Health
Multiple myeloma, rare blood cancer: Bruce Springsteen's wife's diagnosis spotlights the illness
Patti Scialfa, Bruce Springsteen’s wife and a member of the E Street Band, recently shared that she was diagnosed in 2018 with a type of blood cancer called multiple myeloma.
She revealed her illness in the documentary “Road Diary: Bruce Springsteen and the E Street Band,” which premiered at the Toronto Film Festival on Sept. 8.
The production gives a behind-the-scenes look at the famed musician and the long-standing band during their latest tour.
BRUCE SPRINGSTEEN’S WIFE ANNOUNCES BLOOD CANCER DIAGNOSIS
“This affects my immune system, so I have to be careful what I choose to do and where I choose to go,” Scialfa, 71, said in the film when discussing her illness.
Patti Scialfa, Bruce Springsteen’s wife and a member of the E Street Band, recently shared that she was diagnosed in 2018 with a type of blood cancer called multiple myeloma. (Getty Images)
“Every once in a while, I come to a show or two and I can sing a few songs on stage, and that’s been a treat,” she continued.
Scialfa joined the E Street Band right before the 1984 “Born in the U.S.A.” tour. She later married Springsteen in 1991 and was inducted into the Rock and Roll Hall of Fame in 2014.
Fox News Digital reached out to Scialfa for comment.
What is multiple myeloma?
Multiple myeloma, a cancer of the cells in the bone marrow, is diagnosed in more than 35,000 people in the U.S. each year, according to the American Cancer Society.
Plasma cells grow in the bone marrow, which has been described as a “factory” of blood.
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In a healthy person, the cells produce proteins called antibodies that are directed against germs to fight infection, according to Dr. Cristina Gasparetto, a hematologic oncologist and professor of medicine at Duke University School of Medicine.
Multiple myeloma occurs when plasma cells grow “out of control,” the ACS states.
Multiple myeloma occurs when plasma cells grow “out of control,” per the American Cancer Society. (iStock)
That causes abnormal antibodies to be secreted in the blood, which can damage the bones and other organs.
“[The disease] is called ‘multiple’ because there are frequently multiple patches or areas in the bone where it grows,” Dr. Joseph Mikhael, chief medical officer of the International Myeloma Foundation in California, told Fox News Digital.
Symptoms of the disease
“Most of the signs and symptoms of myeloma are rather general, with the top three being excessive fatigue, bone pain and anemia,” Mikhael said.
Some patients, however, may not have any symptoms when they are diagnosed.
The most common symptoms can be summed up in the acronym “CRAB,” which stands for high calcium levels in the blood, renal (or kidney) insufficiency, anemia and bone destruction, experts say.
The top three symptoms of the disease are excessive fatigue, bone pain and anemia, experts say.
Bone pain is the hallmark of the disease, as the myeloma cells grow within the bone, which may lead to elevated levels of calcium in the blood, Gasparetto told Fox News Digital.
“Symptoms of having high calcium include increased thirst, dehydration, fatigue, muscle pain and sometimes confusion,” she added.
Multiple myeloma is diagnosed in more than 35,000 people in the U.S. each year, according to the American Cancer Society. (iStock)
The antibodies produced by the myeloma cells are eliminated through the kidneys, which can cause obstruction and/or direct damage to the organs.
“The patient will notice some foamy urine, due to the presence of an abundant amount of an [abnormal] protein called Bence-Jones proteinuria,” Gasparetto said.
Methods of diagnosis
The first step is typically to administer specific blood and urine tests, which reveal abnormally high protein levels excreted by the tumor cells – often referred to as an “M spike,” experts told Fox News Digital.
“We measure this protein at the time of diagnosis, during therapy to assess response, and thereafter to monitor progression or relapse,” Gasparetto said.
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Bone pain may also prompt imaging, which would reveal any skeletal abnormalities.
The initial results are then confirmed with a bone aspiration and biopsy.
“With the bone marrow aspiration, we remove a small amount of fluid from the bone marrow, and with the bone marrow biopsy, we remove a small piece of bone,” Gasparetto said.
Myeloma does not typically run in families, but there is a slightly increased incidence when a family member has the disease, experts say. (iStock)
A pathologist then analyzes the sample to determine the severity of the disease.
The final diagnosis is based on a combination of all these tests — blood work, bone marrow aspiration and biopsy, imaging studies and urinalysis, experts told Fox News Digital.
Risk factors for the disease
Myeloma does not typically run in families, but there is a slightly increased incidence when a family member has the disease, Mikhael told Fox News Digital.
“For the vast majority of cases, we do not know the cause of myeloma.”
Many cases may be due to random genetic changes that occur later in life, experts say.
“For the vast majority of cases, we do not know the cause of myeloma,” Mikhael said. “It is more common as we age, with the average age of diagnosis approximately 69.”
African-American and Latino American patients are diagnosed at a younger age, on average at around 64 or 65.
Individuals of African descent are twice as likely to have myeloma, statistics show.
Multiple myeloma is more common as people age, doctors say, with the average age of diagnosis approximately 69. (iStock)
Firefighters who have been exposed to fires are more at risk, and other types of chemical exposures are also connected to myeloma, including Agent Orange and excessive radiation, Mikhael noted.
There may also be a greater risk for people who have a higher increased body mass index, as well as in people who have certain blood conditions, such as monoclonal gammopathy of undetermined significance (MGUS), which involves an abnormal protein in the blood without the organ damage caused by multiple myeloma.
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In most cases, multiple myeloma cannot be prevented, according to Dr. Mikkael Sekeres, chief of the division of hematology of Sylvester Cancer Center at the University of Miami.
Treatment options
The American Cancer Society recommends that myeloma patients see an oncologist for a personalized treatment plan based on their age, overall health and severity of the disease.
Some therapies may include monoclonal antibodies and drugs called immune modulating agents, which boost the immune system to help the body fight cancer.
“Multiple myeloma can [also] be treated with chemotherapy — up to three or four drug regimens for a few months, followed by maintenance therapy,” a doctor said. (iStock)
“Multiple myeloma can [also] be treated with chemotherapy — up to three or four drug regimens for a few months, followed by maintenance therapy,” Sekeres told Fox News Digital.
Eligible patients may pursue a bone marrow (stem cell) transplant, which can lead to prolonged remissions, the doctor added.
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The cancer is not cured with conventional therapy, but most patients respond well to treatment, according to Mikhael.
“The average survival rate was one or two years just 20 years ago, but it is now over 10 years,” he noted.
Health
Brain Health Challenge: Doctor Appointments for Your Mind and Body
Congratulations, you’ve reached the final day of the Brain Health Challenge! Today, we’re asking you to do a few things that might feel a bit out of left field — like getting your blood pressure checked.
No, it isn’t as fun as playing Pips, but experts say it’s one of the most important things you can do for your brain. That’s because heart health and brain health are intrinsically linked.
High blood pressure, in particular, can damage brain cells, and it’s a significant risk factor for stroke and dementia. When blood pressure is too high, it places stress on the walls of arteries in the brain. Over time, that added stress can cause the blood vessel walls to thicken, obstructing blood flow. In other cases, the increased pressure causes the artery walls to thin and leak blood into the brain.
These changes to the blood vessels can sometimes cause a large stroke to occur. More commonly, the damage leads to micro-strokes and micro-hemorrhages, which cause fewer immediate problems and often go unnoticed. But if someone has hypertension for years or decades, these injuries can build up, and the person may start to experience cognitive impairment.
High blood pressure “is known as a silent killer for lots of reasons,” said Dr. Shyam Prabhakaran, the chair of neurology at the University of Chicago. “It doesn’t cause you any symptoms until it does.”
Because the damage accumulates over many years, experts say that managing blood pressure in midlife matters most for brain health. Hypertension can be addressed with medication or lifestyle changes, as directed by your doctor. But the first thing you need to do is know your numbers. If your blood pressure comes back higher than 120/80, it’s important to take it seriously, Dr. Prabhakaran said.
While you’re at it, there are a few other aspects of your physical health that you should check on.
Your eyes and ears are two of them. Hearing and vision loss have both been shown to increase the risk of dementia. Experts think that with less sensory information coming in to stimulate the brain, the regions that process hearing and vision can start to atrophy. What’s more, people with sensory loss often withdraw or are left out of social interactions, further depriving them of cognitive stimulation.
Oral health can also affect your brain health. Research has found a connection between regular flossing and reduced odds of having a stroke. That may be because good oral health can help to reduce inflammation in the body. The bacteria that cause gum disease have also been tied to an increased risk of Alzheimer’s.
And have you gotten your shingles vaccine? There is mounting evidence that it’s a powerful weapon for protecting against dementia. One study found that it lowered people’s odds of developing the condition by as much as 20 percent.
To wrap up this challenge, we want you to schedule a few medical appointments that benefit your brain, as well as your body.
After five days of feeding, exercising and challenging your brain, you are well on your way to better cognitive health. Thanks for joining me this week, and keep up the good habits!
Health
Health experts react as Andrew Huberman backs Trump admin’s new food pyramid
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The Trump administration has taken a new approach to the food pyramid.
The Department of Health and Human Services (HHS) announced new guidelines on Wednesday with an updated, inverted pyramid. The top of the pyramid, which is now the wider part of the structure, is built on meat, fats, fruits and vegetables, while whole grains are at the narrow bottom.
This follows HHS Secretary Robert F. Kennedy Jr.’s mission to “Make America Healthy Again” (MAHA), aimed at addressing chronic disease, childhood illnesses and ultraprocessed foods.
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“The new guidelines recognize that whole, nutrient-dense food is the most effective path to better health and lower health care costs,” Kennedy said during a press briefing in Washington, D.C.
“Protein and healthy fats are essential, and were wrongly discouraged in prior dietary guidelines. We are ending the war on saturated fats.”
The Trump administration announces the 2025-2030 Dietary Guidelines for Americans, putting “real food” back at the center of health. (realfood.gov)
The HHS secretary rallied against refined carbohydrates, food additives and added sugar, highlighting the health risks associated with sugar-sweetened beverages.
Kennedy’s main message to Americans was to “eat real food.”
TRUMP ADMIN’S NEW NUTRITION GUIDELINES TARGET ULTRA-PROCESSED FOODS, EASE UP ON RED MEAT AND SATURATED FATS
The announcement triggered reactions from top health and wellness voices, including Stanford neuroscientist Dr. Andrew Huberman, host of the “Huberman Lab” podcast.
In a post on X, Huberman shared the White House’s graphic of the new pyramid, praising the decisions that were made.
“Oatmeal (and I think that’s rice and sourdough) made the cut!” he commented. “In all seriousness, assuming overall calories are kept in check and people exercise & get sun(day)light, this looks spot on.”
He added, “Maybe up the veggies a bit, add low-sugar fermented foods like sauerkraut & this is great.”
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Huberman said in a thread on the same post that Americans “don’t have to eat all the foods” shown in the diagram.
“You won’t see me drinking milk or eating shrimp,” he said. “Nothing against shrimp, I just don’t like the taste. Aversion to crustaceans.”
“Maybe up the veggies a bit, add low-sugar fermented foods like sauerkraut & this is great,” Huberman commented on X. (Chance Yeh/Getty Images for HubSpot; iStock)
The new guidelines received praise from other major health figures, including former FDA commissioner Dr. David Kessler.
“There should be broad agreement that eating more whole foods and reducing highly processed carbohydrates is a major advance in how we approach diet and health,” Kessler told The Associated Press.
“Protein and healthy fats are essential, and were wrongly discouraged in prior dietary guidelines.”
Dr. Bobby Mukkamala, president of the American Medical Association, shared in a statement that these guidelines “affirm that food is medicine and offer clear direction patients and physicians can use to improve health.”
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“The American Medical Association applauds the Administration’s new Dietary Guidelines for spotlighting the highly processed foods, sugar-sweetened beverages and excess sodium that fuel heart disease, diabetes, obesity and other chronic illnesses,” Mukkamala wrote.
The American Medical Association applauded the HHS for its updated nutrition guidelines. (iStock)
But not all feedback was positive.
Some people expressed concern about prioritizing red meat and dairy, while calling for the limitation of saturated fat.
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Neal Barnard, president of the Physicians Committee for Responsible Medicine, shared in a reaction to STAT that while the guidelines “do have one or two good points, emphasizing fruits and vegetables and limiting alcohol,” the guidelines are “for the most part a strong reflection of industry influence.”
Christopher Gardner, a nutrition expert at Stanford University, also spoke out against the new guidelines, as reported by NPR.
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“I’m very disappointed in the new pyramid that features red meat and saturated fat sources at the very top, as if that’s something to prioritize. It does go against decades and decades of evidence and research,” said Gardner, who was a member of the Dietary Guidelines Advisory Committee.
Fox News Digital’s Rachel Wolf, as well as Alexandria Hoff of Fox News, contributed reporting.
Health
Matt Damon’s Gluten-Free Diet Helped Him Lose 18 Pounds
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