Health
Where you live could shape your risk of cancer mortality, study suggests
Marriage linked to lower cancer risk, study finds
Dr. Namrata Vijayvergia discusses a new study indicating a lower cancer risk for married adults due to social support and healthier lifestyles and the correlation between gardening and cognitive health.
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While U.S. cancer deaths have been falling over the past couple of decades, certain parts of the country are seeing less improvement in those numbers.
New research published in the British Journal of Cancer assessed the differences in cancer mortality improvements across the country.
Researchers at Mississippi State’s Social Science Research Center, along with scientists at Oak Ridge National Laboratory, analyzed death certificates between 1981 and 2019 across nearly 3,000 U.S. counties.
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The data was drawn from Wide-Ranging Online Data for Epidemiologic Research (WONDER), which is operated by the CDC. More than 21.3 million cancer deaths were included in the records.
Overall, U.S. cancer mortality has declined by about 32% between 1991 and 2019, but not all areas experienced that level of improvement.
While U.S. cancer deaths have been falling over the past couple of decades, certain parts of the country are seeing less improvement. (iStock)
The highest rates of mortality decline and the biggest drop in excess deaths were seen in urban, coastal and higher-income counties, according to the study. Rural and lower-income counties had smaller declines in mortality.
“In a complex nation such as the U.S., we should not be too surprised that there are large differences in health outcomes shaped by the diversity and variety of local regions and groups,” Arthur G. Cosby, the study’s lead author, told Fox News Digital. He is a Giles Distinguished Professor Emeritus at Mississippi State.
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“Cancer improvement over the last few decades certainly aligns with this perspective,” he said.
The gap appeared to widen over time, researchers noted. By 2019, the top 10% highest-income counties had a roughly seven times greater mortality improvement than the lowest-income counties.
The highest rates of mortality decline and the biggest drop in excess deaths were seen in urban, coastal and higher-income counties, according to the study. (iStock)
The large urban centers along both the Atlantic and Pacific coasts consistently had among the highest rates of cancer improvement, according to Cosby. Rural and smaller cities in the interior of the U.S. often had much lower rates.
“The magnitude of the mortality differences between coastal and inland regions, [and] the large differences between places with different income levels and rural/urban places, were larger than I anticipated,” Cosby said.
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“The link between improving health and increasing disparities is poorly understood. I am pursuing that question now,” he added.
The researchers pointed to several factors that could contribute to the declines in cancer mortality. These included a decline in tobacco use and improved cancer screenings and treatments.
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“Wealthy, metropolitan New York City has been aggressive in instituting tobacco control measures, and the results show,” Cosby noted. “Manhattan had a lung cancer rate of 49 per 100,000 in 1991. By 2019, it cut its rate to 19.6 — a 60% reduction.”
Rural and smaller cities in the interior of the U.S. often had much lower mortality rates. (iStock)
Dr. Marc Siegel, Fox News senior medical analyst, agreed that more aggressive preventive measures targeting smoking and alcohol use likely played a role in the sharper mortality decline in urban, affluent areas.
“More aggressive screening campaigns, including at major medical centers, can diagnose pre-cancers or cancers earlier,” Siegel, who was not involved in the study, told Fox News Digital.
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A focus on improved lifestyle habits and less exposure to environmental toxins could also play a role, he added.
The study had some limitations, as noted by the authors.
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Because the research was conducted at the county level, the results may not apply at the individual level.
Also, unmeasured factors such as lifestyle behaviors and access to healthcare could impact mortality.
The highest rates of mortality decline and the biggest drop in excess deaths were seen in urban, coastal and higher-income counties, according to the study. (iStock)
“There are many limitations associated with the use of death certificates in research, such as accuracy of cause of death, possible multiple causes and changes in medical explanation for death over time,” Cosby told Fox News Digital.
Based on the findings, the researchers are calling for more studies that take into account the significant variations that exist across the country.
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“The varying speed of adoption of life-saving interventions between geographic places may produce increasing disparities,” Cosby said. “It is possible to have a situation where nearly all places are improving their cancer mortality, but at much different rates.”
Health
Loneliness may be silently eroding your memory, new research reveals
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Feeling lonely may take a toll on older adults’ memory — but it may not speed up cognitive decline, according to a new study.
Researchers from Colombia, Spain and Sweden analyzed data from more than 10,000 adults ages 65 to 94 across 12 European countries and found those who reported higher levels of loneliness did worse on memory tests at the start of the study, according to research published this month in the journal Aging & Mental Health.
Over a seven-year period, however, memory decline occurred at a similar rate regardless of how lonely participants felt.
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“The finding that loneliness significantly impacted memory, but not the speed of decline in memory over time was a surprising outcome,” lead author Dr. Luis Carlos Venegas-Sanabria of the School of Medicine and Health Sciences at the Universidad del Rosario said in a statement.
Loneliness may be linked to memory performance in older adults, a new study suggests. (iStock)
“It suggests that loneliness may play a more prominent role in the initial state of memory than in its progressive decline,” Venegas-Sanabria said, adding that the findings highlight the importance of addressing loneliness as a factor in cognitive performance.
The findings add to debate about whether loneliness contributes to dementia risk. While loneliness and social isolation are often considered risk factors for cognitive decline, research results have been mixed.
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The study looked at data from the long-running Survey of Health, Ageing and Retirement in Europe (SHARE), which tracked 10,217 older adults between 2012 and 2019. Participants were asked to recall words immediately and after a delay to measure memory performance.
Social isolation and loneliness could play a surprising role in cognitive health among seniors. (iStock)
Loneliness was assessed using three questions about how often participants felt isolated, left out or lacking companionship.
About 8% of participants reported high levels of loneliness at the outset. That group tended to be older, more likely to be female and more likely to have conditions such as depression.
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Researchers found that those with higher loneliness had lower scores on both immediate and delayed memory tests at baseline. Still, all groups — regardless of loneliness level — experienced similar declines in memory over time.
The results suggest loneliness may not directly accelerate the progression of memory loss, though it remains linked to poorer cognitive performance overall.
Researchers look at a brain scan at the National Institutes of Health in Bethesda, Maryland. (Saul Loeb/AFP/Getty Images)
Experts warn, however, that the findings should not be interpreted to mean loneliness is harmless.
“The finding that lonely older adults start with worse memory but don’t decline faster is actually the most interesting part of the paper, and I think it’s easy to misread,” said Jordan Weiss, Ph.D., a scientific advisor and aging expert at Assisted Living Magazine and a professor at NYU Grossman School of Medicine.
“It likely means loneliness does its damage earlier in life, well before people show up in a study like this at 65-plus,” Weiss told Fox News Digital.
By older age, long-term social patterns may already be established, making it harder to detect when the effects of loneliness first took hold, an aging expert says. (iStock)
He suggested that by older age, long-term social patterns may already be established, making it harder to detect when the effects of loneliness first took hold.
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“By the time you’re measuring someone in their late 60s, decades of social connection patterns are already baked in,” he said.
Weiss, who was not involved in the research, added that loneliness may coincide with other health conditions, and noted that participants who felt more isolated also had higher rates of depression, high-blood pressure and diabetes. The link, he said, may reflect a cluster of health risks rather than a direct cause.
“While they can go hand-in-hand, it’s not clear that loneliness contributes to dementia,” a psychotherapist says. (iStock)
Amy Morin, a Florida-based psychotherapist and author, said the findings reflect a broader pattern in research on loneliness and brain health, and that the relationship may be more complex than it appears.
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“The evidence shows there’s a link between loneliness and cognitive decline but there’s no direct evidence of a cause and effect relationship,” she said. “So while they can go hand-in-hand, it’s not clear that loneliness contributes to dementia.”
Morin added that loneliness, which can fluctuate, may not be the root of the problem, but rather a symptom of other underlying mental or physical health issues.
Researchers suggested screening for loneliness be incorporated into routine cognitive assessments as one way to support healthy aging. (iStock)
She said staying socially and mentally engaged is crucial for overall brain health.
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“It’s important to be proactive about social activities,” Morin said. “Joining a book club, having coffee with a friend, or attending faith-based services can be a powerful way to maintain connections in older age.”
The researchers also suggested screening for loneliness be incorporated into routine cognitive assessments as one way to support healthy aging.
Fox News Digital reached out to the researchers for comment.
Health
Eat More To Lose Weight? She Dropped 55 Pounds by Having 5 Meals a Day
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Health
Intermittent fasting’s real benefit may come after you start eating again
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Research continues to uncover new details on how fasting may help extend life.
A new study published in the journal Nature Communications investigated how intermittent fasting can boost longevity in small worms often used in aging research.
Researchers from the University of Texas Southwestern Medical Center in Dallas compared worms that were fed normally to those that underwent a 24-hour fast in early adulthood and were then fed again, according to a press release.
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The scientists measured a variety of factors, including stored fat, gene activity related to fat metabolism and lifespan.
The results showed that the life-boosting benefit did not depend on the fasting itself but on the body’s behavior after eating again.
Experts say sustainability is key when choosing a long-term weight-loss strategy. (iStock)
Study lead Peter Douglas, associate professor of molecular biology and a member of the Hamon Center for Regenerative Science and Medicine at UT Southwestern, suggested that these discoveries “shift the focus toward a neglected side of the metabolic coin – the re-feeding phase.”
“Our data suggest that the health-promoting effects of intermittent fasting are not merely a product of the fast itself, but are dependent on how the metabolic machinery recalibrates during the subsequent transition back to a fed state,” he said.
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“Our findings bridge a gap between lipid metabolism and aging research,” he added. “By targeting aging, the single greatest risk factor for human disease, we move beyond treating isolated conditions toward a preventive model of medicine that enhances quality of life for all individuals.”
Lauri Wright, director of nutrition programs at the University of South Florida’s College of Public Health, called this a “high-quality” study that adds an “important nuance to how we think about fasting and longevity.”
Intermittent fasting typically involves limiting meals to an eight-hour daily window or fasting every other day. (iStock)
The benefits of the refeeding phase after fasting were “especially interesting,” Wright, who was not involved in the study, told Fox News Digital.
“The researchers showed that longevity was linked to the body’s ability to turn off fat breakdown after fasting, allowing cells to restore energy balance,” she reiterated.
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“From a scientific standpoint, that’s a meaningful shift because it suggests fasting is not just about burning fat, but about metabolic flexibility.”
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Fasting may support longevity through triggering metabolic switching, enhancing cellular repair and stress resistance and improving markers like insulin sensitivity, research shows.
Limitations and cautions
Although this study provides “important insight” on the power of refeeding, Wright noted that the findings should be approached with caution, as the study was done on worms and cannot always be translated to humans.
“Additionally, it explains how a process might work in a controlled lab condition rather than real-world eating behaviors,” she added as a limitation. “Finally, the study is short-term and doesn’t give us the long-term translation on lifespan outcomes.”
The review found intermittent fasting was barely more effective than doing nothing, according to the study authors. (iStock)
Wright cautioned that fasting is “not a magic solution for longevity, and how you eat overall matters more than when you eat.”
“I advise, first and foremost, to focus on diet quality, including a variety of fruits and vegetables, healthy fats and minimally processed foods,” she said.
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For those who are considering fasting, it’s better to stick with a moderate plan — like a 12- to 14-hour overnight fast — rather than going to extremes, Wright said. After fasting, she recommends focusing on well-balanced meals.
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Several groups of people should be cautioned against fasting, according to Wright, including those with diabetes who are on insulin or hypoglycemic medications, those who are pregnant or breastfeeding, anyone with a history of eating disorders and older adults at risk of malnutrition.
Anyone considering intermittent fasting should consult with a doctor before starting.
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