Health
AI health care platform predicts diabetes with high accuracy but ‘won’t replace patient care’
With 37.3 million individuals within the U.S. residing with diabetes — 8.5 million of whom are undiagnosed, per the Facilities for Illness Management and Prevention — the illness is likely one of the deadliest and most costly within the nation.
Cedar Gate Applied sciences, a medical tech improvement firm in Greenwich, Connecticut, introduced on Tuesday a brand new AI-based resolution that goals to scale back the burden of diabetes for each sufferers and suppliers.
In a latest research, Cedar Gate used its resolution, Cedar Gate Analytics, to guage the information of greater than 1.2 million sufferers in its database inside a 12-month interval.
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The outcomes confirmed that 80% of sufferers with no recognized diabetes who had been recognized by the mannequin had been confirmed to develop the illness within the following yr, the corporate stated.
‘Making use of know-how to industrial use circumstances’
The corporate stated in a press launch that Cedar Gate Analytics is the “first commercially accessible and deployed value-based platform with this degree of accuracy.”
Rajiv Mahale, chief product and enterprise improvement officer at Cedar Gate, instructed Fox Information Digital in an interview that this implies “we are able to confidently determine people who find themselves at the next danger of creating or being identified with diabetes sooner or later.”
The AI mannequin (not pictured) confirmed that 80% of sufferers with no recognized diabetes who had been recognized by the mannequin had been confirmed to develop the illness within the following yr. (iStock)
Cedar Gate Analytics isn’t the one AI-based mannequin that goals to detect diabetes danger, however the firm says it’s “the primary of its type at this degree.”
Mahale stated, “Whereas there have been many university-based analysis research displaying the aptitude of AI-related diabetes prediction fashions, we’re making use of our know-how to industrial use circumstances, placing superior analytics instruments within the palms of enterprise customers to unravel real-world issues.”
“We don’t count on AI to switch affected person care.”
He added, “Right this moment, we now have the know-how to curb the trajectory of diabetes deeply and meaningfully, controlling value and enhancing well being outcomes at scale.”
‘Accountable to sufferers’
Cedar Gate’s AI platform is meant to be used by medical professionals, defined David Snow, chairman and CEO of Cedar Gate Applied sciences.
The objective is to offer medical doctors the data they should determine the sufferers who’re vulnerable to creating diabetes.
Cedar Gate Analytics (not pictured) isn’t the one AI-based mannequin that goals to detect diabetes danger, however the firm says it is “the primary of its type at this degree.” (iStock)
“On the finish of the day, clinicians are accountable to sufferers,” Snow stated in an interview with Fox Information Digital.
“The info tells the medical doctors the sufferers will develop diabetes in the event that they don’t intervene, enabling them to keep away from the acute onset of an issue.”
Snow stated that Cedar Gate Analytics displays the corporate’s broader objective of shifting to a brand new well being care mannequin — one centered on “value-based care” moderately than “fee-for-service.”
Greater than 37 million individuals within the U.S. have diabetes — 8.5 million of whom are undiagnosed.
“With the fee-for-service mannequin, suppliers are rewarded for ready for individuals to get sick,” he defined.
“With value-based care, they’re rewarded for protecting individuals effectively.”
‘Creating that means’
Cedar Gate’s AI mannequin relies on a number of years of medical claims knowledge. It makes use of machine studying networks to foretell the chance of many persistent circumstances, together with diabetes.
“These sorts of insights should not new — however this degree of accuracy and predictability is thrilling,” Snow stated.
“At present, there isn’t a resolution recognized to prime business analysts that is ready to attain 80%+ accuracy at true, substantial scale.”
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Mahale defined that they’re not merely feeding uncooked knowledge into an algorithm.
“We now have knowledge scientists and medical people creating that means from the information earlier than it goes right into a mannequin, defining the affected person’s journey and key occasions,” stated Mahale.
“Our instruments have the potential to succeed in a far larger share of the inhabitants who’re vulnerable to contracting a severe persistent illness.”
“Our instruments have the potential to succeed in a far larger share of the inhabitants who’re vulnerable to contracting severe persistent illness,” stated Cedar Gate’s chief product officer. (iStock)
The researchers predict that by pinpointing diabetes danger earlier and enhancing affected person outcomes, the corporate may probably assist save hundreds of thousands of {dollars}’ value of well being care expenditures.
For every individual with diabetes, the annual value totals $9,601 per yr, in keeping with the American Diabetes Affiliation.
Using synthetic intelligence and machine studying in well being care isn’t new — however it’s quickly rising because the know-how opens up new methods of enhancing affected person care and growing suppliers’ effectivity.
As of October 2022, the Meals & Drug Administration (FDA) listed greater than 500 AI/ML-enabled medical gadgets which are accessible in america.
‘You must have a look at the information’
Dr. Harvey Castro, a Dallas, Texas-based board-certified emergency medication doctor and nationwide speaker on synthetic intelligence in well being care, believes AI platforms are a wonderful device for preventative medication.
“The extra we learn about a illness state, the extra doubtless we’re to do our greatest to remain wholesome by altering our habits,” he instructed Fox Information Digital.
“I see this being the way forward for preventive medication.”
Castro cautions, nevertheless, that most of these fashions are likely to predict solely what they’ve studied — so the data can probably be considerably biased towards a sure area or group of individuals.
With 37.3 million individuals within the U.S. residing with diabetes — 8.5 million of whom are undiagnosed — the illness is likely one of the deadliest and most costly within the nation. (iStock)
“Due to this fact, you need to have a look at the information and see if it represents the whole U.S. inhabitants; if not, this info may not apply to you,” he stated.
“For instance, somebody in West Africa may not have the identical danger calculator as somebody from California or New York Metropolis.”
Wanting forward, the Cedar Gate staff plans to launch comparable AI fashions targeted on detecting different persistent ailments, together with coronary artery illness, congestive coronary heart failure and COPD.
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Sooner or later, the group plans to use the know-how to advanced ailments like a number of sclerosis, Parkinson’s and Alzheimer’s.
“We don’t count on AI to switch affected person care,” Snow stated.
“It simply provides us the flexibility to raised inform those that are chargeable for delivering care so that they’re more practical with their sufferers.”
He added, “With such an unlimited quantity of knowledge in well being care, highly effective analytics are a necessity.”
The U.S. Food and Drug Administration (FDA) has recommended that COVID vaccine manufacturers update their formulas for fall doses, in an attempt to target the KP.2 strain of the JN.1 variant.
The Thursday announcement came just a week after the agency’s Vaccines and Related Biological Products Advisory Committee (VRBPAC) voted to recommend a “monovalent JN.1-lineage vaccine” at its June 5 meeting.
As of the end of March 2024, the KP.2 variant was responsible for just 4% of infections in the U.S., according to the COVID Data Tracker from the Centers for Disease Control and Prevention (CDC).
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Meanwhile, over 50% of infections at that time were attributed to its parental strain, JN.1.
Just a few weeks later, KP.2 is now the cause of around 28% of infections, while the JN.1 variants have largely dropped in prevalence, the tracker shows.
The U.S. Food and Drug Administration has recommended that COVID vaccine manufacturers update their formulas for fall doses, in an attempt to target the KP.2 strain of the JN.1 variant. (iStock)
Dr. Marc Siegel, clinical professor of medicine at NYU Langone Medical Center and a Fox News medical contributor, recently spoke with Dr. Peter Marks, director of the Center for Biologics Evaluation and Research (CBER) at the Food and Drug Administration, about the new vaccine formulations.
“It makes sense to target the KP.2 strain because it is becoming the predominant strain — it is surging in California and will spread across the country,” Siegel told Fox News Digital.
KP.2 is now the cause of around 28% of infections, while the JN.1 variants have largely dropped in prevalence, CDC Tracker data shows. (iStock)
The KP.2 strain is “highly immunoevasive,” the doctor warned — which means that immunity from previous variants and subvariants don’t offer much protection.
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“On the other hand, the vaccine will cause a production of immune cells and antibodies that will continue to protect you against previous variants and subvariants,” Siegel added.
The updated vaccine is especially important for high-risk groups, those who have chronic illnesses, the elderly and anyone who comes in contact with them, according to doctors. (iStock)
It is especially important for high-risk groups, those who have chronic illnesses, the elderly and anyone who comes in contact with them, according to the doctor.
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In a statement to Fox News Digital, vaccine maker Novavax — which makes protein-based vaccines — said the company “just filed” its application for a JN.1 COVID vaccine.
A vial of the Phase 3 Novavax coronavirus vaccine is seen ready for use in the trial at St. George’s University hospital in London, on Oct. 7, 2020. (AP Photo/Alastair Grant, File)
“Novavax’s updated JN.1 COVID-19 vaccine is active against current circulating strains, including KP.2 and KP.3,” the company said in a press release.
“The submission is in line with guidance from the U.S. FDA, European Medicines Agency (EMA) and the World Health Organization (WHO) to target the JN.1 lineage this fall.”
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Fox News Digital reached out to Pfizer and Moderna — both of which produce mRNA-based vaccines — requesting comment on their plans for fall formulations.
Heart disease has been the world’s No. 1 killer for over a century, and experts predict that it will become even more prevalent in the coming decades.
A report this month from the American Heart Association (AHA) predicts that at least six in 10 U.S. adults could experience cardiovascular disease within the next 30 years.
The rate of hypertension (high blood pressure) — which is one of the key risk factors for heart disease — is expected to increase from 51.2% in 2020 to 61.0% in 2050.
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Diabetes, another major risk factor, is also expected to rise (16.3% to 26.8%), along with obesity (43.1% to 60.6%), according to the study, which was published in the AHA journal Circulation.
As a result, total cardiovascular disease is predicted to rise from 11.3% to 15.0% between 2020 and 2050.
Heart disease has been the world’s No. 1 killer for over a century, and experts predict that it will become even more prevalent in the coming decades. (iStock)
“The landscape of cardiovascular disease in the U.S. is seeing the arrival of a near-perfect storm,” Dr. Dhruv S. Kazi, vice chair of the advisory writing group and a Boston cardiologist, said in a press release.
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“The last decade has seen a surge of cardiovascular risk factors, such as uncontrolled high blood pressure, diabetes and obesity, each of which raises the risks of developing heart disease and stroke,” he continued.
“It is not surprising that an enormous increase in cardiovascular risk factors and diseases will produce a substantial economic burden.”
As a result of the risk factors identified in the study, total cardiovascular disease is predicted to rise from 11.3% to 15.0% between 2020 and 2050. (iStock)
On a positive note, the researchers determined that hypercholesterolemia (high levels of LDL, or “bad cholesterol”), will decline (45.8% to 24.0%).
They also predicted that diet, exercise and smoking habits will improve, although sleep quality is expected to worsen.
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The researchers analyzed data from the 2015 to March 2020 National Health and Nutrition Examination Survey and the 2015 to 2019 Medical Expenditure Panel Survey.
“We projected through 2050, overall and by age and race and ethnicity, accounting for changes in disease prevalence and demographics,” they wrote.
“[The] most adverse trends are projected to be worse among people identifying as American Indian/Alaska Native or multiracial, Black or Hispanic.”
Life’s Essential 8 consists of the following eight lifestyle behaviors for optimal heart health, according to the American Heart Association. (iStock/American Heart Association)
The study looked for trends in cardiovascular risk factors based on adverse levels of Life’s Essential 8 and clinical cardiovascular disease and stroke.
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Life’s Essential 8 consists of the following eight lifestyle behaviors for optimal heart health, according to the AHA:
- Following a healthy sleep schedule
- Not smoking
- Getting regular physical activity
- Adhering to a healthy diet
- Maintaining a healthy body weight
- Maintaining healthy blood glucose levels
- Maintaining healthy cholesterol levels
- Maintaining healthy blood pressure
Overall, the report predicts that clinical cardiovascular disease (affecting the heart or blood vessels) will affect 45 million adults by 2050, and clinical cardiovascular disease (including hypertension) will affect more than 184 million adults.
Overall, the report predicts that clinical cardiovascular disease (affecting the heart or blood vessels) will affect 45 million adults by 2050, and clinical cardiovascular disease (including hypertension) will affect more than 184 million adults. (iStock)
“The prevalence of many cardiovascular risk factors and most established diseases will increase over the next 30 years,” the researchers stated.
Renato Apolito, M.D., the medical director of the Cardiac Catheterization Laboratory at Hackensack Meridian Jersey Shore University Medical Center, was not involved in the AHA study but shared his insights on the findings.
“We are all under a lot of pressure and stress to work more to make ends meet.”
One of the key factors is the projected increase in obesity in the coming decades, Apolito said in an interview with Fox News Digital.
“Obesity is very commonly associated as a driver of hypertension, diabetes, sleep apnea and hypertriglyceridemia,” he said.
Some of the greater causes of obesity are lack of exercise and a heavy reliance on processed and fast food, he noted.
Some of the greater causes of obesity are lack of exercise and a heavy reliance on processed and fast food, a cardiologist said. (iStock)
“I suspect that as our standard of living goes up, our reliance on processed and pre-prepared food — in addition to lack of exercise and lack of sleep from our hectic work lives — will drive up obesity as the common denominator leading to all the other risk factors mentioned,” Apolito predicted.
“All of those factors put together would lead to an increase in coronary artery disease, heart failure and stroke.”
Reducing the risk
“Clinical and public health interventions are needed to effectively manage, stem and even reverse these adverse trends,” the researchers advised.
Apolito agreed that change is needed.
“We are all under a lot of pressure and stress to work more to make ends meet,” he said.
“This typically leads to the bad lifestyle habits mentioned above.”
The doctor recommends starting small, setting aside just 10 to 20 minutes per day to do some form of exercise and to make conscious decisions to avoid processed and fast foods.
A cardiologist recommends starting small, setting aside just 10 to 20 minutes per day to do some form of exercise and to make conscious decisions to avoid processed and fast foods. (iStock)
“You would maintain a healthier weight, which would mitigate your risk of hypertension, diabetes, sleep apnea, dyslipidemia and, ultimately, cardiovascular disease,” he said.
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Apolito also pointed out that the study is speculative, using predictive models on data from the past and present to predict the future — “which is never easy to do.”
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“Hopefully, with increased public education, we can turn the tide and improve overall health in the coming decades by making healthy choices in lifestyle,” he added.
Health
Mushroom-infused 'microdosing' chocolate bars are sending people to the hospital, prompting investigation: FDA
The Food and Drug Administration (FDA) is warning consumers about a mushroom-infused chocolate bar that has reportedly sent some people to the hospital.
The FDA released an advisory message about Diamond Shruumz “microdosing” chocolate bars on June 7. The chocolate bars contain a “proprietary nootropics blend” that is said to give a “relaxed euphoric experience without psilocybin,” according to its website.
“The FDA and CDC, in collaboration with America’s Poison Centers and state and local partners, are investigating a series of illnesses associated with eating Diamond Shruumz-brand Microdosing Chocolate Bars,” the FDA’s website reads.
“Do not eat, sell, or serve Diamond Shruumz-Brand Microdosing Chocolate Bars,” the site warns. “FDA’s investigation is ongoing.”
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The FDA is warning consumers against Diamond Shruumz chocolate bars. (FDA | iStock)
“Microdosing” is a practice where one takes a very small amount of psychedelic drugs with the intent of increasing productivity, inspiring creativity and boosting mood. According to Diamond Shruumz’s website, the brand said its products help achieve “a subtle, sumptuous experience and a more creative state of mind.”
“We’re talkin’ confections with a kick,” the brand said. “So if you like mushroom chocolate bars and want to mingle with some microdosing, check us out. We just might change how you see the world.”
But government officials warn that the products have caused seizures in some consumers and vomiting in others.
“People who became ill after eating Diamond Shruumz-brand Microdosing Chocolate Bars reported a variety of severe symptoms including seizures, central nervous system depression (loss of consciousness, confusion, sleepiness), agitation, abnormal heart rates, hyper/hypotension, nausea, and vomiting,” the FDA reported.
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Six people reportedly experienced such severe reactions that they sought medical care.
At least eight people have suffered a variety of medical symptoms from the chocolates, including nausea. (iStock)
“All eight people have reported seeking medical care; six have been hospitalized,” the FDA’s press release said. “No deaths have been reported.”
Diamond Shruumz says on its website that its products are not necessarily psychedelic. Although the chocolate is marketed as promising a psilocybin-like experience, there is no psilocybin in it.
“There is no presence of psilocybin, amanita or any scheduled drugs, ensuring a safe and enjoyable experience,” the website claims. “Rest assured, our treats are not only free from psychedelic substances but our carefully crafted ingredients still offer an experience.”
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“This allows you to indulge in a uniquely crafted blend designed for your pleasure and peace of mind.”
Officials warn consumers to keep the products out of the reach of minors, as kids and teens may be tempted to eat the chocolate bars.
The chocolate bars are marketed as products that boost mood and creativity. (iStock)
“This product may appeal to children and teenagers as it is marketed as a candy,” the FDA advises. “Parents and caregivers should consider discussing the information in this advisory with their children and take extra care to avoid this product being consumed by younger people.”
The FDA and CDC are actively investigating the products.
Fox News Digital reached out to Diamond Shruumz for comment, but did not hear back.
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