Health
Hidden belly fat could signal Alzheimer’s disease risk 15 years before symptoms show up, study finds
Even if you can’t see it, fat buried deep within the belly can increase the risk of Alzheimer’s disease.
That’s according to research released by the Radiological Society of North America (RSNA) on Monday.
Visceral fat, which surrounds the internal organs in the belly, has been linked to brain changes that could point to future dementia in people as young as 50, up to 15 years before symptoms appear, as noted in a press release from RSNA.
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The findings, published in the journal Aging and Disease, will be presented at the RSNA’s annual meeting next week.
Researchers analyzed the brain MRIs and PET scans of 54 “cognitively healthy” participants between the ages of 40 and 60, focusing on any inflammation and “plaques and tangles” that are typically seen in Alzheimer’s patients.
They also assessed the middle-aged adults’ body mass index (BMI), obesity levels, blood glucose and abdominal fatty tissue.
“Even though there have been other studies linking BMI with brain atrophy or even a higher dementia risk, no prior study has linked a specific type of fat to the actual Alzheimer’s disease protein in cognitively normal people,” said study author Mahsa Dolatshahi, M.D., post-doctoral research fellow with the Mallinckrodt Institute of Radiology (MIR) at Washington University School of Medicine in St. Louis, in the release.
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“Similar studies have not investigated the differential role of visceral and subcutaneous fat, especially in terms of Alzheimer’s amyloid pathology, as early as midlife.”
The researchers found that those with more visceral fat also had higher levels of amyloid in the precuneus cortex, which is the region of the brain that usually shows the earliest signs of Alzheimer’s disease.
They also had greater inflammation in the brain.
Men were more likely to show this correlation than women.
“We found the hidden fat-Alzheimer biomarker connection in persons at midlife — 40s and 50s — on average 15 years before the earliest symptoms of Alzheimer’s typically appear,” Raji added.
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Visceral fat may also lead to inflammation in the brain, one of the main mechanisms that contribute to Alzheimer’s disease, according to the researchers.
Looking ahead, the hope is that these findings can be a springboard to new targeted treatments.
“We found the hidden fat-Alzheimer biomarker connection in persons at midlife — 40s and 50s — on average 15 years before the earliest symptoms of Alzheimer’s typically appear,” Raji added.
Visceral fat may also lead to inflammation in the brain, one of the main mechanisms contributing to Alzheimer’s disease, according to the researchers.
Looking ahead, the hope is that these findings can be a springboard to new targeted treatments.
“By moving beyond body mass index in better characterizing the anatomical distribution of body fat on MRI, we now have a uniquely better understanding of why this factor may increase risk for Alzheimer’s disease,” said Raji.
Dr. Marc Siegel, clinical professor of medicine at NYU Langone Medical Center and a Fox News medical contributor, was not involved in the study but said the findings aligned with his expectations.
“This is because belly fat is filled with inflammation,” he told Fox News Digital.
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“Cytokines and interleukin 6 (inflammatory proteins) not only lead to heart disease, but there is increasing evidence that this inflammation also leads to neurodegenerative disease and poor brain cell function, and can accelerate Alzheimer’s,” Siegel added.
“This study reinforces that association.”
The main limitation of the research is the small sample size and the fact that it’s a cross-sectional study, Raji noted.
“We are recruiting more participants for this study and want to do a longitudinal version of this work in the future,” he said.
The hope is that the research will help to raise awareness that body and brain health are linked, Raji added.
More than six million Americans are living with Alzheimer’s disease, according to the Alzheimer’s Association.
This number is expected to approach 13 million by 2050.
One in every five women and one out of 10 men will develop the common form of dementia in their lifetime.
For more Health articles, visit www.foxnews.com/health.
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Health
'I'm a psychologist — here's how to finally break your bad habits’
More than a third of Americans report making New Year’s resolutions, statistics show, many of which are focused on kicking bad habits.
Whether it’s smoking, overeating, drinking excessive alcohol or “doom-scrolling” on social media instead of sleeping, 72% of U.S. adults report having at least one unhealthy behavior, according to data from the United Health Foundation.
Dr. Adi Jaffe, a California-based psychologist, knows firsthand the dangers of unhealthy habits, as he once struggled with drug addiction himself.
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“I got trapped in the world of drugs and alcohol, from the middle of high school until a few years after college,” he shared with Fox News Digital during an on-camera interview.
“Addiction doesn’t separate by gender or age or race or income — people from all walks of life are impacted.”
Jaffe ultimately spent time in jail before getting clean and returning to school, earning two master’s degrees and a PhD in psychology.
“I wanted to understand what happened to me — and then what I’ve done over the last 15 years, hopefully, is bring those lessons to others who are struggling.”
“Addiction doesn’t separate by gender or age or race or income — people of all walks of life are impacted.”
Today, Jaffe focuses on helping people beat addiction and improve their mental health. In his upcoming book — “Unhooked: Free Yourself from Addiction Forever” — he shares a step-by-step program to help people free themselves from harmful habits.
Jaffe shared with Fox News Digital some of his tips and insights.
Recognizing the behavior
While many people think of addiction as involving drugs or alcohol, Jaffe noted that it can take many forms.
“If you engage in a behavior of any sort over long periods of time that robs you of your ability to be fully present in your life — and it bothers you, but you can’t find yourself stopping it, even though you’ve tried over and over — to me, that qualifies,” he said.
In addiction to substance abuse, addictive behaviors might include “doom-scrolling” on your phone for hours a day, binge-eating, gambling or indulging in other unhealthy activities.
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People can be addicted to work and success, too, Jaffe noted.
“When things get hard and get tough, they want to go to work,” he said. “They believe success or performance will make them feel better, but it can cause damage just like other addictions.”
Social media is another form of addiction, the expert said.
“When your phone buzzes or pings, you don’t know what’s there, so it’s a novelty that’s interesting, and it releases dopamine,” he said. “You almost literally cannot help yourself.”
Identifying the ‘hooks’
Many people assume that the behavior itself is the problem, Jaffe said — but there is almost always an underlying reason for those unhealthy or harmful choices.
“The behavior was actually a medicine of sorts for a problematic undercurrent.”
“The reason you do it is that at some point earlier in your life, there was pain or struggle or emotional discomfort,” he said.
“And you discovered that when you engaged in the behavior, that discomfort went away. So the behavior was actually a medicine of sorts for a problematic undercurrent.”
For Jaffe, when he was 14 or 15 years old, his “hook” was social anxiety.
“And when somebody handed me a bottle of vodka at some sleepaway camp, I drank it because I didn’t want to look awkward,” he told Fox News Digital.
“Once I started drinking, I had no anxiety and felt like I belonged. I felt like I could talk to people. And so I realized that alcohol had ‘solved’ this problem.”
Everyone has different hooks, Jaffe said, but there are similarities and patterns.
“We start living our lives trying to escape the discomfort of the hooks.”
Replacing the habit
Once people have identified an unhealthy behavior, one of the biggest mistakes they make is just trying to stop it without a plan, according to Jaffe.
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“We try to stop ourselves from doing what we don’t like,” he noted. “Especially around New Year’s, people might say, ‘I’m going to stop eating bad foods or I’m going to stop being lazy,’” he said.
Research has shown, however, that the most important aspect of kicking a bad habit is to replace the negative behavior with a positive one, the psychologist noted.
“We have to stop trying to just eliminate bad habits — it doesn’t work,” Jaffe said. “We have to replace them with something else.”
For example, if someone wants to quit smoking, they might keep gum or sunflower seeds in their pocket, he said.
“You just have to keep going.”
Or, if someone is too focused on work, that might mean letting go of some tasks and delegating them to other people.
Jaffe also emphasized that the process of kicking a bad habit isn’t always perfect or seamless, and that slipping up from time to time doesn’t equate to failure.
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“It’s okay to fall flat on your face a number of times while you’re working on changing this,” he said.
“You just have to keep going.”
Jaffe’s book, “Unhooked: Free Yourself from Addiction Forever,” will be available on Jan. 7.
Health
Warding off dementia means more reading, praying and listening to music: study
For long-term brain health, older adults might want to carefully consider how they spend their downtime, according to a new study.
Researchers from the University of South Australia assessed the 24-hour activity patterns of nearly 400 people over age 60.
When it comes to brain health, the study found that the context or type of activity individuals engage in matters, news agency SWNS reported.
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Some sedentary behaviors are better for cognitive function than others, according to the findings, which were published in The Journal of Gerontology Series A.
Mentally stimulating behaviors, such as reading, listening to music, praying, crafting and playing a musical instrument — as well as social behaviors like chatting with others — are beneficial for memory and thinking abilities, the study noted.
The research team referred to the “valuable insights” that could help reduce instances of cognitive impairment. More passive activities, like playing video games or watching TV, do not offer the same benefits as reading, praying and other activities, they noted.
More than 55 million people around the globe have dementia, according to estimates from the World Health Organization. Another 10 million new cases are diagnosed each year.
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Dr. Maddison Mellow, researcher at the University of South Australia, said that not all sedentary behaviors are equal when it comes to memory and cognitive health.
“In this research,” she said, “we found that the context of an activity alters how it relates to cognitive function, with different activities providing varying levels of cognitive stimulation and social engagement.”
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She said that scientists “already know that physical activity is a strong protector against dementia risk, and this should be prioritized if you’re trying to improve your brain health,” as SWNS reported.
“Even small, 5-minute time swaps can help.”
“But until now, we hadn’t directly explored whether we can benefit our brain health by swapping one sedentary activity for another.”
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She went on, “And while the ‘move more, sit less’ message certainly holds true for cardiometabolic and brain health, our research shows that a more nuanced approach is needed when it comes to thinking about the link between sedentary behaviors and cognitive function.”
It’s wise to “prioritize movement that’s enjoyable and gets the heart rate up,” she also said.
And “even small, 5-minute time swaps can help.”
A recent study published by the RAND Corporation in California also identified several major predictors occurring around age 60 that could likely lead to cognitive impairment and dementia in individuals by age 80, as Fox News Digital previously reported.
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Researchers evaluated 181 potential risk factors, including demographics, socioeconomic status, lifestyle and health behaviors, health history, psycho-social factors and more.
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The list of predictors, according to RAND, included “never exercising” and “low engagement in hobbies.”
The study results suggested that “maintaining good physical and mental health is beneficial not just to staying in shape, but also to staying sharp and delaying cognitive decline,” study co-author Peter Hudomiet, a RAND economist in California, told Fox News Digital.
Melissa Rudy of Fox News Digital contributed reporting.
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