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Why the CDC is inviting travelers from China to swab their noses at LAX

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Why the CDC is inviting travelers from China to swab their noses at LAX

LAX’s arrivals space within the Tom Bradley Worldwide Terminal is now filling with the sounds of Mandarin, Cantonese, Hunanese and different languages as vacationers from China seize the possibility to enter america for the primary time in almost three years.

Beneath a brand new coverage from the Facilities for Illness Management and Prevention, all have been required to supply a unfavorable COVID-19 check earlier than boarding their flights to america. However that’s an imperfect technique of safety, proven to overlook wherever from 30% to 70% of people who find themselves within the early levels of an an infection.

The sudden return of Chinese language guests could inadvertently throw a little bit of gas onto the dumpster fireplace of COVID-19 instances that continues to burn in america. However the CDC can also be involved a couple of extra distant — and much scarier — risk: {that a} traveler from China contaminated with a brand new coronavirus variant might enter the nation and jump-start a recent wave of transmission and sickness.

“New variants can come up wherever there’s uncontrolled an infection, and COVID is spreading via China like wildfire,” mentioned Harvard College infectious illness specialist Dr. Jonathan Li.

The Omicron variant appears to have triumphed over all different variations of the SARS-CoV-2 virus, Li famous. However sufferers with weakened immune techniques stay the most certainly incubators of latest variants, “and I’ve little question absolutely the variety of immunosuppressed sufferers in China is in depth,” he mentioned.

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As for whether or not these circumstances spawn new variations of the pandemic virus and the way far they may journey, “we’ll need to see,” Li added.

That’s the mission of the Traveler Genomic Surveillance program, a virus-hunting initiative the CDC quietly stood up in September 2021. Its foot troopers have been deployed at LAX for the primary time on Tuesday morning.

With smiles evident behind face masks and thank-you items in hand, these sentinels in plain black scrubs are tasked with in search of volunteers whose flights originated in China who’re keen to swab their noses to help the seek for new viral variants. Those that agree will obtain a free take-home COVID-19 check as a token of America’s appreciation.

Whereas new to LAX, the CDC program already operates in worldwide airports in San Francisco, Seattle, New York Metropolis, Newark, N.J., Washington, D.C., and Atlanta. Over the previous 15 months, it has persuaded about 80,000 vacationers from each nook of the world to take part.

Well being officers hope the brand new testing website at LAX will assist them determine new coronavirus variants that could be brewing in China.

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(Gary Coronado/Los Angeles Occasions)

Offering U.S. well being officers with an early warning of latest variants is one goal of the CDC’s public-private partnership with Ginkgo Bioworks, a medical testing firm, and XpresCheck, which grew out of a spa-services firm providing massages, mani-pedis and wellness merchandise in a dozen U.S. airports.

The opposite key goal is to fill within the absent or incomplete photos of SARS-CoV-2 variants circulating in international locations the place genetic sequencing is both not being carried out or not being shared with the worldwide group.

China is a type of worldwide blind spots. Because the pandemic has progressed and the federal government carried out billions of coronavirus exams as a part of its “zero COVID” coverage, its scientists have shared solely a handful of genetic sequences with their counterparts abroad.

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“There’s been little or no information from China” uploaded to internationally obtainable websites, mentioned Dr. Cindy Friedman, chief of the CDC’s Vacationers’ Well being Department. “That’s why vacationers as sentinels are so invaluable.”

A central function of this system is what it does not do: observe or observe volunteers who, regardless of testing necessities, may arrive in america contaminated.

Even within the unlikely occasion that a global traveler is discovered to hold a brand new genetic variant, the CDC could be unable to make use of that volunteer’s pattern to trace her or him down.

“That is certainly not a border-control program designed to search out and isolate” people, Friedman mentioned. “It is a surveillance program” aimed toward offering early warning of an impending risk.

That is without doubt one of the causes this system just isn’t carried out by CDC workers, who preserve a presence at worldwide airports to man “quarantine stations.” As a substitute, workers of XpresCheck await the arrival of particular flights and strategy potential volunteers outdoors of immigration and customs areas.

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Till not too long ago, they’ve been wearing orange scrubs and led keen vacationers to vivid orange cubicles bearing logos of the CDC, XpresCheck and Ginkgo Bioworks. The change to black scrubs is new with the growth to LAX.

“We don’t need individuals to assume it is a obligatory program,” mentioned Ezra Ernst, president and CEO of ExpresTest Inc., which, with XpresSpa and XpresCheck, operates beneath the company banner of Xwell. “’Would you assist?’ is a phrase we use typically.”

Claire Altieri works with colleagues Ryan Kramer and Amy Schierhorn to set up the new  coronavirus testing site at LAX.

Claire Altieri (seated) works with colleagues Ryan Kramer and Amy Schierhorn to arrange the brand new coronavirus testing website at LAX’s Tom Bradley Worldwide Terminal. Employees started asking volunteers to supply samples on Tuesday.

(Gary Coronado/Los Angeles Occasions)

As soon as a keen traveler swabs her nostril and solutions some questions on her place to begin and path to america, her specimen is blended with 4 others to create a “pooled pattern” for inexpensive and extra environment friendly testing by Ginkgo Bioworks labs throughout the nation. If a pooled pattern comes up optimistic, staff can genetically sequence every of the specimens that have been grouped collectively to determine the one with uncommon genetic traits.

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If the surveillance program detects a brand new coronavirus variant, “we will purchase science weeks and months of realizing what’s coming,” Friedman mentioned. “That buys time to know the variant, and what changes must be made,” she added.

Through the preliminary weeks of the Omicron surge, this system was the primary to choose up on two subvariants that got here to be often known as BA.2 and BA.3. The CDC reported them to the worldwide database maintained by the GISAID Initiative, permitting scientists to shortly assess whether or not and the way their novel mutations affected their transmissibility, their skill to sicken, and their skill to beat vaccine safety.

This system’s subsequent transfer could take it from airport arrivals terminals to the plane bathrooms. Friedman mentioned the CDC hopes to persuade business airways to permit the gathering of wastewater from bathrooms on long-distance worldwide flights so it may be used for sampling and genetic sequencing.

“On a long-haul flight, all people makes use of the lavatory,” Friedman mentioned. Even when vacationers decline to volunteer at airports, wastewater surveillance from plane “offers you an image” of what passengers could carry into america, she mentioned.

Researchers in Australia partnered with Qantas Airways to evaluate the feasibility of plane wastewater testing and concluded it might be an “efficient device” for “monitoring the importation of SARS CoV-2 and different clinically vital pathogens.”

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Rolling it out on a big scare poses authorized, moral and technical challenges for airways, which haven’t but signed on. However “that’s the imaginative and prescient going ahead,” mentioned Friedman, who expressed optimism that business carriers “could be nice companions.”

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A champion of psychedelics who includes a dose of skepticism

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A champion of psychedelics who includes a dose of skepticism

Book Review

Trippy: The Peril and Promise of Medicinal Psychedelics

By Ernesto Londoño
Celadon Books: 320 pages, $29.99
If you buy books linked on our site, The Times may earn a commission from Bookshop.org, whose fees support independent bookstores.

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Ernesto Londoño’s engrossing and unsettling new book, “Trippy: The Peril and Promise of Medicinal Psychedelics,” is part memoir, part work of journalism. It tells of how Londoño sought relief from depression with mind-altering drugs. It also investigates the current fad of “medicinal” psychedelics as a treatment for those struggling with depression, trauma, suicidality and other conditions.

Like other psychedelic enthusiasts, Londoño — a journalist who reported in conflict zones such as Iraq and Afghanistan and served as the New York Times’ Brazil bureau chief — wants us to like psychedelics. They relieve him of depression and suicidality. He then continues to “trip” to engage in self-exploration: escape reality, journey into himself and return with an expanded view of the world.

Calling street drugs and hallucinogenics such as psilocybin, MDMA/ecstasy, LSD and ayahuasca “medicine” is problematic. Psychedelic psychiatry has had a resurgence in the past decade, though only among a minority of medical professionals. Mainstream psychiatry largely abandoned psychedelics by the 1970s, for a variety of reasons.

The renewed interest in psychedelics as a treatment seems to arise more from hope than science — a wish that medicinal psychedelics will be effective because our current treatments are inadequate. Antidepressants known as SSRIs and other approaches are often ineffectual, but that doesn’t mean psychedelics, which can be damaging to many in acute distress, should be tried.

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Londoño is more balanced in discussing the benefits and dangers than Michael Pollan and others. Pollan’s bestselling book-turned-Netflix-series “How to Change Your Mind” proselytizes medicinal psychedelics in a way that “Trippy” thankfully doesn’t.

Londoño brings a healthy dose of skepticism. Psychedelics aren’t romanticized with examples of the counterculture movement of the 1960s or hyped by listing celebrities currently using them. The author often questions how much of what he’s part of is “a cult” and if what he’s taking is “voodoo,” not medicine.

Ernesto Londoño, author of "Trippy"

Ernesto Londoño, author of “Trippy.”

(Jenn Ackerman)

“Trippy” is a fascinating account of the world of medicinal psychedelics. We attend psychedelic retreats in the Amazon and Latin America. We drink ayahuasca, a syrupy, foul-tasting psychoactive tea that induces vomiting and hallucinations. Ayahuasca calls back “memories” — some real, others false — that participants take as the cause of their emotional ill health.

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We visit a ketamine clinic, where Londoño feels a “blissful withdrawal,” retaining “strong powers of perception” but losing “any sense of being a body with limbs that can move at will.”

We watch MDMA (a German pharmaceutical from 1912 now best known as the street drug called ecstasy or molly) being administered at a veterans hospital to treat post-traumatic stress disorder. At a “treatment center”/church/spiritual refuge in Austin, Texas, we witness tobacco being blown into a man’s nostrils, extract from an Amazonian plant squirted into his eyes, and toad venom burned into his forearms under the guise of spiritual salvation.

Unlike the unbridled enthusiasts, Londoño exposes the predatory nature of the psychedelic industry and how it exoticizes the use of hallucinogens as Indigenous medicines. We’re privy to some scandals in this field, specifically sexual abuse and harassment and taking advantage of vulnerable people looking for help.

It’s an engaging memoir of one man’s experiences with psychedelics. Londoño’s little asides, like when he’s talking about meeting the man who would become his husband, endear him to us: “I saw the profile of a handsome man visiting from Minnesota for the weekend. He was a vegetarian and veterinarian. Swoon!”

But as a work of mental health journalism, “Trippy” isn’t, as the book jacket suggests, “the definitive book on psychedelics and mental health today.”

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Much is overlooked and left out. Londoño fails to stress that these treatments best serve the “worried well,” those struggling with relatively mild complaints, but can be extremely unsafe for those with serious mental illness, meaning severe dysfunction. Such a person has typically been diagnosed with bipolar disorder, major depressive disorder with suicidality, post-traumatic stress or schizophrenia. They can’t hold a job or live independently, often for years.

Most people Londoño interviews in “Trippy” seek “bliss,” not lifesaving measures to give them a chance at basic functioning. The retreats are less mental health centers than gatherings of spiritual seekers.

Full disclosure: I read “Trippy” with an open mind and as someone who spent 25 years in the American mental health system with serious mental illness. Those years passed the way they do for so many: a string of hospitalizations endured, countless therapeutic modalities tried, numerous mental health professionals seen and myriad psychiatric medications taken (yes, in the double digits).

“Medicinal” psychedelics never came up as a potential treatment. I recovered before fringe psychiatry’s renewed interest in psychedelics became a fad in the past decade.

It’s unsettling that Londoño doesn’t mention the recovery movement and what we know can lead to mental health recovery. He doesn’t mention the five Ps, which are based on the four Ps that Thomas Insel, former head of the National Institute of Mental Health, writes about in “Healing: Our Path from Mental Illness to Mental Health.” To heal, we need people (social support), place (a safe home), purpose (meaning in life), payment (access to mental health care) and physical health (a clean diet and, ironically, no drugs or alcohol).

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In this, Londoño fails to explore whether his recovery had as much to do with the changes he made as a result of his first treatment/trip as with psychedelics themselves: changes in diet, renewed purpose, finding love, moving into a new home, leaving his stressful job. If two centuries of psychiatric research has taught us one thing, it’s that there is no magic bullet for mental health recovery.

The book’s most compelling explorations into psychedelics as mental health treatments come when Londoño discusses their use in treating trauma, particularly that which war journalists and veterans experience.

He also explores the pervasiveness of mental health issues and the particular challenges LGBTQ+ people can face.

“Trippy” raises seminal questions we need to be asking as the psychedelic industry reaches further into mental health treatment:

What is “medicine” and what is an illicit drug?

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Are we trying to treat those in crisis or simply help anyone escape the suffering that’s part of the human experience?

Should we continue to try more and more extreme treatments?

Or should we finally pay attention to and change systemic issues that are the root cause of so much mental and emotional distress?

Sarah Fay is the author of the bestselling memoirs “Pathological: The True Story of Six Misdiagnoses” and “Cured.”

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Maps of Two Cicada Broods, Reunited After 221 Years

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Maps of Two Cicada Broods, Reunited After 221 Years

This spring, two broods of cicadas will emerge in the Midwest and the Southeast, in their first dual appearance since 1803.

A cicada lays eggs in an apple twig.

“Insects: Their Ways and Means of Living,” by Robert E. Snodgrass, 1930, via the Biodiversity Heritage Library

Brood XIII, the Northern Illinois Brood, hatched and burrowed into the ground 17 years ago, in 2007.

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Brood XIX, the Great Southern Brood, hatched in 2011 and has spent 13 years underground, sipping sap from tree roots.

The entomologist Charles L. Marlatt published a detailed map of Brood XIX, the largest of the 13-year cicada broods, in 1907.

Historic map of cicada emergence.

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He also mapped the expected emergence of Brood XIII in 1922.

Historic map of cicada emergence.

This spring the two broods will surface together, and are expected to cover a similar range.

Modern map of cicada emergence.

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Up to a trillion cicadas will rise from the warming ground to molt, sing, mate, lay eggs and die.

A Name and a Number

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Charles L. Marlatt proposed using Roman numerals to identify the regional groups of 13- and 17-year periodical cicadas, beginning with Brood I in 1893.

A brood can include up to three or four cicada species, all emerging at the same time and singing different songs. Long cicada lifespans of 13 or 17 years spent underground have spawned many theories, and may have evolved to reduce the likelihood of different broods surfacing at the same time.

Large broods might sprawl across a dozen or more states, while a small brood might only span a few counties. Brood VII is the smallest, limited to a small part of New York State and at risk of disappearing.

At least two named broods are thought to have vanished: Brood XXI was last seen in 1870, and Brood XI in 1954.

Not Since the Louisiana Purchase

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Brood XIII and Brood XIX will emerge together this year, for the first time in more than two centuries. But only in small patches of Illinois are they likely to come out of the ground in the same place.

In 1786 and 1790, the two broods burrowed into Native lands, divided by the Mississippi River into nominally Spanish territory and the new nation of the United States.

An historic map of the United States from 1783.

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Brood XIII entered the ground in 1786, and Brood XIX in 1790. (Expected 2024 ranges are overlaid on the map.)

An historic map of the United States from 1783.

As the ground was warming in April 1803, France sold the rights to the territory of Louisiana, which it acquired from Spain in 1800, to the United States for $15 million.

An historic map of the United States from 1801.

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That spring, Brood XIII and Brood XIX emerged together into a newly enlarged United States.

An historic map of the United States from 1803.

Their descendants — 13 and 17 generations later — are now poised to return, and will not sing together again until 2245.

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An historic map of the United States from 1868.

A ‘Great Visitation’

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After an emergence of Brood X cicadas in 1919, the naturalist Harry A. Allard wrote:

Although the incessant concerts of the periodical cicadas persisting from morning until night became almost disquieting at times, I felt a positive sadness when I realized that the great visitation was over, and there was silence in the world again, and all were dead that had so recently lived and filled the world with noise and movement.

It was almost a painful silence, and I could not but feel that I had lived to witness one of the great events of existence, comparable to the occurrence of a notable eclipse or the invasion of a great comet.

Then again the event marked a definite period in my life, and I could not but wonder how changed would be my surroundings, my experiences, my attitude toward life, should I live to see them occur again seventeen years later.

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The transformation of a cicada nymph (1), into an adult (10).

“The Periodical Cicada,” by Charles L. Marlatt, 1907, via the Biodiversity Heritage Library

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What are the blue blobs washing up on SoCal beaches? Welcome to Velella velella Valhalla

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What are the blue blobs washing up on SoCal beaches? Welcome to Velella velella Valhalla

The corpses are washing up by the thousands on Southern California’s beaches: a transparent ringed oval like a giant thumbprint 2 to 3 inches long, with a sail-like fin running diagonally down the length of the body.

Those only recently stranded from the sea still have their rich, cobalt-blue color, a pigment that provides both camouflage and protection from the sun’s UV rays during their life on the open ocean.

Aggressive and impactful reporting on climate change, the environment, health and science.

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These intriguing creatures are Velella velella, known also as by-the-wind sailors or, in marine biology circles, “the zooplankton so nice they named it twice,” said Anya Stajner, a biological oceanography PhD student at UC San Diego’s Scripps Institution of Oceanography.

A jellyfish relative that spends the vast majority of its life on the surface of the open sea, velella move at the mercy of the wind, drifting over the ocean with no means of locomotion other than the sails atop their bodies. They tend to wash up on the U.S. West Coast in the spring, when wind conditions beach them onshore.

Springtime velella sightings documented on community science platforms like iNaturalist spiked both this year and last, though scientists say it’s too early to know if this indicates a rise in the animal’s actual numbers.

Velella are an elusive species whose vast habitat and unusual life cycle make them difficult to study. Though they were documented for the first time in 1758, we still don’t know exactly what their range is or how long they live.

These beaching events confront us with a little-understood but essential facet of marine ecology — and may become more common as the oceans warm.

“Zooplankton” — the tiny creatures at the base of the marine food chain — “are sort of this invisible group of animals in the ocean,” Stajner said. “Nobody really knows anything about them. No one really cares about them. But then during these mass Velella velella strandings, all of a sudden there’s this link to this hidden part of the ocean that most of us don’t get to experience.”

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What looks like an individual Velella velella is actually a colony of teeny multicellular animals, or zooids, each with their own function, that come together to make a single organism. They’re carnivorous creatures that use stinging tentacles hanging below the surface to catch prey such as copepods, fish eggs, larval fish and smaller plankton.

Unlike their fellow hydrozoa, the Portuguese man o’ war, the toxin in their tentacles isn’t strong enough to injure humans. Nevertheless, “I wouldn’t encourage anyone to touch their mouth or their eyes after they pick one up on the beach,” said Nate Jaros, senior director of fishes and invertebrates at the Aquarium of the Pacific in Long Beach.

Velella that end their lives on California beaches typically have sails that run diagonally from left to right along the length of their bodies, an orientation that catches the onshore winds heading in this direction. As the organism’s carcass dries in the sun and the soft tissues decay, the blue color disappears, leaving the transparent chitinous float behind.

“The wind really just brings them to our doorstep in the right conditions,” Jaros said. “But they’re designed as open ocean animals. They’re not designed to interact with the shoreline, which is usually why they meet their demise when they come into contact with the shore.”

1

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Velella velella seen under a microscope

2 Magnified Velella velella samples

3 Close-up image of Velella velella, showing tentacles and blue, green and brown hues

1. Anya Stajner put Velella velella under a microscope. 2. Magnified, you can see more than blue in the organism. “That green and brown coloration comes from their algae symbionts,” Stajner said. 3. Notice the tentacles too. (Anya Stajner)

Velella show up en masse when two key factors coincide, Stajner said: an upwelling of food-rich, colder water from deeper in the ocean, followed by shoreward winds and currents that direct the colonies to beaches.

A 2021 paper from researchers at the University of Washington found a third variable that appears to correlate with more velella sightings: unusually high sea surface temperatures.

After looking at data over a 20-year period, the researchers found that warmer-than-average winter sea surface temperatures followed by onshore winds tended to correlate with higher numbers of velella strandings the following spring, from Washington to Northern California.

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“The spring transition toward slightly more onshore winds happens every year, but the warmer winter conditions are episodic,” said co-author Julia K. Parrish, a University of Washington biologist who runs the Coastal Observation and Seabird Survey Team community science project.

Given that sea surface temperatures have been consistently above the historical average every day since March 2023, the current velella bloom is consistent with those findings.

Previous research has found that gelatinous zooplankton like velella and their fellow jellyfish thrive in warmer waters, portending an era some scientists have referred to as the “rise of slime.”

Other winners of a slimy new epoch would be ocean sunfish, a giant bony fish whose individuals can clock in at more than 2,000 pounds and consume jellyfish — and velella — in mass quantities. Ocean sunfish sightings tend to rise when velella observations do, Jaros said.

“The ocean sunfish will actually kind of put their heads out of the water as they eat these. It resembles Pac-Man eating pellets,” he said. (KTLA-TV published a picture of just that this week.)

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Though velella blooms are ephemeral, we don’t yet know how long any individual colony lives. The blue seafaring colonies are themselves asexual, though they bud off tiny transparent medusas that are thought to go to the deep sea and reproduce sexually there, Stajner said. The fertilized egg then evolves into a float that returns to the surface and forms another colony.

A woman on a boat wearing a blue beanie and holding a Velella velella specimen

Anya Stajner, a PhD student at Scripps, collected by-the-wind sailors but was unable to keep them alive in a lab. “Rearing gelatinous organisms is pretty difficult,” she said.

“I was able to actually collect some of those medusae last year during the bloom, but rearing gelatinous organisms is pretty difficult,” Stajner said. The organisms died in the lab.

Stajner left May 1 on an eight-day expedition to sample velella at multiple points along the Santa Lucia Bank and Escarpment in the Channel Islands, with the goal of getting “a better idea of their role in the local ecosystem and trying to understand what these big blooms mean,” she said.

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