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Boston hospital enrolls patients for Long COVID study: ‘Hopefully we can get some answers’

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Boston hospital enrolls patients for Long COVID study: ‘Hopefully we can get some answers’


As millions of people across the country continue to suffer from long COVID, a Boston hospital is launching phase 2 clinical trials to test potential treatments for the debilitating condition.

Brigham and Women’s Hospital is the first site to enroll and begin phase 2 clinical trials for the National Institutes of Health “Researching COVID to Enhance Recovery” (RECOVER) Initiative.

The phase 2 clinical trials will evaluate at least four potential treatments for long COVID, with additional clinical trials to test seven more treatments in the coming months. Treatments will include drugs, biologics, medical devices and other therapies.

“Long COVID is a real bear, and a lot of our patients are suffering from this complicated condition,” Lindsey Baden, VP of clinical research at the Brigham, told the Herald on Tuesday.

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“We’re hoping we can enroll this quickly,” Baden added. “Hopefully we can get some answers, so we know how to treat our patients better.”

RECOVER is a large, nationwide research program designed to understand, treat and prevent long COVID, which is marked by long-term symptoms following a COVID infection.

These clinical trials are focusing on viral persistence and cognitive dysfunction.

RECOVER-VITAL will study viral persistence, which could occur if the virus stays in the body and causes the immune system to not function properly or causes damage to organs. The first intervention will test a longer dose regimen of the antiviral Paxlovid than is used for treating acute COVID to see if it improves the symptoms of patients with long COVID.

RECOVER-NEURO will examine interventions for cognitive dysfunction related to long COVID, including brain fog, memory problems, as well as difficulty with attention, thinking clearly, and problem-solving. Interventions under this protocol will include a series of web-based brain training programs that have been used to improve cognitive function and help brain activity and blood flow.

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“Over the past year, efforts have largely been focused on observational studies to understand the symptoms of long COVID and associated underlying pathobiology. We are now pleased to begin the next phase in this process and launch clinical trials to treat patients with significant symptoms associated with long COVID,” Baden said.

The Brigham is looking to enroll dozens of patients for the clinical trials. Brigham and Women’s Hospital will be partnering with local communities to raise awareness about long COVID and offer opportunities to participate in the RECOVER clinical trials.

Those interested in learning more about enrolling in the RECOVER clinical trial should visit www.recovercovid.org.



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Boston, MA

What is the Boston Calling Music Festival lineup? Here is how to buy last-minute tickets

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What is the Boston Calling Music Festival lineup? Here is how to buy last-minute tickets


Calling all music festival fans, you better be going to Boston Calling Music Festival this weekend.

The Boston-based music festival will take place over Memorial Day weekend from May 24-26 at the Harvard Athletic Complex in Boston, Mass.

Some of the music industry’s biggest artists and bands will be headlining, such as Ed Sheeran, Reneé Rapp and Young The Giant.

The festival will have four stages for artists to perform on, art fixtures, and even a 100-foot Ferris wheel.

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Plus there will be over 30 local food vendors where festival goers can enjoy all types of cuisine from New England lobster rolls to southern BBQ.

You shouldn’t miss out on this festival, so here is how you can get last-minute tickets.

Who are the headliners for the Boston Calling Music Festival?

The fan-favorite artists who are headlining the music festival are Ed Sheeran, Leon Bridges, Tyler Childers, Trey Anastasio & Classic Tab, The Killers and Hozier.

There are also a wide variety of artists performing at the Boston festival, including Reneé Rapp, Young The Giant, Luke Hemmimgs, Khruangbin, Megan Thee Stallion, The Revivalists and so many others.

Where can I buy Boston Calling Music Festival Tickets?

Music festival fans can find tickets for Boston Calling on the festival website, as well as StubHub, Vivid Seats, TicketCity and SeatGeek.

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First-time Vivid Seats users can save $20 on ticket orders over $200 with promo code NJ20 at checkout.

TicketCity users can save $15 on orders over $400 using promo code TCITYSAVE15 at checkout.

The complete artist lineup for the Boston Calling Music Festival is available here.

Upcoming festivals in 2024

The Boston Calling Music Festival is not the only music event to look forward.

Here is a list of upcoming festivals you do not want to miss: Barefoot Country Music Festival, Governors Ball Music Festival, Bonnaroo Music & Arts Festival and Sad Summer Festival.

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Our journalism needs your support. Please subscribe today to NJ.com.

Nicole Iuzzolino can be reached at niuzzolino@njadvancemedia.com. Have a tip? Tell us at nj.com/tips.



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Boston Celtics Player Officially Ruled Out For Game 1 Against Pacers

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Boston Celtics Player Officially Ruled Out For Game 1 Against Pacers


On Tuesday evening, the Boston Celtics and Indiana Pacers will play Game 1 of the Eastern Conference Finals in Massachusetts.

For the game, the Celtics will officially be without Kristaps Porzingis.

The 2018 NBA All-Star has missed each of the previous six games, so this will be his seventh straight out of the starting lineup.

Via Zack Cox of NESN: “The Celtics officially ruled out Kristaps Porzingis for Game 1 tomorrow night. Seventh straight DNP for him.

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Joe Mazzulla today said Porzingis is “working really hard to come back as fast as he can” but wasn’t ready to begin practicing with the team.”

The Celtics did not have Porzingis in their second round series with the Cleveland Cavaliers, but they were still able to win in just five games.

He is in his first year with the Celtics, and finished the regular season with averages of 20.1 points, 7.2 rebounds, 2.0 assists and 1.9 blocks per contest while shooting 51.6% from the field and 37.5% from the three-point range in 57 games.

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They are the first seed in the Eastern Conference and had the best record in the NBA (64-18).

As for the Pacers, they beat the New York Knicks in the second round (in seven games).

Whoever wins the series will advance to the NBA Finals and face off against either the Dallas Mavericks or the Minnesota Timberwolves. 

That series will begin on Wednesday evening in Minnesota.

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Apr 11, 2024; Boston, Massachusetts, USA;  Boston Celtics center Kristaps Porzingis (8) dunks

Apr 11, 2024; Boston, Massachusetts, USA; Boston Celtics center Kristaps Porzingis (8) dunks / Bob DeChiara-USA TODAY Sports

Porzingis is in his ninth season in the NBA and has also spent time with the Wizards, Mavs and Knicks.





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No. 1 Taunton keeps rolling

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No. 1 Taunton keeps rolling


TAUNTON – Taunton once again showed why they are the team to beat in Div. 1 as well as the Hockomock League with yet another impressive victory at home Monday night.

After battling early, Texas Tech commit Sam Lincoln and the Tigers had more than enough to blank King Philip 4-0 at Jack Tripp Field to win the Hockomock Kelley-Rex outright.

“King Philip is always a tough team competition for us, so to come out on top just solidifies that the girls are working hard and to keep pushing” said Tigers coach Michelle Raposo about the win. “They never let things get them down or some adversity to bother them. It’s great to come out on top.”

It was Lincoln who battled through a pair of runners in the first to keep King Philip (16-3) off the board as she struck out a pair in the frame.

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She then hit a batter each in the second and third before settling in and retiring the final 12 batters, including striking out eight of the final nine for a total of 14.

“She is working with a new catcher and they’re still trying to work out the kinks of that,” Raposo said about the early innings with Aniyah Bailey catching. “A lot of her curveballs, the outside pitches, she’s not getting those calls. So, we are working on making the adjustments catching and trying to get a little more of those calls outside.”

Taunton (17-0) got on the board first as junior Brooke Aldrich led off with a double and scored on a King Philip error to make it 1-0 after four.

The Tigers weren’t done as they got three more runs in the fifth as Bailey cranked a two-run double to score sophomore Mia Torres and freshman Bella Bourque to push the lead to 3-0. Bailey scored one batter later on a hit for Aldrich.

“It felt great,” Lincoln said about getting those additional runs of support. “Only one run is not much, to be honest. One hit could score a run. So, having the extra runs just made me feel ten times more confident.”

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Next up, Taunton will host Tewksbury on Wednesday at 6:30 p.m. King Philip will be at Foxboro Wednesday at 3:45 p.m.



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