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Ozempic and other GLP-1 drugs could reduce arthritis symptoms in some, experts claim

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Ozempic and other GLP-1 drugs could reduce arthritis symptoms in some, experts claim

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Popular medications for weight loss and diabetes control could have a surprising bonus benefit, according to some anecdotal reports.

Some people with rheumatoid arthritis who use GLP-1 drugs — such as Wegovy and Ozempic — have reported an improvement in the severity and frequency of their arthritic symptoms.

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It has been “well-established” that autoimmune patients who also have obesity “fare worse” than those who are at a healthy weight, according to Dr. Elizabeth Ortiz, M.D., a Texas-based rheumatologist and clinical adviser at WellTheory, a platform specializing in autoimmune disease treatment.

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“Any improvements in joint pain or joint inflammation are likely due to a combination of factors, of which weight loss is only one,” she told Fox News Digital.

“Our understanding of the interplay between obesity, adipose tissue and inflammation is incomplete, so as of today, it is difficult to ascribe an improvement in joint pain to any particular cause,” she continued in a written statement. 

Some people with rheumatoid arthritis who use GLP-1 drugs — such as Wegovy and Ozempic — have reported an improvement in the severity and frequency of their arthritic symptoms. (iStock)

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“We are beginning to learn of the direct anti-inflammatory effects of these medications — and that, with weight loss, is likely to be of benefit for autoimmune patients.”

Does this mean GLP-1s could be prescribed eventually for arthritic patients?

WEIGHT-LOSS MEDICATIONS ARE NOT EFFECTIVE WITHOUT ‘NUTRITION THERAPY,’ EXPERTS SAY

“There are certainly compelling anecdotes and emerging research into the anti-inflammatory effects of these medications,” said Ortiz, “but we will need dedicated studies evaluating their effectiveness in conditions such as rheumatoid arthritis or psoriatic arthritis before they become a part of standard care.”

What we may see sooner, she predicted, is the use of GLP-1s as a means of addressing obesity and metabolic syndrome in those with autoimmune arthritis. 

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“These medications could reduce rheumatoid arthritis symptoms and improve patients’ quality of life by addressing underlying inflammation and obesity, according to a recent meta-analysis,” a doctor told Fox News Digital. (iStock)

“Obesity has been associated with worse autoimmune and inflammatory symptoms and with poorer response to standard therapy,” she said. 

“Those with rheumatoid arthritis and other autoimmune diseases also carry a higher risk of cardiovascular disease than those without these conditions, and the addition of GLP-1 therapy to their immunomodulating therapy may prove to be a successful combination.”

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There are some potential risks to consider, the expert noted.

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In addition to having a higher risk of cardiovascular disease, those with autoimmune diseases are more likely to have osteoporosis, a condition of weakened bones that can lead to fractures.

“This can be a consequence of low muscle mass, something we are seeing in many taking the GLP-1s,” Ortiz said.

“Obesity is a gateway disease underpinning nearly all non-infectious age-related diseases.”

“This will need to be paid special attention to and weighed when determining how best to utilize these medications in autoimmune patients.”

The other potential limitation with the use of GLP-1s is cost, she added. 

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“Autoimmune drug spend is already very high, and together with safety and effectiveness, the cost of GLP-1 treatment needs to be considered,” Ortiz said.

Dr. Brett Osborn, a Florida neurologist and longevity expert at Senolytix, has been a longtime proponent of semaglutide drugs — including Wegovy, Ozempic and Zepbound — which belong to the GLP-1 class of medications. 

Dr. Brett Osborn, a Florida neurologist and longevity expert at Senolytix, said obesity exacerbates inflammation throughout the body, primarily through visceral fat. He’s been a longtime proponent of semaglutide drugs. (Dr. Brett Osborn)

“These medications could reduce rheumatoid arthritis symptoms and improve patients’ quality of life by addressing underlying inflammation and obesity, according to a recent meta-analysis,” Osborn told Fox News Digital.

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Rheumatoid arthritis is marked by chronic inflammation, joint pain and flare-ups, the doctor noted, and those with higher body fat and BMIs face a greater risk of developing the condition.

“Why? Because obesity exacerbates inflammation throughout the body, primarily through visceral fat (the fat around your abdominal organs), which secretes cytokines, chemical mediators that heighten inflammation,” Osborn said. 

Cost could be a limitation of using GLP-1 drugs for arthritis. “Autoimmune drug spend is already very high, and together with safety and effectiveness, the cost of GLP-1 treatment needs to be considered,” one doctor said. (Michael Siluk/UCG/Universal Images Group via Getty Images)

“This chronic inflammation can worsen RA symptoms and reduce the effectiveness of standard treatments,” the doctor added.

These medications help to reduce people’s consumption of simple carbohydrates — such as bread, pasta and rice — that contribute significantly to inflammation, according to Osborn. 

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“By curbing appetite and encouraging healthier eating patterns, GLP-1 drugs help decrease the consumption of these inflammation-triggering foods.”

                                       

Beyond rheumatoid arthritis, GLP-1 drugs can also help fight systemic lupus erythematosus (SLE), inflammatory bowel disease (IBD) and other autoimmune conditions, the doctor noted. 

“Targeting obesity first can improve overall health and reduce risks of conditions like heart attacks and strokes as well,” he added.

In addition to having a higher risk of cardiovascular disease, those with autoimmune diseases are more likely to have osteoporosis, a condition of weakened bones that can lead to fractures. (iStock)

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“Obesity is a gateway disease underpinning nearly all non-infectious age-related diseases.”

GLP-1 drugs offer “exciting potential” for managing rheumatoid arthritis and other inflammatory diseases, according to Osborn. 

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“Their ability to reduce inflammation and promote healthier eating patterns could significantly improve patients’ quality of life.”

Osborn noted, however, that more research is needed to fully understand the impact of GLP-1 drugs on autoimmune diseases. 

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GLP-1 drugs offer “exciting potential” for managing rheumatoid arthritis and other inflammatory diseases, a doctor said. (iStock)

“These genetic diseases are fueled by obesity-associated inflammation — however, an ‘obesity-first’ approach may not suit all patients and could lead to poorly controlled inflammation if underlying conditions are not addressed.”

Other potential risks associated with GLP-1 medications, such as the muscle loss Ortiz mentioned, “can be mitigated with careful surveillance by a seasoned physician,” said Osborn.

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Novo Nordisk, the manufacturer of Ozempic and Wegovy, declined to comment on the potential arthritis impact when contacted by Fox News Digital.

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One walking habit could signal a healthier brain after 80, scientists say

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One walking habit could signal a healthier brain after 80, scientists say

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Older adults identified as “super movers” are about half as likely to develop cognitive impairment than their peers.

That’s according to a recent study led by Stony Brook Medicine in New York, which evaluated the cognitive function of 4,000 adults 80 and over who participated in multiple aging and longevity studies over several years.

Among this group, 6% to 10% were classified as super movers, which means they walk at a much faster pace than others of the same age and gender — at speeds comparable to people three decades younger.

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The super movers were found to have about half the risk of cognitive decline compared to seniors with typical gait speed.

The findings were published in the journal Neurology on June 16.

Older adults identified as “super movers” are about half as likely to develop cognitive impairment than their peers. (iStock)

“The study reinforces that mobility and brain health are closely connected,” lead study author Dr. Joe Verghese, MD, neurologist at Stony Brook Medicine, told Fox News Digital. “This suggests that preserving mobility may be an important marker of healthy brain aging and resilience.”

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The most intriguing finding, according to Verghese, was that super movers maintained cognitive function despite having similar dementia-related brain changes as their peers.

In postmortem brain analysis, there was no difference in dementia-related pathologies between the super movers and the slower walkers, the study stated.

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“This suggests they may possess resilience mechanisms that help preserve brain function even in the presence of age-related changes,” he said. “Understanding these resilience factors could lead to new strategies for promoting healthy brain aging.”

As the study was observational, there were some limitations, and it does not prove that walking faster prevents dementia, the researchers noted.

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Super movers were found to have about half the risk of cognitive decline compared to seniors with typical gait speed. (iStock)

“Other factors, such as cardiovascular health, physical fitness or genetics, may also contribute to both faster walking and better cognitive outcomes,” Verghese said.

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This study adds to growing evidence that what’s good for the heart and muscles also benefits the brain, he noted, adding that “staying physically active remains one of the most effective, evidence-based ways to support healthy aging.”

“Walking speed is best viewed as a marker of overall health, not a treatment.”

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“The broader message is that physical activity is important at any age,” Verghese said. “Walking is an easy step-up point because you don’t need any special equipment. You can do it inside or outdoors, and you can do it on a regular basis. You can walk with a dog, you can walk with a friend.”

Any activity is beneficial if it’s done regularly and with the right intensity, he added.

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Rather than just trying to walk faster, the neurologist recommends that seniors focus on maintaining mobility through regular physical activity, strength training, balance exercises and good cardiovascular health.

“Walking speed is best viewed as a marker of overall health, not a treatment,” Verghese noted.

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Major public health guidelines from the CDC and U.S. Physical Activity Guidelines recommend at least 150 minutes of moderate-intensity aerobic activity each week, such as brisk walking.

Major public health guidelines from the CDC and U.S. Physical Activity Guidelines recommend at least 150 minutes of moderate-intensity aerobic activity each week, such as brisk walking. (iStock)

This can be achieved by walking 30 minutes a day, five days a week, or about 20 to 25 minutes most days. Another option is to engage in shorter sessions that add up over the day.

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“You have to do it within your health limitations and medical conditions,” Verghese advised. “So if there are any medical concerns, I would get your physician to clear you before starting exercise.” The good thing about walking, he added, is that you can start at a slow pace and then gradually build up to a brisker pace.

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“And then adding on strength and balance training, whatever age you are, I think is also important.”

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I Tried the Viral Gelatin Weight-Loss Recipe—Here’s My Honest Take

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I Tried the Viral Gelatin Weight-Loss Recipe—Here’s My Honest Take


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I Tried the Viral Gelatin Weight-Loss Recipe: Does It Really Work?




















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Dr Oz warns Medicare scammers are stealing billions — and your personal information could be next

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Dr Oz warns Medicare scammers are stealing billions — and your personal information could be next

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Medicare fraud is a multibillion-dollar problem that government officials say threatens both taxpayer dollars and Americans’ personal identities.

In a July 6 interview with Fox News Digital at the Great American State Fair in Washington, D.C., Dr. Mehmet Oz warned that every dollar stolen through Medicare fraud is a dollar taxpayers lose – a problem that has worsened since the COVID pandemic.

“If I had to just pick one thing to focus on to make healthcare more affordable in America, I’d go to health fraud and all the waste and abuse that accompanies it,” said Oz, who is the administrator of the Centers for Medicare & Medicaid Services. “And just to put this in perspective, we think it’s about $100 billion a year.”

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Medicare fraud can include billing for services that were never provided, overcharging for medical equipment, using stolen patient or doctor information, or performing unnecessary procedures, according to the U.S. Government Accountability Office.

CMS administrator Dr. Mehmet Oz is pictured on stage at the Great American State Fair in Washington, D.C., on July 6, 2026. (Angelica Stabile/Fox News Digital)

As the Trump administration ramped up efforts to combat fraud, CMS reported $41.9 billion in Medicare program integrity savings in 2025, up 59% from $26.3 billion in 2024.

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Medicare fraud not only harms the federal budget and steals from taxpayers, but exposes seniors to identity theft, unnecessary care, higher premiums and reduced access, Oz cautioned.

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Removing corruption from the healthcare system will have the greatest impact among seniors, since “so much of the fraud is perpetrated against them,” the administrator said.

“I’m talking about people tricking seniors to give up their Medicare beneficiary numbers, which is like a credit card basically,” he said. “These scammers can take those numbers and use them for all kinds of illegitimate purposes.”

“If I had to just pick one thing to focus on to make healthcare more affordable in America, I’d go to health fraud and all the waste and abuse that accompanies it,” said Oz. (Fox News Digital)

“People are stealing from you by pretending to send you drugs you don’t want, wheelchairs you don’t need, [and] services you never asked for or don’t benefit from,” Oz added.

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To prevent this, he shared his top advice for seniors: Do not give your Medicare beneficiary number to anybody, do not answer questions on a phone call from an unknown person and do not give away personal information.

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“These scammers are calling seniors, tricking them, and once they have key information, they can steal it,” he said. “And I won’t know it and you won’t know it.”

“We want to protect people who need these programs the most,” Oz went on. “You do that by making sure scoundrels don’t corrupt the systems and steal money out of the till that is designed to help folks in dire straits when they’re vulnerable and in need of services.”

Seniors should never share their Medicare information with unknown people, the administrator advised. (iStock)

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Removing fraud could “double the life expectancy of the trust fund that makes all this possible,” Oz predicted.

“If you’re worried about Medicare being there when you’re ready to retire in a couple decades, depending on how old you are, and you’re concerned that it might not last because of all the fraud that’s hitting it … you’ve got a good [reason to] worry,” he said.

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“If we take the fraud out, we could double the life expectancy, which means you, your kids, your kids’ kids … they could all benefit from this beautiful safety net program.”

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