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Three women — ages 41, 55 and 64 — share their secrets to better health and longevity

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Three women — ages 41, 55 and 64 — share their secrets to better health and longevity

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For an increasing number of women over 40, age really is just a number.

It may not be possible to stop the passage of time — but certain healthy habits can help slow down biological age, experts say.

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“As we age, our abilities to perform certain physical and cognitive tasks decline, while our risks for disease and ultimately death increase,” Chris Mirabile, CEO and founder of NOVOS, a longevity supplements company in New York, told Fox News Digital.

“Although these changes are correlated with chronological age, biological age is a more accurate predictor, because it looks at individuals and how well – or poorly – they are aging.”

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If a 40-year-old woman has a biological age of 35, it implies that she is biologically in the same place as an average 35-year-old, Mirabile said – which means a significant reduction in risk for disease and death, plus an increased capacity for activities associated with a high quality of life.

Left to right, Julie Gibson Clark, Amy Hardison and Lil Eskey shared the lifestyle habits that help them slow down biological aging. (James Lee; Amy Hardison; Lil Eskey)

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For Women’s Health Month, three mothers at three different stages of life shared how they are defying age through simple lifestyle practices and interventions.

The women all participated in a six-month-long trial of NOVOS Core and Boost, supplements that are designed to slow down the aging process. Over the course of the study, they took three epigenetic tests, which analyzed DNA via a small blood sample to measure their “pace of aging.”

Lil Eskey, 41 years old, still has young kids

Lil Eskey, 41, is a stay-at-home mom and former fitness instructor in Phoenix, Arizona.

Growing up, she frequently had allergies and a constant sore throat. 

“The way that my mom handled it was to put me on antibiotics so many times when I was a kid,” she told Fox News Digital. 

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Lil Eskey, 41, pictured with her son, is a stay-at-home mom and former fitness instructor in Phoenix, Arizona. Maintaining a more youthful energy level is important to Eskey, as she is still raising young children. (Lil Eskey)

“I also had gut issues most of my life, so my path into health and wellness stemmed from trying to figure out what was going on with my body.”

Prioritizing her sleep is the biggest thing Eskey does for her health, she told Fox News Digital. 

“Good sleep is so underrated,” she said.

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“Having a consistent bedtime and wake-up time is so important for overall wellness. Everything works so much better when you’re well-rested, including any stressors in your life or anything going on with the mind.”

Eskey also tries to incorporate movement into her life wherever possible. 

“When my son goes to preschool, I pull him on a bike trailer. The same goes for anything that’s a few miles away, like grocery shopping.”

“I want to be completely present for my kids and maintain a level of energy and vitality in life.”

After dinner, the family often goes out on bike rides or jumps on the trampoline. 

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“We do anything to make it fun,” she said.

When it comes to mental health, Eskey has made the decision not to use social media.

Pictured on a hike, Eskey said she incorporates movement into her life wherever possible.  (Lil Eskey)

“I hear about anything that’s super important, and I’ll check the news occasionally to see what information I need, but to me, social media just seems like an additional stressor on the body,” she said. 

Eskey and her family often experiment with different health practices, she said. 

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“I listen to different podcasts on health and fitness to hear about new science or new ideas, and then we’ll test it out to see what works,” she said. 

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“For example, I realized I feel way better when I have a couple of hours between having my last meal and going to bed.”

She’s also experimented with using a continuous glucose monitor to track her blood sugar.

“We’re always just doing different experimental things to see what makes the biggest change,” Eskey said.

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Prioritizing her sleep is the biggest thing Eskey does for her health, she told Fox News Digital. “Good sleep is so underrated,” she said. (Photo Illustration by Ute Grabowsky/Photothek via Getty Images)

She has also been using anti-aging supplements from NOVOS. During the course of the study, Eskey’s biological pace of aging was reduced from .99 to .77.

“The time we’re here on this earth doesn’t always have to reflect the cumulative stress on our bodies. Rather, it’s stress that causes aging,” she said. 

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“It’s more important now than ever, with all the toxins and stressors we’re facing.”

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Maintaining a more youthful energy level is important to Eskey, as she is still raising young children, she said.

“The biggest thing is being able to keep up with my kids and be totally active,” Eskey said.  (Lil Eskey)

“The biggest thing is being able to keep up with my kids and be totally active,” she said. 

“When my kids want to play at the park, it’s important to me that I’m not just sitting on the bench watching them. I want to be completely present for my kids and maintain a level of energy and vitality in life.”

Julie Gibson Clark, 55 years old, focuses on movement

A recruiter who lives in Phoenix, Arizona, Julie Gibson Clark said she focuses on seven key areas to help slow down biological aging.

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The first is movement, both strength and cardio. “I focus on full-body strength training twice per week and a mix of zone 2 and Vo2Max training the rest of the week,” she told Fox News Digital.

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In her diet, Clark focuses heavily on veggies.

“I mix cooked greens and veggies, about 1 pound total every day,” she said. “I started small (about 4 ounces) and added about 1 ounce per week.”

Clark also prioritizes 90 to 100 grams of healthy protein each day: a mix of vegan protein, collagen and healthy, pasture-raised meats and eggs.

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Julie Gibson Clark, a recruiter who lives in Phoenix, Arizona, said she focuses on seven key areas to help slow down biological aging. (Julie Gibson Clark)

Sleep is also a big priority for Clark. “It’s hard to perform well at anything without proper sleep,” she told Fox News Digital.

Saunas and cold showers are another part of Clark’s regular routine. “This is my natural antidepressant and helps with focus during the day,” she said. “For anyone struggling with low mood or stressful times, I highly recommend trying this.”

Clark also began meditating in 2019, which she described as “a game-changer for stress and sleep.” 

“I like to think of longevity practices like a braid with three strands — exercise, eating right and prioritizing sleep.”

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“Twenty minutes every afternoon improves my sleep and allows me to recalibrate stress levels during the day,” she said.

Clark also takes NOVOS supplements, which she credits with increasing her energy levels and slowing her pace of aging by 8%, according to the study results.

“When you start moving, you’ll likely be more motivated to eat well, and your sleep will be better. When you sleep, it’s easier to stay on track with your diet and fitness plans,” Clark said. “They all work together.” (James Lee)

“I like to think of longevity practices like a braid with three strands — exercise, eating right and prioritizing sleep,” she told Fox News Digital. “And there’s an extra colorful strand in there: supplements. Each of these works together to help the others.”

She added, “When you start moving, you’ll likely be more motivated to eat well, and your sleep will be better. When you sleep, it’s easier to stay on track with your diet and fitness plans. They all work together.”

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Clark said she adheres to the motto, “It’s not the years in your life, but the life in your years.”

“I want all the years I have to be full of mobility, vibrance and vitality.”

Amy Hardison, 64 years old, makes exercising fun

A writer and grandmother of 11 in Mesa, Arizona, Amy Hardison has always had consistent health and exercise habits.

“I have exercised aerobically an hour a day, six days a week for 50 years and have rarely missed a day,” she told Fox News Digital. 

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“I always listen to an audiobook while exercising, making it even more fun.”

Amy Hardison’s favorite exercises include swimming and working out on the elliptical. “I love working out at home — other people love going to a gym and having a trainer. Do whatever works for you and then do it consistently,” she advised. (Amy Hardison)

Hardison’s favorite exercises include swimming and working out on the elliptical. 

“I love working out at home — other people love going to a gym and having a trainer. Do whatever works for you and then do it consistently,” she advised.

Regarding nutrition and exercise, Hardison’s philosophy is to find something you love that you can stick with long-term. 

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“Aging will take you places you have never been.”

“Some people totally cut out sugar from their diet, often because they tend to eat too much once they start,” she said. “Others, like me, eat small amounts each day.”

Hardison had never been into vitamins and supplements until she got involved in the NOVOS study.

“I really liked that the study included bloodwork at the beginning, middle and end of the year-long trial,” she said. 

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“My bloodwork revealed that at the beginning of the study, I was aging at .86 biological years for every chronological year.  At the end of the study, I was aging at .74. That is compelling empirical data.”

Although Hardison does what she can to stay physically healthy and mentally sharp, she acknowledges that there is a limit to what she can control. 

“Life is to be lived and enjoyed,” said Hardison, pictured hiking with her husband. (Amy Hardison)

“There is even a limit to how much I am willing to invest in longevity,” she said. “Life is to be lived and enjoyed.”

“Aging will take you places you have never been,” Hardison continued. 

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“There is so much to learn and experience. Embrace the normal and natural decline with humor and perspective. Thank your body for taking you on the journey.”

A biohacker’s 5 quick tips for healthy aging

Melanie Avalon, health influencer, entrepreneur and host of The Intermittent Fasting Podcast and “The Melanie Avalon Biohacking Podcast,” agreed that women can take proactive steps to slow their pace of aging.

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“The ever-growing online bloodwork and genetic platforms allow women access to personal data, providing a deeper view of their aging on a cellular level, including monitoring their biological age, which may differ from their chronological age,” she told Fox News Digital. 

“Women can then make dietary and lifestyle choices to optimize these markers.”

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1. Optimize sleep

One of the biggest issues aging women experience is restless sleep, often characterized by tossing, turning and hot flashes, according to Avalon.

One of the biggest issues aging women experience is restless sleep, often characterized by tossing, turning and hot flashes, according to Avalon. (iStock)

“Women can implement a ‘sleep sanctuary’ to best support a restorative night, including sticking to a consistent wind-down routine and sleep schedule, in a cool, dark environment,” she advised.

Using a cooling mattress, avoiding late-night blue light exposure, and finding the optimal sleep position are some ways women can achieve better sleep quality, Avalon advised.

2. Seek hormonal support as needed

“Women often dread the perimenopausal years for their seemingly inevitable rollercoaster of hormonal issues,” Avalon said.

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“Women can support healthy hormonal levels and natural transitions into the menopausal years by nourishing their bodies with micronutrient-rich whole foods, getting ample sleep, addressing stress levels, and reducing their exposure to toxins.”

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For some women, hormone replacement therapy may be an option.

“Many women may find that the benefits outweigh the risks,” Avalon noted.

3. Optimize muscle mass

Maintaining muscle mass is crucial for healthy aging, according to Avalon. 

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“Declines in muscle mass and strength are intrinsically tied to mortality, playing a causative role in falls and metabolic issues,” she said. 

The maintenance of muscle mass is crucial for healthy aging, according to one expert. (iStock)

“Aging typically leads to reduced muscle protein synthesis,” Avalon noted.

“Women should pay careful attention to getting ample protein as they age, with a particular focus on the amino acid leucine, which stimulates muscle protein synthesis.” 

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Aging women should aim for a gram of protein per pound of body weight, Avalon recommended. 

“Women can also engage in strength training to further support muscle growth and maintenance,” she added.

4. Monitor essential markers

“Aging women should embrace the agency to take their health into their own hands,” Avalon said.

Women should work with conventional doctors to regularly check key health metrics, such as blood pressure, blood sugar levels, cholesterol and bone density, along with other markers of disease, an expert advised. (iStock)

She recommends working with conventional doctors to regularly check key health metrics, such as blood pressure, blood sugar levels, cholesterol and bone density, along with other markers of disease.

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5. Achieve proper glycemic control

Poor glycemic control is linked to a myriad of degenerative diseases, from prediabetes and diabetes to cardiovascular disease and cognitive decline, according to Avalon. 

“Aging women can implement an unprocessed, whole-food-based diet, low to moderate in carbs, depending on their tolerance,” she said. 

Women can also opt to wear a continuous glucose monitor (CGM) to monitor their blood sugar levels.

For more Health articles, visit www.foxnews.com/health.

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She Started Her Own Treadmill Workout for Weight Loss—and Shed 270 Pounds!

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She Started Her Own Treadmill Workout for Weight Loss—and Shed 270 Pounds!


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New drug approach offers hope for patients with recurrent aggressive cancers

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New drug approach offers hope for patients with recurrent aggressive cancers

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A new treatment for endometrial cancer demonstrated strong potential in a Phase 3 clinical trial.

Drugmaker Merck announced Monday that the investigational drug sacituzumab tirumotecan (sac-TMT) met its “primary endpoints” of overall survival and progression-free survival in patients with advanced or recurrent endometrial cancer.

The TroFuse-005 trial is the first global Phase 3 trial to “demonstrate statistically significant improvement” in survival compared to chemotherapy in these patients, according to a Merck press release.

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This was also the first and only antibody-drug conjugate (ADC) to achieve such a result for endometrial cancer patients in this setting, the researchers stated.

An ADC is a targeted cancer therapy that delivers more of the drug to tumor cells while limiting damage to healthy cells.

The investigational drug, sac-TMT, is administered every two weeks via IV infusion. (iStock)

The trial involved 776 patients with endometrial cancer whose disease worsened after receiving both platinum chemotherapy and immunotherapy.

The patients were randomly assigned sac-TMT, administered every two weeks, or a treatment of the physician’s choice, including doxorubin or paclitaxel chemotherapy. The patients were aware of which treatment they were receiving.

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Those receiving sac-TMT showed “clinically meaningful improvement” in their disease state compared to the treatment of physician’s choice, the researchers found.

The study also met response rate benchmarks and exhibited similar side effects to earlier studies of the same drug, Merck reported.

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The drugmaker did not disclose any statistics on exact survival benefit, response rate, side effect rates or other details, but the researchers aim to present this Phase 3 data at an upcoming medical meeting.

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The drug “may be able to address a critical unmet need for certain patients with advanced endometrial cancer,” said the lead researcher (not pictured). (iStock)

Dr. Domenica Lorusso, the study’s global lead investigator and professor of obstetrics and gynecology at Humanitas University and Humanitas San Pio X in Milan, wrote in a press release that these results show sac-TMT “may be able to address a critical unmet need for certain patients with advanced endometrial cancer, one of the only cancers increasing in both incidence and mortality worldwide.”

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“Despite recent advances, patients whose disease progresses following treatment with platinum and immunotherapy are urgently in need of new options, and these findings show for the first time that a TROP2 ADC may be an effective option in this setting,” she added.

Dr. Brian Slomovitz, co-director of gynecologic oncology at Mount Sinai and an investigator on this trial, reflected on the study findings during an interview with Fox News Digital.

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“Unlike many other cancers that we are treating, the number of endometrial cancers and the number of deaths due to endometrial cancers are on the rise,” Slomovitz noted.

“In the United States, the number of deaths due to endometrial cancer has surpassed the number of deaths due to ovarian cancer, [making it] the deadliest of all gynecologic malignancies.”

Endometrial cancer has become “the deadliest of all gynecologic malignancies,” one doctor shared. (iStock)

Despite recent advancements introducing immunotherapy as the standard of care, “better treatment options” for patients with recurrent disease “remains an unmet need,” Slomovitz commented.

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“If the full data confirm this announcement, the key questions will be the magnitude of the survival benefit and the toxicity profile — those will define sac-TMT’s role,” he said. 

“But an overall survival improvement in recurrent disease is a real, meaningful result for patients and their families, not just a statistical one.”

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Could Ebola spread to the US? WHO emergency sparks fears after American infected in Congo

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The World Health Organization has declared an international public health emergency as a growing Ebola outbreak in Central Africa sparks concern that the deadly virus could spread beyond the region — including into the United States.

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The outbreak has been linked to dozens of suspected deaths in the Democratic Republic of Congo (DRC) and neighboring Uganda.

Ebola is a zoonotic, viral disease that is rare but life-threatening, according to Cleveland Clinic. Outbreaks typically develop in areas of Africa, starting in species like antelope, fruit bats and nonhuman primates.

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There are four different Ebola strains, also known as orthoebolaviruses. Bundibugyo virus is the strain that has been detected in the DRC outbreak.

While the outbreak does not meet the criteria for a pandemic emergency, U.S. officials are warning Americans not to visit the area, escalating the State Department travel advisory from a Level 3 to Level 4 on Sunday.

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A visitor washes his hands at a checkpoint before entering Kyeshero Hospital in Goma, Democratic Republic of Congo, on May 18, 2026, as part of Ebola prevention measures following a reported case in the city. (Jospin Mwisha/AFP)

One American tested positive for Ebola on May 17 while working in Congo and is being transported to Germany for treatment with other Americans who are high-risk contacts, according to the Centers for Disease Control and Prevention.

As of May 18, there have been 11 confirmed and 336 suspected cases, including 88 deaths in the DRC.

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“This is a rapidly evolving situation, and case counts are subject to change,” the CDC noted.

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While no cases have been detected in the U.S., there is a possibility that it could make its way into American territory, posing a threat to public health.

“This virus is transmitted only person-to-person via infected blood and body fluids from symptomatic people.”

Dr. Jacob Glanville, a leading immunologist at Centivax in San Francisco, which is developing a universal flu vaccine, spoke with Fox News Digital about the potential spread of Ebola into the U.S.

The doctor noted that the virus has a two- to 21-day incubation period, during which an infected person can show no symptoms and the infection cannot be detected by tests.

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“It is thus possible for Ebola to move across international borders silently, bypassing screening,” he said.

“Some travel restrictions from the affected area have been put in place to limit this risk, although as this outbreak was spreading silently for months, it is possible that an infected traveler had come to the U.S. in the past 21 days from the affected areas prior to the travel restrictions.”

A visitor washes his hands at a checkpoint outside Kyeshero Hospital in Goma, Democratic Republic of Congo, on May 18, 2026, as part of Ebola prevention measures following the first reported case in the city. (Jospin Mwisha/AFP)

Glanville noted that while the outbreak is “growing rapidly,” one week ago there were fewer than 500 global cases.

“Thus, the chance of an infected traveler having come to the U.S. remains quite low for the time being,” he said.

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Dr. Robert H. Hopkins, Jr., medical director of the National Foundation for Infectious Diseases, agreed that the threat to American communities remains low.

“The viruses that cause Ebola pose a very small risk, even to travelers to areas with outbreaks,” the Arkansas-based expert told Fox News Digital. “This virus is transmitted only person-to-person via infected blood and body fluids from symptomatic people, and rarely from infected animals.”

Those who believe they have been exposed to Ebola should seek medical attention immediately, experts advise. (iStock)

Ebola spreads through direct contact with infected blood, bodily fluids or remains of infected people or animals, including fluids such as saliva and sweat, according to Hopkins.

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Cleveland Clinic notes that it is “very unlikely” for Ebola to be an airborne infection.

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The virus starts with flu-like symptoms, including fever, chills, fatigue, headache, muscle pain, vomiting/diarrhea and loss of appetite. Other signs may include a rash or spots of blood under the skin, hiccups, bruising and red, bloodshot eyes.

As the disease is a type of viral hemorrhagic fever, it causes damage to the blood vessels and can lead to more serious symptoms, including severe bleeding or hemorrhaging, neurological disorders and severe vomiting.

Health workers dressed in protective gear begin their shift at an Ebola treatment center in Beni, Congo, on July 16, 2019. (Jerome Delay/AP)

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For those who have traveled to the outbreak area, Hopkins recommends monitoring for symptoms for three weeks after departing and seeking immediate care if symptoms develop.

Treatments are available, along with a vaccine that can help protect high-risk individuals and prevent further spread, according to healthcare professionals.

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Avoiding contact with blood, body fluids, and sick or deceased people and animals is “highly effective in the prevention of Ebola transmission,” Hopkins advised.

“If contact is required, high-quality personal protective equipment is recommended before contact with potentially infectious people and/or materials,” he added.

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Fox News Digital’s Michael Sinkewicz and Andrea Margolis contributed to this report.

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