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Woman with advanced Alzheimer’s regained speech and memories after taking magic mushrooms

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Woman with advanced Alzheimer’s regained speech and memories after taking magic mushrooms

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A woman with advanced Alzheimer’s disease saw significant improvements in brain function after taking psilocybin-containing mushrooms.

That’s according to a case report recently published in Frontiers in Neuroscience, which focused on an elderly woman who had been living with Alzheimer’s disease for about 10 years. 

The Japanese American woman, whose name was not shared, had experienced severe functional decline for roughly five years. The Brazilian study authors described her as having advanced dementia, with very limited speech or communication, severe cognitive impairment, urinary incontinence and reduced mobility.

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She also depended on caregivers for assistance with daily living activities.

The woman received two sessions of psilocybin-containing mushrooms. The first was a 5-gram oral dose, followed by a 3-gram oral dose a month later.

A woman with advanced Alzheimer’s disease saw significant improvements in brain function after taking psilocybin-containing mushrooms, according to a published case report. (iStock)

After the first dose, she experienced profuse sweating and hyperthermia, followed by a prolonged sleep-like state.

Approximately 19 hours later, the patient “spontaneously initiated autobiographical conversation lasting several hours,” the researchers wrote.

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Over the following days and weeks, the woman experienced restored urinary continence, was able to walk independently and dress herself, and engaged in spontaneous conversation. She was also able to retrieve contextual memories, showed the ability to express emotions and maintained eye contact — smiling with others.

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After the second session, the authors reported that the woman had even greater speech capabilities, more facial expressions and humor, increased walking agility and continued continence.

Beyond the heavy sweating, hyperthermia and sleep-like state, the patient did not experience severe or persistent adverse effects, the researchers noted.

After the second session, the authors reported that the woman had even greater speech capabilities, more facial expressions and humor, increased walking agility and continued continence. (James MacDonald/Bloomberg via Getty Images)

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Although the reported benefits lasted for at least one month, the paper does not provide longer-term follow-up.

The authors said the findings should be interpreted with caution, as they are based on a single patient.

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The case also included no control group, standardized cognitive assessments, brain imaging biomarkers, electrophysiological monitoring or sleep studies, they noted.

The patient’s Alzheimer’s diagnosis was not confirmed with modern biomarkers, and other neurodegenerative conditions could not be completely ruled out, the study stated.

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As the patient may have experienced natural fluctuations in her medical condition, the study could not establish that psilocybin directly caused the woman’s improvements.

After the second session, the authors reported that the woman had increased walking agility. (iStock)

While the study suggests that psilocybin-containing mushrooms could temporarily reactivate brain function in people with late-stage dementia, the authors noted that controlled clinical trials, cognitive assessments, imaging scans and other tests are needed to confirm the findings.

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“Much more research is needed in larger, more representative study populations before any conclusions can be drawn about psilocybin’s safety and effectiveness in people living with Alzheimer’s or any other disease that causes dementia,” Courtney Kloske, Ph.D., director of scientific engagement at the Alzheimer’s Association in Chicago, told Fox News Digital.

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Kloske, who was not involved in the study, emphasized that people living with Alzheimer’s and their caregivers should talk with their doctor about all medications, vitamins, supplements and other substances they are taking.

“This helps healthcare providers understand how these products may interact with approved Alzheimer’s medications and other therapies to determine whether they could lead to unwanted side effects,” she advised.

“It might have some value in a carefully controlled setting.”

Dr. Marc Siegel, Fox News senior medical analyst, said he is “dubious” of the significance of the study because the effect was described as temporary and was limited to one case.

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“Also, there is a built-in danger of giving a hallucinogen to someone with this degree of mental impairment, because the behavioral effects are largely unpredictable and can be harmful,” Siegel, who also was not involved in the study, told Fox News Digital.

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“Having said that, I am not surprised to see that psilocybin could temporarily overcome or alter the gummed-up [brain] circuitry (with plaques) of advanced Alzheimer’s disease – so it might have some value in a carefully controlled setting.”

A medical expert said he is “dubious” of the significance of the study because the effect was described as temporary and was limited to one case. (Ethan Barton/Fox News Digital)

The findings come as several states have expanded legal access to psilocybin. (The substance remains federally illegal in the U.S. as a Schedule I substance.)

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Oregon began licensing psilocybin service centers in 2023, Colorado’s regulated natural medicine program became operational in 2025, and New Mexico enacted a Medical Psilocybin Act in 2025, according to state officials.

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Still, there are currently no FDA-approved psilocybin treatments for Alzheimer’s disease or dementia, and legal access remains limited to certain state-regulated programs or approved research settings.

Fox News Digital reached out to the researchers for comment.

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The ‘1776 Diet’: What Americans really ate during the nation’s founding

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The ‘1776 Diet’: What Americans really ate during the nation’s founding

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Many of the American colonists’ eating habits have made a comeback in recent years. They ate minimally processed, locally sourced whole foods and regularly incorporated organ meats into their meals.

Livestock and many Old World crops had already been introduced to North America by European explorers and settlers during the centuries before the nation’s founding.

Early settlers adapted European cooking traditions using ingredients available in North America, the Center for the Study of the Presidency and Congress (CSPC) reported.

Indigenous peoples introduced corn to the colonists, and it became a core ingredient in many of their recipes. Beans, squash, and potatoes were among the other crops that became incorporated into colonial cooking, according to the CSPC.

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“Cornmeal appeared in dishes such as hasty pudding — a thick porridge similar to polenta — and johnnycakes, simple griddle cakes that were popular from New England to the South,” History Facts reported.

Cornmeal Johnnycakes, roast pork and cream cheese are distinctly early-American foods the CSPC has recipes for on its website.

Corn became a staple of early colonists’ diets after Indigenous peoples introduced the crop to the settlers and taught them how to cultivate it. (iStock)

Regional customs and crops greatly influenced what the colonists ate. Rice and okra grew well and were plentiful in the South, where French and African influences also shaped eating habits. 

Dutch, English and German immigrants largely settled in the north and established the region’s culinary traditions.

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Seafood such as rockfish and crab dominated the diets of early Maryland settlers, NPR reported.

Meat was a status symbol, local food historian Joyce White told the publication. Beef was prized, and chicken was often saved for egg production.

“If it’s your pig or cow coming from your plantation, you don’t want to waste it,” White said.

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Thomas Jefferson was known for his decadent tastes and a fondness for French wine and macaroni and cheese. Records show that black-eyed peas, turnip greens and ham were also part of the Founding Father’s diet.

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Salted and preserved fish and meats, including bacon, sausage, liver pudding and offal, were staples of working-class people’s diets, while the upper classes indulged in such luxuries as white flour and sugar.

Interest in these traditional foods has resurfaced in recent years as some Americans seek diets centered on whole, minimally processed ingredients.

Founding Father Thomas Jefferson was known for his continental tastes and enjoyed French wine and macaroni and cheese. (iStock)

Advocates of the Make America Healthy Again movement, for instance, have promoted organ meats, or offal, as some of the cheapest and most nutrient-dense foods people can eat.

Stews that evolved as ingredients became available were also common an America’s early days.

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The amount of alcohol the colonists consumed was “staggering,” Adrian Miller, author of “The President’s Kitchen Cabinet,” told NPR.

“They were very open about how much they were drinking,” he said.

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George Washington wrote a recipe for “small beer” in a journal he kept as a young colonel in charge of the Virginia militia during the Seven Years’ War, Fox News Digital previously reported. The New York Public Library houses the journal.

“Small beer,” according to the library, derives its name from the small amount of alcohol it contains. It was quick to make, safer to drink because the brewing process helped eliminate bacteria in the water — and it was an “everyday, mainstay beverage,” the library reported.

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“While the 1776 Diet has some positives — such as emphasizing whole foods, home cooking and fewer ultra-processed foods — it’s not one I’d recommend following too literally,” registered dietician Lisa R. Young, adjunct professor of nutrition at New York University, told Fox News Digital.

Working-class colonists would often save chickens for their eggs, rather than consuming their meat. (iStock)

“Colonial Americans often ate foods like salted ham, organ meats and other preserved meats out of necessity,” she said. “Today, we know it’s best to limit processed and cured meats because they’re high in sodium and saturated fat, and organ meats, while nutrient-dense, are best eaten in moderation due to their high cholesterol content.”

Focus on the healthiest aspects of the 1776 diet, Young recommended. That includes plenty of fruits and vegetables, beans, whole grains, fish and lean proteins.

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“Of course, you can emulate the Founding Fathers’ diet for the week of the 250th anniversary,” she said. “What you eat for a day or a week won’t matter much in the scheme of things.”

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Some of the Founding Fathers drank a lot of ale, often in the morning, Young noted.

“We shouldn’t emulate that,” she said.

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Fourth of July fireworks pose hidden health risk for certain Americans, experts warn

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Fourth of July fireworks pose hidden health risk for certain Americans, experts warn

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Fireworks have been a quintessential part of Fourth of July celebrations across the nation for generations.

But as Independence Day festivities light up the night sky, the colorful displays can also pose serious health risks — especially to the lungs.

Nearly 300 million pounds of fireworks are released into the atmosphere each year in the U.S., according to the American Lung Association. This creates smoke filled with tiny particles, as well as gases like sulfur dioxide, carbon dioxide and carbon monoxide, which are “very harmful to our lungs.”

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The smoke from fireworks can also release harmful metals, like aluminum, manganese and cadmium, into the air.

Some illegal fireworks may contain lead, which the association describes as “extremely dangerous” due to its potential to cause lasting health damage.

Attendees watch the Independence Day fireworks display along the National Mall in Washington, D.C. (Probal Rashid/LightRocket via Getty Images)

“Inhaling any of these chemicals can irritate the lungs, making it hard to breathe and causing serious health problems, which is why it is important to avoid firework smoke whenever possible,” the group said in a public advisory.

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Air pollution levels increase by an average of 42% on the Fourth of July, according to a 2015 study.

Smoke from fireworks can worsen symptoms and cause flare-ups in those who have asthma or chronic obstructive pulmonary disease (COPD).

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Fine particle pollution has also been linked to more serious health consequences, including heart attacks, stroke, lung cancer and premature death, according to the American Lung Association.

The organization warned that children, older adults and pregnant women, as well as people with lung and heart disease, are especially vulnerable.

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Smoke from fireworks can worsen symptoms and cause flare-ups in those who have asthma or chronic obstructive pulmonary disease. (iStock)

Dr. Afif El-Hasan, member of the Lung Association’s board of directors, shared some advice for high-risk fireworks spectators in an interview with Fox News Digital.

Instead of using fireworks at home, El-Hasan recommends watching them from a distance.

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People with asthma who use a rescue inhaler should keep it close at hand in case fireworks trigger wheezing or other symptoms, the expert advised. Wearing a well-fitting N95 mask can also help reduce exposure to fine particles from fireworks smoke and debris.

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“If you are familiar with the area and the wind patterns, try to be upwind from the fireworks display and avoid areas where smoke may accumulate,” he said.

An expert recommends watching fireworks from a distance to avoid exposure to air pollution. (iStock)

The expert also recommends attending fireworks events with friends or family, so someone is available to help if a medical emergency arises.

“Make sure you have taken all of your preventative medication before a fireworks show,” El-Hasan advised. “If possible, take a car to the fireworks display. Try to park as close as possible to the event in case you have to get to the car quickly.”

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The expert also recommends drinking water immediately after the show to clear the upper airway. Changing and washing clothes upon returning home can also help to prevent smoke particles from accumulating in the home.

If case of shortness of breath or chest pain, it’s important to seek medical care immediately.

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Scientists discover possible link between 9/11 and accelerated aging

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Scientists discover possible link between 9/11 and accelerated aging

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A study of World Trade Center responders found that PTSD is associated with molecular changes linked to accelerated biological aging and a higher risk of chronic disease.

The study, led by Stony Brook University in New York, could offer new clues to the long-term physical health effects of post-traumatic stress disorder.

The researchers tested blood samples from 393 WTC responders, collected approximately 18 years after the September 11, 2001, attacks, according to a university press release.

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Out of the sampled responders, 232 were diagnosed with PTSD and 161 were not. Between the two groups, 114 proteins and seven metabolites were significantly different.

Firefighter Gerard McGibbon, of Engine 283 in Brownsville, Brooklyn, prays after the World Trade Center buildings collapsed on September 11, 2001. (Mario Tama/Getty Images)

In particular, the researchers detected changes in blood markers linked to brain function, immune activity, energy metabolism, protection against cell damage and how cells communicate and repair tissues.

Also reported were signs of accelerated biological aging in multiple organs — including the heart, kidneys, liver and lungs — among responders with PTSD.

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These discoveries could help explain why people with long-term PTSD are at greater risk for chronic conditions such as heart disease, lung disease, cognitive decline and other age-related illnesses.

“This study found that chronic PTSD is associated with long-lasting biological changes throughout the body, affecting multiple organs and biological systems decades after their traumatic exposure,” lead study author Benjamin Luft, director and principal investigator at the Stony Brook WTC Wellness Program, told Fox News Digital.

“Traumatic experiences can produce lasting biological changes that persist for decades.”

The study reinforces the view that PTSD is a “whole-body illness” rather than simply a mental health disorder, he noted.

“Traumatic experiences can produce lasting biological changes that persist for decades,” Luft said. “These changes appear to accelerate aspects of biological aging and may increase the risk of many chronic diseases.”

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Several proteins that are critical for healthy brain function were also altered in those with PTSD, the researchers found.

“Many of these proteins play critical roles in helping brain cells communicate with one another, repair damage and maintain healthy connections that support memory and thinking,” Luft said.

A New York firefighter is pictured amid the rubble of the World Trade Center following the 9/11 attacks in 2001. (Universal History Archive/Universal Images Group via Getty Images)

The study – which was funded in part by the CDC, the National Institute for Occupational Safety and the National Institutes of Health – was published in Nature Communications.

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Luft said the findings should be viewed with “cautious optimism.”

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“The research provides compelling evidence that PTSD is associated with long-lasting biological changes throughout the body, including signs of accelerated aging, altered metabolism and changes in proteins involved in brain health,” he said.

“These findings strengthen the growing recognition that PTSD is not simply a mental health disorder, but a condition that can have lasting effects on physical health as well.”

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Dr. Marc Siegel, Fox News senior medical analyst, was not involved in the study but called the results “fascinating.”

“This speaks to the complex reality that PTSD is not an isolated psychiatric event due to emotional trauma alone, but that it is also tied in with physical trauma,” he told Fox News Digital. “The stress is both emotional and physical, and leads directly to immune dysregulation and aging processes.”

“These findings strengthen the growing recognition that PTSD is not simply a mental health disorder, but a condition that can have lasting effects on physical health as well,” the researcher said. (iStock)

“The chronic diseases that resulted from high exposure in the aftermath of the 9/11 World Trade Center attacks were conjoined in terms of the impact on physical and emotional well-being, longevity and effects on multiple organ systems, as well as core metabolic and immunological processes,” the doctor added.

Study limitations

There were some limitations to the findings, the researchers noted.

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“Because all measurements were taken at one point in time, the research can only show an association — not that PTSD directly caused the changes,” Luft noted.

“We are currently doing studies in these patients examining multiple time points to see whether the changes in specific proteins and metabolites precede clinical changes.”

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Also, because the study was done on a unique population – World Trade Center responders who experienced very specific trauma and environmental exposures – the findings may not apply to everyone with PTSD, “such as combat veterans, survivors of abuse or people who experienced other types of trauma.”

Several proteins that are critical for healthy brain function were also altered in those with PTSD, the researchers found. (iStock)

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Women are not well-represented in the study, comprising only 10% of responders.

“Blood tests cannot tell us exactly what is happening inside the brain,” Luft said. “Although many of the altered proteins are related to brain function, blood measurements are only an indirect reflection of processes occurring in the brain.”

Looking ahead

Additional studies are needed to determine whether these blood markers can predict disease progression or treatment response.

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“From a public health and policy perspective, the study reinforces the importance of recognizing PTSD as a chronic medical condition with significant long-term health implications,” Luft said.

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“Investing in early diagnosis, comprehensive treatment and long-term follow-up for trauma survivors, including our first responders and veterans, may improve quality of life while reducing the burden of chronic disease.”

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