Health
Why cancer is hitting the Midwest harder than anywhere else in America
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While the rest of the country’s cancer rates are falling, those in Iowa, Nebraska, Illinois, Minnesota, Indiana and Kansas — known as the Corn Belt — are rising at an alarming rate, data shows.
The spike in America’s corn-producing states caught the attention of the University of Iowa’s Holden Comprehensive Cancer Center, which gathered a panel to investigate the trend.
One of the experts, Dr. Marian Neuhouser, a professor at the Fred Hutchinson Cancer Center in Seattle, served on the panel as an expert in nutrition and obesity.
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“The panel came about after they noticed that the trends for cancer incidence were increasing at a faster rate in Iowa than in other states,” Neuhouser told Fox News Digital.
A data analysis by The Washington Post based on federal health datasets found that the number of people diagnosed with cancer in the six Corn Belt states has outpaced the national average since the mid-2010s.
While the rest of the country’s cancer rates are falling, those in the Corn Belt states — Iowa, Nebraska, Illinois, Minnesota, Indiana and Kansas — are rising at an alarming rate. (iStock)
In 1999, cancer rates in the Midwest were on par with the national average. Now, among residents aged 15 to 49, those rates are about 5% higher, a pattern that began diverging in the 2000s and has steadily widened.
The Post based its findings on data from the National Cancer Institute and the Centers for Disease Control and Prevention, which track cancer incidence nationwide.
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The analysis compared rates from 1999 through 2022 using multi-year averages for Iowa and excluding 2020 due to pandemic disruptions.
Experts probe causes
Neuhouser noted that some of the increases involve cancers that are preventable or detectable through screening.
Researchers are examining both environmental and lifestyle factors that could be driving the increase.
A panel of experts convened in Iowa after more numbers came out about the alarming spike in cancer rates. (iStock)
Outdoor UV exposure and high rates of binge drinking could be contributors, according to the Iowa Cancer Registry, part of the National Institutes of Health’s surveillance network.
Iowa’s Environmental Health Sciences Research Center has described the state as a “hot spot for environmental exposures to carcinogenic agents.”
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The soil and groundwater in the region reportedly contain some of the nation’s highest levels of natural radon and nitrate, largely because of fertilizer use in farming. Both substances have been linked to high risks of lung and gastrointestinal cancers.
Meanwhile, the widespread application of pesticides and herbicides, including glyphosate, continues to generate debate among scientists and regulators.
Where fields once symbolized abundance, they now raise questions about how the chemicals used to maintain them could affect people’s health. (iStock)
Risk of chemical exposure
Dr. Anne McTiernan, professor of epidemiology at the Fred Hutchinson Cancer Center in Seattle, has analyzed decades of research on glyphosate and cancer risk.
“Glyphosate, a broad-spectrum herbicide, has been used in the U.S. for decades and is reported to be the most widely used pesticide globally,” she told Fox News Digital.
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The World Health Organization’s International Agency for Research on Cancer classified glyphosate as “a 2A carcinogen (“probably carcinogenic to humans”), which is the second-highest grade of carcinogen, according to McTiernan.
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Her review of studies through 2025 found that people with long-term, high exposure to glyphosate, such as those working on farms, had a roughly 40% higher risk of developing non-Hodgkin lymphoma compared to those who were never exposed.
Researchers warn that the causes of cancer spikes in the Corn Belt may lie in decades of invisible exposure. (iStock)
This level of increased risk, combined with lab evidence that glyphosate can damage DNA and cause cellular stress, is considered strong enough to support a causal link, according to the expert.
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Role of obesity and alcohol
Lifestyle factors are also compounding risk. Per CDC data, about 21% of Iowa adults report heavy drinking or binge drinking, compared to roughly 17% nationally.
The Iowa Department of Health and Human Services reports that about 35% of adults in the state are classified as obese, placing it among 19 states with obesity prevalence at or above that level. Nationwide, the CDC reports an adult obesity rate of roughly 40%.
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Neuhouser noted that 13 separate cancers are linked to obesity.
“Everyone would like to be able to narrow down cancer risk … to one exposure, but cancer is so complex that it’s usually several factors working together,” she said.
Health
Former reality star opens up about new diagnosis after years-long health ordeal
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A former “Real Housewives of Beverly Hills” star is speaking out about a fresh wave of health issues.
Brandi Glanville, 53, has been speaking publicly about ongoing swelling, lumps and paralysis of her face since 2023.
At the time, the reality star shared that she believed she had been infected with a parasite during a trip to Morocco, Fox News Digital previously reported.
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After the initial diagnosis, she suspected she contracted a parasite in Morocco and said she could feel it moving within her face.
Brandi Glanville attends the grand opening of Beverly Hills Rejuvenation Clinic West Hollywood in West Hollywood, Calif., on April 25, 2024. (Paul Archuleta/Getty Images)
Glanville was first diagnosed with stress-induced angioedema, a sudden swelling of the deeper layers of the skin and mucous membranes, according to Cleveland Clinic.
Angioedema “is a reaction similar to hives that affects deeper layers of the skin. It can appear with hives or alone,” Mayo Clinic states.
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Most recently, in a June 18 episode of her podcast “Brandi Glanville Unfiltered,” Glanville revealed that doctors discovered a “benign tumor” in one of her facial lymph nodes.
The reality star, who has previously speculated that a parasite may be contributing to her facial symptoms, said the finding could help explain the swelling and fluid buildup she has experienced and noted that she has had a lump in her face for “years.”
Brandi Glanville, 53, has been speaking publicly about ongoing swelling, lumps and paralysis of her face since 2023. (Mega/GC Images)
“I don’t know what’s wrong with me, guys. I thought I was fixed, and then it happened again and now it’s sinking in again,” Glanville said in another June podcast.
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“It could be why the fluid is going around my face and why I’m having a hard time,” she added.
While benign tumors of the face have been known to arise from fat tissue, blood vessels, skin structures, salivary glands or lymphatic tissue, Glanville has not publicly disclosed the specific type of diagnosis she received.
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Prior to learning of the tumor, Glanville said she saw dozens of doctors and spent over $100,000 trying to pinpoint the source of the issue.
Brandi Glanville shares images of painful facial burns caused by Nair hair removal cream in a viral TikTok video. (Brandi Glanville/TikTok)
The reality star emphasized that the tumor is “not cancerous.”
“I haven’t had a face lift yet!” she added.
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Glanville also said she suspected her ruptured breast implants could have played a role in her health issues, claiming the leaking silicone had clogged her lymph nodes.
Fox News Digital reached out to Glanville for comment.
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Health
One common type of fat may increase diabetes risk, while another helps fight it
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A new review suggests that the type of fat you eat may affect your risk of developing type 2 diabetes.
Saturated fats rich in palmitic acid – the most common saturated fatty acid in U.S. foods – appear to make it harder for the body to respond to insulin.
Meanwhile, monounsaturated fats rich in oleic acid — such as those found in olive oil — may help protect against insulin resistance, the review concluded.
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“Palmitic acid is found in meats, dairy products, cocoa butter and in the form of palm oil in foods, including margarine, cereal, sweets, baked goods and fast foods,” Tanya Freirich, a registered dietitian nutritionist in Charlotte, North Carolina, told Fox News Digital. She was not involved in the review.
“Oleic acid, on the other hand, is in higher concentration in foods like olive oil, canola oil, nuts, sunflower seeds, eggs, olive, avocados and also in meats (beef, chicken, pork), milk, cheese and pasta.”
Saturated fats rich in palmitic acid – the most common saturated fatty acid in U.S. foods – appear to make it harder for the body to respond to insulin. (iStock)
The review, which was published in the journal Trends in Endocrinology & Metabolism, was led by researchers from the University of Barcelona and the CIBER Area for Diabetes and Associated Metabolic Diseases (CIBERDEM) in Spain.
The findings suggest that fat quality may be more important than total fat quantity when it comes to metabolic health and diabetes risk.
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This appears to support the idea that diets rich in monounsaturated fats, such as the Mediterranean diet, may contribute to lower rates of type 2 diabetes.
“Palmitic acid promotes several molecular processes that impair insulin action,” study investigator Dr. Manuel Vázquez-Carrera, from the Department of Pharmacology, Toxicology and Therapeutic Chemistry at the University of Barcelona, told Fox News Digital.
“Palmitic acid is found in meats, dairy products, cocoa butter and in the form of palm oil in foods, including margarine, cereal, sweets, baked goods and fast foods,” a nutritionist said. (iStock)
Too much palmitic acid can cause harmful fat byproducts to build up in the body, which can impair the body’s ability to respond to insulin, he warned. This makes it harder to control blood sugar and increases the risk of insulin resistance and type 2 diabetes.
“It also promotes inflammation, oxidative stress, mitochondrial dysfunction and cellular stress responses, which contribute to insulin resistance and β-cell dysfunction,” Vázquez-Carrera added.
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By contrast, oleic acid – a hallmark of the Mediterranean diet – does not have these harmful effects, according to the researcher.
“In fact, oleic acid can counteract many of the detrimental effects triggered by palmitic acid, by promoting the storage of fatty acids in relatively inert triglycerides, preserving mitochondrial function and reducing inflammation,” he said.
“All sources of fat in our diet contain a mix of saturated and unsaturated fatty acids.”
Freirich confirmed that the review is consistent with previous research supporting the use of olive oil in the diet for metabolic benefits.
“Also confirming previous research, the consumption of saturated fats is associated with some negative metabolic changes,” she told Fox News Digital.
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Given the complexity of foods and diets, there is an overlap between foods that contain both types of fatty acids, the nutritionist noted.
“Palmitic acid and oleic acid can both be found in olive oil, baked goods and fast foods, in differing amounts,” she said. “All sources of fat in our diet contain a mix of saturated and unsaturated fatty acids.”
Study limitations
Vázquez-Carrera noted that these findings come from a review of numerous experimental, clinical and epidemiological studies rather than a single clinical trial.
“One important limitation is that much of the mechanistic evidence comes from cell culture and animal studies,” he said.
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“Although these studies provide valuable insights into how specific fatty acids affect insulin signaling, further human intervention studies are needed to confirm the extent to which these mechanisms operate in everyday dietary settings.”
In addition, many of the human studies in the review relied on self-reported dietary intake, which can introduce inaccuracies.
Type 2 diabetes develops over many years, with genetics, lifestyle and environmental factors all playing a role, the researcher noted. (iStock)
“Another challenge is that people consume foods containing complex mixtures of fatty acids and bioactive compounds rather than isolated fatty acids,” Vázquez-Carrera added. “Therefore, it remains difficult to fully disentangle the specific contribution of individual fatty acids in free-living populations.”
Nutritional recommendations
The review’s findings appear to support current dietary recommendations that emphasize replacing part of the saturated fat intake with unsaturated fats, according to Vázquez-Carrera.
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“This means favoring dietary patterns rich in foods such as extra-virgin olive oil, nuts, seeds, legumes, vegetables, fruits and fish, while limiting excessive consumption of foods rich in saturated fats, especially highly processed foods,” he advised.
The review does not suggest that a single nutrient alone determines diabetes risk, the researcher pointed out.
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“Rather, maintaining a healthy body weight, engaging in regular physical activity and following an overall healthy dietary pattern, such as the Mediterranean diet, remain fundamental strategies for preventing insulin resistance and type 2 diabetes.”
Type 2 diabetes develops over many years, with genetics, lifestyle and environmental factors all playing a role, Vázquez-Carrera noted.
Improving the quality of dietary fat intake could prove to be an effective strategy for reducing type 2 diabetes risk, the review suggests. (iStock)
“Future research should move beyond simply classifying fats as ‘good’ or ‘bad’ and instead focus on understanding how specific fatty acids, their dietary sources and their interactions within whole dietary patterns affect metabolic health,” he said.
Improving the quality of dietary fat intake could prove to be an effective strategy for reducing type 2 diabetes risk, according to the researcher.
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“A simple takeaway for consumers is to swap out foods high in saturated fat more often with foods rich in heart-healthy fats, like olive oil, nuts and avocados, to better support blood sugar and metabolic health,” advised New Jersey-based registered dietitian Erin Palinski-Wade, who was also not involved in the review.
Anyone at a higher risk for type 2 diabetes should consult a healthcare provider for personalized guidance on nutrition, exercise and other preventive measures, experts say.
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