Health
Chicago nurse is finally free of COVID-19-related PTSD and depression after electrical brain tapping therapy
A Chicago nurse has been liberated from her own mind, thanks to a brain-tapping technology called deep TMS.
Gulden, who requested to omit her surname for privacy reasons, worked as a nurse for more than 40 years before COVID-19 rocked the hospital system and took a toll on her mental health.
The mother of four worked at Advocate South Suburban Hospital in Hazel Crest, Illinois, as an ICU and ER nurse.
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In an interview with Fox News Digital, Gulden described the “massive chaos” that the 2020 coronavirus pandemic brought to the hospital.
“No matter what we did, it was like a failure,” she said. “We were not prepared [for] the onslaught of patients.”
Housekeeper Tonia Harvey changes a bed in the Roseland Community Hospital intensive care unit after a COVID-19 patient passed away, April 17, 2020. (E. Jason Wambsgans/Chicago Tribune/Tribune News Service via Getty Images)
“The predictable outcome of coming in through the ER and leaving in a body bag was just devastating.”
Despite her many years of medical work, New York City-born Gulden admitted that she “could not cope with it.”
By Sept. 2020, she was a “different person,” she said.
“I was on autopilot. I lived at work and when I came home, I was not functioning … My organization and concentration skills were gone.”
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“It was very, very unlike me, because I’m a single mom. I’ve raised four kids all by myself … but I started to notice that I could not let go of what had transpired during the day.”
Gulden told her primary care provider about her symptoms, including “horrible nightmares” that prevented her from sleeping and constant “weeping” that came “from her soul.”
Gulden, pictured here, said that working in a hospital during the coronavirus pandemic turned her into a “different person.” (Melanie Eilers)
In the span of two years, the doctor prescribed Gulden eight different medications for sleep, PTSD and major depressive disorder, along with cognitive behavior therapy — but nothing worked.
Even after the pandemic began to slow down, the nurse described how she hit a “spiral” when she realized COVID-19 created a “chain reaction.”
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“[There] was a 51-year-old who had bilateral tumors and needed a mastectomy,” she shared. “She’d gone through all her chemo and radiation, and she was ready for her mastectomy, but she had to wait like 11 months.”
Added Gulden, “By the time she came back, her tumors had grown back, and that’s when I was like, This is never going to be over.”
Gulden mentioned that screenings for major health complications were down at least 84% during the pandemic, feeding into a “ripple” of patients who received care too late.
Tamara Jones gives antibiotics to James Davis as he recovers from COVID-19 in the intensive care unit at Roseland Community Hospital on Dec. 16, 2020, in Chicago, Illinois. (Scott Olson/Getty Images)
The nurse said through tears that she decided to leave the hospital and retire, since she “just couldn’t function there.”
After leaving, she fell into a “hibernation state” of sleeping 16 to 18 hours a day.
“The only reason I got up was to go to the bathroom,” she said. “And I’m embarrassed to say I would go weeks without showering.”
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“I lost 54 pounds — I got to the point where I couldn’t eat, because everything in the refrigerator reminded me of what was on patients’ trays.”
Gulden’s “incredibly vivid, horrible nightmares” continued along with other symptoms, including the inability to stay awake. She called it a “complete shutdown.”
Gulden received deep TMS treatment at Relief Mental Health in Orland Park, Illinois. (Melanie Eilers)
After Gulden spent three years in “hibernation,” a friend introduced her to a new type of mental health treatment called deep TMS (transcranial magnetic stimulation) — a magnetized tapping of the brain used to treat various disorders and diseases.
Gulden agreed to visit Dr. Teresa Poprawski, the chief medical officer of Relief Mental Health in Orland Park, Illinois, who helped “put the threads together” on what was triggering her PTSD and other symptoms.
What is deep TMS?
Dr. Aaron Tendler, a psychiatrist and chief medical officer of BrainsWay, a brain disorder treatment company, discussed how the therapy works in an interview with Fox News Digital.
Tendler is based in West Palm Beach, Florida and was not involved in Gulden’s care. He said the brain is primarily an “electrochemical organ” that sends messages to different parts of the body.
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Most symptoms, including depression and anxiety, are controlled by changes in the brain, Tendler said, which can be treated electrically.
Deep TMS is a more “targeted” approach than electroshock therapy, he told Fox News Digital.
Gulden described the sensation of deep TMS as “tapping on specific parts of the brain.” (iStock; BrainsWay)
“Transcranial magnetic stimulation uses the principle of electromagnetic induction, where magnetic pulses induce an electrical current inside of neurons,” he said.
“Essentially, we are changing the electrical activity in a group of neurons in an area of the brain.”
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These magnetic pulses only stimulate a specific area of the brain for “a brief period of time,” he said, with treatments lasting anywhere from six to 20 minutes. Patients undergo treatments for a series of days, depending on what’s necessary.
Tendler described the therapy as a “learning experience” that changes “the state of the brain” through repetitive treatment.
Deep TMS interrupts activity in the brain that is creating unwanted patterns, an expert said. (BrainsWay)
Gulden received deep TMS treatments for five days a week, for six to eight weeks. She described the sensation as “tapping on specific parts of the brain.”
After three weeks, she reported a noticeable difference in her cognitive state.
“I realized, ‘Oh my gosh, it’s been three years since I’ve heard the birds,’” she said. “I see life again. I see my flowers. Before, I couldn’t even look at the flowers because they just reminded me of funerals.”
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Gulden described her quality of life as “just so much better” since receiving treatment.
She still attends cognitive behavioral therapy sessions to hone her coping skills, she said.
“And if I need deep TMS again, I will be back there in a heartbeat,” she added.
Deep TMS is covered by “every insurer” across the country, according to one expert. (BrainsWay)
‘Very useful tool’
Gulden’s goal is to teach others to not feel ashamed about seeking help for their mental health struggles.
“I want people to know that there are interventions,” she said.
“The meds did not work for me. Had I not had this treatment today, I don’t know where I’d be.”
Although deep TMS technology was developed in the 1980s, the first treatment application for depression was FDA-cleared in 2009. (BrainsWay)
Most patients experience a 40% to 50% improvement after four weeks of treatment, according to Tendler.
After completing a typical course of 36 treatments, patients have shown 75% to 80% improvement, he said.
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Deep TMS is “not a cure,” Tendler said — but many patients are able to regain normal function for months or years at a time.
The electrical therapy doesn’t have the potential side effects that antidepressants and other treatments can cause, Tendler said, noting that the brain manipulation is “temporary.”
“Had I not had this treatment today, I don’t know where I’d be,” Gulden said. (Melanie Eilers)
“I know this might sound like a disadvantage, but it is also an advantage,” he said. “We don’t do anything to the person’s brain that’s permanent. We’re changing the state of the brain temporarily.”
He added, “Generally, we get you out of the state that you were in … and then nature takes its course.”
Deep TMS can also be paired with other medications, such as antidepressants, Tendler added.
Fox News medical contributor Dr. Marc Siegel cautioned that deep TMS could potentially cause some cognitive and behavioral changes, but called it a “very useful tool” overall. (Dr. Marc Siegel)
Fox News medical contributor Dr. Marc Siegel cautioned that deep TMS could potentially cause some cognitive and behavioral changes, but called it a “very useful tool” overall.
He told Fox News Digital that deep TMS is also “very useful for movement disorders like Parkinson’s, with a high rate of success.”
“We’re changing the state of the brain temporarily.”
Siegel cautioned that deep TMS could potentially cause some cognitive and behavioral changes, but called it a “very useful tool” overall.
“[Deep TMS is] still being investigated for various purposes to interrupt aberrant nerve conduction,” he said.
For other medical professionals suffering from mental health issues, Gulden stressed the importance of having a “healthy health care team,” especially following the pandemic.
“I don’t care how tough you think you are,” she said. “You need to know what the signs are, and you need to know what treatments are available.”
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The Murdoch Children’s Research Institute (MCRI) in Australia will receive a $5 million federal grant to launch a pioneering research team for children’s health.
The grant was announced at MCRI’s 40th anniversary gala in Melbourne on Saturday night.
“For 40 years, MCRI has been a global leader in children’s health research,” Prime Minister Anthony Albanese told guests at the gala, which was attended by 300 of Australia’s most esteemed medical experts, political leaders, philanthropists and sports luminaries.
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“My government is proud to partner with MCRI, so our world-leading researchers have the best opportunities to support healthier childhoods for Australians now and into the future.”
The $5 million will directly support medical research aimed at preventing numerous childhood conditions, including obesity, heart disease, mental health issues and disabilities.
Australian Prime Minister Anthony Albanese speaks at the MCRI gala. (Penny Stephens/Murdoch Children’s Research Institute)
Also announced at the gala, a lead donation from Sarah and Lachlan Murdoch will launch the Horizon Fund — a permanent endowment for MCRI aimed at funding long-term children’s health research and future medical breakthroughs.
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The goal is for the fund to raise between $50 million and $100 million in its first year and to reach $200 million within five years.
The fund is designed to back researchers’ immediate priorities while safeguarding long-term capital for future medical breakthroughs in children’s health.
Pictured above, Sarah Murdoch (MCRI co-chair); Jodie Haydon (wife of Prime Minister Albanese); Australian Prime Minister Anthony Albanese; Kathryn North (MCRI director); and Patrick Houlihan (MCRI chair). (Christopher Hopkins/Murdoch Children’s Research Institute)
In 2020, the Murdochs donated $5 million to establish a perpetual fellowship supporting leading researchers in fields including stem cell technology and genomic precision medicine.
Co-founded in 1986 by philanthropist and child health advocate Dame Elisabeth Murdoch and pediatrician and genetics pioneer Professor David Danks, MCRI comprises 1,800 scientists, researchers and clinicians.
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“Dame Elisabeth’s leadership, along with her values, shaped both the direction and the ethos of the Institute we were to become – for all children to live a healthy and fulfilled life,” said Sarah Murdoch, who is Dame Elisabeth Murdoch’s granddaughter-in-law and MCRI’s global ambassador and board co-chair.
Sarah Murdoch (MCRI co-chair) is pictured with Kathryn North (MCRI director) at the Murdoch Children’s Research Institute 40th Anniversary Gala at the State Library Melbourne. (Penny Stephens/Murdoch Children’s Research Institute)
“With the generosity of a remarkable group of founding donors alongside the Murdoch family – Sir Jack Brockhoff, the Miller family, and The Scobie and Claire Mackinnon Trust – the foundations were laid for an Institute designed to bring our brightest minds, to serve all children, not only in that moment, but for generations to come,” Ms. Murdoch added.
“I see what is possible when foresight, science, commitment, collaboration and heartfelt generosity come together,” she emphasized.
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“Because behind every breakthrough is a child — a family desperate for answers. A future changed because of the commitment by so many.”
MCRI Director Kathryn North expressed appreciation at the gala to the prime minister for the $5 million grant.
“From the beginning, MCRI has been guided by a simple but powerful purpose: to give all children the opportunity to live a healthy and fulfilled life,” said the MCRI director. (MCRI)
“From the beginning, MCRI has been guided by a simple but powerful purpose: to give all children the opportunity to live a healthy and fulfilled life,” North said.
“It reflects a belief that good health is the foundation for a full life, and that opportunity should never be limited by circumstance.”
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Professor North mentioned the Institute’s focus on developing therapies for previously incurable diseases.
“We are harnessing the power of human stem cell technologies to grow heart patches, functional mini kidneys, blood and immune cells … to better understand disease, and to develop regenerative therapies using a patient’s own stem cells to replace organ transplants and the risk of rejection,” she said.
The Institute’s next challenge is to address chronic conditions like asthma, obesity, allergies and mental health conditions that can persist for decades. (iStock)
The Institute’s next challenge, North said, is to address chronic conditions like asthma, obesity, allergies and mental health conditions that can persist for decades.
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“These are big problems that will require significant and ongoing support,” she said. “Through our work globally, we are helping communities raise their expectations to both deliver and receive the sort of healthcare we take for granted.”
“Our ambition now is to translate these partnerships into population-scale solutions that improve the lives of millions of children worldwide,” North added. “This is not simply the next chapter for MCRI – it is the work of building the future of children’s health.”
FDA fast-tracks pancreatic cancer drug daraxonrasib
Family and emergency medicine physician Dr. Janette Nesheiwat discusses how artificial intelligence could help detect pancreatic cancer earlier and the FDA fast-tracking the drug daraxonrasib on ‘Fox Report.’
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A new drug for pancreatic cancer is showing promise in early testing.
Daraxonrasib is a daily pill designed to block cancer signals linked to the RAS gene. It has now finished an early-stage clinical trial — the first time it was tested in people — to evaluate both its safety and effectiveness.
The clinical trial, led by the Dana-Farber Cancer Institute and published in The New England Journal of Medicine, tested the drug in 168 patients with advanced pancreatic cancer whose tumors had mutations in the RAS gene. All study participants had previously received at least one chemotherapy treatment.
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The drug is designed to block multiple active cancer signals that help tumor cells grow. This is especially important because more than 90% of pancreatic cancers carry these harmful mutations, researchers said.
Existing and older drugs that target RAS mutations only work on certain types that are uncommon in pancreatic cancer, such as KRAS mutations.
Daraxonrasib is a daily pill designed to block cancer signals linked to the RAS gene. It has now finished an early-stage clinical trial to evaluate its safety and effectiveness. (iStock)
At the 300-milligram dose — the amount that will be used in larger phase 3 trials — about 30% of patients saw a positive response, researchers noted. Overall, about 90% of patients had their cancer either shrink or stop getting worse.
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There were some side effects reported — most commonly rash, mouth inflammation, nausea and diarrhea.
Lead investigator Dr. Brian Wolpin, director of the Hale Family Center for Pancreatic Cancer Research at Dana-Farber, commented in a press release statement that this development could change the future of cancer care.
About 90% of patients treated with the drug experienced disease control, meaning their cancer was reduced or stabilized. (iStock)
“If supported by data from future clinical trials, daraxonrasib would be a targeted therapy relevant to nearly all patients with advanced pancreatic cancer,” he said.
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“This trial provides the first published data showing the safety and broad activity of a RAS(ON) multi-selective inhibitor in pancreatic cancer,” Wolpin went on. “If it proves effective in larger clinical trials, it would signify a substantial shift in how this disease is treated.”
In an interview with Fox News Digital, the researcher claimed that daraxonrasib represents “one of the most promising therapy advances we’ve seen in pancreatic cancer.”
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This is especially significant since pancreatic cancer has had “very few effective therapies” in the past, Wolpin noted.
“The study also showed disease control in approximately 90% of patients with metastatic pancreatic cancer, which is extremely exciting,” he added.
The study does not prove daraxonrasib is superior to standard treatment of chemotherapy, researchers noted. (iStock)
Wolpin noted that while side effects were common, most patients were able to tolerate treatment with “supportive care measures, and very few patients needed to stop therapy due to side effects.”
As this was a phase 1/2 study, it does not “definitively prove” the superiority of daraxonrasib compared to chemotherapy, Wolpin added.
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“The study did not include a randomized control arm that directly compared daraxonrasib with chemotherapy,” he said. “That being said, the results for daraxonrasib looked substantially better than what we have seen in prior clinical trials of chemotherapy in patients with previously treated metastatic pancreatic cancer.”
It also remains unclear how the drug may perform earlier in the disease, as the trial included patients who had already received prior treatments.
“Additional research is needed to determine how best to sequence or combine therapies to provide the most durable responses and cures,” the lead investigaror sid. (iStock)
For patients and families affected by pancreatic cancer, Wolpin noted that daraxonrasib signals “real momentum” toward effective treatments, but it is still investigational and is not a cure.
“Pancreatic cancer remains a challenging disease, and additional research is needed to determine how best to sequence or combine therapies to provide the most durable responses and cures,” he said.
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Brian Slomovitz, director of gynecologic oncology and co-chair of the Cancer Research Committee at Mount Sinai Medical Center in Miami Beach, applauded this development in a separate interview with Fox News Digital.
“We are anxiously awaiting the upcoming plenary presentation of RASolute 302 at the ASCO meeting later this month,” said the expert, who was not involved in the study. “Greater than 90% of pancreatic cancers have activation of kRAS, which is a major factor in the development and progression of these cancers.”
“Doubling the survival time in pretreated patients is unprecedented.”
“If the full dataset results that will be reported later this month confirm what was earlier released, I believe this will be one of the most important breakthroughs in all solid tumors,” Slomovitz went on. “Doubling the survival time in pretreated patients is unprecedented.”
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The doctor added that the “magnitude of benefit” could “reshape the treatment landscape” and “establish a new standard of care.”
“We will need to evaluate the full dataset for efficacy and safety,” Slomovitz added. “I am more than cautiously optimistic, and I am truly excited for our patients and their families that suffer from this dreadful disease.”
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People who regularly visit museums or participate in creative activities may be aging more slowly on a biological level, according to a new study from the United Kingdom.
Researchers from University College London analyzed data from more than 3,500 adults and found that people who frequently engaged in arts and cultural activities showed signs of slower biological aging in several DNA-based measurements.
The findings were published in the journal Innovation in Aging.
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The study examined activities including painting, photography, dancing, singing, visiting museums and attending cultural events or historic sites.
People who frequently visit museums or engage in artistic activities may experience slower biological aging. (iStock)
Researchers compared participation in those activities with “epigenetic clocks,” scientific tools that examine chemical changes in DNA over time.
Adults who participated more often, and in a wider variety of activities, tended to show slower aging scores compared to people who rarely engaged in arts or cultural experiences.
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The association appeared even stronger among adults over age 40.
Researchers also noted that the effect sizes were comparable to those linked to physical activity, one of the most widely studied behaviors associated with healthy aging.
The study found that adults who engaged more often in arts and cultural activities showed slower biological aging. (iStock)
Jessica Mack, a health and wellness expert and founder of The Functional Consulting Group who was not involved in the study, said the findings reflect a growing understanding that health is influenced by more than exercise and nutrition alone.
“Arts and cultural engagement may be associated with slower epigenetic aging, with effects comparable in some measures to physical activity,” Mack told Fox News Digital.
She said activities such as visiting museums and engaging with music or art may help reduce stress, improve emotional regulation and increase social connection.
Experts say these activities may reduce stress, improve emotional regulation, and strengthen social connections. (iStock)
“These are not ‘extra’ lifestyle activities,” Mack said. “They may be deeply connected to how the body manages inflammation, stress hormones, mood and overall resilience.”
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Mack added that people experiencing stress, social isolation, retirement or caregiving responsibilities may especially benefit from meaningful cultural engagement.
Experts cautioned, however, that the study does not prove arts engagement directly slows aging.
“This is an observational study, not an experiment,” Professor Steve Horvath of UCLA, a longevity researcher and pioneer in epigenetic aging research who was not involved in the study, told Fox News Digital.
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“So when researchers find that the people who go to museums have younger epigenetic age, we cannot tell whether the museum visits slowed their aging, or whether their slower aging is what allowed them to keep visiting museums,” he said.
While the findings suggest a link, experts caution that the study cannot prove arts and cultural activities directly slow aging. (iStock)
Horvath said both explanations may be true to some degree, though he described the research as “methodologically careful” and worthy of further study.
The findings remained consistent even after accounting for factors such as smoking, income, body weight and other lifestyle habits.
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He added that regardless of whether arts engagement is directly slowing biological aging, staying socially and mentally active is still associated with healthier aging overall.
“The prescription is the same,” he said. “Keep going.”
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