Health
Cosmetic fillers can cause deadly complication, experts warn — but new tech exposes it
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Each year, more than 5 million cosmetic filler procedures are performed in the U.S. — but these injectables can potentially block key blood vessels, putting patients at risk for serious harm.
In a study presented this week at the annual meeting of the Radiological Society of North America (RSNA) in Chicago, doctors found that ultrasound technology can spot these dangerous blockages early enough to guide treatment and help prevent lasting injury.
The researchers looked at data from 100 patients from six different locations who experienced vascular complications after hyaluronic acid filler injections. All data were collected between May 2022 and April 2025, according to a press release.
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They found that ultrasounds successfully detected vascular occlusion, which is a blockage in a blood vessel that stops normal blood flow.
If this condition goes untreated, it can cause pain, skin damage and scarring — and, in severe cases, vision loss or stroke.
Each year, more than 5 million cosmetic filler procedures are performed in the U.S. — but these injectables can potentially block key blood vessels. (iStock)
“Doppler ultrasound helps doctors see exactly where the filler is, how the blood is flowing in real time, and whether blood vessels may have been affected after a cosmetic procedure,” lead researcher Rosa Maria Silveira Sigrist, M.D., attending radiologist at the University of São Paulo in Brazil, told Fox News Digital.
“The physical exam continues to be very important, but the ultrasound adds extra information that makes the evaluation safer and the treatment more precise.”
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In the study, more than 40% of patients had blockages in the perforator vessels, which are small connecting blood vessels, while 35% had major facial arteries that showed no blood flow.
The nasal region was identified as the highest-risk area, as the lateral nasal artery runs along the side of the nose and supplies blood to larger arteries that lead toward the eye and the brain.
Doctors found that ultrasound technology can spot dangerous blockages early enough to guide treatment and help prevent lasting injury. (iStock)
“Vascular occlusion after filler injections can lead to devastating outcomes, including skin necrosis, tissue loss, and — in the worst cases — blindness and even stroke,” Dr. Anthony Berlet, a board-certified plastic surgeon in New Jersey, who was not involved in the research, told Fox News Digital.
“Once a critical artery — for example, one feeding the retina or skin — is occluded by filler or embolus, the damage may be irreversible.”
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In the hands of an experienced, licensed professional using proper techniques, the risk of a vascular occlusion should be less than 1%, according to Dr. Samuel Golpanian, a double board-certified plastic surgeon in Beverly Hills.
“But if fillers are done by someone untrained or using the wrong needles or methods, the complication rate can be much higher — 10% to 20%, which is completely unacceptable,” Golpanian, who also did not work on the study, told Fox News Digital.
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Ultrasound helped doctors pinpoint the locations of the blockages, allowing them to place a dissolving enzyme (hyaluronidase) right where it was needed and avoid using large, guesswork doses.
The researchers suggested that using ultrasound during the injection itself could help to prevent blood-vessel injuries and enable faster, more precise treatment if blockages occur.
In the hands of an experienced, licensed professional using proper techniques, the risk of a vascular occlusion should be less than 1%, one plastic surgeon stated. (iStock)
“Ideally, ultrasound should be integrated into care in a way that supports timely decision-making — either as an immediate point-of-care tool in trained hands, or to confirm and optimize management once initial rescue therapy has begun,” Dr. Asif Pirani, a board-certified cosmetic plastic surgeon in Toronto, Canada, told Fox News Digital.
To minimize dangerous complications, Pirani — another outside expert not involved in the study — emphasized that injectable treatments should be performed by board-certified specialists with formal training in facial anatomy and complication protocols.
Study limitations
Some limitations of the study were noted, including its relatively small sample size (100 adults) and the fact that it has not yet been peer-reviewed.
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“Another limitation we noticed is that the Doppler exam is performed differently even among very experienced specialists,” the lead researcher told Fox News Digital. “This shows how important it is to create clear, standardized guidelines, so the exam can be done in a more consistent way.”
“Once a critical artery is occluded by filler or embolus, the damage may be irreversible.”
Also, all study participants experienced significant complications, which means the findings may not apply to those with milder cases or different filler types.
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There could also be some degree of geographic bias, as the research was conducted in Brazil, where training standards may differ from the U.S.
Future studies are needed to follow more patients over longer time periods and track their recovery after ultrasound-guided treatment, the study noted.
Health
Loneliness may be silently eroding your memory, new research reveals
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Feeling lonely may take a toll on older adults’ memory — but it may not speed up cognitive decline, according to a new study.
Researchers from Colombia, Spain and Sweden analyzed data from more than 10,000 adults ages 65 to 94 across 12 European countries and found those who reported higher levels of loneliness did worse on memory tests at the start of the study, according to research published this month in the journal Aging & Mental Health.
Over a seven-year period, however, memory decline occurred at a similar rate regardless of how lonely participants felt.
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“The finding that loneliness significantly impacted memory, but not the speed of decline in memory over time was a surprising outcome,” lead author Dr. Luis Carlos Venegas-Sanabria of the School of Medicine and Health Sciences at the Universidad del Rosario said in a statement.
Loneliness may be linked to memory performance in older adults, a new study suggests. (iStock)
“It suggests that loneliness may play a more prominent role in the initial state of memory than in its progressive decline,” Venegas-Sanabria said, adding that the findings highlight the importance of addressing loneliness as a factor in cognitive performance.
The findings add to debate about whether loneliness contributes to dementia risk. While loneliness and social isolation are often considered risk factors for cognitive decline, research results have been mixed.
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The study looked at data from the long-running Survey of Health, Ageing and Retirement in Europe (SHARE), which tracked 10,217 older adults between 2012 and 2019. Participants were asked to recall words immediately and after a delay to measure memory performance.
Social isolation and loneliness could play a surprising role in cognitive health among seniors. (iStock)
Loneliness was assessed using three questions about how often participants felt isolated, left out or lacking companionship.
About 8% of participants reported high levels of loneliness at the outset. That group tended to be older, more likely to be female and more likely to have conditions such as depression.
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Researchers found that those with higher loneliness had lower scores on both immediate and delayed memory tests at baseline. Still, all groups — regardless of loneliness level — experienced similar declines in memory over time.
The results suggest loneliness may not directly accelerate the progression of memory loss, though it remains linked to poorer cognitive performance overall.
Researchers look at a brain scan at the National Institutes of Health in Bethesda, Maryland. (Saul Loeb/AFP/Getty Images)
Experts warn, however, that the findings should not be interpreted to mean loneliness is harmless.
“The finding that lonely older adults start with worse memory but don’t decline faster is actually the most interesting part of the paper, and I think it’s easy to misread,” said Jordan Weiss, Ph.D., a scientific advisor and aging expert at Assisted Living Magazine and a professor at NYU Grossman School of Medicine.
“It likely means loneliness does its damage earlier in life, well before people show up in a study like this at 65-plus,” Weiss told Fox News Digital.
By older age, long-term social patterns may already be established, making it harder to detect when the effects of loneliness first took hold, an aging expert says. (iStock)
He suggested that by older age, long-term social patterns may already be established, making it harder to detect when the effects of loneliness first took hold.
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“By the time you’re measuring someone in their late 60s, decades of social connection patterns are already baked in,” he said.
Weiss, who was not involved in the research, added that loneliness may coincide with other health conditions, and noted that participants who felt more isolated also had higher rates of depression, high-blood pressure and diabetes. The link, he said, may reflect a cluster of health risks rather than a direct cause.
“While they can go hand-in-hand, it’s not clear that loneliness contributes to dementia,” a psychotherapist says. (iStock)
Amy Morin, a Florida-based psychotherapist and author, said the findings reflect a broader pattern in research on loneliness and brain health, and that the relationship may be more complex than it appears.
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“The evidence shows there’s a link between loneliness and cognitive decline but there’s no direct evidence of a cause and effect relationship,” she said. “So while they can go hand-in-hand, it’s not clear that loneliness contributes to dementia.”
Morin added that loneliness, which can fluctuate, may not be the root of the problem, but rather a symptom of other underlying mental or physical health issues.
Researchers suggested screening for loneliness be incorporated into routine cognitive assessments as one way to support healthy aging. (iStock)
She said staying socially and mentally engaged is crucial for overall brain health.
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“It’s important to be proactive about social activities,” Morin said. “Joining a book club, having coffee with a friend, or attending faith-based services can be a powerful way to maintain connections in older age.”
The researchers also suggested screening for loneliness be incorporated into routine cognitive assessments as one way to support healthy aging.
Fox News Digital reached out to the researchers for comment.
Health
Eat More To Lose Weight? She Dropped 55 Pounds by Having 5 Meals a Day
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Health
Intermittent fasting’s real benefit may come after you start eating again
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Research continues to uncover new details on how fasting may help extend life.
A new study published in the journal Nature Communications investigated how intermittent fasting can boost longevity in small worms often used in aging research.
Researchers from the University of Texas Southwestern Medical Center in Dallas compared worms that were fed normally to those that underwent a 24-hour fast in early adulthood and were then fed again, according to a press release.
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The scientists measured a variety of factors, including stored fat, gene activity related to fat metabolism and lifespan.
The results showed that the life-boosting benefit did not depend on the fasting itself but on the body’s behavior after eating again.
Experts say sustainability is key when choosing a long-term weight-loss strategy. (iStock)
Study lead Peter Douglas, associate professor of molecular biology and a member of the Hamon Center for Regenerative Science and Medicine at UT Southwestern, suggested that these discoveries “shift the focus toward a neglected side of the metabolic coin – the re-feeding phase.”
“Our data suggest that the health-promoting effects of intermittent fasting are not merely a product of the fast itself, but are dependent on how the metabolic machinery recalibrates during the subsequent transition back to a fed state,” he said.
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“Our findings bridge a gap between lipid metabolism and aging research,” he added. “By targeting aging, the single greatest risk factor for human disease, we move beyond treating isolated conditions toward a preventive model of medicine that enhances quality of life for all individuals.”
Lauri Wright, director of nutrition programs at the University of South Florida’s College of Public Health, called this a “high-quality” study that adds an “important nuance to how we think about fasting and longevity.”
Intermittent fasting typically involves limiting meals to an eight-hour daily window or fasting every other day. (iStock)
The benefits of the refeeding phase after fasting were “especially interesting,” Wright, who was not involved in the study, told Fox News Digital.
“The researchers showed that longevity was linked to the body’s ability to turn off fat breakdown after fasting, allowing cells to restore energy balance,” she reiterated.
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“From a scientific standpoint, that’s a meaningful shift because it suggests fasting is not just about burning fat, but about metabolic flexibility.”
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Fasting may support longevity through triggering metabolic switching, enhancing cellular repair and stress resistance and improving markers like insulin sensitivity, research shows.
Limitations and cautions
Although this study provides “important insight” on the power of refeeding, Wright noted that the findings should be approached with caution, as the study was done on worms and cannot always be translated to humans.
“Additionally, it explains how a process might work in a controlled lab condition rather than real-world eating behaviors,” she added as a limitation. “Finally, the study is short-term and doesn’t give us the long-term translation on lifespan outcomes.”
The review found intermittent fasting was barely more effective than doing nothing, according to the study authors. (iStock)
Wright cautioned that fasting is “not a magic solution for longevity, and how you eat overall matters more than when you eat.”
“I advise, first and foremost, to focus on diet quality, including a variety of fruits and vegetables, healthy fats and minimally processed foods,” she said.
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For those who are considering fasting, it’s better to stick with a moderate plan — like a 12- to 14-hour overnight fast — rather than going to extremes, Wright said. After fasting, she recommends focusing on well-balanced meals.
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Several groups of people should be cautioned against fasting, according to Wright, including those with diabetes who are on insulin or hypoglycemic medications, those who are pregnant or breastfeeding, anyone with a history of eating disorders and older adults at risk of malnutrition.
Anyone considering intermittent fasting should consult with a doctor before starting.
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