Health
Psychedelic drug popular in 1960s could ease anxiety as doctors share warnings
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A new study suggests that lysergic acid diethylamide (LSD), also known as acid, could reduce anxiety.
This marks the first-ever trial to evaluate the safety and efficacy of MM120 (a pharmaceutical formulation of LSD) as a monotherapy for patients with moderate to severe generalized anxiety disorder, according to lead author Daniel Karlin, M.D., chief medical officer of MindMed, a biopharmaceutical company in New York.
The study was published in the Journal of the American Medical Association.
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Nearly 200 adults between the ages of 18 and 74 received either a single oral dose of LSD at various does, or a placebo “dummy pill,” for a three-month period, according to a press release.
The dosing sessions were individually conducted in private rooms with two trained monitors who observed the participants for at least 12 hours. No psychotherapy was provided.
A new study suggests that lysergic acid diethylamide (LSD), also known as acid, could reduce anxiety. (iStock)
Researchers tracked changes in participants’ anxiety scores at weeks 1, 2, 4, 8 and 12, with week 4 serving as the main point of evaluation.
After the four weeks, patients receiving the highest doses had significantly lower anxiety scores than the others.
At 12 weeks, 65% of patients taking 100 milligrams showed benefits, with nearly 50% in remission from anxiety.
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Researchers also tested LSD’s impact on depression, finding that the highest doses were linked to significant improvements.
Karlin shared that the effects of LSD were almost immediate. Side effects of the psychedelic included hallucinations, nausea and headaches.
LSD was shown to reduce symptoms in adults with generalized anxiety disorder, with 100-microgram doses proving most effective in a clinical trial. (iStock)
The effects were dose-dependent, with 100 milligrams being the optimal dose. The 200-milligram dose also significantly outperformed the placebo. The 25-milligram and 50-milligram doses did not show significant benefits.
One possible study complication was “functional unbinding,” in which trial participants could correctly guess whether they had received the active medication versus a placebo, according to Karlin.
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The drugmaker plans to conduct two large, late-stage trials to track patients over a longer period of time.
If the study is deemed successful, MindMed will submit the drug to the U.S. Food and Drug Administration for approval.
Risks and legalities
LSD is classified as a Schedule I drug, which means it’s considered to have high potential for abuse and no accepted medical use, according to the Drug Enforcement Agency.
Schedule I drugs are not legally allowed to be prescribed, dispensed or used in medical treatment, except for approved research.
If the study is deemed successful, Mindmed will submit the experimental drug to the FDA for approval. (iStock)
The FDA has designated LSD, psilocybin and MDMA as “potential breakthrough therapies,” Fox News senior medical analyst Dr. Marc Siegel told Fox News Digital.
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“The key is careful oversight and meticulous research, which monitors both side effects and effectiveness,” said Siegel.
While this new study shows a “very positive result in around 200 patients,” Siegel confirmed that LSD can cause hallucinations.
Additional documented side effects may include paranoia, mood swings, increased heart rate and long-term psychosis, according to multiple sources.
“The key is careful oversight and meticulous research, which monitors both side effects and effectiveness.”
Hadas Alterman, a psychedelic medicine attorney in Washington, D.C., told Fox News Digital that “LSD’s return is not just cultural or scientific, it’s regulatory.”
The expert says psychedelics were “sidelined” due to the “sweeping expansion of FDA authority under the 1962 Kefauver–Harris Amendments.”
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This legislation, also called the Drug Efficacy Amendments, required drug manufacturers to provide substantial evidence of efficacy through well-controlled clinical trials before approval.
“LSD and other psychedelics have long shown clinical promise, but the excess recreational use in the 1960s pushed researchers away from continuing to study it,” Siegel added.
“LSD and other psychedelics have long shown clinical promise, but the excess recreational use in the 1960s pushed researchers away from continuing to study it,” a doctor said. (iStock)
Health and Human Services Secretary Robert F. Kennedy Jr. and Department of Veterans Affairs Secretary Doug Collins have conveyed interest in exploring psychedelic therapy.
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“This line of therapeutics has tremendous advantage if given in a clinical setting, and we are working very hard to make sure that happens within 12 months,” RFK recently told members of Congress, per AP.
Psychedelics advocate Alterman noted that while the support “doesn’t replace science,” it encourages institutions like FDA to “take this seriously.”
Health
Faith drives man to help another through mental health crisis in dramatic life-or-death scene
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This story discusses suicide. If you or someone you know is having thoughts of suicide, please contact the Suicide & Crisis Lifeline at 988 or 1-800-273-TALK (8255).
The arc of a man’s life changed dramatically after a Jacksonville police officer, along with a team of other officers, stepped in to help an individual in crisis on the Dames Point Bridge in Florida in April.
Faith had everything to do with it.
Body camera footage taken on April 12 shows Officer Antonio Richardson speaking with a man who was standing on the edge of the bridge — getting ready to jump. Richardson, along with six other patrol officers, responded to the emergency.
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“Whatever you’re going through, man, you can get through it,” Richardson can be heard saying to the man during the drama.
“Now listen, man. Listen. Listen. You can get through this,” he told the individual as police lights flashed behind them.
The arc of a man’s life changed dramatically after a Jacksonville police officer, along with a team of other officers, stepped in to help an individual in crisis on the Dames Point Bridge in Florida. (iStock)
“Let’s talk about it for a minute. … You believe in prayer, I know that. … Just touch my hand. Just touch my hand, man, I’m praying with you,” said Richardson to the man.
The officer, for about 40 minutes, kept up a steady stream of conversation and outreach to the man, who was teetering on the edge of the bridge, looking at the water below him.
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Richardson told the man, as he kept his arm outstretched, “If you jump, you’re going to hurt other people. And they’re going to be hurting just like you’re hurting now. … The cycle’s gotta stop.”
“I just felt within myself that God was going to spare his life.”
Finally, after many moments, the man stepped away from the bridge and walked toward the officer — and they hugged. Other officers then stepped in as well.
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Appearing on “Fox & Friends” to discuss the incident this week, Richardson said, “When I got the call … I was just there to stop the traffic. And then a couple of other officers who knew my position as a pastor asked me to come over and talk with the guy. … Nothing was scripted. … I did not want to see him jump,” he added.
The officer, who is also a pastor (not pictured), said, “I was praying. And God spared his life. And we connected. And as a result of that connection, he didn’t jump.” (iStock)
“I just felt within myself that God was going to spare his life — and he did.”
He also said, “I was praying. And God spared his life. And we connected. And as a result of that connection, he didn’t jump.”
“This powerful story reminds us that we can all love our neighbors and be part of the solution in our nation.”
Officer Richardson has more than 30 years of ministry experience, according to reports. He said that after the man was safe and the immediate drama had passed, the officer called his wife, sat in his patrol car — “and wept like a baby.”
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Pastor Jesse Bradley of the Seattle area, who runs Grace Community Church and is the founder of the ministry Just Choose Hope, watched the video of the dramatic incident.
He told Fox News Digital, “This powerful story reminds us that we can all love our neighbors and be part of the solution in our nation. Every person is made in God’s image, loved by Jesus — and life is a gift.”
Jacksonville Police Officer Antonio Richardson, at right, shared the emotional story on “Fox & Friends” of how he talked a man off the edge of a bridge in Jacksonville, Florida, on April 12. (Fox News)
He added, “We are made to receive and give hope daily, where we live, work, learn and play.”
Bradley also said that people should “be intentional about pursuing others who are in need. Take relationship risks. In the parable of the Good Samaritan, there were two religious people who played it safe and remained in their comfort zone. We have a greater calling,” he said.
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“Only the Samaritan was willing to go to the man in pain and bring restoration. Let’s be people who cross the road to provide. Let’s be faithful to God. Love is intentional, takes action — and makes sacrifices. Let’s love and live like Jesus.”
“Instead of being separated from God, we can have peace with God and a full pardon through Jesus,” said a pastor, reflecting on the rescue that recently occurred in Jacksonville, Florida, during a man’s mental health crisis. (iStock)
Bradley observed that the inspiring story out of Florida “points us to the greatest rescue story of all. Jesus left heaven to pursue us.”
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He said, “We have all sinned against God and need a Savior. Jesus died on the cross, offering forgiveness, and rose from the grave to give us eternal life.
“Instead of being separated from God,” he added, “we can have peace with God and a full pardon through Jesus. This is grace, an undeserved gift. We will be with Jesus forever — an everlasting rescue.”
Health
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Health
How eating habits could influence Parkinson’s disease risk, according to experts
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Growing observational research suggests that long-term dietary patterns may influence Parkinson’s risk, age at onset and possibly severity of symptoms.
Mediterranean-style eating, in particular, has been associated with lower risk and possibly milder disease.
That said, there isn’t a single food that causes or prevents disease, according to Dr. Michael S. Valdez, a California-based physician with advanced training in neurology.
Growing observational research suggests that long-term dietary patterns may influence Parkinson’s risk, age at onset and possibly severity of symptoms. (iStock)
“When we talk about Parkinson’s and similar conditions, it helps to zoom out,” he told Fox News Digital. “In many cases, it’s the overall pattern over years that matters.”
The brain is especially sensitive to chronic inflammation, oxidative stress and vascular health, which is how well blood flows to brain tissue, according to the doctor.
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“Another key point is that neurodegenerative diseases develop slowly,” Valdez pointed out. “Changes in movement or cognition often appear years after underlying changes in the brain have already started.”
“That means lifestyle factors, including diet, are part of a much larger timeline that also includes genetics, environmental exposures, sleep and physical activity.”
Foods that could delay disease
No. 1: Mediterranean and MIND diets
Dr. Rebecca Gilbert, a seasoned neurologist and the chief mission officer at the American Parkinson Disease Association in New York, confirmed that the best foods for brain health are those that make up the MIND or Mediterranean diets.
“These diets emphasize whole grains, vegetables (especially green leafy vegetables), nuts, legumes and berries,” Gilbert told Fox News Digital. “Fish is the preferred animal protein, and olive oil is the preferred fat.”
Mediterranean-style eating, in particular, has been associated with lower risk and possibly milder disease. (iStock)
Studies have suggested that among those diagnosed with Parkinson’s disease, adherence to the MIND or Mediterranean diets prior to diagnosis was associated with later onset of the disease, according to the doctor.
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“These diets are good for the brain because they are rich in antioxidants and other anti-inflammatory nutrients that keep neurons healthy,” she said. “The diets also support clean blood vessels to the brain, which provide adequate blood flow containing the nutrients and oxygen that neurons need.”
No. 2: Flavonoid-rich foods
“Blueberries, strawberries, apples, tea and red wine in moderation have been associated with lower PD risk in large cohorts,” Amanda Hare, an expert nurse practitioner in the field of neurology and movement disorders, who is also a medical liaison at Rune Labs, told Fox News Digital.
The South Carolina-based expert cited a Harvard study that found men with the highest flavonoid intake had about 40% lower disease risk.
“A responsible expert would place diet in that broader context rather than overselling any single food.”
“Anthocyanins — the pigments in red/purple berries — are the subclass with the most consistent signal,” she said. “These compounds have antioxidant and anti-inflammatory effects and may cross the blood-brain barrier.”
No. 3: Coffee and caffeinated tea
Large studies have shown that regular coffee consumption is associated with lower Parkinson’s risk, according to Hare, although a direct cause can’t be proven.
Caffeine has been found to protect brain cells in animal studies by blocking a specific brain receptor called the adenosine A2A receptor, she said.
“The effect is stronger in men; hormone therapy appears to modify it in women,” Hare added.
Scientists have found early signs of the disease — clumps of a protein called alpha-synuclein — in the nerves of the digestive system. (iStock)
No. 4: Fatty fish and omega-3 sources
“Evidence is more suggestive than definitive, but diets higher in omega-3s – salmon, sardines, mackerel, walnuts and flaxseed – correlate with lower risk and may support general neuronal health,” Hare said.
YOUR DAILY COFFEE HABIT MAY PLAY A ROLE IN DEMENTIA RISK, STUDY FINDS
No. 5: Fiber and fermented foods
In some cases, Parkinson’s pathology may begin in the gut, and gastrointestinal symptoms, such as constipation, can precede diagnosis, experts agree.
Scientists have found early signs of the disease — clumps of a protein called alpha-synuclein — in the nerves of the digestive system.
Large studies have shown that regular coffee consumption is associated with lower Parkinson’s risk, according to Hare, although a direct cause can’t be proven. (iStock)
“Constipation is one of the strongest prodromal symptoms, often predating diagnosis by a decade or more,” Hare told Fox News Digital.
“Diets supporting a diverse gut microbiome – high fiber, fermented foods like yogurt, kefir, sauerkraut and kimchi – are an active research area, though we don’t yet have randomized trial evidence that changing your microbiome changes Parkinson’s risk.”
Foods associated with higher risk
No. 1: Dairy (particularly milk)
“This is a consistent but still-debated finding,” Hare said. “Multiple large cohorts have found that higher milk consumption is associated with modestly elevated PD risk, particularly in men.”
The signal is specific to milk, she noted, as cheese and yogurt don’t show the same consistent association.
Recent research, including the Nurses’ Health Study in 2025, has linked high ultraprocessed food intake to higher odds of early Parkinson’s symptoms. (iStock)
No. 2: Ultraprocessed foods
Recent research, including the Nurses’ Health Study in 2025, has linked high ultraprocessed food intake to higher odds of early Parkinson’s symptoms. This supports broader evidence of processed foods’ association with systemic inflammation, Hare noted.
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No. 3: Pesticide exposure via diet
Exposure to paraquat and rotenone, which are toxic chemicals often used as pesticides, are among the strongest environmental risk factors for Parkinson’s, according to Hare.
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“Eating organic produce when possible … is a reasonable precaution, though the bulk of pesticide risk in the Parkinson’s literature relates to occupational exposure, not dietary,” she noted.
No. 4: Excess saturated fat and red/processed meat
“Associations exist, but are less robust than the dairy or ultraprocessed findings,” Hare said.
There are some limitations and caveats for all of these dietary risk associations, she noted.
“Associations exist, but are less robust than the dairy or ultraprocessed findings,” the expert said about red meat consumption. (iStock)
“Epidemiology does not equal causation,” she emphasized. “Nearly all of the above comes from observational studies.”
Lifestyle behaviors can also come into play – people who eat Mediterranean diets, for example, also exercise more, smoke less and have more resources.
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“Diet is one lever among several,” Hare noted. “Exercise has stronger evidence than any food for both preventing Parkinson’s and slowing progression. Sleep quality, cognitive engagement and avoidance of head injury also matter.”
“A responsible expert would place a diet in that broader context rather than overselling any single food.”
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