Science
John Clements, Whose Research Saved Thousands of Babies, Dies at 101
Dr. John A. Clements, a towering figure in the field of pulmonary research who in the 1950s solved one of the great mysteries of the human lung, then helped to save thousands of lives by designing a drug to treat lung failure in premature infants, died on Sept. 3 at his home in Tiburon, Calif., north of San Francisco. He was 101.
The death was confirmed by his daughter Carol Clements.
In 1949, Dr. Clements was fresh out of Cornell University Medical College (now Weill Cornell Medical College) and working for the Army as a physiologist when he became intrigued by the miraculous mechanics of human breathing.
How could the millions of tiny air sacs in the lungs deflate when a person breathes out, but not collapse like a balloon? Dr. Clements theorized that there must be some chemical relaxing the surface tension of the air sacs, and he went on to identify the substance as a surfactant, a class of lubricants that work like household detergents.
In a 1956 paper, based on research done with a crude instrument he built himself, Dr. Clements demonstrated the presence of a surfactant in the lungs.
His work led to a breakthrough three years later by two Harvard researchers whom Dr. Clements advised: Pulmonary surfactant, they found, was absent in premature babies with undeveloped lungs who died of respiratory distress syndrome, or R.D.S.
The condition was once the leading cause of neonatal mortality in the United States, responsible for about 10,000 deaths annually in the 1960s.
One high-profile R.D.S. death was Patrick Bouvier Kennedy, the second son of President John F. Kennedy and Jacqueline Kennedy, who was born five and a half weeks prematurely in August 1963 and died within days.
“Back in the 1950s and early ’60s, if they had full-blown respiratory distress syndrome, more than 90 percent would die,” Dr. Clements said in a 2017 interview with iBiology Science Stories, a YouTube channel.
The discovery that premature babies lacked lung surfactant set off a worldwide rush to find a treatment. Some researchers tried replacement surfactants derived from sheep and cow lungs, but Dr. Clements believed animal surfactants were risky for tiny babies.
So, in response to a request from the premature infant nursery at the University of California, San Francisco, where he was a professor of pulmonary biology and pediatrics, Dr. Clements set out to develop a synthetic surfactant.
“It sounds incredibly naïve, or maybe at the other pole, really arrogant,” he said in a 2017 interview published on the university’s website, “but I said, ‘Well, I’ll make one for you’ — trying to accomplish in a few weeks or months what had taken divine providence millions of years — if you believe in evolution.”
His research led to the first synthetic lung surfactant, which the University of California licensed to the drugmaker Burroughs Wellcome and Company. Its drug Exosurf was the first replacement surfactant for clinical use approved by the Food and Drug Administration, in 1990.
Eventually, further study found that animal-derived surfactants worked better, and they are most often used today. Infant deaths from R.D.S. in the United States have declined to fewer than 500 a year.
In 1994, Dr. Clements won the Albert Lasker Clinical Medical Research Award for what was “widely regarded as the most important discovery in pulmonary physiology in the last 50 years,” according to the award citation.
Dr. Jordan U. Gutterman, the head of the awards at the time, noted how extraordinary it was for a scientist to be responsible for both a breakthrough in basic research and the development of a marketable treatment.
“It’s an incredible story of one man who looked at a problem and studied the physiology” and then solved the problem, he told The New York Times.
Dr. Clements donated the $25,000 in prize money to UNICEF.
John Allen Clements was born on March 16, 1923, in Auburn, N.Y., in the Finger Lakes region, the youngest of four children of Harry, a lawyer, and May Victoria (Porter) Clements. Both parents encouraged his childhood interest in scientific experiments. He rigged a shoe box with a flashing light that read “Scientist” and hung it in the window of the house. He made his own Tesla coil from scrounged-up parts, which the police told him he had to switch off after 6 p.m. because it was interfering with the neighbors’ radio.
Dr. Clements took advantage of an Army-paid accelerated program to complete his undergraduate work and an M.D. in five and a half years from Cornell. After his graduation in 1947, he worked for the Army Chemical Center in Maryland.
In 1949, he married Margot S. Power, a classical singer who went on to perform with the Baltimore Symphony, the Marin Symphony and the Carmel Bach Festival.
She died in 2022. In addition to their daughter Carol, Dr. Clements is survived by another daughter, Christine Clements.
At the University of California, San Francisco, which recruited Dr. Clements in 1959, he trained generations of physicians and researchers in his pulmonology lab.
After he retired in 2004, and into his 90s, he continued to drive to an office at the university two or three days a week, where he pursued research and advised others.
He parked his car in the same space for 50 years. Carol Clements said it exemplified his depth of focus: His laboratory work was always on his mind, and if he had parked in a different place, he would never be able to remember where.
Science
Video: NASA Announces Artemis III Crew
new video loaded: NASA Announces Artemis III Crew
transcript
transcript
NASA Announces Artemis III Crew
NASA announced the crew of Artemis III mission, which will fly to low-Earth orbit to test rendezvous and docking maneuvers with one or two lunar landers.
-
“I am excited to welcome you as the next crew in the Artemis journey to successfully return to the moon — this time to stay.” “I’m honored by the role that I’ve been given. I’m also very humbled by the task in front of us. But first and foremost, I’m grateful.” “So with that, the Artemis II crew, comrade, hands you the baton. You got the controls.” “As you know, we had a significant anomaly at our Launch Complex 36A on May 28. We’ve redoubled our efforts and are moving forward.”
By Alisa Shodiyev Kaff
June 9, 2026
Science
Santa Monica Mountains’ last steelhead trout survived the Palisades fire — and even had babies
Scientists feared the Santa Monica Mountains’ last remaining steelhead trout were dead, smothered by debris flows unleashed by the Palisades fire.
But the endangered fish surprised them: A team of biologists recently spotted 30 of the rare trout — and 21 babies — in Topanga Creek.
“There was a lot of happy dancing in the creek,” said Rosi Dagit, principal conservation biologist for the Resource Conservation District of the Santa Monica Mountains, which works with public and private landowners to conserve natural resources.
That’s because the steelhead here are endangered, at both the state and federal levels. Once, they swam in most streams of the Santa Monicas, but their numbers plummeted amid overfishing and coastal development. Increasingly frequent wildfire has further stressed their habitat. Topanga Creek, a biodiversity hot spot, is home to their last known population in the mountains that stretch from the Hollywood Hills to Point Mugu in Ventura County.
The trout that were spotted, including this one, are part of a distinct Southern California population that’s listed as endangered at the state and federal levels.
(RCDSMM Stream Team)
The California Department of Fish and Wildlife spearheaded a complex mission to rescue trout threatened by the Palisades fire that sparked in January 2025.
Time was of the essence. The fire hadn’t yet been fully contained. But rain was on the way, which would sweep massive amounts of sediment from the denuded hillsides into the water. Fish are often killed this way.
Crews stunned the fish with electricity, scooped them up in buckets, trucked them to a hatchery and ultimately moved them to Arroyo Hondo Creek in Santa Barbara County.
Within days, Topanga Creek was choked with mud. Some assumed the fish left behind were goners.
But in March, the conservation district’s team found four. The following month, when water conditions were clearer, they saw more.
“These fish continue to amaze me,” said Kyle Evans, environmental program manager for the state Department of Fish and Wildlife, who had seen the damage to the creek. “I had seen populations get wiped out in similar situations. So when I heard, I was thrilled.”
Evans surmises the fish that survived were in an area of the creek where less charred material and sediment were swept in.
“These fish likely hunkered down, were hiding under some rocks or places to try to get away from the main concentration of flow,” he said. “And luckily they weren’t buried.”
The ones that were spotted were fairly small, around 6 to 14 inches. Rainbow trout and steelhead trout are the same species, but with different lifestyles. If the fish remain in freshwater, they’ll be considered rainbows. However, they can migrate to the ocean and become steelhead, where they typically grow larger before returning to their natal waters to spawn.
Topanga Creek hasn’t fully recovered from the damage it sustained, but scientists say it’s looking better. Surveys last year were “so depressing,” Dagit said, with very few animals, and stretches that were essentially transformed into flat roads from all the sediment buildup. Some of the riparian canopy burned right down to the creek.
Then came 32 inches of rain over the last nine months, scouring out and moving sediment, creating deeper pools. Dagit said they recently found newt egg masses for the first time in years, as well as a few adult newts and many frogs. Plants that provide cover are starting to recover.
She provided photos comparing certain pools last year and this year, some dramatically transformed. In September 2025, the Shrine Pool could have been an overgrown hiking trail. This April, it was filled with shallow water.
The Shrine Pool in September 2025, left, and the same location in April 2026, right, with RCDSMM’s Isaac Yelchin donning a wetsuit.
(RCDSMM Stream Team)
Topanga Creek is home to another endangered fish, the small but hardy northern tidewater goby, often described as cute. Not long before the trout operation, Dagit led a rescue of hundreds of these fish too. Many were repatriated to the lagoon at the mouth of the creek in a moving ceremony last June.
There’s still the matter of what to do with the trout that were moved to Santa Barbara County last year. Evans would like to bring them home to the Santa Monicas at some point, but isn’t sure if it will happen. On one hand, they could bolster the small, genetically isolated surviving population. On the other, they might inadvertently bring in a disease or bacteria. There is some time to decide. Evans estimates the creek still needs to recover for two to three more years.
For now, the fish are functioning fine in their adopted creek. Experts worried the trauma wrought by the move would disrupt their spawning process, but they had babies that spring. This year, they spawned again.
Science
Pacifica pier cracks, another coastal casualty as seas continue to rise
The Pacifica Municipal Pier was shut down and taped off Thursday after city workers noticed cracks running through the landmark structure and concrete chunks falling into the ocean.
It’s just one of many coastal California structures that have recently crumbled under pressure from a rising and relentless ocean.
Officials from the small, beach city south of San Francisco said the pier was closed due to “cracking, separation, and displacement of the concrete walkway and structural elements.”
It will stay closed while structural engineers asses its safety.
Photos taken by city employees show a wide crack that runs from top to bottom and across the structure as well. Other photos show a large horizontal crack under the foundation of a small restaurant on the pier, the Chit Chat Cafe.
The cafe was also shut down.
This is not the first time the 53-year-old pier has shown signs of stress. In 2021, part of it was shut down after handrails along the edge collapsed. And in 2023, after a series of storms pummeled the Central California coast, damaging parts of the pier, the structure was partially closed for more than year.
Those same storms caused extensive damage in Aptos and Capitola, 70 miles south, where piers and waterfront infrastructure were swept away or damaged.
In 2024, a 150- to 180- foot section of the Santa Cruz wharf was ripped off by powerful waves.
At least 10 of the state’s dozens of coastal public piers were closed for part or all of 2024 due to structural damage sustained in winter storms since 2022. At least five others have longer-term upgrades planned to address structural issues.
“These things are costly to maintain,” said Zach Plopper, senior environmental director at Surfrider. “They are a part of our California coastal culture in many ways, but we’re going to need to reckon with, one, the state that they’re in, and two, the continuous and worsening threats they’re going to experience,”
He said most of the piers were constructed in the early 1900s, and they weren’t built to withstand decades of rough seas, storms and rising sea level.
“With this incoming El Niño, which is forecasted to be significant, and this marine heat wave we’re in the midst of, we’re kind of in uncharted waters as far as what this winter could bring in terms of storms and swells to the California coast, and we’re likely going to see a lot more damage,” he said. “Not just piers, but roads and other coastal infrastructure up and down the state.”
There was no storm in Pacifica earlier this week, so no single event could be blamed for the destruction.
However, a 2025 report from an outside engineering firm, GHD, found that several sections of the pier were in “poor” or “serious” condition, and they recommended closure before anticipated storms or events that could “subject the piles to high winds, swells and large waves.”
The firm found several areas of the pier where concrete was missing and rebar was exposed and corroding.
“The pier has continued to experience high winds and large waves in a harsh marine environment,” the engineers wrote in the report, noting that continuous exposure to seawater or marine spray was “detrimental” to the structure.
A 2023 city report estimated it would cost $19 million to repair.
That same year, a state law was enacted to require local governments along the California coast to plan for sea level rise in the coming decades.
Sea level has risen some 8 inches, on average, along the coast in the past 150 years, Plopper said, and researchers anticipate another foot in the next 25 years.
“We’re going to see profound shifts on our coastline, none that we have ever experienced before, and building static structures on the coast just doesn’t work all that well,” he said. “We’re going to have to make some really hard decisions.”
-
San Diego, CA4 minutes agoDaily Business Report: June 10, 2026, San Diego Metro Magazine
-
Milwaukee, WI7 minutes ago50 electric school buses to transport MPS kids starting this fall
-
Atlanta, GA12 minutes agoAtlanta Dream hold off Chicago Sky 82-75, Rhyne Howard becomes youngest player to hit rare WNBA milestone
-
Minneapolis, MN19 minutes agoOperation Metro Surge cost Minneapolis $700 million, city leaders say
-
Indianapolis, IN22 minutes agoPerson fatally shot on north side of Indianapolis
-
Pittsburg, PA27 minutes ago12+ things to do this weekend, from Pogopalooza and PizzaFest to the Beers of the Burgh Festival
-
Augusta, GA34 minutes ago
World Cup: Where to find a crowd to catch all the action
-
Washington, D.C37 minutes agoPermanent jewelry and pop-ups: Forever Adorned brings custom pieces to your stack