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SoCal officials unleash sterile mosquitoes in bid to curb disease — with promising results

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SoCal officials unleash sterile mosquitoes in bid to curb disease — with promising results

A battle is underway against an invasive mosquito behind a recent surge in the local spread of dengue fever in Southern California — and officials may have unlocked a powerful tool to help win the day.

Two vector control districts — local agencies tasked with controlling disease-spreading organisms — released thousands of sterile male mosquitoes in select neighborhoods, with one district starting in 2023 and the other beginning the following year.

The idea was to drive down the mosquito population because eggs produced by a female after a romp with a sterile male don’t hatch. And only female mosquitoes bite, so unleashing males doesn’t lead to transmission of diseases such as dengue, a potentially fatal viral infection.

The data so far are encouraging.

One agency serving a large swath of Los Angeles County found a nearly 82% reduction in its invasive Aedes aegypti mosquito population in its release area in Sunland-Tujunga last year compared with a control area.

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Another district, covering the southwestern corner of San Bernardino County, logged an average decrease of 44% across several heavily infested places where it unleashed the sterile males last year, compared with pre-intervention levels.

Overall invasive mosquito counts dropped 33% across the district — marking the first time in roughly eight years that the population went down instead of up.

“Not only were we out in the field and actually seeing good reductions, but we were getting a lot less calls — people calling in to complain,” said Brian Reisinger, community outreach coordinator for the Inland Empire’s West Valley Mosquito and Vector Control District.

But challenges remain. Scaling the intervention to the level needed to make a dent in the vast region served by the L.A. County district won’t happen overnight and would potentially require its homeowners to pay up to $20 in an annual property tax assessment to make it happen.

Climate change is allowing Aedes mosquitoes — and diseases they spread — to move into new areas and go gangbusters in places where they’re established.

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Surging dengue abroad and the widespread presence of Aedes mosquitoes at home is “creating this perfect recipe for local transmission in our region,” said Dr. Aiman Halai, director of the vector-borne disease unit at the L.A. County Department of Public Health.

Tiny scourge, big threat

Aedes aegypti mosquitoes were first detected in California about a decade ago. Originally hailing from Africa, the species can transmit dengue, as well as yellow fever, Zika and chikungunya.

Another invasive mosquito, Aedes albopictus, arrived earlier, but its numbers have declined and it is less likely to spread diseases such as dengue.

Although the black-and-white striped Aedes aegypti can’t fly far — just about 150 to 200 yards — they manage to get around. The low-flying, day-biting mosquitoes are present in more than a third of California’s counties, including Shasta County in the far north.

An Aedes mosquito, known for nipping ankles, prefers to bite humans over animals. The insects, which arrived in California about a decade ago, can transmit diseases such as dengue and Zika.

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(Orange County Mosquito and Vector Control District)

Aedes mosquitoes love to bite people — often multiple times in rapid succession. As the insects spread across the state, patios and backyards morphed from respites into risky territories.

But tamping down the bugs has proved difficult. They can lay their eggs in tiny water sources. And they might lay a few in a plant tray and others, perhaps, in a drain. Annihilating invaders isn’t easy when it can be hard to locate all the reproduction spots — or access all the yards where breeding is rampant.

That’s one of the reasons why releasing sterilized males is attractive: They’re naturally adept at finding their own kind.

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Mosquito vs. mosquito

Releasing sterilized male insects to combat pests is a proven scientific technique that’s been around since the 1950s, but using it to control invasive mosquitoes is relatively new. The approach appears to be catching on in Southern California.

The West Valley district pioneered the release of sterilized male mosquitoes in California. In 2023, the Ontario-based agency rolled out a pilot program before expanding it the following year. This year it is increasing the number of sites being treated.

The Greater Los Angeles County Vector Control District launched its own pilot effort in 2024 and plans to target roughly the same area this year — with some improvements in technique and insect-rearing capacity.

Starting in late May, an Orange County district will follow suit with the planned release of 100,000 to 200,000 sterile male mosquitoes a week in Mission Viejo through November. A Coachella Valley district is plugging away at developing its own program, which could get off the ground next spring.

Vector officials in L.A. and San Bernardino counties said residents are asking them when they can bring a batch of zapped males to their neighborhood. But experts say for large population centers, it’s not that easy.

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“I just responded this morning to one of our residents that says, ‘Why can’t we have this everywhere this year?’ And it’s, of course, because Rome wasn’t built in a day,” said Susanne Kluh, general manager for the Greater Los Angeles County Vector Control District.

Kluh’s district has a budget of nearly $24 million and is responsible for nearly 6 million residents across 36 cities and unincorporated areas. West Valley’s budget this fiscal year is roughly $4 million, and the district serves roughly 650,000 people in six cities and surrounding county areas.

Approaches between the two districts differ, in part due to the scale they’re working with.

West Valley targets what it calls hot spots — areas with particularly high mosquito counts. Last year, before peak mosquito season, it released about 1,000 sterile males biweekly per site. Then the district bumped it to up to 3,000 for certain sites for the peak period, which runs from August to November. The idea is to outnumber wild males by 100 to 1. Equipment for the program cost about $200,000 and the district hired a full-time staffer to assist with the efforts this year for $65,000.

Solomon Birhanie, scientific director for West Valley, said the district doesn’t have the resources to attack large tracts of land so it’s using the resources it does have efficiently. Focusing on problem sites has shown to be sufficient to affect the whole service area, he said.

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“Many medium to smaller districts are now interested to use our approach,” he said, because there’s now evidence that it can be incorporated into abatement programs “without the need for hiring highly skilled personnel or demanding a larger amount of budget.”

A man in a white lab coat, wearing black gloves, holds a syringe over a plastic container

Solomon Birhanie, scientific director at the West Valley Mosquito and Vector Control District, views a container of mosquito larvae in the lab in March 2024. The Ontario-based district pioneered the release of sterilized male Aedes mosquitoes in California.

(Allen J. Schaben / Los Angeles Times)

In its inaugural study last year, the L.A. County district unleashed an average of 30,000 males per week in two Sunland-Tujunga neighborhoods between May and October — seeking to outperform wild males 10 to 1. Kluh anticipates this year’s pilot will cost about $350,000.

In order to bring the program to a larger area of the district, Kluh said more funding is needed — with officials proposing up to $20 annually per single-family home. That would be in addition to the $18.97 district homeowners now pay for the services the agency already provides.

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If surveys sent to a sample of property owners favor the new charge, it’ll go to a vote in the fall, as required by Proposition 218, Kluh said.

There are five vector control districts that cover L.A. County. The Greater L.A. County district is the largest, stretching from San Pedro to Santa Clarita. It covers most of L.A. city except for coastal regions and doesn’t serve the San Gabriel or Antelope valleys.

Galvanized by disease

California last year had 18 locally acquired dengue cases, meaning people were infected with the viral disease in their communities, not while traveling.

Fourteen of those cases were in Los Angeles County, including at least seven tied to a small outbreak in Baldwin Park, a city east of L.A. Cases also cropped up in Panorama City, El Monte and the Hollywood Hills.

The year before that, the state confirmed its first locally acquired cases, in Long Beach and Pasadena.

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Although most people with dengue have no symptoms, it can cause severe body aches and fever and, in rare cases, death. Its alias, “breakbone fever,” provides a grim glimpse into what it can feel like.

Over a third of L.A. County’s dengue cases last year required hospitalization, according to Halai.

Mosquitoes pick up the virus after they bite an infected person, then spread it by biting others.

Hope and hard truths

Mosquito control experts tout sterilization for being environmentally friendly because it doesn’t involve spraying chemicals and officials could potentially use it to target other disease spreaders — such as the region’s native Culex mosquito, a carrier of the deadly West Nile virus.

New technologies continue to come online. In the summer last year, the California Department of Pesticide Regulation approved the use of male mosquitoes infected with a particular strain of a bacteria called Wolbachia. Eggs fertilized by those males also don’t hatch.

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Despite the promising innovations, some aspects of the scourge defy local control.

Since her start in mosquito control in California nearly 26 years ago, Kluh said, the season for the insects has lengthened as winters have become shorter. Back then, officials would get to work in late April or early May and wrap up around early October. Now the native mosquitoes emerge as early as March and the invasive insects can stick around into December.

“If things are going the way it is going now, we could just always have some dengue circulating,” she said.

Last year marked the worst year on record for dengue globally, with more than 13 million cases reported in the Americas and the Caribbean, according to the Centers for Disease Control.

Many countries are still reporting higher-than-average dengue numbers, meaning there’s more opportunity for travelers to bring it home.

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Pace of N.I.H. Funding Slows Further in Trump’s Second Year

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Pace of N.I.H. Funding Slows Further in Trump’s Second Year

Spending on new medical research by the National Institutes of Health has fallen roughly $1 billion behind the pace of years past, delaying thousands of scientific projects and raising concerns within the agency that it may struggle to pay out the money it was allotted by Congress.

Instead of canceling grants en masse, as the N.I.H. did in the first year of this Trump presidency, it is now vetting them before approval with a “computational text analysis tool” that scans for terms including “racism,” “gender” and “vaccination refusal,” according to documents obtained by The New York Times.

That tool was meant to formalize a campaign against “woke science” that was initiated last year by the Elon Musk-led Department of Government Efficiency.

But the screening system is now exacerbating a slowdown in research spending: The N.I.H. awarded only about 1,900 new and competitive grants from October to late March, less than half the number it tended to give out by that point in the fiscal year during the Biden administration, an analysis by The Times showed.

The heaviest damage to the grantmaking apparatus was done by the protracted government shutdown in the fall, which delayed grant review meetings by months. The N.I.H. has struggled to catch up, and delays are affecting fields far beyond those ostensibly targeted by the administration’s crusade against diversity, equity and inclusion.

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As of late March, for example, the National Cancer Institute had earmarked only about $72 million for new and competitive research grants, less than one-third of the nearly $250 million it had agreed to spend by that point in a typical fiscal year during the Biden administration, according to The Times’s analysis.

“It means that people get fired because there is uncertainty about whether the grant will come through,” said Dr. Joshua Gordon, a professor of psychiatry at Columbia University and a former director of the National Institute of Mental Health. “It means budgets get busted. It means research projects get stalled.”

However alarming the canceled grants and spending delays were last year, Dr. Gordon said, “I’m more worried this year.”

The Department of Health and Human Services, which oversees the N.I.H. and is led by Secretary Robert F. Kennedy Jr., has become involved this year in flagging certain grant awards and stopping their release, according to emails reviewed by The Times.

Mr. Kennedy faced sharp criticism from Democratic and Republican lawmakers alike over N.I.H. spending delays in congressional hearings this week. He is set to appear at two more hearings on Wednesday.

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The N.I.H. has fallen behind in part because it lost thousands of workers last year to layoffs and early retirements. In some branches of the agency, what workers remain can barely keep up with renewing existing grants, much less awarding new ones.

One N.I.H. institute has less than half of the workers needed to vet grants for legal and financial compliance, employees were told at a recent meeting, notes from which were reviewed by The Times.

Under the most dire projections, the institute could leave $500 million of congressionally appropriated funding on the table because of difficulties processing grants, N.I.H. officials said at that meeting. They were temporarily deploying career scientists to what were effectively business roles to speed up grant awards.

The N.I.H. director, Dr. Jay Bhattacharya, has said that he is trying to root out ideologically motivated and insufficiently rigorous science. Conservatives accuse the N.I.H. of having fostered such research during the Obama and Biden presidencies by, for example, encouraging grant proposals on sexual- and gender-minority groups.

“Scientists will no longer have to mouth D.E.I. shibboleths to garner funding,” Dr. Bhattacharya and his top deputy wrote in an online article in December, the day before the N.I.H. outlined the new screening process to its employees.

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Andrew Nixon, a health department spokesman, blamed the spending shortfall on “the Democrat-led shutdown,” which he said “delayed N.I.H.’s ability to issue grants” at the start of the fiscal year. Since then, he said, “timelines have returned to typical funding patterns.”

He added that the agency “uses a variety of review tools to ensure alignment with agency priorities” and that it was working to hire additional employees. “The N.I.H. intends to obligate all appropriated funds, as directed by Congress,” he said.

To understand why spending has slowed so dramatically at the N.I.H., the world’s premier funder of medical research, The Times interviewed 10 agency employees and reviewed internal documents, including spreadsheets of grants flagged by the screening tool and the list of roughly 235 terms it searches for.

The employees spoke on the condition of anonymity because they were not authorized to comment publicly.

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The documents painted a picture of an agency whose leaders were seeking to exert greater control over scientific spending by, among other things, deciding whether certain grants were compatible with agency priorities. But in clamping down on the funding process, the N.I.H. created new choke points, leaving some proposals in limbo for days or weeks.

That has frustrated some senior N.I.H. officials, one of whom lamented in an email seen by The Times that it was taking too long to rework grant proposals. The official asked his staff to simply strip the proposals of disfavored terms instead.

The delays have also angered lawmakers. Congress sets the country’s medical research spending levels, even as the administration has leeway to prioritize types of studies. And despite Mr. Trump’s proposing major cuts last year, Congress preserved the N.I.H. budget at roughly $47 billion for 2026.

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“It is very frustrating to understand that this administration can circumvent dollars that were designated for our scientists,” said Senator Angela Alsobrooks, Democrat of Maryland.

Congress’s budget buoyed American scientists. By late 2025, many believed that they had weathered the worst of Trump-era funding problems. The N.I.H. spent aggressively toward the end of the last fiscal year, overcoming earlier blockages and delays.

The Supreme Court also let stand a lower court’s ruling that the policy behind the cancellation of more than $780 million in N.I.H. grants was probably unlawful, a victory for groups that had argued the terminations were arbitrary and capricious.

But the Trump administration was preparing a far more systematic crackdown on what it saw as unreliable research.

In August, Dr. Bhattacharya publicly outlined the agency’s new priorities, including opposition to “research based on ideologies that promote differential treatment of people based on race or ethnicity,” a template that could be used to guide grant reviews.

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Then, in December, the N.I.H. introduced its employees to the “computational text analysis tool,” allowing the agency to comb through new grant proposals and existing projects for phrases suggesting a grant “may not align with N.I.H. priorities,” a guidance document would later tell employees.

Roger Severino, a vice president of the conservative Heritage Foundation and a health official in the first Trump administration, said that weeding out such grants was necessary to rid the N.I.H. of the “politicization” of the Obama and Biden eras.

If the result was less spending on science, he said, that was only because the agency had been wasting money.

“There was a tremendous amount of bloat that grew up like barnacles on the N.I.H. research ship,” Mr. Severino said. “Those barnacles are being scraped off.”

Within some divisions of the N.I.H., the text search tool is flagging as many as half of grants, officials said, requiring staff scientists to extensively document how they will be reworked or why they already conform to agency priorities.

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Flagged grants address cancer, diabetes, autoimmune diseases, H.I.V., heart disease, stroke, Alzheimer’s disease, nutrition and prenatal care, internal documents show.

In part because many of them look at the use of screenings or treatments, they sometimes include mention of “inequities” in access to care or “minority” groups who disproportionately suffer from a disease, causing the system to deem the grants not “clean.”

In one case, a biological science grant was held up for a week because the proposal had used “sex” interchangeably with “gender,” a flagged word.

American scientists already spend some 40 percent of their time on grant-related administrative tasks. Now they are being deluged by ever more paperwork, said Dr. Michael Lauer, who led external grantmaking at the N.I.H. until last year.

And because the N.I.H. is awarding grants to far fewer researchers this year, the chances of success have rarely been lower.

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“This is lost time for all of us,” Dr. Lauer said. “Instead of spending their time doing science and hopefully making discoveries that will make us all healthier, they’re rewriting grant applications.”

Sheryl Gay Stolberg contributed reporting.


Methodology

The Times analyzed N.I.H. grants data from N.I.H. RePORTER for the fiscal years 2021 through 2026. The analysis excludes awards for intramural research conducted at the N.I.H. Clinical Center. The analysis focuses on new awards (Type 1 awards) and competitive renewals (Types 2, 4 and 9).

The analysis uses data through March 2026, the most recent month comparable to prior years. Previous records suggest that the data available on RePORTER for that month, however, may still be missing up to 10 percent of awards. The analysis accounts for that possibility.

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Lyrids Meteor Shower: How to Watch, Peak Time and Weather Forecast

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Lyrids Meteor Shower: How to Watch, Peak Time and Weather Forecast

Our universe might be chock-full of cosmic wonder, but you can observe only a fraction of astronomical phenomena with the naked eye. Meteor showers, natural fireworks that streak brightly across the night sky, are one of them.

The latest observable meteor shower will be the Lyrids, which has been active since April 14 and is forecast to continue through April 30. The shower reaches its peak April 21 to 22, or Tuesday night into Wednesday morning.

According to NASA, the Lyrids are one of the oldest known meteor showers, and have been enjoyed by stargazers for nearly 3,000 years. Their bright, speedy streaks are caused by the dusty debris from a comet named Thatcher. They appear to spring from the constellation Lyra, which right now can be seen in the eastern sky at night in the Northern Hemisphere.

The moon will be about 27 percent full tonight, appearing as a thick crescent in the sky, according to the American Meteor Society.

To get a hint at when to best watch for the Lyrids, you can use this tool, which relies on data from the Global Meteor Network. It shows fireball activity levels in real time.

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And while you gaze at the heavens, keep an eye out for other stray meteors streaking across the night sky. Skywatchers are reporting that the amount of fireballs is double what is usually seen by this point in the year.

There is a chance you might see a meteor on any given night, but you are most likely to catch one during a shower. Meteor showers are caused by Earth passing through the rubble trailing a comet or asteroid as it swings around the sun. This debris, which can be as small as a grain of sand, leaves behind a glowing stream of light as it burns up in Earth’s atmosphere.

Meteor showers occur around the same time every year and can last for days or weeks. But there is only a small window when each shower is at its peak, which happens when Earth reaches the densest part of the cosmic debris. The peak is the best time to look for a shower. From our point of view on Earth, the meteors will appear to come from the same point in the sky.

The Perseid meteor shower, for example, peaks in mid-August from the constellation Perseus. The Geminids, which occur every December, radiate from the constellation Gemini.

Michelle Nichols, the director of public observing at the Adler Planetarium in Chicago, recommends forgoing the use of telescopes or binoculars while watching a meteor shower.

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“You just need your eyes and, ideally, a dark sky,” she said.

That’s because meteors can shoot across large swaths of the sky, so observing equipment can limit your field of view.

Some showers are strong enough to produce up to 100 streaks an hour, according to the American Meteor Society, though you probably won’t see that many.

“Almost everybody is under a light-polluted sky,” Ms. Nichols said. “You may think you’re under a dark sky, but in reality, even in a small town, you can have bright lights nearby.”

Planetariums, local astronomy clubs or even maps like this one can help you figure out where to go to escape excessive light. The best conditions for catching a meteor shower are a clear sky with no moon or cloud cover, sometime between midnight and sunrise. (Moonlight affects visibility in the same way as light pollution, washing out fainter sources of light in the sky.) Make sure to give your eyes at least 30 minutes to adjust to seeing in the dark.

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Ms. Nichols also recommends wearing layers, even during the summer. “You’re going to be sitting there for quite a while, watching,” she said. “It’s going to get chilly, even in August.”

Bring a cup of cocoa or tea for even more warmth. Then lie back, scan the sky and enjoy the show.

Storm systems sweep across the country in early spring, and some will be obscuring skies tonight. But there will still be plenty of areas with clear skies, particularly in parts of the central United States.

“The best spot is going to be in the Upper Midwest,” said Rich Bann, a meteorologist with the Weather Prediction Center.

Minnesota, Wisconsin and Iowa will offer especially good sky-viewing weather and a beach on the Great Lakes could be a nice spot to look up at the stars.

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But don’t expect to view the show from Chicago, as Illinois could see some thunderstorms. The weather will be better in the Northern and Central Plains, particularly the eastern Dakotas.

High, wispy clouds are expected over the Ohio and Tennessee Valleys and into parts of the Mid-Atlantic. But, Mr. Bann said, “you may be able to see some shooting stars through thin clouds.”

Clouds will be draped across much of the Southeast and the Northeast, though there could be some clearing in Florida, Georgia, the Carolinas and Virginia. Remember, the meteors could be visible all night long. If you look outside and see clouds, try again later.

Catching the spectacle will be challenging across much of the West, particularly from Washington into Northern California, where a storm system is bringing rain and snow. That system will move east overnight.

There are likely to be some pockets of clear skies at times across southern Nevada, northwest Arizona and southwest Utah, Mr. Bann said.

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Amy Graff contributed reporting.

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FBI probes cases of missing or dead scientists, including four from the L.A. area

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FBI probes cases of missing or dead scientists, including four from the L.A. area

Amid growing national security concerns, the FBI said Tuesday that it has launched a broad investigation in the deaths or disappearances of at least 10 scientists and staff connected to highly sensitive research, including four from the Los Angeles area.

“The FBI is spearheading the effort to look for connections into the missing and deceased scientists. We are working with the Department of Energy, Department of War, and with our state and state and local law enforcement partners to find answers,” the agency said in a statement.

The FBI’s announcement comes after the House Oversight Committee announced that it would investigate reports of the disappearance and deaths of the scientists, sending letters seeking information from the agencies involved in the federal inquiry as well as NASA, which owns the Jet Propulsion Laboratory in La Cañada Flintridge, where three of the missing or dead scientists worked.

“If the reports are accurate, these deaths and disappearances may represent a grave threat to U.S. national security and to U.S. personnel with access to scientific secrets,” Reps. James Comer (R-Ky.), chairman of the committee, and Eric Burlison (R-Mo.) wrote in the letters.

President Trump told reporters last week that he had been briefed on the missing and dead scientists, which he described as “pretty serious stuff.” He said at the time that he expected answers on whether the deaths were connected “in the next week and a half.”

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Michael David Hicks, who studied comets and asteroids at JPL, was the first of the scientists who disappeared or died. He died on July 30, 2023, at the age of 59. No cause of death was disclosed.

A year later, JPL physicist Frank Maiwald died at 61, with no cause of death disclosed.

Two other Los Angeles scientists are part of the string of deaths and disappearances.

On June 22, 2025, Monica Jacinto Reza, a materials scientist at JPL, disappeared while on a hike near Mt. Waterman in the San Gabriel Mountains.

On Feb. 16, Caltech astrophysicist Carl Grillmair was fatally shot on the porch of his Llano home. The Los Angeles County Sheriff’s department arrested Freddy Snyder, 29, in connection with the shooting. Snyder had been arrested in December on suspicion of trespassing on Grillmair’s property.

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Snyder has been charged with murder.

There is no evidence at this point that the deaths and disappearances, which occurred over a span of four years, are connected.

A spokesperson for NASA, which owns JPL, said in a statement on X that the agency is “coordinating and cooperating with the relevant agencies in relation to the missing scientists.

“At this time, nothing related to NASA indicates a national security threat,” agency spokesperson Bethany Stevens wrote. “The agency is committed to transparency and will provide more information as able.”

Representatives from Caltech, which manages JPL, did not immediately respond to a request for comment.

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