Health
David Paton, Creator of Flying Eye Hospital, Dies at 94
David Paton, an idealistic and innovative ophthalmologist who started Project Orbis, converting a United Airlines jet into a flying hospital that took surgeons to developing countries to operate on patients and educate local doctors, died on April 3 at his home in Reno, Nev. He was 94.
His death was confirmed by his son, Townley.
The son of a prominent New York eye surgeon whose patients included the Shah of Iran and the financier J. Pierpont Morgan’s horse, Dr. Paton (pronounced PAY-ton) was teaching at the Wilmer Eye Institute at Johns Hopkins University in the early 1970s when he became discouraged by increasing cases of preventable blindness in far-flung places.
“More eye doctors were needed,” he wrote in his memoir, “Second Sight: Views from an Eye Doctor’s Odyssey” (2011), “but equally important was the need to beef up the existing doctors’ medical education.”
But how?
He considered shipping trunks of equipment — almost the way a circus would — but that presented logistical challenges. He pondered the possibility of using a medical ship like the one that Project Hope, a humanitarian group, sent around the world. That was too slow for him.
“Shortly after the first moon landing in 1969, thinking big was becoming a reality,” Dr. Paton wrote.
And then a moonshot idea struck him: “Could an aircraft be the answer? A large enough aircraft could be converted into an operating theater, a teaching classroom and all the necessary facilities.”
All he needed was a plane. He asked the military to donate one, but that was a nonstarter. He approached several universities for the money to buy one, but administrators turned him down, saying the idea wasn’t feasible.
“David was willing to take risks that others wouldn’t,” Bruce Spivey, the founding president of the American Academy of Ophthalmology, said in an interview. “He was charming. He was inspiring. And he didn’t quit.”
Dr. Paton decided to raise funds on his own. In 1973, he founded Project Orbis with a group of wealthy, well-connected society figures like the Texas oilman Leonard F. McCollum and Betsy Trippe Wainwright, the daughter of the Pan American World Airways founder Juan Trippe.
In 1980, Mr. Trippe helped persuade the United Airlines chief executive Edward Carlson to donate a DC-8 jet. The United States Agency for International Development contributed $1.25 million to convert the plane into a hospital with an operating room, recovery area and a classroom equipped with televisions, so local medical workers could watch surgeries.
Surgeons and nurses volunteered their services, agreeing to spend two to four weeks abroad. The first flight, in 1982, was to Panama. The plane then went to Peru, Jordan, Nepal and beyond. Mother Teresa once visited. So did the Cuban leader Fidel Castro.
In 1999, The Sunday Times of London’s magazine sent a reporter to Cuba to write about the plane, now known as the Flying Eye Hospital. One of the patients who arrived was a 14-year-old girl named Julia.
“In developed nations, Julia’s condition would have been little more than an irritation,” The Sunday Times article said. “It is almost certain she had uveitis, an inflammation inside the eye, which can be cleared with drops. In Britain, even cats are easily treated.”
Her doctor was Edward Holland, a prominent eye surgeon.
“Holland uses tiny knives to make openings that allow him to get his instruments into the eye, and soon he is pulling at Julia’s scar tissue,” The Sunday Times article said. “As the tissue is pulled away, a dark and liquid pupil, unseen for a decade, is revealed. It is an intimate and moving moment; this is medicine’s chamber music. Next, he breaks up and removes the cataract, and implants a lens so that the eye will keep its shape.”
The Cuban ophthalmologists watching in the viewing room applauded.
But after the surgery, Julia still couldn’t see.
“And then a minor miracle begins,” the article said. “As the swelling begins to go down, she makes discoveries about the world around her. Minute by minute she can see something new.”
David Paton was born on Aug. 16, 1930, in Baltimore, and grew up in Manhattan. His father, Richard Townley Paton, specialized in corneal transplants and founded the Eye-Bank for Sight Restoration. His mother, Helen (Meserve) Paton, was an interior designer.
In his memoir, he described growing up “among the fine, intellectually sharp, widely traveled persons of the Establishment.” His father practiced on Park Avenue. His mother threw parties at their home on the Upper East Side.
David attended the Hill School, a boarding school in Pottstown, Pa. There, he met James A. Baker III, a Texan who later became secretary of state for President George H.W. Bush. They were roommates at Princeton University and lifelong best friends.
“David came from a very privileged background, but he was down to earth and just a very likable guy,” Mr. Baker said in an interview. “He had his objectives in life straight. He was a hell of a lot better student than I was.”
After graduating from Princeton in 1952, David earned his medical degree from Johns Hopkins University. He worked in senior positions at the Wilmer Eye Institute and served as chairman of the ophthalmology department at the Baylor College of Medicine in Houston.
In 1979, while still trying to procure a plane for Project Orbis, he became the medical director of the King Khaled Eye Specialist Hospital in Riyadh, Saudi Arabia.
“Among my duties,” he wrote in his memoir, “was providing eye care for many of the princes and princesses of the kingdom — about 5,000 of each, I was told — and it seemed that all of them insisted on being treated exclusively by the doctor in charge, no matter how minor their complaint.”
Dr. Paton’s marriages to Jane Sterling Treman and Jane Franke ended in divorce. He married Diane Johnston in 1985. She died in 2022.
In addition to his son, he is survived by two granddaughters.
Dr. Paton left his role as medical director of Project Orbis in 1987, after a dispute with the board of directors. That year, President Ronald Reagan awarded him the Presidential Citizens Medal.
Although his official connection with the organization had ended, he occasionally served as an informal adviser.
Now called Orbis International, the organization is on its third plane, an MD-10 donated by Federal Express.
From 2014 to 2023, Orbis performed more than 621,000 surgeries and procedures, according to its most recent annual report, and offered more than 424,000 training sessions to doctors, nurses and other providers.
“The plane is just such a unique venue,” Dr. Hunter Cherwek, the organization’s vice president of clinical services and technologies, said in an interview. “It was just an incredibly bold and visionary idea.”
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The sudden death of Kyle Busch has drawn attention to a rare but devastating medical progression: when pneumonia escalates into fatal sepsis.
An ER doctor spoke with Fox News Digital about how sepsis can trigger a rapid health decline.
“Sepsis is actually not a specific disease or diagnosis, but rather the syndrome that occurs when the body has certain abnormal findings and a presumed infection,” said Dr. Kenneth J. Perry, a South Carolina-based emergency medicine physician.
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The markers of sepsis include elevated white blood cell counts, a high or low temperature, and elevated heart and respiratory rates, according to Perry. Because of this, a patient with pneumonia is often already technically septic by definition.
In the wake of Kyle Busch’s sudden passing, there is a focus on the rapid decline from pneumonia to fatal sepsis. (Getty; iStock)
While many people assume a worsening infection means bacteria are multiplying uncontrollably, it often has more to do with the body’s internal environment.
“It is often not the bacteria itself that is causing the specific decline,” Perry said. “In most cases, it is a cascade of inflammatory processes that are set in motion by the infection.”
When this inflammation spirals out of control, the body moves from having a manageable infection into severe sepsis. This is when otherwise healthy people can rapidly deteriorate.
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“The concerning thing that can happen with any individual … is that sepsis can then lead to low blood pressure, worsening vital signs and organ damage,” Perry said.
“As multiple organs fail, it becomes very difficult for the medical team to treat and can sometimes lead ultimately to death.”
“The medical evaluation provided to the Busch Family concluded that severe pneumonia progressed into sepsis, resulting in rapid and overwhelming associated complications,” the family shared in a statement. (James Gilbert/Getty Images)
It is very unlikely to have pneumonia and not have any symptoms, according to Perry. Early signs can mimic a severe flu, including fevers, chills, a productive cough, and chest or back pain in cases where the lung is infected.
When sepsis begins to take hold, time becomes the most critical factor. “We have known for a number of years that early antibiotic therapy is beneficial in the treatment of sepsis,” Perry said.
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If you or a loved one are managing an infection at home, the doctor says the following red flags mean you should bypass the clinic and head straight to the emergency room.
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- Shortness of breath or difficulty breathing
- A racing heart rate or fever that continues to worsen even after starting treatment
- Severe chest pain associated with a productive cough
The slide into sepsis is, in most cases, a cascade of inflammatory processes that are set in motion by the infection, the doctor said. (iStock)
While cases like Busch’s are tragic, Perry stressed that this shouldn’t cause widespread panic. Most patients with pneumonia do very well with standard oral antibiotics.
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The NASCAR star’s rapid decline underscores the importance of medical vigilance and “having a primary care physician with whom you have a good relationship,” according to the ER doctor.
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“Monitoring symptoms while having easy access to primary care is a very beneficial and appropriate plan for most patients,” he added.
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Popular glucagon-like peptide-1 (GLP-1) weight-loss drugs may help slow the spread of some cancers, according to new research to be presented at a major medical conference.
Research led by Cleveland Clinic found that the medications may reduce the spread of several obesity-related cancers, including lung, breast, colorectal and liver cancers.
The findings will be presented at the 2026 ASCO Annual Meeting next week in Chicago.
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According to a press release, the real-world retrospective study included 12,112 patients with the following types of obesity-related cancers, ranging from stage 1 to stage 3.
Popular GLP-1 weight-loss drugs may help slow the spread of some cancers, according to new research to be presented at a major medical conference. (iStock)
- Breast adenocarcinoma
- Prostate adenocarcinoma
- Non-small cell lung cancer (NSCLC)
- Colorectal adenocarcinoma
- Hepatocellular carcinoma (liver cancer)
- Renal cell carcinoma
- Pancreatic adenocarcinoma
Half of the participants started a GLP-1 medication – semaglutide, tirzepatide, dulaglutide, liraglutide, lixisenatide or pramlintide – after their cancer diagnosis.
The other half began taking a DPP-4 inhibitor comparator “gliptins,” a different class of diabetes medications, the study noted.
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Compared to the patients taking gliptins, the GLP-1 users were found to have significantly lower progression to stage 4 disease for four types of cancers.
The biggest risk reduction was for non-small cell lung cancer (50%), followed by breast cancer (43%), colorectal cancer (31%) and liver cancer (38%).
Compared to the patients taking gliptins, the GLP-1 users were found to have significantly lower progression to stage 4 disease for four types of cancers. (iStock)
“Our study found that use of GLP-1 drugs, compared to DPP-4 inhibitors and other antidiabetic drugs, was associated with a meaningful reduction in cancer progression across four solid tumor types,” said lead study author Mark David Orland, MD, of the Taussig Cancer Institute at Cleveland Clinic, in the release. “It provides early evidence that future studies are worth pursuing.”
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Three other types of cancer – prostate, pancreatic and kidney – also had lower rates of spread among those taking GLP-1s, but those differences were “not statistically significant,” the researchers noted.
“Our study found that use of GLP-1 drugs … was associated with a meaningful reduction in cancer progression across four solid tumor types.”
Tumors with higher levels of GLP-1 receptors — proteins that help cells respond to GLP-1 hormones and drugs — were also linked to better survival outcomes, according to the study findings.
Overall, patients whose tumors had more of these receptors were about one-third less likely to die during the study period.
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The incidence of adverse side effects was similar between GLP-1 and gliptin groups.
The findings suggest that GLP-1 pathways may directly influence how some cancers grow or spread, though researchers say more studies are needed to understand the mechanism behind this effect.
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The study, which has not yet been peer-reviewed, had some limitations, according to the researchers. As it was retrospective and observational in design – as opposed to a randomized clinical trial – it couldn’t prove that GLP-1 drugs directly prevent cancer progression.
The findings suggest that GLP-1 pathways may directly influence how some cancers grow or spread, though researchers say more studies are needed to understand the mechanism behind this effect. (iStock)
Other factors, such as participants’ health conditions, weight loss and metabolic improvements, may have influenced the results, researchers noted.
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For some specific cancer types, there may not have been enough patients represented to detect statistically significant differences.
Further randomized clinical trials are needed to evaluate these preliminary findings and to determine the specific ways in which GLP-1s control cancer progression.
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