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Voices: We’ve seen the impact of Utah’s groundbreaking genetic research. Federal funding cuts will be devastating for years to come.

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Voices: We’ve seen the impact of Utah’s groundbreaking genetic research. Federal funding cuts will be devastating for years to come.


These cuts will cause immense and largely irreversible damage to the successful American scientific enterprise.

(Francisco Kjolseth | The Salt Lake Tribune) A mass spectrometer at the University of Utah processes coral materials on Thursday, June 9, 2022, to be analyzed in the first step towards determining its usefulness in treating cancer. A team of researchers have found a potential anticancer compound found in coral.

As biomedical researchers, now retired, we are horrified by the deep cuts to the National Institutes of Health (NIH) and the National Science Foundation (NSF) proposed in the Trump administration’s budget for 2026. These cuts would cause immense and largely irreversible damage to the successful American scientific enterprise.

A 40% decrease for NIH and a 57% cut for NSF would lead to the cancellation of thousands of grants and the termination of thousands of research programs in areas ranging from basic cancer research to drug development to climate change remediation. It would also end the training of the next generations of investigators.

This is particularly sad for Utah, which has had a leading role in genetic research. The first NIH external research grant ever given came to the University of Utah in 1946 for investigation of muscular dystrophy and other genetic diseases. Funding for this grant was specifically promoted by Utah Senator Elbert Thomas.

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Our state has been eminent in genetics research partly due to early efforts like this one and partly to the willing cooperation of large Utah families and the genealogical records generously made available to medical research by the Church of Jesus Christ of Latter-day Saints.

In the mid-1980’s, the Department of Human Genetics was established at the U. with Drs. Ray White and Ray Gesteland as co-chairs. White was the first in the world to apply a new technique of genetic mapping that sparked an era of rapid disease gene discovery. Among a long list of successes here in Utah were genes associated with colon cancer, retinoblastoma, neurofibromatosis, hypertension and cardiac disorders, just to name a few.

Expertise in disease gene identification attracted a steady stream of young clinicians to Utah, many of whom went on to eminent careers; for example, Richard Lifton is now President of Rockefeller University, and Mark Keating who was a Director at Novartis and Chief Scientific Officer at Yarrow Biotechnology.

With the advent of new modalities of disease gene identification, such as whole genome sequencing (WGS), Utah remained in the forefront of using genetics for personalized medicine. Lynn Jorde, of the Department of Human Genetics and his former student and colleague Michael Bamshad, now at the University of Washington — were the first to use WGS to identify disease genes in families. Their efforts were expanded by Joshua Bonkovsky and colleagues in a pilot program between the U. and Primary Children’s Hospital to use WGS on infants brought to the neonatal Intensive care unit, so that earlier diagnosis could lead to earlier treatment.

Beyond gene discovery, Utah has been a leader in other areas of basic science that have had significant impacts. Nobel Prize winner, Mario Capecchi, developed a method to make specific, targeted changes in the DNA of mice. His discoveries led to the generation of many thousands of novel strains of mice, some of them carrying mouse versions of human disease genes. Studies of these mice in labs around the world have led to insights into the resulting physiological deficits and to the development of treatment protocols for people.

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Current genetic treatments offered at the U. include molecular therapies for spinal muscular atrophy and Duchenne muscular dystrophy. Researchers at the Moran Eye Center have been at the forefront in studying age-related macular degeneration (AMD), the leading cause of blindness in adults. After identifying genes responsible for AMD, doctors at Moran initiated a clinical study using gene therapy to treat and hopefully cure this disease.

We have cited a tiny percentage of the amazing achievements that have emerged from research in Utah, almost all of which were supported by long-term funding from NIH. While there are undoubtedly places in the NIH budget where sensible savings might be achieved, no justification has been given for the severe cuts that are now proposed.

Loss of the federal funding base for work such as we describe would devastate the people and institutions that generate these advancements in Utah and across the country for years, if not decades. Our hope is that by contacting our congressional legislators, we might effect changes that would prevent the devastating consequences of the proposed legislation.

(Jerry Kaplan) Jerry Kaplan, Ph.D., joined the University of Utah faculty in 1980 and retired as an Emeritus Professor in 2017.

Jerry Kaplan, Ph.D., joined the University of Utah faculty in 1980 and retired as an Emeritus Professor in 2017. He was a member of the Department of Pathology and an assistant dean for basic science at the University of Utah School of Medicine. Inspired by the climate of genetics in Utah he used research in the one-celled yeast organism to discover the basis for the human neurological/cardiac disorder called Friedreich’s Ataxia.

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(Dana Carroll) Dana Carroll, Ph.D., joined the University of Utah faculty in 1975 and retired in 2023 as former Chair and Distinguished Professor Emeritus of Biochemistry.

Dana Carroll, Ph.D., joined the University of Utah faculty in 1975 and retired in 2023 as former chair and distinguished professor emeritus of biochemistry. He is considered a pioneer in the field of genome editing – a method of making targeted changes in DNA that is now dominated by the CRISPR technology, which has been extremely effective as a research tool and is currently being deployed in novel therapies for genetic diseases.

The views expressed in this op-ed belong to the authors and don’t necessarily reflect those of their former employers.

The Salt Lake Tribune is committed to creating a space where Utahns can share ideas, perspectives and solutions that move our state forward. We rely on your insight to do this. Find out how to share your opinion here, and email us at voices@sltrib.com.



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Commentary: Recalling the Christmas of Catholic nuns and slave cabin singers

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Commentary: Recalling the Christmas of Catholic nuns and slave cabin singers


It’s not easy to pick the most memorable Christmas in Salt Lake City history.

There was, of course, that first Dec. 25 in Utah for the Mormon pioneers. They worked on Christmas Day 1847 but paused briefly for a simple feast.

The original Catholic church in Utah — the old St. Mary Magdalene on 200 East between South Temple and 100 South — hosted the city’s first Christmas midnight mass in December 1871.

The Salt Lake Tribune helped launch the tradition of downtown holiday decorating in 1945 and the old ZCMI store (where Macy’s now sits) on Main Street started decorating its windows with Christmas candy in the early 1970s. Temple Square’s Christmas light displays began in 1965.

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The Tabernacle Choir at Temple Square did not perform annual Christmas concerts until 2000. Willam Christensen choreographed “The Nutcracker” in California in 1944 but first brought it to Utah a decade later.

And memorable for all the wrong reasons, just after noon on Dec. 25, 1859, Salt Lakers had to dodge dozens of bullets from a Christmas Day gunfight that raged up and down Main Street.

Although all these holidays were unique, December 1875 stands out for me. It was the Christmas of Catholic nuns and slave cabin singers.

The Holy Cross sisters arrive

The Holy Cross Sisters had first arrived here from their convent in Notre Dame, Indiana, six months earlier. Sister Raymond (Mary) Sullivan and Sister Augusta (Amanda) Anderson traveled to Salt Lake City via train and stagecoach at the invitation of Father Lawrence Scanlan (soon to be Utah’s bishop), and more followed.

Scanlan hoped the nuns would help his fledgling Catholic community build schools and meet other human and spiritual needs. They did just that.

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A few years earlier, Sister Augusta had started her Holy Cross work as a Civil War nurse. She managed two Union army hospitals so well in the 1860s that Gen. Ulysses S. Grant exclaimed, “What a wonderful woman she is. She can control the men better than I can.”

Utah bard Gerald (Gary) McDonough’s aunt was a Holy Cross Sister, too, but a few years later. In his poem “Porch Nuns,” McDonough colorfully described the long black Holy Cross robes, also donned by pioneers like Sister Augusta.

Calling their veils “corrugated halos that circled their heads, Like broad white-walled tires,” he explained that whenever they visited his family, intrigued Latter-day Saint neighbors would emerge to watch “the giant emperor penguins, milling about the McDonoughs’ front porch.”

One can only imagine how unusual it was for the Salt Lake City Latter-day Saints to see those “giant emperor penguins” milling about downtown for the first time during the Christmas season of 1875.

That December, the women of St. Mary Magdalene church organized a fair to raise money for the new Holy Cross Hospital. A large crowd — including Catholics and Latter-day Saints — attended.

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The Tribune called it the “greatest attraction of the season,” one with music, plays, shooting galleries, “richly furnished refreshment tables,” and a “magnificent display of skillfully and delicately wrought fancy articles” for sale.

‘The Tennesseans’ perform

(Wikimedia Commons) Tennesseans concert poster shows Donavin’s original Tennessean slave cabin singers.

During the same week the grand fair was open, a popular singing group called “the Tennesseans” was in town as part of a national tour.

Contemporary newspaper articles and advertisements described the Tennesseans as “slave cabin singers” who performed “old plantation melodies and camp meeting hymns” from the South. These college students who once were slaves earned rave reviews wherever they sang.

After watching them perform, The Tribune said the widespread praise for the Tennesseans was well deserved. The Utah Evening Mail proclaimed them better than “any singers that have visited Salt Lake,” and the Deseret News called them the “most superb colored company in America.”

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(The Salt Lake Tribune) December 1875 Tribune ad for the Tennesseans’ December 1875 concerts in Salt Lake City.

One evening just before Christmas, right after the Tennesseans had finished a concert at the old Salt Lake Theatre, they stopped by the fair. To the crowd’s delight, they sang a couple of songs.

And then they did something that made the Christmas of 1875 one of the most memorable in Utah history. The former slaves serenaded the Holy Cross Sisters.

The Tribune reported that the Tennesseans sang some of “their finest melodies” to honor “Mother Augusta for her services in checking the Negro massacre at Fort Pillow during the war.” The Utah Evening Mail called the impromptu concert “an expression of gratitude” to the Holy Cross Sisters whose “humane services in aiding to suppress the Fort Pillow massacre” and whose “uniform devotion to the relief of the soldiers” would never be forgotten.

About the massacre

(Wikimedia Commons) A hand-colored 1892 print of the Battle of Fort Pillow by Kurz and Allison, a well-known Chicago firm specializing in colorful and dramatic chromolithograph prints of American historical events. The original is in the Library of Congress.

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In April 1864, Confederates massacred hundreds of Black Union soldiers stationed at a fortress the rebels had conquered in Tennessee. Sister Augusta cared for the surviving Fort Pillow victims at a nearby hospital she supervised.

It was difficult work.

Sister Augusta’s journal describes the appalling conditions of that hospital when she arrived: “Although we were tired and sick for want of sleep, there was no rest for us. We pinned up our habits, got brooms and buckets of water, and washed the bloodstained walls and scrubbed the floors. … The hospital was full of sick and wounded, but after some days, we succeeded in getting it comparatively clean.”

Notre Dame President Father William Corby — the chaplain of the Irish Brigade that famously fought at the Battle of Gettysburg — noted the full measure of Sister Augusta’s devotion: “The labors and self-sacrifices of the [Holy Cross] Sisters during the war need no praise here. Their praise is on the lips of every surviving soldier who experienced their kind and careful administrations.”

The grateful Tennesseans also remembered and thanked the Holy Cross Sisters with the gift of music. I cannot say for certain just what they sang 150 years ago in Salt Lake City during that most unusual Christmas of 1875. But I like to think that as the stars and the moon bathed the Wasatch foothills with a soft white light, the lovely lyrics of one song in particular — an old spiritual also born on a Southern plantation — rose gently into the crisp winter air and echoed off the snow-covered Oquirrh slopes, perhaps for the first time:

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When I was a seeker,

I sought both night and day.

I asked the Lord to help me,

And he showed me the way.

Go tell it on the mountain,

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Over the hills and everywhere,

Go tell it on the mountain,

That Jesus Christ is born!

(Courtesy photo)
Writer and attorney Michael Patrick O’Brien.

Note to readers Michael Patrick O’Brien is a writer and attorney living in Salt Lake City who frequently represents The Salt Lake Tribune in legal matters. His book “Monastery Mornings: My Unusual Boyhood Among the Saints and Monks,” was chosen by the League of Utah Writers as the best nonfiction book in 2022. His new holiday novel, tentatively titled “The Merry Matchmaker Monks of Shamrock Valley,” will be published in time for Christmas 2026. He blogs at theboymonk.com.

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Utah repeals ban on collective bargaining for teachers, firefighters, police unions

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Utah repeals ban on collective bargaining for teachers, firefighters, police unions


SALT LAKE CITY — Utah has repealed a collective bargaining ban passed earlier this year that prevented labor unions serving teachers, firefighters, police and other public employees from negotiating on behalf of their workers.

Republican Gov. Spencer Cox on Thursday approved the repeal of a policy that experts had called one of the most restrictive labor laws in the country.

The state’s Republican-controlled Legislature originally approved the policy in February, saying it was needed to allow employers to engage directly with all employees, instead of communicating through a union representative. Thousands of union members from the public and private sector rallied outside Cox’s office for a week, urging him to veto the bill, which he decided to sign.

Pushback continued in the months after it became law, with the Legislature ultimately deciding on a reversal during a special session this month.

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Republican state Rep. Jordan Teuscher, the original House sponsor, said the repeal “allows us to step back, to lower the temperature and to create space for a clearer and more constructive conversation.”

He maintained that it was a “good policy” that has been “overshadowed by misinformation and unnecessary division.”

The decision comes as Utah Republicans are preparing to defend their four U.S. House seats in the 2026 midterm elections under a new congressional map that creates a heavily Democratic-leaning district in the Salt Lake City area.

A repeal helps Republicans appease the many police officers and firefighters — groups that often lean conservative — who were frustrated by the ban.

State employees were still allowed to join unions under the law, but the unions could not formally negotiate on their behalf for better wages and working conditions.

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Many public educators, the state’s most frequent users of collective bargaining, viewed the policy as way for Republicans to weaken teachers unions and clear a path for their own education agenda.

Teachers unions have been outspoken opponents of Republican policies in Utah and other states where lawmakers have sought to eliminate diversity, equity and inclusion programs, expand school choice vouchers and restrict transgender bathroom use and sports participation in schools.

Union leaders celebrated the repeal and the work of their members who rallied opposition to the law.

Randi Weingarten, president of the American Federation of Teachers, and Brad Asay, the Utah chapter leader, called the repeal “a historic step in the right direction to return respect and dignity to the workers of Utah.”



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Utah hit with largest measles outbreak in over 30 years

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Utah hit with largest measles outbreak in over 30 years


Utah has been hit with the largest measles outbreak in more than 30 years.

The Utah State Epidemiologist stated that it’s the most contagious disease scientists know of.

As of this month, the Utah Department of Health and Human Services reported 115 confirmed cases.

MORE | Measles

“It’s a little surprising to see an uptick in measles, but it’s not surprising to hear that Utah County is one of the places where we have seen more of those cases,” said Elsie, a Utah County resident with several children in local schools. “I think because there’s kind of been a movement towards anti-vaccination.”

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Samantha Marberger, who also lives in Utah County and has a young child, said measles wasn’t something she thought was here.

“I’ve heard of big outbreaks like that in Texas and a few other places, but it wasn’t something that I thought was as local,” she said.

Utah State Epidemiologist Leisha Nolen called the outbreak “extreme” and “really concerning.”

“Why does the health department believe this is happening now? Is this like a delayed reaction of previous low vaccination rates?” 2News asked her.

“Yeah, I think unfortunately our vaccine rates have gone down over time, and we do now have a number of people who are vulnerable to this infection, and they haven’t been protected,” Nolen said. “There also has been cases in neighboring states, and so it was easy to introduce here in Utah.”

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The DHHS stated that roughly 90% of the population is vaccinated, but those rates vary from area to area and aren’t enough to reach herd immunity for measles.

“Measles is highly contagious. It’s the most contagious infection we know of,” Nolen said. “The data historically says that if you have 20 people in a room and somebody with measles comes in, 18 of those people are going to get measles.”

She said that since the outbreak started, the health department has given 30% more vaccines than they did last year at this time. She said most infections can be traced back to southwestern Utah and appear to be from in-state travel.

“It’s likely in Utah, many hundreds of Utahns who are vaccinated have been exposed to this virus, and they did not know it, and their bodies fought it off as it should,” Nolen said.

The second largest outbreak in Utah is in Utah County, with 10 confirmed cases.

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The state is asking people to cooperate with the health department’s contact tracers if they call.

If you suspect measles in yourself or a loved one, they urge you not to go to a clinic waiting room but call ahead for the next steps to stop the spread.

_____



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