Boston, MA

Boston Scientific hits all endpoints in CRM trial

Published

2 years ago

May 20, 2024

Boston Scientific hits all endpoints in CRM trial

The Boston Scientific device consists of an Emblem subcutaneous implantable defibrillator system and Empower leadless pacemaker. Credit: Shutterstock / jeffy11390.

Boston Scientific has announced six-month positive results from its ongoing pivotal MODULAR ATP clinical trial examining the company’s modular cardiac rhythm management (mCRM) technology.

The findings published in the New England Journal of Medicine detail how the system successfully met its primary and secondary endpoints in terms of safety and efficacy, seeing 97.5% of participants experience no complications following the procedure, with an anti-tachycardia pacing (ATP) success rate of 61.3%.

The Boston Scientific device consists of an Emblem subcutaneous implantable defibrillator (S-ICD) system and Empower leadless pacemaker (LP) which coordinate painless intracardiac anti-tachycardia pacing.

Cardiology and Electrophysiology consultant for Boston Scientific, Reinoud Knops said: “We saw excellent overall clinical performance of the mCRM System in this study, including a high rate of communication success from the S-ICD to the leadless pacemaker, and a low rate of major leadless pacemaker complications.

“These findings are noteworthy, as high percentages of communication success and pain-free termination of spontaneous arrhythmia episodes indicate a potential upgrade pathway for patients currently implanted with an S-ICD who develop a need for ATP or pacing.”

Boston Scientfic’s findings were presented before an audience at the Boston-based Heart Rhythm 2024 conference where the company also revealed results from its APPRAISE ATP clinical trial, a prospective, randomised, multicenter study evaluating ATP as a method of treating ventricular tachycardias in primary prevention (PP) patients. That trial has enrolled 2,626 patients indicated to receive an ICD at 134 centres worldwide.

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Research by GlobalData details how the wearable technology market is forecast to grow from $99.5bn in 2022 to $290.6bn in 2030.

Kenneth Stein, chief medical officer for Boston Scientific, said: “Together, data from the MODULAR ATP and APPRAISE ATP trials reinforce the promise of the groundbreaking mCRM System, illustrating a clear path forward for physicians to offer therapies that prevent sudden cardiac death and deliver ATP for the small number of patients who benefit from it.

“Instead of subjecting all patients to the risks of more invasive approaches, such as placing leads in the heart or tunnelling them under the sternum to provide therapies they might not require, these data indicate physicians may have the opportunity to tailor therapy to the patient’s individual needs and health.”

Elsewhere in the field of anti-tachycardia pacing, health tech company Element Science has received an EU CE mark certification and UK Conformity Assessed (UKCA) marketing for its own digital wearable defibrillator. At the same time, the US Food and Drug Administration (FDA) has approved Medtronic’s Aurora EV-ICD MRI SureScan extravascular implantable cardioverter-defibrillator.

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Boston, MA

!$+∇√$[+[!LIVESTREAMs!]+] Minnesota Wild vs Boston Bruins Live Free Streams On Tv Channel 2026-03-29

Published

10 hours ago

March 29, 2026

Press Room

Minnesota Wild vs Boston Bruins

HERE’S (*WAY TO WATCH*) Minnesota Wild VS Boston Bruins Ｆｒｅｅ LIVE 2026-03-29 Rose Bowl Parade 2026 live: Rose Bowl Parade 2026 look to seize control of thrilling Rose Bowl Parade 2026. Every team in the Rose Bowl Parade 2026 has two wins apiece as we go into the final two game weeks. Rose Bowl Parade 2026 will host Rose Bowl Parade 2026 at Live NHL mAtch Durban’s Kings Park Stadium with the Rose Bowl Parade 2026 a single point ahead of Rose Bowl Parade 2026 in the standings and just one behind leaders Rose Bowl Parade 2026.

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Boston, MA

+)WAY TO WATCH Ｆｒｅｅ Boston Legacy FC vs Utah Royals LIVE

Published

22 hours ago

March 29, 2026

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Boston Legacy FC vs Utah Royals

Boston Legacy FC vs Utah Royals LIVE GAME: Boston Legacy FC vs Utah Royals look to seize control of thrilling Boston Legacy FC vs Utah Royals. Every team in the Boston Legacy FC vs Utah Royals has two wins apiece as we go into the final two game weeks. Boston Legacy FC vs Utah Royals will host Boston Legacy FC vs Utah Royals at Boston Legacy FC vs Utah Royals Park Stadium with the Boston Legacy FC vs Utah Royals a single point ahead of Boston Legacy FC vs Utah Royals in the standings and just one behind leaders Boston Legacy FC vs Utah Royals.

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Boston, MA

Red Sox at Reds preview: Sonny Gray makes his first start for Boston – The Boston Globe

Published

1 day ago

March 28, 2026

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Red Sox at Reds preview: Sonny Gray makes his first start for Boston – The Boston Globe

Gray, acquired in a November trade from the St. Louis Cardinals, was one of Boston’s key rotation additions, along with Ranger Suarez, in the offseason. He was 14-8 with a 4.28 ERA in 2025.

“He’s very specific about his work. Every day has a purpose,” Red Sox manager Alex Cora said of Gray. “Two hundred strikeouts, that’s something that we were looking for. The competitor. Every five days, this guy is going to give you everything.”

In his five career appearances against the Reds, Gray is 1-3 with a 4.18 ERA.

“It’s pretty much one of the only things that is continuing to push me, is to get to a World Series, to win a World Series, to pitch in big games,” said Gray. “I love the moment, and I am chasing that moment.”

Here’s the preview:

RED SOX (1-0): TBA

Pitching: RHP Sonny Gray

REDS (0-1): TBA

Pitching: RHP Brady Singer

Time: 4:10 p.m.

TV, radio: NESN, WEEI-FM 93.7

Red Sox vs. Singer: Wilyer Abreu 2-5, Roman Anthony 1-2, Willson Contreras 2-7, Jarren Duran 3-10, Caleb Durbin 0-1, Isiah Kiner-Falefa 6-16, Marcelo Mayer 0-1, Andruw Monasterio 1-4, Carlos Narváez 1-1, Ceddanne Rafaela 1-5, Trevor Story 0-4, Connor Wong 2-8, Masataka Yoshida 2-7

Reds vs. Gray: Will Benson 0-5, Elly De La Cruz 5-11, TJ Friedl 1-8, Ke’Bryan Hayes 4-17, Nathaniel Lowe 2-10, Noelvi Marte 0-5, Matt McLain 2-2, Spencer Steer 4-9, Tyler Stephenson 0-8, Eugenio Suárez 7-13, Jose Trevino 0-2

Stat of the day: Sal Stewart become the first Cincinnati rookie since 1958 to record three hits on Opening Day.

Notes: Cincinnati sends righthander Brady Singer (14-12, 4.03 in 2025) to the mound … With Hunter Greene and Nick Lodolo already on the injured list to start the season, Singer is considered one of Cincinnati’s most durable pitchers, leading the Reds with 32 starts last season … Singer has made five career starts against Boston, posting a 2-2 record with a 4.88 ERA over 24 innings … His last appearance against the Red Sox, on July 1 in Boston, ended after just three innings when he allowed two earned runs on three hits.

Cam Kerry can be reached at cam.kerry@globe.com.

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