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Scientists crack code on how dietary fiber shields your body from harmful sugar damage

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Scientists crack code on how dietary fiber shields your body from harmful sugar damage

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A new UC Irvine study may have finally uncovered how dietary fiber protects the body from sugar’s damage, and how protecting yourself starts in the gut.

Researchers at the UCI School of Medicine found that inulin, a naturally occurring fiber found in vegetables like onions, garlic and artichokes, can reshape the bacteria living in your gut to stop fructose before it hits your liver.

“We found that consuming a type of dietary fiber called inulin… changes the bacteria in the gut to promote the consumption of harmful dietary fructose,” said lead researcher Cholsoon Jang, PhD, of UCI’s Nutrient Metabolism & Disease Lab. 

The findings, published in Nature Metabolism, reveal a new level of protection offered by fiber, not just in digestion, but in how the body handles sugar at the molecular level.

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Scientists say fiber could help prevent or reverse early signs of fatty liver disease. (iStock)

Jang and his team discovered that when people eat fructose (a common sugar in fruit and sweetened foods) gut bacteria in the small intestine can metabolize it before it reaches the liver. But without enough fiber, too much fructose “spills over,” overwhelming the liver and triggering fat buildup.

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Fructose is a sugar found in fruit that can ‘spill’ into the liver, leading to liver disease. (iStock)

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By feeding gut bacteria with inulin, researchers found that the microbes essentially burn through fructose early, preventing that cascade of damage. 

Even more striking, once these bacteria were “primed” by inulin, they were able to reverse signs of fatty liver disease, reducing fat accumulation and boosting the liver’s natural antioxidants.

EXPERTS REVEAL 5-STEP APPROACH TO A HEALTHIER GUT AND STRONGER IMMUNITY

Jang says the research proves not all calories are created equal.

He says their work gives “insight into how fiber protects our health from harmful nutrients like fructose.”

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The Nature Metabolism study identified how specific gut bacteria metabolize sugar before it reaches the liver. (iStock)

The study focused on non-obese participants: people who might otherwise slip under the radar yet still face hidden risks from high-sugar diets. 

Jang noted that metabolic damage isn’t limited to those who are overweight. Even people who appear healthy can experience liver stress and insulin resistance if their gut microbes aren’t equipped to handle excess fructose.

“By identifying specific gut bacteria and metabolic pathways involved, our findings can guide personalized nutrition strategies,” Jang said.

Vegetables like garlic, artichokes and onions can be a good source of inulin, the helpful fiber studied by the research team. (iStock)

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He added that future research will explore whether other common fibers beyond inulin can trigger similar protective effects.

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The implications stretch far beyond the lab. If certain fibers can train gut microbes to neutralize sugar before it harms the liver, it could open the door to new treatments for fatty liver disease, diabetes, obesity and even cancer.

For now, researchers explain that the findings indicate that fiber not only aids digestion but can be a defender of metabolic health.

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As Jang put it: “For example, by checking how well someone’s gut bacteria clears fructose before the body absorbs it, we can choose the right prebiotic or probiotic supplement for that person to improve results and reduce side effects.”

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Man’s extreme energy drink habit leads to concerning medical discovery, doctors say

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Man’s extreme energy drink habit leads to concerning medical discovery, doctors say

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Eight energy drinks per day may lead to serious health consequences, recent research suggests.

A relatively healthy man in his 50s suffered a stroke from the overconsumption of unnamed energy beverages, according to a scientific paper published in the journal BMJ Case Reports by doctors at Nottingham University Hospitals in the U.K.

The unnamed man was described as “normally fit and well,” but was experiencing left-side weakness, numbness and ataxia, also known as poor coordination or unsteady walking. 

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When the man sought medical attention, it was confirmed via MRI that he had suffered an ischemic thalamic stroke, the report stated.

The patient’s blood pressure was high upon admission to the hospital, was lowered during treatment and then rose again after discharge, even though he was taking five medications.

The 50-year-old man (not pictured) admitted to drinking eight energy drinks per day. (iStock)

The man revealed that he consumed eight cans of energy drink per day, each containing 160 mg of caffeine. His caffeine consumption had not been recorded upon admission to the hospital.

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Once the man stopped drinking caffeine, his blood pressure normalized, and he was taken off antihypertensive medications.

High caffeine content can raise blood pressure “substantially,” a doctor confirmed. (iStock)

Based on this case, the authors raised the potential risks associated with energy drinks, especially regarding stroke and cardiovascular disease.

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They also highlighted the importance of “targeted questioning in clinical practice and greater public awareness.”

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The authors say this case draws attention to the potential dangers of over-consuming energy drinks. (iStock)

Fox News senior medical analyst Dr. Marc Siegel reacted to the case study in an interview with Fox News Digital.

“This case report illustrates the high risk associated with a large volume of energy drink consumption, especially because of the high caffeine content, which can raise your blood pressure substantially,” said Siegel, who was not involved in the study.

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“In this case, the large amount of caffeine appears to have led directly to very high blood pressure and a thalamic stroke, which is likely a result of that soaring blood pressure.”

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Fox News Digital reached out to the case study authors and various energy drink brands for comment.

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5 Surprising Ozempic Side Effects Doctors Are Finally Revealing (Like Back Pain and Hair Loss)

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5 Surprising Ozempic Side Effects Doctors Are Finally Revealing (Like Back Pain and Hair Loss)


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Relationship coach blames Oprah for pushing family estrangement ‘for decades’

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Relationship coach blames Oprah for pushing family estrangement ‘for decades’

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Oprah Winfrey is shining a light on family estrangement, which she calls “one of the fastest-growing cultural shifts of our time” — but one expert says the media mogul helped fuel that very culture.

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“A Cornell University study now shows that almost one-third of Americans are actively estranged from a family member,” Winfrey said on a recent episode of “The Oprah Podcast,” referring to adult children going “no-contact” with parents, siblings or entire family systems.

Winfrey said the trend is a “silent epidemic” that can be especially relevant during the holidays.

ONE TOXIC BEHAVIOR KILLS RELATIONSHIPS, LEADING HAPPINESS EXPERT WARNS

But family and relationship coach Tania Khazaal, who focuses on fighting “cutoff culture,” took to social media to criticize Winfrey for acting as if the estrangement crisis appeared “out of thin air.”

“Now Oprah is shocked by the aftermath of estrangement, after being one of the biggest voices pushing it for decades,” Canada-based Khazaal said in an Instagram video, which drew more than 27,000 likes and 3,000 comments.

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Oprah Winfrey recently discussed what she called a “silent epidemic” of family estrangement on her podcast. (Theo Wargo/Getty Images)

Khazaal claimed that Winfrey’s messaging started in the 1990s and has contributed to a cultural shift where walking away became the first resort, not the last.

According to the relationship coach, millennials, some of whom grew up watching Oprah, are the leading demographic cutting off family members — and even if it wasn’t intentional, “the effect has absolutely been harmful,” Khazaal told Fox News Digital.

FAMILY BREAKUPS OVER POLITICS MAY HURT MORE THAN YOU THINK, EXPERT SAYS

The coach, who has her own history with estrangement, questioned why Winfrey is now treating the issue as a surprising crisis.

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“Now she hosts a discussion with estranged parents and estranged kids, speaking on estrangement like it’s some hidden, sudden, heartbreaking epidemic that she had no hand in,” she said in her video.

Nearly one-third of Americans are estranged from a family member, research shows. (iStock)

Khazaal said she believes discussions about estrangement are necessary, but insists that people shouldn’t “rewrite history.”

“Estrangement isn’t entertainment or a trending conversation piece,” she added. “It’s real families, real grief, parents dying without hearing their child’s voice.”

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Winfrey reportedly responded in the comments, writing, “Happy to have a conversation about it — but not on a reel. Will have my producer contact you if you’re interested.” But the comment was later deleted due to the backlash it received, Khazaal told Fox News Digital.

“I would still be open to that discussion,” Khazaal said. “The first thing I’d want her to understand is simple: Setting aside cases of abuse or danger, the family unit is the most sacred structure we have.” 

Experts emphasize that estrangement should be a last resort. (iStock)

“When children lose their sense of belonging at home, they search for it in the outside world,” she added. “That’s contributing to the emotional fragility we’re seeing today.”

Her critique ignited a debate online, with some social media users saying Khazaal is voicing a long-overdue concern.

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“The first time I heard, ‘You can love them from a distance’ was from Oprah … in the ’90s,” one woman said.

My son estranged himself from us for five years,” one mother commented. “The pain, hurt and damage never goes away.”

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Others, however, argued that Winfrey’s podcast episode was empathetic and that estrangement shouldn’t be oversimplified.

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Mental health experts say the conversation around estrangement is more complex than any single celebrity influence, and reflects broader cultural shifts.

Experts say today’s focus on boundaries and emotional well-being has reshaped family expectations. (iStock)

In the episode with Winfrey, Joshua Coleman, a California-based psychologist, said, “The old days of ‘honor thy mother and thy father,’ ‘respect thy elders’ and ‘family is forever’ has given way to much more of an emphasis on personal happiness, personal growth, my identity, my political beliefs, my mental health.” 

Coleman noted that therapists sometimes become “detachment brokers” by unintentionally green-lighting estrangement.

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Jillian Amodio, a licensed master’s social worker at the Maryland-based Waypoint Wellness Center, told Fox News Digital that while public figures like Winfrey help normalize these conversations, estrangement might just be a more openly discussed topic now.

“Estrangement used to be handled privately and quietly,” she said.

Winfrey’s take on family estrangement is prompting a broader discussion amid the holiday season. (iStock)

But even strained relationships can be fixed with the right support, experts say.

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Susan Foosness, a North Carolina-based clinical director of patient programs at Rula Health, said families can strengthen their relationships by working with a mental health professional to improve communication, learn healthier conflict-resolution skills, and build trust and empathy through quality time together.

“No family is perfect,” Foosness told Fox News Digital.

Khazaal agreed, saying, “Parents need to learn how to listen without slipping into justification, and children need help speaking about their pain without defaulting to blame or avoidance.”

Fox News Digital reached out to Winfrey for comment.

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