, and they said, ‘No, it’s just arthritis.’ I said, ‘How did I get that?’ And he said, ‘Oh it just happens at your age,’” she said.
Dr. Gbolahan Okubadejo, board-certified spine surgeon at The Institute for Comprehensive Spine Care in New Jersey, weighed in on DeGeneres’ diagnosis.
“Ellen still appears to have great posture and appears to be very active and healthy,” he told Fox News Digital.
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“Depending on the degree of osteoporosis she was diagnosed with, she has a great chance to have a normal life,” he went on.
“It’s important for her to be well-educated about the treatments and lifestyle modifications recommended by her doctor, and be a great patient by following those instructions.”
What is osteoporosis?
Osteoporosis is a “bone disease that develops when bone mineral density and bone mass decreases, or when the structure and strength of bone changes,” according to the National Institute of Arthritis and Musculoskeletal and Skin Diseases.
The disease can lead to a decrease in bone strength, which can increase the risk of broken bones.
Nearly 20% of women aged 50 and older have osteoporosis, according to the CDC.
“Osteoporosis occurs when the body loses too much bone mass or doesn’t produce enough bone to maintain healthy density,” Okubadejo said.
This causes the bone to become weak or brittle.
“Although certain populations are more vulnerable to osteoporosis, it’s often associated with aging, hormonal changes associated with age, lifestyle factors or mineral/vitamin deficiencies,” added Okubadejo.
The most common breaks in osteoporosis patients occur in the hip, wrist and spine, according to Mayo Clinic. (Randy Holmes/Disney General Entertainment Content via Getty Images; iStock)
Osteoporosis can cause the bones to become so weak and brittle that a fall or even mild stress like coughing can cause a break, Mayo Clinic reported.
Nearly 20% of women aged 50 and older have osteoporosis, according to the Centers for Disease Control and Prevention (CDC).
Symptoms and risk factors
Early-stage bone loss typically does not show any symptoms, according to Mayo Clinic.
Once bones are weakened, that can lead to back pain, loss of height, stooped posture and easy bone breakage.
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Osteoporosis can occur in men and women alike, but Mayo Clinic specified that older white and Asian women who are past menopause have the highest risk.
Men and women with small body frames tend to be more susceptible, as they have “less bone mass to draw from as they age,” the clinic noted.
The condition is also more likely to occur in people who have hormone imbalances, have undergone gastrointestinal surgery, have low calcium intake or experience disordered eating, according to the same source.
“Osteoporosis occurs when the creation of new bone doesn’t keep up with the loss of old bone,” according to Mayo Clinic. (iStock)
Those with a family history of osteoporosis may also face a higher risk.
People who have taken corticosteroid medicines for conditions like seizures, gastric reflux, cancer and transplant rejection are more susceptible, as are those with celiac disease, inflammatory bowel disease, kidney or liver disease, multiple myeloma and rheumatoid arthritis.
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Brain aging may accelerate after cancer treatment, study suggests
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Surviving cancer as a child or young adult may have a lasting impact on aging, new research suggests.
Researchers at the University of Rochester Medical Center looked at whether life-saving treatments, like chemotherapy and radiation, could speed up biological aging.
They also aimed to determine whether this age acceleration was linked to cognitive issues related to memory, focus and learning.
The team analyzed blood samples from a group of 1,400 long-term survivors treated at St. Jude Children’s Research Hospital, using epigenetic clocks — tools that estimate biological age by examining chemical tags on DNA.
Biological age is determined based on damage the cells accumulate over time, versus chronological age, which is measured by how long someone has been alive, according to scientists.
Biological age is determined based on the damage cells accumulate over time, according to scientists. (iStock)
“These well-established aging-related biomarkers have previously been associated with neurocognitive impairment and decline in older non-cancer populations, particularly in cognitive domains related to aging and dementia, such as memory, attention and executive function,” the study stated.
Most of the group consisted of acute lymphoblastic leukemia survivors, or Hodgkin lymphoma survivors. Participants were at least five years past their treatment, though some had survived for several decades.
They underwent neurocognitive testing to measure their attention span, memory and information processing speed.
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Chemotherapy was found to have the greatest impact on aging acceleration. The study suggests the treatment can alter DNA structure and cause cellular damage.
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“It’s no surprise to find out that young people with cancer who have chemo early in life are affected in terms of long-term aging,” Dr. Marc Siegel, senior medical analyst for Fox News, told Fox News Digital.
Participants underwent neurocognitive testing to measure their attention span, memory and speed of information processing. (iStock)
Researchers also found that cellular aging was closely linked to cognitive performance, as survivors of a higher biological age had more difficulty with memory and attention.
“Chemo poisons and damages cellular function — hopefully the cancer cells more than normal cells, but there is a significant impact on normal cells as well,” said Siegel, who was not involved in the study.
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“There is also something called ‘chemo brain,’ which causes at least temporary difficulty with memory, concentration, word finding and brain fog,” the doctor added.
The research team hopes to use these findings to focus on intervention efforts, specifically by determining when accelerated aging begins.
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“Young cancer survivors have many more decades of life to live,” lead study author AnnaLynn Williams, PhD, said in a press release. “If these accelerated aging changes are occurring early on and setting them on a different trajectory, the goal is to intervene to not only increase their lifespan, but improve their quality of life.”
The team hopes this research will help in the development of early intervention tools that aim to prevent cognitive decline. (iStock)
There were some limitations to the study. The researchers could not adjust for chronic health conditions or education because they are directly impacted by treatment.
Additionally, the study only looked at the survivors at a single point of time, so it could not directly prove causation.
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The study was published in the journal Nature Communications.
Fox News Digital reached out to the researchers for comment.
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