Health
These 17 cancer types are more common in Gen X and millennials, as study notes 'alarming trend'
Certain types of cancers are more prevalent among Gen X and millennials, according to a new study led by the American Cancer Society (ACS).
The study, published in the journal The Lancet Public Health, analyzed data from over 23 million patients who were diagnosed with 34 different types of cancer over two decades.
The patients ranged in age from 25 to 84, representing multiple generations.
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Researchers found that the prevalence of small intestine cancer, kidney cancer and pancreatic cancer was two to three times higher in those born in 1990 than those born in 1955 for both males and females, and for liver cancer in females, according to an ACS press release.
Rates were also higher among younger groups for breast cancer (estrogen-receptor positive), uterine cancer, colorectal cancer, non-cardia gastric cancer, gallbladder cancer, ovarian cancer, testicular cancer, anal cancer in males and Kaposi sarcoma in males, the study found.
Other cancers that were more prevalent in younger groups included myeloma, leukemia, cardia gastric cancer, and non-HPV-associated oropharyngeal cancer (in women).
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Death rates also rose among younger groups for liver cancer (females), gallbladder cancer, uterine cancer, testicular cancer and colorectal cancer.
“These findings add to growing evidence of increased cancer risk in post-baby boomer generations, expanding on previous findings of early-onset colorectal cancer and a few obesity-associated cancers to encompass a broader range of cancer types,” said Dr. Hyuna Sung, lead author of the study and a senior principal scientist of surveillance and health equity science at the American Cancer Society, in the ACS release.
“Birth cohorts, groups of people classified by their birth year, share unique social, economic, political and climate environments, which affect their exposure to cancer risk factors during their crucial developmental years.”
While researchers have identified some cancer trends associated with certain age groups, they don’t yet have a clear explanation for why these rates are rising, Sung added.
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Cancer has historically been associated with aging, yet doctors have seen an “alarming trend” of surging cases among those under 50 years of age, according to Edward S. Kim, M.D., the physician-in-chief of City of Hope Orange County and vice physician-in-chief of City of Hope National Medical Center in California.
“It is vital that we identify the reasons behind this trend.”
“This latest trend indicating increases in early onset cancer is a paradigm shift,” Kim, who was not involved in the study, told Fox News Digital via email.
“It is vital that we identify the reasons behind this trend, educate the public, advance prevention and early diagnosis, and develop more effective treatments.”
There is “considerable evidence” pointing to environmental causes of early-onset cancers, according to Kim.
“We cannot deny that an extensive range of environmental factors have rapidly transformed in developed countries since the mid-20th century,” he said.
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While controlling these factors can be difficult, Kim said, modifications to diet and lifestyle could make a substantial impact — particularly when implemented in youth and early adulthood.
“Caring for our gut’s microbiome — the internal mechanism responsible for absorption of vitamins, regulation of the immune system, and assistance with food digestion – is essential,” he said.
To ensure a healthy microbiome, the doctor recommends avoiding ultra-processed foods, exercising to prevent obesity, and avoiding smoking and alcohol consumption.
It is also important for health care providers to make cancer screening options more accessible for younger people, Kim said.
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“All too often, primary care physicians may not recommend early screenings, because cancer has traditionally been associated with older ages and the screening guidelines have focused on age-based strategies,” he said.
“Expanding cancer research efforts focused on younger individuals is another critical area for improvement,” Kim added.
The ACS also calls for access to “affordable, comprehensive health insurance” for younger generations to increase screening rates.
The incidence of cancer among people under age 50 around the world is projected to increase by 31% by 2030, studies have shown.
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“There is an epidemic of young people being diagnosed with cancer occurring right in front of us, and unless we implement some urgent interventions, I fear we will continue to observe more young people with cancer over the next decade,” Kim said.
“We cannot wait that long.”
Fox News Digital reached out to the ACS researchers for additional comment.
Health
Is suicide contagious? Mental health experts warn of very real risk
This story discusses suicide. If you or someone you know is having thoughts of suicide, please contact the Suicide & Crisis Lifeline at 988 or 1-800-273-TALK (8255).
Suicide is a leading cause of death in the U.S., with more than 49,000 people taking their own lives in 2022, according to the Centers for Disease Control and Prevention (CDC).
Although most suicides stem from mental health disorders, statistics show that the behavior can sometimes be “contagious,” leading to “suicide clusters.”
Suicide clusters are defined as “a group of suicides or suicide attempts that occur closer together in time, space or both than would normally be expected in a community,” the CDC states.
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Dr. Caroline Fenkel, a licensed clinical social worker in Pennsylvania, who is an expert in suicide prevention, confirmed that the act can have a contagion effect — particularly among young people.
“When individuals hear about a suicide, especially someone close to their age or in their community, it can feel more accessible as an option in moments of distress,” she told Fox News Digital.
“The more the details are shared, especially in sensational ways, the greater the risk.”
Up to 5% of youth suicides can be attributed to contagion, according to Jennifer Kelman, a licensed clinical care social worker in Florida who works with JustAnswer, an expert help on-demand platform.
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“It doesn’t necessarily increase for everyone in that community, but rather for those who are struggling as well — with depression, anxiety and other feelings that may be overwhelming,” she told Fox News Digital.
5 possible reasons for suicide contagion
Dr. Deborah Gilman, owner and chief licensed psychologist at Fox Chapel Psychological Services in Pennsylvania, shared the following four factors that could contribute to suicide clusters.
1. Normalization
When people hear about suicides, it can normalize the idea of using it as a way to deal with problems, according to Gilman.
“People often look to others for cues on how to behave,” she told Fox News Digital.
“If they see that many others are choosing suicide, they may believe that it is the socially acceptable or ‘correct’ thing to do.”
2. Copying or modeling
“Some individuals may feel a sense of connection or empathy with the person who died and may imitate their actions,” Gilman said.
“In close-knit communities, schools or social groups, the suicide of one member can lead to others in the same environment feeling similar distress or engaging in similar behaviors.”
“The more the details are shared, especially in sensational ways, the greater the risk.”
Some individuals may imitate the behavior of someone who has died by suicide, especially if they are already struggling with their own mental health, she said.
“This can be due to a sense of hopelessness or a desire to escape their own pain.”
3. Social proof
People may believe that if others are choosing suicide, it must be a valid option for them as well, according to Gilman.
“From social learning theory, if the observed behavior — in this case, suicide — is seen as a positive outcome or a solution to problems, it may be reinforced and more likely to be imitated.”
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This risk can escalate when a celebrity or widely admired person dies by suicide, she added, as it can have a disproportionate impact on those who look up to that individual.
4. Vulnerability
“Individuals who are already struggling with mental health issues — especially depression and anxiety — may be more likely to experience suicidal thoughts or behaviors,” Gilman warned.
Those experiencing difficult life circumstances — such as job loss, divorce or financial struggles — may be more susceptible, she added.
5. Recency bias
“People tend to overestimate the likelihood of events that are easily recalled,” Gilman said.
“If a recent suicide has been widely publicized, it may make the idea of suicide more accessible and salient in people’s minds.”
6 warning signs among survivors
For those impacted by suicide, experts agreed that it’s important to watch for signs of deep distress, including the following.
1. Increased suicidal thoughts
“Experiencing recurring or intensifying thoughts of suicide is a critical warning sign that immediate professional help is necessary,” Gilman advised.
“For instance, the survivor may start having more frequent thoughts about ending their own life or making plans for it.”
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They may also express feelings of being overwhelmed to the point where they believe suicide is the only option, she said.
2. Feelings of being a burden
People saying they feel like a burden is a “major red flag,” according to Thomas Banta, a clinical mental health counselor in Jeffersonville, Indiana.
“Many people who try to end their lives feel they are doing the people around them a favor,” he told Fox News Digital.
“When we hear that type of language, intervention is essential.”
3. Inability to cope with daily life
“Difficulty managing daily responsibilities or activities can indicate that the emotional burden is too great to handle without professional support,” Gilman said.
The survivor may struggle to maintain a job, manage household duties or care for themselves due to their emotional state.
4. Risky behaviors
Engaging in unsafe or self-harming actions is a serious sign that mental health treatment is needed, experts agree.
“For example, the survivor may start harming themselves physically, such as cutting or burning, as a means of dealing with their emotional pain,” said Gilman.
“Many people who try to end their lives feel they are doing the people around them a favor.”
“Or they may engage in dangerous activities, like reckless driving, promiscuous sex or substance abuse, which puts their health and safety at risk.”
5. Severe mood or behavior changes
Significant changes in behavior or mood that affect a survivor’s ability to function in everyday life can be a sign that they need help, according to Gilman.
This might involve the survivor becoming unusually aggressive, withdrawn or apathetic, or displaying behavior that is significantly different from their “normal” demeanor.
6. Withdrawal from support systems
“Pulling away from friends, family or support groups can indicate that the survivor is struggling more than they can manage on their own,” Gilman warned.
The person might avoid social interactions, decline invitations or isolate themselves from people who usually offer support.
The signs aren’t always obvious, however, Banta noted.
“We also see the opposite end of the spectrum, where somebody will make a plan, and their mood lifts because they feel like they have found an escape,” he said.
Preventing contagion after a suicide
Experts offered the following tips to help reduce the risk of “clusters” following a suicide.
1. Use careful communication
“It’s important to be cautious about how we discuss suicide publicly,” Fenkel said.
“Reaching out for support is a sign of strength, not weakness.”
The best way to prevent contagion is through responsible communication, she advised.
“This includes limiting the specifics around the method of suicide and focusing on the impact of the loss,” she said.
2. Offer support
Offering access to crisis resources can help vulnerable individuals feel connected and supported, Fenkel said.
“It’s crucial to highlight help and hope, encouraging those who are struggling to seek support,” she said, noting that many schools and communities provide mental health services to help those who are grieving.
Banta agreed, noting that intervention and higher levels of care can stabilize people and help them develop a robust support system.
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“In terms of public health communication, we must let people know that treatment works and that there is effective help out there,” he said.
3. Stop the stigma
“Stigma can lead to feelings of isolation and loneliness, which can contribute to suicidal ideation,” Gilman warned.
When people feel comfortable discussing their mental health concerns without fear of judgment, they are more likely to seek help from professionals, she noted.
Fenkel agreed, encouraging people to talk openly and compassionately about mental health.
“Anyone experiencing thoughts of suicide should know that there is help available, and reaching out for support is a sign of strength, not weakness,” she said.
Suicide is a “fleeting state of mind,” Banta pointed out.
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“I have worked with many people who felt hopeless and that their lives would never improve, but then they did,” he said.
“So if you are struggling and reading this, there is help. Don’t give up.”
Health
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Health
Superbugs due to antibiotic resistance could kill 39 million people by 2050, large study finds
Resistance to antibiotics has led to one million worldwide deaths each year since 1990, for a total of 36 million.
It is expected to cause more than 39 million more fatalities by 2050 — three per minute.
That’s according to a large study led by the Global Research on Antimicrobial Resistance (GRAM) Project, a partnership between the University of Oxford and the Institute for Health Metrics and Evaluation (IHME) at the University of Washington.
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After analyzing 520 million health records, the researchers provided future estimates for 22 pathogens, 84 pathogen-drug combinations and 11 infectious syndromes across 204 countries and territories, according to a GRAM press release.
Findings from the study were published in The Lancet on Monday.
What is antimicrobial resistance?
Antimicrobial resistance (AMR) occurs when bacteria and other types of germs become stronger than the medications given to treat them, creating so-called “superbugs.”
This can make infections difficult or impossible to treat, per the U.S. Centers for Disease Control and Prevention (CDC).
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“In modern medicine, the use of antibiotics has allowed us to successfully perform organ transplants, complex surgical procedures and care for extremely preterm infants,” Jasmine Riviere Marcelin, MD, a fellow of the Infectious Diseases Society of America and infectious diseases professor at the University of Nebraska — who was not involved in the study — told Fox News Digital.
“These interventions have been successful because antibiotics have allowed us to prevent and treat infections in these critically ill patients.”
Now, antibiotic-resistant bacteria pose a “significant health risk,” she warned, because they prevent the ability to treat or prevent infections.
“Not only will our advancements in medicine be at risk, but we may find ourselves back to where we were in the pre-antibiotic era, when mortality from simple skin/soft tissue infections was significant,” Marcelin added.
“We may find ourselves back to where we were in the pre-antibiotic era.”
Maureen Tierney, MD, associate dean of clinical research and public health at Creighton University School of Medicine in Omaha, Nebraska, was also not involved in the study, but confirmed that it is “the most comprehensive attempt to determine the burden of antimicrobial resistance [in terms of] disability and death.”
“This was an enormous effort using all different sources of data in countries around the world to estimate the number of deaths caused by microorganisms resistant to several types of antibiotics,” she told Fox News Digital.
Marking key shifts
Since 1990, the infection that caused the biggest increase was MRSA (methicillin-resistant S. aureus), a type of staph bacteria that has become resistant to some antibiotics.
Annual MRSA-related deaths increased from 57,200 in 1990 to 130,000 in 2021, the study found.
Despite the overall increase in AMR-related mortality, deaths among kids younger than 5 were cut in half between 1990 and 2021.
The researchers attributed this to childhood vaccination programs and wider access to drinking water, sanitation and hygiene practices.
The sharpest increase was among adults 70 and older, who saw a more than 80% uptick in AMR deaths.
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“Researchers expect these trends to continue in the coming decades, with AMR deaths among children under 5 projected to halve by 2050 globally, as deaths among people 70 years and older more than double,” the press release stated.
Geographically, deaths rose the most in western sub-Saharan Africa, tropical Latin America, high-income North America, Southeast Asia and South Asia.
Combating antimicrobial resistance
Next week, global health leaders plan to meet at the UN General Assembly in New York to discuss new strategies for addressing AMR.
Potential interventions include “infection prevention and control measures, such as new vaccines and antimicrobials, and improved access to water and sanitation — as well as deeper investments across health systems in diagnostics, training and new technologies,” the release stated.
“The most important ways to decrease the incidence of antibiotic resistance are vaccination for pneumonia, influenza, COVID, measles and other diseases,” Tierney from Creighton University told Fox News Digital.
Tierney also calls for “antimicrobial stewardship” – which she defines as “the judicious use of antibiotics in humans, animals and farming” – as well as infection prevention practices, especially in health care facilities, and the development of new antibiotics.
“Antibiotics are a shared natural resource that we must all protect.”
While creating new drugs is one way to combat AMR, Marcelin warned that relying only on drug discovery would be “futile,” given the length of time it takes for new medications to be developed, tested and approved.
“The number of new or repurposed antibiotics in late-stage clinical development is very small, and no single antibiotic candidate claims to have activity against those bacteria resistant to all currently available drugs,” she told Fox News Digital.
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“If we can’t make new drugs easily, we can combat resistance by controlling the spread of resistant organisms, which is the principle of infection control.”
To prevent resistance, Marcelin agrees that antibiotics should be prescribed and used “only when they are indicated, for the optimal duration, and at the right timing and dosing regimen.”
She added, “Antibiotics are a shared natural resource that we must all protect, so that we can continue to live in a world where we make medical advances and reduce mortality from bacterial infections.”
For more Health articles, visit www.foxnews.com/health
Fox News Digital reached out to GRAM researchers requesting comment.
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