Health
PETA pleads with NIH to stop funding for animal study, calls sleep experiment 'cruel and horrific'
People for the Ethical Treatment of Animals (PETA) has reached out not only to the National Institutes of Health (NIH) with a plea, but to Florida Gov. Ron DeSantis as well, asking him to help stop a planned research study at the University of Wisconsin-Madison, which it claims involves cruelty to animals.
The study, intended to gather information about age-related cognitive decline, involves disrupting the sleep of aged marmosets, which are small, long-tailed South American monkeys.
“As the governor of the state with the largest number of older Americans, [DeSantis] is in a unique position to condemn — before they begin — planned ‘aging’ experiments on tiny marmoset monkeys,” PETA articulated in an email to Fox News Digital about its outreach.
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“PETA has obtained documents showing that [a research team] is going to be waking the monkeys every 15 minutes all night long by blaring loud noise at them,” the email continued.
In the letter to DeSantis, which was shown exclusively to Fox News Digital, Kathy Guillermo, senior vice president of PETA’s Laboratory Investigations Department, described the study as “horrific.”
People for the Ethical Treatment of Animals (PETA) reached out to the National Institutes of Health about a planned study to take place at the University of Wisconsin-Madison (shown above, left). The study will disrupt the sleep of aged marmosets in an attempt to learn more about age-related cognitive decline. PETA sent a letter to Gov. Ron DeSantis of Florida as well, hoping that he might step in as the governor of a state with “the largest number of older Americans.” (iStock)
“Keeping a monkey from sleeping — considered a form of torture in humans that can ultimately result in death — won’t mimic insomnia in people,” she wrote.
“This proposed experiment is so cruel that it’s classified by the university as what’s called a ‘Column E’ study — meaning it causes distress and pain without any relief.”
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The study, funded by the National Institutes of Health (NIH), is led by Agnès Lacreuse, a professor at the University of Massachusetts–Amherst, and will be conducted at the Wisconsin National Primate Research Center at the University of Wisconsin-Madison, according to records on the NIH website.
PETA sent this letter to Florida Gov. Ron DeSantis asking for his help in stopping a planned study to take place at the University of Wisconsin-Madison. It says the Sunshine State has over 412,000 PETA members and supporters in Florida. (PETA)
PETA sent a second, more detailed letter to the NIH.
“The proposed experiments involve causing nonhuman primates irreversible harm for experiments that offer little to no new scientifically valuable knowledge or human benefit,” stated the letter, which is signed by Katherine V. Roe, Ph.D., a neuroscientist at PETA’s Laboratory Investigations Department.
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Roe urged the NIH to “consider discontinuing funding for these extremely invasive experiments so that those resources can be directed toward research that could actually help our ever-growing aging population.”
The study, intended to gather information about age-related cognitive decline, involves disrupting the sleep of aged marmosets, which are small, long-tailed South American monkeys. (iStock)
In a statement to Fox News Digital, Roe of PETA acknowledged that “improving the lives of the aging population in the U.S. is of ever-increasing importance and deserves serious attention from the scientific community.”
She also stated, however, “It is appalling that the NIH is wasting taxpayer funds waking marmosets up night after night in experiments that are not only cruel and unnecessary, but have no chance of improving human health.”
Roe suggested that “better studies can and have been done with human volunteers.”
The People for the Ethical Treatment of Animals (PETA) corporate headquarters building in Norfolk, Virginia, in May 2023. (iStock)
“The NIH and the Wisconsin National Primate Center should be ashamed of themselves for subjecting these monkeys to maximum pain experiments under the guise of meaningful science,” she added.
University defends the study’s safety, importance
Michelle Ciucci, faculty director of the University of Wisconsin-Madison Animal Program and professor of surgery, told Fox News Digital that researchers at the University of Wisconsin-Madison and University of Massachusetts-Amherst are collaborating on a study of Alzheimer’s disease.
“They are focusing on the role [that] poor sleep plays in this debilitating disorder that often results in deadly complications,” she said.
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Their goal, she said, is to develop a new way to study Alzheimer’s.
“To better understand and combat human diseases like Alzheimer’s, researchers must turn to animals to mimic complex human biology,” Ciucci said.
“Nonhuman primates like marmosets share similar features of their biology with humans — in particular, their brains — and offer opportunities to study the causes of Alzheimer’s and potential treatments,” a faculty director and researcher told Fox News Digital. (iStock)
“Nonhuman primates like marmosets share similar features of their biology with humans — in particular, their brains — and offer opportunities to study the causes of Alzheimer’s and potential treatments.”
In this NIH-funded pilot study, researchers plan to disrupt the sleep of adult marmosets, a primate species that is often used in brain studies, noted Ciucci.
“To better understand and combat human diseases like Alzheimer’s, researchers must turn to animals to mimic complex human biology.”
“Other scientists have discovered connections between disrupted sleep and conditions including dementia and Alzheimer’s, but have not yet established poor sleep as a cause of those disorders,” she said.
During the course of the study, a small group of the animals will be awakened from sleep several times over the course of one night, Ciucci said.
The study will be conducted at the Wisconsin National Primate Research Center at the University of Wisconsin-Madison, according to NIH records. (iStock)
In later phases, they will be awakened over the course of three nights in a row.
“The animals, attended to by specially trained veterinarians in carefully managed conditions, will be awakened by sound — short tones played at about the same volume as a normal conversation or an alarm clock,” she said. “The sound will be loud enough to wake the animals but not scare them.”
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The researchers will track the animals’ behavior, cognitive skills and other “biological indicators” to determine whether the sleep disruptions result in cognitive impairment and biochemical changes similar to those seen in human Alzheimer’s patients, the researcher told Fox News Digital.
As far as why the study is classified as “Category E,” Ciucci said it’s possible that the sleep disruptions “may cause discomfort that cannot be addressed with typical methods like medication.”
It would be “unethical and difficult” to use humans in a study to explore sleep’s role in the development of a disease like Alzheimer’s, researchers noted. (iStock)
“Providing medications or other means of relief would interfere with the validity of the study and its interpretations,” she said.
It would be “unethical and difficult” to use humans in a study to explore sleep’s role in the development of a disease like Alzheimer’s, the researcher noted.
“Until scientists understand the causes and development of Alzheimer’s in a way that helps them study more treatments in humans, studying animal models of the disease remains necessary to researchers, patient advocacy organizations like the Alzheimer’s Association, the public and experts at federal agencies — including the National Institutes of Health, which vetted and funded the marmoset sleep study because they consider it promising and important to public health,” she added.
Fox News Digital reached out to both Gov. DeSantis’ office and to the NIH requesting additional comment.
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Collagen supplements have exploded in popularity, touted as everything from an anti-aging miracle to a muscle recovery booster.
But a sweeping new review conducted by U.K. researchers suggests that while collagen may help improve skin elasticity and ease arthritis pain, it does little for athletic performance or wrinkle reduction.
Researchers from Anglia Ruskin University analyzed 16 systematic reviews and 113 randomized controlled trials involving nearly 8,000 participants worldwide, which they say is the most extensive evaluation of collagen’s health effects to date.
The review found consistent evidence that collagen supplementation improves skin elasticity and hydration over time and provides significant relief from osteoarthritis-related joint pain and stiffness, according to findings published in Aesthetic Surgery Journal Open Forum.
A large U.K. review found that collagen supplements may improve skin elasticity and hydration over time. (iStock)
The researchers, however, did not find meaningful improvements in post-exercise muscle recovery, soreness or tendon mechanical properties (strength, springiness and stretch resistance).
“Collagen is not a cure-all, but it does have credible benefits when used consistently over time, particularly for skin and osteoarthritis,” co-author Lee Smith, professor of public health at Anglia Ruskin University, said in a statement.
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“Our findings show clear benefits in key areas of healthy aging, while also dispelling some of the myths surrounding its use,” Smith added.
Collagen, the most abundant protein in the body, supports skin, bones, tendons, cartilage and connective tissue, according to experts. Natural collagen production begins to drop in early adulthood and declines more sharply with age.
The study found that collagen supplements may help reduce joint pain and stiffness in people with osteoarthritis. (iStock)
The review found that long-term collagen supplementation was linked to improved skin firmness and hydration, but did not help skin roughness — a proxy for visible wrinkles.
Benefits appear to accumulate gradually, suggesting that collagen should not be viewed as an “anti-wrinkle ‘quick fix,’ but as a foundational dermal support for individuals seeking holistic skin maintenance,” the researchers said.
“If we define anti-aging as a product or technique designed to prevent the appearance of getting older, then I believe our findings do support this claim for some parameters,” Smith told the BBC. “For example, an improvement in skin tone and moisture is associated with a more youthful-looking appearance.”
Collagen supplementation was linked to reduced pain and stiffness in people with osteoarthritis, with stronger benefits seen over longer periods of use, and showed modest improvements in muscle mass and tendon structure that may support healthy aging.
Collagen did not significantly improve skin roughness, a marker of visible wrinkles. (iStock)
However, it did not show meaningful results when used as a fast-acting sports performance supplement, and evidence for benefits related to cholesterol, blood sugar, blood pressure and oral health was mixed or inconclusive.
Dr. Daniel Ghiyam, a California-based physician and longevity specialist, said the findings align with what he sees in clinical practice.
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“Collagen is a targeted support tool, not a foundation of health or performance,” Ghiyam, who was not involved in the study, told Fox News Digital. “When marketed that way, it makes sense. When marketed as a cure-all, it doesn’t hold up to the data.”
The authors noted that while many previous collagen studies have received financial support from the supplement industry, the current review did not receive industry funding.
Experts say collagen supplements may offer modest benefits for skin hydration and joint comfort, but they are not a cure-all. (iStock)
The team called for more high-quality clinical trials examining long-term outcomes, optimal dosages and differences between collagen sources, such as marine, bovine and plant-based alternatives.
Among its limitations, the review could not determine whether certain forms of collagen work better than others or what the optimal regimen should be.
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While the review included randomized controlled trials, the quality of the studies varied, with newer research generally showing stronger results.
Experts say more data and studies are needed to build on the findings. They also noted that diet plays a crucial role in skin health.
Collagen supplements, often sold as powders or pills, may improve skin elasticity and ease joint pain, experts say. (iStock)
Dr. Erum Ilyas, a Pennsylvania-based dermatologist and chair of dermatology at Drexel University College of Medicine, noted that the review analyzed previously published meta-analyses rather than generating new primary data.
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“At this time, I have not seen sufficiently strong independent evidence to routinely recommend collagen supplements to my patients,” Ilyas, who was not involved in the review, told Fox News Digital.
“Although some studies show modest improvements in markers such as hydration and elasticity, there remains limited independent, biopsy-confirmed evidence demonstrating sustained increases in dermal collagen content,” she added.
Fox News Digital has reached out to the researchers for comment.
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As colorectal cancer (CRC) is now the leading cause of cancer death in adults under 50, a new report reveals some surprising shifts in the incidence of the disease.
Although rates of CRC have been declining among seniors, those 65 and under are facing a rise in diagnoses, according to a report titled Colorectal Cancer Statistics, 2026, from the American Cancer Society.
Adults 65 and younger comprise nearly half (45%) of all new colorectal cancer cases — a significant increase from 27% in 1995, states the report, which was published in CA: A Cancer Journal for Clinicians.
The disease is rising fastest among adults 20 to 49 years old, at a rate of 3% per year.
Colorectal cancer is now the leading cause of cancer death in adults under 50. (iStock)
Among adults 50 and under, 75% of colorectal cancers are diagnosed at an advanced stage. Half of the diagnoses in that age range are made between the ages of 45 and 49. Although that age group is eligible to receive routine screenings, just 37% do so.
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The report also revealed that rectal cancer is on the rise, now accounting for about one-third (32%) of all CRC cases — an increase from 27% in the mid-2000s.
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“After decades of progress, the risk of dying from colorectal cancer is climbing in younger generations of men and women, confirming a real uptick in disease because of something we’re doing or some other exposure,” said Rebecca Siegel, senior scientific director, surveillance research at the American Cancer Society and lead author of the report, in a press release.
Among adults 50 and under, 75% of colorectal cancers are diagnosed at an advanced stage. Half of the diagnoses in that age range are made between the ages of 45 and 49. (iStock)
“We need to redouble research efforts to understand the cause, but also circumvent deaths through earlier detection by educating clinicians and the general public about symptoms and increasing screening in people 45-54 years.”
It is projected that 158,850 new cases of colorectal cancer will be diagnosed this year, and that the disease will cause 55,230 deaths, per the report.
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More than half of CRC cases can be linked to high-risk behaviors, the researchers said. Those include lack of nutrition, high alcohol consumption, smoking, lack of exercise and obesity.
“These findings further underscore that colorectal cancer is worsening among younger generations and highlight the immediate need for eligible adults to begin screening at the recommended age of 45,” said Dr. William Dahut, chief scientific officer at the American Cancer Society.
When the disease is caught at a local (early) stage, the five-year survival rate is 95%. (iStock)
“The report also shines a light on the crucial importance of continued funding for research to help discover new therapies to treat the disease and advance patient care.”
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When the disease is caught at a local (early) stage, the five-year survival rate is 95%, the report stated.
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A new study suggests that middle-aged men may be more vulnerable to faster biological aging, potentially linked to exposure to “forever chemicals.”
The research, published in the journal Frontiers in Aging, examined how perfluoroalkyl and polyfluoroalkyl substances, more commonly known as PFAS, could impact aging at the cellular level.
PFAS are synthetic chemicals commonly used in nonstick cookware, food packaging, water-resistant fabrics and other consumer products, the study noted.
Their chemical structure makes them highly resistant to breaking down, allowing them to accumulate in water, soil and the human body.
Chinese researchers analyzed blood samples from 326 adults enrolled in the U.S. National Health and Nutrition Examination Survey between 1999 and 2000.
A new study suggests that middle-aged men could face accelerated biological aging at the cellular level due to exposure to PFAS. (iStock)
The researchers measured levels of 11 PFAS compounds in participants’ blood and used DNA-based “epigenetic clocks” — tools that analyze chemical changes to DNA to estimate biological age — to determine how quickly their bodies were aging at the cellular level, the study stated.
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Two compounds, perfluorononanoic acid (PFNA) and perfluorooctanesulfonamide (PFOSA), were detected in 95% of participants.
Higher concentrations of those chemicals were associated with faster biological aging in men of certain age groups, but not in women.
“People should not panic.”
The compounds most strongly linked to accelerated aging were not the PFAS chemicals that typically receive the most public attention, the researchers noted.
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“The associations were strongest in adults aged 50 to 64, particularly in men,” Dr. Xiangwei Li, professor at Shanghai Jiao Tong University School of Medicine and the study’s corresponding author, told Fox News Digital.
“While this does not establish that PFAS cause aging, it suggests that these widely present ‘forever chemicals’ may be linked to molecular changes related to long-term health and aging.”
The study found that two of the compounds were detected in 95% of participants, and higher levels were linked to faster biological aging in men ages 50–64. (iStock)
Midlife may represent a more sensitive biological period, when the body becomes more vulnerable to age-related stressors, according to the researchers.
Lifestyle factors, such as smoking, may influence biological aging markers, potentially increasing vulnerability to environmental pollutants.
While Li said “people should not panic,” she does recommend looking for reasonable ways to reduce exposure.
That might mean checking local drinking water reports, using certified water filters designed to reduce PFAS, and limiting the use of stain- or grease-resistant products when alternatives are available.
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Meaningful reductions in PFAS exposure will likely depend on broader regulatory action and environmental cleanup efforts, Li added.
The researchers noted that midlife could be a particularly sensitive stage, when the body is more susceptible to stressors associated with aging. (iStock)
Study limitations
The researchers outlined several important limitations of the research, including that the findings show an association, but do not prove that PFAS directly causes accelerated aging.
“The study is cross-sectional, meaning exposure and aging markers were measured at the same time, so we cannot determine causality,” Li told Fox News Digital.
The study was also relatively small, limited to 326 adults age 50 or older, which means the findings may not apply to younger people or broader populations.
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Researchers measured PFAS levels using data collected between 1999 and 2000, and today’s exposure patterns may differ.
Li added that while PFAS is known to persist in the environment and the body, these results should be validated through larger, more recent studies that follow participants over time.
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