Connect with us

Boston, MA

Boston Scientific hits all endpoints in CRM trial

Published

on

Boston Scientific hits all endpoints in CRM trial


Boston Scientific has announced six-month positive results from its ongoing pivotal MODULAR ATP clinical trial examining the company’s modular cardiac rhythm management (mCRM) technology.

The findings published in the New England Journal of Medicine detail how the system successfully met its primary and secondary endpoints in terms of safety and efficacy, seeing 97.5% of participants experience no complications following the procedure, with an anti-tachycardia pacing (ATP) success rate of 61.3%.

Advertisement

The Boston Scientific device consists of an Emblem subcutaneous implantable defibrillator (S-ICD) system and Empower leadless pacemaker (LP) which coordinate painless intracardiac anti-tachycardia pacing.

Cardiology and Electrophysiology consultant for Boston Scientific, Reinoud Knops said: “We saw excellent overall clinical performance of the mCRM System in this study, including a high rate of communication success from the S-ICD to the leadless pacemaker, and a low rate of major leadless pacemaker complications.

“These findings are noteworthy, as high percentages of communication success and pain-free termination of spontaneous arrhythmia episodes indicate a potential upgrade pathway for patients currently implanted with an S-ICD who develop a need for ATP or pacing.”

Boston Scientfic’s findings were presented before an audience at the Boston-based Heart Rhythm 2024 conference where the company also revealed results from its APPRAISE ATP clinical trial, a prospective, randomised, multicenter study evaluating ATP as a method of treating ventricular tachycardias in primary prevention (PP) patients. That trial has enrolled 2,626 patients indicated to receive an ICD at 134 centres worldwide.

Access the most comprehensive Company Profiles
on the market, powered by GlobalData. Save hours of research. Gain competitive edge.

Advertisement

Company Profile – free
sample

Your download email will arrive shortly

We are confident about the
unique
quality of our Company Profiles. However, we want you to make the most
beneficial
decision for your business, so we offer a free sample that you can download by
submitting the below form

By GlobalData

Advertisement





Advertisement

Advertisement

Advertisement



Visit our Privacy Policy for more information about our services, how we may use, process and share your personal data, including information of your rights in respect of your personal data and how you can unsubscribe from future marketing communications. Our services are intended for corporate subscribers and you warrant that the email address submitted is your corporate email address.

Advertisement

Research by GlobalData details how the wearable technology market is forecast to grow from $99.5bn in 2022 to $290.6bn in 2030.

Kenneth Stein, chief medical officer for Boston Scientific, said: “Together, data from the MODULAR ATP and APPRAISE ATP trials reinforce the promise of the groundbreaking mCRM System, illustrating a clear path forward for physicians to offer therapies that prevent sudden cardiac death and deliver ATP for the small number of patients who benefit from it.

Advertisement

“Instead of subjecting all patients to the risks of more invasive approaches, such as placing leads in the heart or tunnelling them under the sternum to provide therapies they might not require, these data indicate physicians may have the opportunity to tailor therapy to the patient’s individual needs and health.”

Elsewhere in the field of anti-tachycardia pacing, health tech company Element Science has received an EU CE mark certification and UK Conformity Assessed (UKCA) marketing for its own digital wearable defibrillator. At the same time, the US Food and Drug Administration (FDA) has approved Medtronic’s Aurora EV-ICD MRI SureScan extravascular implantable cardioverter-defibrillator.


Advertisement





Source link

Boston, MA

Free December events in Boston: Hanukkah celebrations, new play readings, and more – The Boston Globe

Published

on

Free December events in Boston: Hanukkah celebrations, new play readings, and more – The Boston Globe


Though the bitter New England wind is upon us, the holiday calendar is just warming up. This week’s schedule features a fire-and-ice Hanukkah celebration in Watertown, readings of two soon-to-debut theatrical works, and offbeat holiday film screenings at a dive bar. However you choose to get ready for the festivities, here are some no-cost and discounted events across Greater Boston and beyond for the week of Dec. 15-21.

A HOT AND COLD HANUKKAH Chabad Watertown’s Hanukkah celebration kicks off at 4:45 p.m., live performances featuring fire breathing, flaming prop juggling, and other heated tricks. Then, at 5 p.m., Chabad’s 7-foot-tall ice menorah will be lit, followed by a gelt drop, when chocolate coins will be parachuted from above for attendees to catch. Crafts and games will be set up around the venue, and free hot chocolate and doughnuts will be offered while supplies last. Dec. 15, 4-6 p.m. RSVP recommended. Arsenal Yards, 130 Arsenal St., Watertown. arsenalyards.com

HOLIDAY HORRORS There’s nothing like the gritty texture of VHS that elevates a scary movie: WickedVHS, a series of free public screenings of VHS movies at bars, screens a double feature of two creepy Christmas movies at the Model Café on Monday. Film names won’t be revealed until you’re at the event, but a few clues have been offered. The first pick is a childhood horror staple, featuring cutesy monsters who turn evil once you feed them at night; the other is a folkloric fable about Santa’s evil twin. Dec. 15. 7 p.m. and 9 p.m. 21+. Model Café, 7 North Beacon St., Allston. instagram.com/wickedvhs

On Sept. 30, viewers attended a Wicked VHS double-screening of “The Faculty” and “Scream 2” at Deep Cuts in Medford.Craig Silva/Wicked VHS

GONE CAROLING Caroling isn’t just an activity from the days of old: The New School of Music hosts a drop-in session for curious carolers to practice for the doorways. The session is led by NSM instructor Joe Reid, who will teach attendees a wide variety of Christmas, Hanukkah, and general winter tunes, demonstrate different ways to harmonize, and provide live piano accompaniment. Hot cider will be provided to soothe your throat, and free Christmas cookies can keep spirits high. Dec. 16, 6:30-8 p.m. New School of Music Concert Room, 25 Lowell St., Cambridge. newschoolofmusic.org

Advertisement

NEVER-BEFORE-SEEN THEATER The Huntington Theatre’s Winter New Play Intensive, a development program for new plays, will present its two projects this season for the first time. “Blue Train,” which has its live reading on Tuesday, is a familial drama about a son who hopes to inherit his ailing father’s beach retreat. Wednesday, it’s “Three Bears,” a sci-fi epic about two wandering spacemen attempting to reach a distant outpost before they run out of the necessary resources for their journey. Dec. 16 and 17, 7 p.m. The Maso Studio in the Huntington Theatre, 264 Huntington Ave. huntingtontheatre.org

The Huntington Theatre will present two live readings of new works from its Winter New Play Intensive.MIKE RITTER

CELEBRATORY CRAFTS Before the holidays are upon us, visit Assembly Row for some casual activities. Attendees can take part in various family-friendly crafts celebrating Christmas and Hanukkah, including ornament-crafting, snowflake-making, and drawing, and indulge in some free hot chocolate while supplies last. The J.P. Licks deck also turns into a dancefloor with tunes from DJ Axelrod, who will play house beats to keep the crowd moving and grooving. Dec. 20, 1-3 p.m. J.P. Licks Deck at Assembly Row, 355 Artisan Way, Somerville. assemblyrow.com

MENORAH AT THE MUSEUM The MFA’s Hanukkah celebration, which features discounted entry for the museum’s $5 Third Thursdays event. This month features activities and exhibitions celebrating Jewish traditions beginning at 5 p.m. At 5:30 p.m., catch a performance from the Global Yiddish Orchestra, or, at 5:45 p.m., a performance from AJ Rubin that blends Jewish folk music and clowning. Among the many festivities are tours and live readings celebrating Jewish history, an interactive scavenger hunt to gather candles for a menorah, a drop-in dreidel-decorating workshop, and a face-painting booth. Dec. 18, 5-10 p.m. Museum of Fine Arts, 465 Huntington Ave. mfa.org

PET PORTRAITS Furry friends can get in on the festive fun at the Paws and Claus event hosted by Bond Vet, a veterinary clinic with several locations in Greater Boston. Pets will get their photos taken for free alongside a (human) Santa Claus, for a professional-looking portrait their owners can put on kitschy greeting cards. Dogs and cats can snag a free treat, and humans get hot chocolate for tagging along. Dec. 20, 6:30-7:30 p.m. Bond Vet, 320 Foley St., Somerville. bringfido.com

Check individual event websites for the most up-to-date information.

Send info on free events and special offers at least 10 days in advance to ryan.yau@globe.com.

Advertisement

Ryan Yau can be reached at ryan.yau@globe.com.





Source link

Continue Reading

Boston, MA

Proposed “perfect” Red Sox trade sees Boston deal Jarren Duran, prospects for $15.5 million two-time All-Star ace

Published

on

Proposed “perfect” Red Sox trade sees Boston deal Jarren Duran, prospects for .5 million two-time All-Star ace


The Boston Red Sox found their ace in Garrett Crochet this year, after trading for him around this time last year. Now, they’ve made some moves to finally get him some support in the rotation, but none of those moves are truly a No. 2 to back him up.

Fansided’s Cody Williams believes he has the perfect trade for a name that’s been floated around as an option: Milwaukee Brewers All-Star Freddy Peralta. 

“While Boston has long looked like an obvious suitor for Peralta, the trade assets haven’t necessarily lined up perfectly for both them and Milwaukee…Now, the Brewers still aren’t in need of outfield help, so to speak, but there is certainly room to upgrade over the likes of Jake Bauers, Garrett Mitchell or Blake Perkins, which Duran or Abreu would allow them to do. Furthermore, in typical fashion for Milwaukee, they could flip an asset they’re unlikely to be able to pay in Peralta for immediate major-league upgrades with plenty of club control at low cost and prospects that could help keep the ball rolling under Pat Murphy,” Williams wrote. 

MORE: Cubs predicted to trade for $3.75 million 150 SO ace to create 1-2 punch with Shota Imanaga

Advertisement

The trade would look like this: 

Red Sox get: RHP Freddy Peralta

Brewers get: OF Jarren Duran, SS Franklin Arias (No. 1 Prospect), RHP Juan Valera (No. 12 Prospect) 

MORE: Mariners predicted to trade for $5.75 million All-Star, Gold Glove as amazing replacement for Jorge Polanco

Peralta posted a 17-6 record, a 2.70 ERA, 204 Ks, and a WHIP of 1.075 over 176 innings pitched last season. Combine him with Crochet, and the Sox have a World Series-contending-level rotation. 

Advertisement

The only problem with this is it’s basically a one-year rental. Peralta’s contract is up after this year, and he’s projected to get a five-year, $152 million deal. 

The Sox have shown they don’t believe in giving long-term contracts out to players over 30, and Peralta will be 30 in the upcoming season. Hopefully, the Sox make an exception, get uncomfortable like they said they would, and pursue this trade.

MORE MLB NEWS

Braves predicted to be top trade candidate for $325 million two-time World Series MVP, five-time All-Star as massive upgrade over Mauricio Dubon

Red Sox predicted to be top landing spot for $116.5 million three-time All-Star, two-time Silver Slugger, would be massive upgrade from David Hamilton

Advertisement

Phillies predicted to be top trade candidate for $7.7 million All-Star MVP, would replace Nick Castellanos



Source link

Continue Reading

Boston, MA

BU spoils Northeastern final game at Matthews Arena

Published

on

BU spoils Northeastern final game at Matthews Arena


BOSTON – Before the lights went out at Matthews Arena for the last time, they shined brightly on Boston University center Brandon Svoboda.

The sophomore from Pittsburgh scored two goals including the game-winner at 18:21 of the third to lift the Terriers to a 4-3 victory over Northeastern, on Saturday night. Svoboda’s fourth of the season was the final goal scored at Northeastern’s historic Matthews Arena.

The Terriers’ victory over the Huskies was the last sporting event played inside Matthews Arena, which officially opened its doors as Boston Arena in April of 1910.

“I got a lucky bounce and I capitalized on it and put it in the back of the net,” said Svoboda. “Playing the last game ever in this building is pretty special and what was it, 1910 this place was built so it was pretty special being the last team playing in this building.

Advertisement

“We are a young group and we are figuring it out so it was obviously a big deal to get a W in the last game in this arena.”

BU improved to 9-8-1 and 6-3-0 in Hockey East going into the semester break while the No. 11 Huskies fell to 10-6-0 and 5-4-0 in the conference.

“It was just a big win for us going into the semester break,” said BU coach Jay Pandolfo. “The first half has not been ideal for us so to finish it that way, to come back in the third period to win a hockey game in this environment, where this is their last home game here and they wanted to win and we found a way to pull it off.”

Northeastern purchased the structure in 1979 and renamed it Matthews Arena three years later. The demolition of the old barn nestled between Mass. Ave and Gainsborough Street will begin in January and the new arena is scheduled to go online in September of 2028.

“Having a new facility is definitely a big selling point,” said NU coach Jerry Keefe. “It is going to have all the amenities you need to develop players and I think this generation of recruits like the shiny and the new.”

Advertisement

The first Beanpot Tournament was played at Boston Arena in 1952, so it seemed appropriate that Northeastern would play its final game against a neighboring Beanpot opponent. BU played its home games at Boston Arena from 1918 to 1971 before moving into its new facility on Babcock Street.

Pandolfo enjoyed many Matthews moments both on the ice and behind the bench. Pandolfo also played in the final Beanpot game at the old Boston Garden.

“I always enjoyed playing here that’s for sure,” Pandolfo said. “It was a fun place to play and I always enjoyed it and I enjoyed coaching there. It is a great environment and a special old building.

“That’s the biggest attachment for me and that I just enjoyed it. My grandfather played at Northeastern, my mom’s dad and that makes it special as well. It was also Boston University’s home rink as well for a long time and that is a big reason we are here closing it out with Northeastern.”

The Huskies had some extra zip in their blades that created several scoring opportunities, all of which deftly handled by BU netminder Mikhail Yegorov.

Advertisement

NU went up 1-0 on a power play goal by freshman center Jacob Mathieu at 11:28 of the first. Mathieu found an opening outside the BU crease and redirected Giacomo Martino’s wrister from the left circle for his fifth of the season.

NU went up 2-0 at 14:36 when junior center Tyler Fukakusa finished a two-on-one break with his second goal of the season. BU got on the board when Svoboda netted a power play goal at 17:40, his third of the season.

“We were playing fine but we just made some mistakes so to get out of that first period 2-1 was important no question about that,” said Pandolfo.

BU tied the game 2-2 on sophomore center Sacha Boisvert’s second of the season at 13:38 of the second. NU went up 3-2 when sophomore left wing Joe Connor beat the buzzer at 19:59 with his sixth of the season. NU tied the game 3-3 on Kamil Bednarik tally at 18:02 of the third. Svoboda would score 19 seconds later to complete the comeback.

“You give up a late goal at the end of the second period after a power play, that can really hurt you,” said Pandolfo. “But our guys were determined to come back.”

Advertisement



Source link

Continue Reading

Trending