Health
Parvovirus or ‘slapped cheek disease’ is on the rise, CDC warns: Here’s what to know
A respiratory disease known as parvovirus B19 is on the rise in the U.S. among all age groups, according to a recent advisory from the U.S. Centers for Disease Control and Prevention (CDC).
The CDC issued the health alert on Aug. 13 after European public health authorities reported “unusually” high numbers of cases in 14 countries during the first quarter of 2024, the advisory said.
The virus typically causes a blotchy rash on the cheeks that appears as if someone has slapped them — hence its nickname, “slapped cheek disease.”
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“Parvovirus can be a very mild infection in many people, but if you are pregnant or are immunocompromised in any way, you are at a much greater risk of serious illness,” Dr. Aaron Glatt, chief of infectious diseases at Mount Sinai South Nassau Hospital on Long Island, New York, told Fox News Digital.
What is parvovirus B19?
Parvovirus B19 is a virus that can be easily spread by respiratory droplets in the air after an infected person coughs or sneezes, according to the CDC.
A respiratory disease known as parvovirus B19 is on the rise in the U.S. among all age groups, according to a recent advisory from the U.S. Centers for Disease Control and Prevention (CDC). (iStock)
Children are often infected at school and spread it to other kids through close personal contact, then later to adults when they come home, experts say.
Approximately 50% of people who were not previously infected contract the virus from an infected family member — while 20% to 50% of susceptible students and staff become infected during school outbreaks, the advisory notes.
“The virus is highly contagious and can spread asymptomatically,” Dr. Marc Siegel, senior medical analyst for Fox News and clinical professor of medicine at NYU Langone Medical Center, told Fox News Digital.
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Parvovirus B12 is also known as “fifth disease” because it was previously listed fifth on a list of common childhood viral illnesses that cause rashes, according to Mayo Clinic.
(The top three on this list are measles, rubella and scarlet fever.)
Symptoms of the virus
Many people who get infected don’t have symptoms, but some will experience sickness, according to the advisory.
About a week after an exposure, susceptible children may complain of flu-like symptoms, including fever, muscle pain and fatigue, which generally last less than a week.
People are most contagious in this early phase of the illness.
The virus typically causes a blotchy rash on the cheeks that appears as if someone has slapped them — hence the nickname “slapped cheek disease.” (iStock)
Several days after the fever starts, children often develop the hallmark blotchy “slapped cheek” rash — a helpful clue that health care providers use to diagnose the illness.
People are generally not infectious by the time they develop the rash, experts say.
A fine, “lacy” rash may follow on the chest, back, buttocks, or arms and legs that is sometimes itchy, according to the CDC. It usually goes away in about a week to 10 days.
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Adults are less likely to develop the “slapped cheek” rash. Their most common symptoms are a generalized rash on the body and joint pain that affects the hands, feet and knees.
In some cases, adults only experience joint pain, which usually lasts one to three weeks – although it can last for months. It usually resolves without long-term complications.
Antibodies provide immunity
Antibodies from prior infection help prevent recurrence of parvovirus B12, the CDC said.
“Once infected, you have a lifetime immunity,” Siegel noted.
The largest increase in infections was among children ages 5 to 9.
Most adults in the United States are immune — with 50% having detectable antibody levels by age 20, and more than 70% acquiring them by age 40, per the advisory.
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The share of people who have had a recent infection dropped below 3% between 2022 and 2024, but increased to 10% in June of this year.
The largest increase in infections was among children ages 5 to 9, going from 15% to 40% in that time frame, the health alert noted.
People who work in settings with close contact with children, such as schools and day cares, are at a greater risk of infection.
High-risk populations
Most healthy adults and children only have a mild illness, but people with weakened immune systems, pregnant women and those with chronic blood disorders can develop serious health complications from this virus, according to the CDC.
“Anyone with those conditions should be very quick to seek out medical attention to help address potential complications,” Glatt noted.
Pregnant women who are susceptible to the virus may spread the illness to their babies, the CDC warned. (iStock)
Pregnant women who are susceptible to the virus may spread the illness to their babies, the CDC warned.
“Unfortunately, there is an increased risk of miscarriage if you get parvovirus during pregnancy,” Glatt said.
Parvovirus infection may lead to adverse outcomes — such as severe anemia in the fetus and miscarriage — in 5% to 10% of cases during pregnancy, with the highest risk at between 9 and 20 weeks of fetal gestation, per the advisory.
While parvovirus B19 can affect humans of all ages, only two out of 10 individuals will have physical symptoms. (iStock)
“There is an increased risk of complications in patients with significant immunocompromising conditions, such as those who have leukemia, have received an organ transplant or have an HIV infection,” Glatt added.
Since most adults are immune to the virus, however, many pregnant women are protected from the virus, the CDC noted.
Treatment is mainly ‘supportive care’
Infected pregnant women primarily receive supportive care, which means treating the underlying symptoms and monitoring for severe fetal anemia, according to the advisory.
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People with weakened immune systems or those with chronic blood disorders can sometimes develop bone marrow failure as a result of the virus, the advisory added.
In that case, treatment often includes blood cell transfusions and intravenous immunoglobulin (IVIG).
People are generally not infectious by the time they develop the rash, experts say. (iStock)
(IVIG is a collection of antibodies that strengthens the immune system, according to Mayo Clinic’s website.)
There is currently no vaccine to prevent parvovirus B19, and most people infected with the virus will recover without any long-term complications.
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“While there is no specific treatment for parvovirus infection, recognizing the complications and addressing them early may be of benefit,” Glatt added.
Hand-washing can also help to prevent transmission, according to Siegel.
Medical expert analyzes trending IV therapy, concerns about peptides
Dr. Mike Varshavski joins ‘Fox & Friends’ for Wellness Week, examining trending self-care treatments. He evaluates IV vitamin therapy, highlighting its hospital-critical role versus unproven benefits for general wellness, citing potential risks like vitamin imbalance. Dr. Mike also differentiates creatine, a research-backed supplement, from unregulated peptides marketed with unverified anti-aging and muscle growth promises, urging caution for patients.
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We are officially living in the “maxxing” era.
From “looksmaxxing” to improve appearance to “sleepmaxxing” for better rest, these viral terms all point to the same goal: squeezing every ounce of potential out of a specific trait or habit.
With a growing focus on optimizing wellness and maximizing longevity, the trend has evolved into what’s known as “humanmaxxing,” sparking a bigger question: How far can people go to optimize the human body?
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While there is no single definition of humanmaxxing, the trend generally refers to efforts to optimize health, performance and longevity through a combination of lifestyle habits, health tracking, supplements and, in some cases, more experimental interventions.
While there is no single definition of humanmaxxing, the trend generally refers to efforts to optimize health, performance and longevity through a combination of lifestyle habits, health tracking, supplements and, in some cases, more experimental interventions. (iStock)
For some, the movement begins with biohacking. According to Dave Asprey, a Texas-based wellness expert who refers to himself as the “father of biohacking,” optimizing your body starts with changing your environment.
Asprey has defined biohacking as “the art and science of changing the environment around you or inside you so that you have full control of your own biology.”
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His public advice focuses on boosting cellular energy through everyday choices like intermittent fasting, high-fat diets, red-light therapy and supplement routines.
“My goal right now is 180 years, because I’m doing something about it now instead of waiting,” he once said.
Clinical experts warn that extreme self-experimentation skips the rigorous safety checks that typical medical science requires. (iStock)
Others have embraced a more data-driven approach. Tech entrepreneur Bryan Johnson, creator of the multimillion-dollar longevity project Blueprint in Los Angeles, argues that optimizing the body means removing human error from health decisions and instead relying on medical data.
“Methodically, we sought to build an algorithm with science and data that could better care for me than I can myself,” Johnson wrote on his website. “My mind did not have the authority to override the algorithm.”
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Johnson’s routine involves tracking hundreds of health metrics, eating a precisely measured diet, taking dozens of supplements, and undergoing advanced medical treatments in an effort to reduce his biological age.
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At the far end of the spectrum are those investing in technologies aimed at pushing the limits of human performance.
London-based tech investor Christian Angermayer recently described humanmaxxing as a strategy toward human maximization.
Tech entrepreneur Bryan Johnson, creator of the multimillion-dollar longevity project Blueprint, argues that optimizing the body means removing human error from health decisions and instead relying on medical data. (iStock)
“I don’t think we should become something different, because I think humans are awesome, but I think we can maximize the potential [that] is already in us,” he said in an interview with The New York Times.
Angermayer’s investment firm, Apeiron Investment Group, focuses on technologies intended to help people “live longer, healthier and more fulfilling lives.” He also founded atai Life Sciences, a biotechnology company that develops psychedelic treatments for mental health conditions that are currently being evaluated in clinical trials.
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As interest in humanmaxxing grows, mainstream health experts urge consumers to separate evidence-based wellness practices from experimental interventions.
Public guidance from the National Institute on Aging notes that while some anti-aging therapies have shown promise in laboratory research, there is not yet sufficient evidence that they can safely extend human life.
As interest in humanmaxxing grows, mainstream health experts urge consumers to separate evidence-based wellness practices from experimental interventions. (iStock)
Clinical experts also caution that extreme self-experimentation can bypass the rigorous safety standards applied to conventional medical treatments.
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According to the Endocrine Society, taking substances such as testosterone or growth hormone without a medical need can lead to serious health risks, including cardiovascular complications and long-term disruption of the body’s chemical balance.
While many humanmaxxing habits overlap with standard healthy lifestyle practices, experts say consumers should be cautious of expensive or experimental interventions that promise dramatic anti-aging or longevity benefits without strong scientific evidence.
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A new test could make it easier to detect high-risk prostate cancer cases earlier.
The blood test, called Stockholm3, is showing promise in clinical trials, beating out the traditional, standard prostate-specific antigen (PSA) test.
In a new study published in the Annals of Internal Medicine, researchers from the Karolinska Institutet in Sweden studied the test’s efficacy in more than 12,000 men — mostly Swedish or European — aged 50 to 74.
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All participants were tested with PSA and Stockholm3 and were followed for two years. During the follow-up period, 443 men were diagnosed with aggressive prostate cancer.
Stockholm3 detected 90% of aggressive prostate cancer cases compared to 74% for PSA tests.
Stockholm3 detected 90% of aggressive prostate cancer cases compared to 74% for PSA tests. (iStock)
Stockholm3 missed “significantly fewer” serious cancer cases than PSA. The number of men incorrectly classified as high-risk was similar across both tests, according to a press release.
Thorgerdur Palsdottir, a researcher at the Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, wrote in a statement that one of the major challenges in prostate cancer is being able to identify the cases that are “truly dangerous.”
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“Our results show that Stockholm3 identifies significantly more aggressive cancer cases than PSA without increasing the number of unnecessary follow-ups,” she said.
“These results point toward a potential change in how prostate cancer screening can be conducted,” the researcher added. “A more precise blood test could enable earlier detection of aggressive disease while reducing the number of unnecessary follow-up examinations and procedures.”
“A more precise blood test could enable earlier detection of aggressive disease while reducing the number of unnecessary follow-up examinations and procedures,” a researcher commented. (iStock)
Study co-author Hari Vigneswaran, chief medical officer of Stockholm3-maker A3P Biomedical, commented on these “promising” findings in an interview with Fox News Digital.
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He confirmed that the PSA has been the standard for prostate cancer screening since the 1990s despite its “well-documented limitations.”
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“It leads to invasive and costly follow-up testing, contributes to over-diagnosis of non-aggressive cancers and, most importantly, it misses a substantial share of aggressive disease,” Vigneswaran said.
When aggressive prostate cancer is found while still confined in the prostate, the five-year survival is close to 100%. (iStock)
When aggressive prostate cancer is found while still confined in the prostate, the five-year survival rate is close to 100%, which highlights the importance of early detection, according to the doctor.
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Data from the National Cancer Institute’s SEER database show that metastatic prostate cancer has risen over the past decade, suggesting that “we have not improved early detection of the aggressive, curable disease that screening is meant to catch,” Vigneswaran said.
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“The goal of screening is to find the cancers that need treatment while they are still curable, without raising the number of men who screen positive but don’t have aggressive disease,” he said.
Stockholm3 could reduce the need for unnecessary MRIs and biopsies, according to the researcher. (Getty Images)
Stockholm3 could reduce the need for unnecessary MRIs and biopsies, according to the researcher.
The findings did have some limitations. Stockholm3 is an investigational device and is not available for sale in the U.S., Vigneswaran noted.
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The test estimates a man’s risk of aggressive prostate cancer, but a biopsy remains the gold standard for confirming the disease.
The company plans to seek FDA approval to use the test for routine screening and will “generate the evidence needed to support that pathway, including U.S. data,” Vigneswaran said.
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