Health
ADHD in males versus females: What you must know about the differences in symptoms and treatments
Attention-deficit/hyperactivity disorder (ADHD) may be common, but it’s also sometimes hard to spot.
ADHD is usually first diagnosed in childhood and is one of the most common neurodevelopmental disorders in children, according to the Centers for Disease Control and Prevention (CDC).
Symptoms of ADHD in kids can include trouble paying attention, difficulty controlling impulsive behaviors and displaying periods of hyperactivity.
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But how these symptoms show up in boys versus girls, and eventually in men versus women, can make a big difference in diagnosis.
Sabrina Nasta, a licensed mental health counselor in Orange Park, Florida, told Fox News Digital that ADHD can show up in three different ways: through inattention, hyperactivity and a combination of the two.
ADHD in males compared to females can means significantly different symptoms, experts say. (iStock)
In women, ADHD most commonly manifests as inattention, which includes an inability to pay attention, distractibility and lack of compliance, according to Nasta.
In men, ADHD occurs in a hyperactive way, causing issues with sitting still or wanting to be constantly “doing something,” said the expert.
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McCall Letterle, head of U.S. commercial operations for ADHD assessment company Qbtech, also commented on these differences in a conversation with Fox News Digital.
Athough many of the symptoms, including hyperactivity, inattention and impulsivity, are the same, it’s how the symptoms “manifest themselves” that causes a variation between males and females, the Atlanta-based expert noted.
Young girls with ADHD may sit still in the classroom, but they’re “not paying attention,” an expert said. (iStock)
A struggle with discipline seems to be a commonality of ADHD in men and women based on their lifestyle and age, Nasta added.
In young boys, for example, ADHD shows up as “unnecessary” hyperactive energy; they “don’t have the capacity to not do anything,” the expert said.
In girls, the same inattentiveness may arise, but it’s most likely internalized.
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“They may be sitting in the classroom, they may be sitting still, but they’re not paying attention,” Nasta said.
“It’s tough because for a girl, it looks like they’re rebelling or being disobedient, [but] for a boy, [it seems that] they’re just being ridiculous and hyper.”
Underdiagnosis in women
The differences in ADHD presentation have led to a “massive amount of underdiagnosed women,” according to Letterle.
“This [disorder] was first researched in males, and the criteria developed around symptoms most commonly seen in boys,” she told Fox News Digital.
Initial research on ADHD in boys and men could have led to the misdiagnosis in women, one mental health expert suggested. (iStock)
“These are also the most overtly obvious symptoms — like hyperactivity, inability to sit still, disruption and difficulty focusing, often in the classroom — that lead to associated behavioral issues,” Letterle added.
While some women do experience these hyperactive symptoms, they are not the most prevalent symptoms and they look different when they do occur, according to Letterle.
“Women tend to exhibit symptoms that are more internalized,” she said.
“For instance, their inattention is much harder to recognize than boys, as it can be displayed as daydreaming or inward distraction.”
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Letterle pointed out the “external fallout” of these ADHD symptoms in girls — which results in “high rates of anxiety” due to missed information at school.
In many cases, girls have to work twice as hard to retain information and meet academic standards as their peers, and they experience low levels of confidence stemming from these difficulties, she added.
Girls with ADHD can experience “high levels of anxiety,” said a mental health expert. (iStock)
“That is subjectively a lot harder to identify than distracted boys, who are poking the individual next to them as they struggle to maintain focus.”
These variants lead to a “massive difference in diagnostic rates” between young girls and boys, Letterle said.
Boys are often diagnosed and treated faster than girls because their symptoms are easier to identify, she added.
Personalized coping
One of the best ways to cope with ADHD is to educate yourself, or your child, on the best way to function in different environments, said Nasta.
Some of the strategies she recommended include practicing mindfulness and self-awareness, and coming up with the best game plan in any given situation.
Stress management is another great coping tool, especially for boys, added Nasta.
Allowing kids with ADHD the time to release stress is an important coping technique, experts say. (iStock)
For kids, stress management can mean participating in leisure activities or hobbies like playing video games or hanging out with friends.
“It’s about allowing them to let that energy go in a more supportive way,” Nasta said.
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ADHD in boys and girls can be difficult for caretakers — parents, guardians and even teachers — to identify when they lack the “appropriate tools” to make “more accurate referrals,” Letterle noted.
To overcome that challenge, Nasta encouraged caretakers to “listen more.”
“If you’re really paying attention and your kid’s trying, this could be a neurological or neurodevelopmental concern versus them just struggling with emotions,” she said.
In young boys, ADHD shows up as “unnecessary” hyperactive energy; they “don’t have the capacity to not do anything,” according to experts. (iStock)
It might be helpful for parents to “be more curious” and ask their children questions about their feelings when they are overwhelmed, Nasta suggested.
“What do you experience when you’re overwhelmed? Are you able to focus or pay attention to your teacher? Do you notice what your thoughts are doing?” she listed as example questions.
“If it sounds really concerning and intrusive, I would say that’s the point of … seeing a professional.”
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Early ADHD intervention is “critical for reducing suicide rates, job instability and substance abuse in those left untreated,” Letterle said.
“The diagnostic process has been left largely to subjective rating scales, creating a desperate need for clinicians to start adopting a more data-driven approach to symptom measurement,” she added.
Impairments in managing basic hygiene, finances, academic or communication skills could signal the need for ADHD evaluation, according to experts. (iStock)
“Objective data compares performance in the three core symptom areas against age- and sex-matched controls without ADHD — meaning women are compared to other women to improve the ability to accurately identify their diagnosis,” the expert said.
When to seek help
While the term “ADHD” is often tossed around to describe when someone is feeling unfocused, Nasta listed a few warning signs that could point to an actual diagnosis.
The expert said to monitor daily responsibilities such as hygiene, finances, academics and even basic social skills such as listening and communication.
“If you notice impairments and deficits in any of those, I would say that would be the time to talk to somebody,” she advised.
For people who are unsure of their symptoms, Letterle recommended seeking out a provider who uses objective data in a comprehensive evaluation.
“[This] would help to better ensure not only a more accurate diagnosis, but also one that helps eliminate the bias that often leads to high rates of underdiagnosis or misdiagnosis in women,” she said.
For more Health articles, visit foxnews.com/health.
Health
Origin of deadly cancer affecting young adults revealed in alarming report
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As colorectal cancer (CRC) is now the leading cause of cancer death in adults under 50, a new report reveals some surprising shifts in the incidence of the disease.
Although rates of CRC have been declining among seniors, those 65 and under are facing a rise in diagnoses, according to a report titled Colorectal Cancer Statistics, 2026, from the American Cancer Society.
Adults 65 and younger comprise nearly half (45%) of all new colorectal cancer cases — a significant increase from 27% in 1995, states the report, which was published in CA: A Cancer Journal for Clinicians.
The disease is rising fastest among adults 20 to 49 years old, at a rate of 3% per year.
Colorectal cancer is now the leading cause of cancer death in adults under 50. (iStock)
Among adults 50 and under, 75% of colorectal cancers are diagnosed at an advanced stage. Half of the diagnoses in that age range are made between the ages of 45 and 49. Although that age group is eligible to receive routine screenings, just 37% do so.
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The report also revealed that rectal cancer is on the rise, now accounting for about one-third (32%) of all CRC cases — an increase from 27% in the mid-2000s.
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“After decades of progress, the risk of dying from colorectal cancer is climbing in younger generations of men and women, confirming a real uptick in disease because of something we’re doing or some other exposure,” said Rebecca Siegel, senior scientific director, surveillance research at the American Cancer Society and lead author of the report, in a press release.
Among adults 50 and under, 75% of colorectal cancers are diagnosed at an advanced stage. Half of the diagnoses in that age range are made between the ages of 45 and 49. (iStock)
“We need to redouble research efforts to understand the cause, but also circumvent deaths through earlier detection by educating clinicians and the general public about symptoms and increasing screening in people 45-54 years.”
It is projected that 158,850 new cases of colorectal cancer will be diagnosed this year, and that the disease will cause 55,230 deaths, per the report.
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More than half of CRC cases can be linked to high-risk behaviors, the researchers said. Those include lack of nutrition, high alcohol consumption, smoking, lack of exercise and obesity.
“These findings further underscore that colorectal cancer is worsening among younger generations and highlight the immediate need for eligible adults to begin screening at the recommended age of 45,” said Dr. William Dahut, chief scientific officer at the American Cancer Society.
When the disease is caught at a local (early) stage, the five-year survival rate is 95%. (iStock)
“The report also shines a light on the crucial importance of continued funding for research to help discover new therapies to treat the disease and advance patient care.”
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When the disease is caught at a local (early) stage, the five-year survival rate is 95%, the report stated.
Health
Aging process could accelerate due to ‘forever chemicals’ exposure, study finds
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A new study suggests that middle-aged men may be more vulnerable to faster biological aging, potentially linked to exposure to “forever chemicals.”
The research, published in the journal Frontiers in Aging, examined how perfluoroalkyl and polyfluoroalkyl substances, more commonly known as PFAS, could impact aging at the cellular level.
PFAS are synthetic chemicals commonly used in nonstick cookware, food packaging, water-resistant fabrics and other consumer products, the study noted.
Their chemical structure makes them highly resistant to breaking down, allowing them to accumulate in water, soil and the human body.
Chinese researchers analyzed blood samples from 326 adults enrolled in the U.S. National Health and Nutrition Examination Survey between 1999 and 2000.
A new study suggests that middle-aged men could face accelerated biological aging at the cellular level due to exposure to PFAS. (iStock)
The researchers measured levels of 11 PFAS compounds in participants’ blood and used DNA-based “epigenetic clocks” — tools that analyze chemical changes to DNA to estimate biological age — to determine how quickly their bodies were aging at the cellular level, the study stated.
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Two compounds, perfluorononanoic acid (PFNA) and perfluorooctanesulfonamide (PFOSA), were detected in 95% of participants.
Higher concentrations of those chemicals were associated with faster biological aging in men of certain age groups, but not in women.
“People should not panic.”
The compounds most strongly linked to accelerated aging were not the PFAS chemicals that typically receive the most public attention, the researchers noted.
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“The associations were strongest in adults aged 50 to 64, particularly in men,” Dr. Xiangwei Li, professor at Shanghai Jiao Tong University School of Medicine and the study’s corresponding author, told Fox News Digital.
“While this does not establish that PFAS cause aging, it suggests that these widely present ‘forever chemicals’ may be linked to molecular changes related to long-term health and aging.”
The study found that two of the compounds were detected in 95% of participants, and higher levels were linked to faster biological aging in men ages 50–64. (iStock)
Midlife may represent a more sensitive biological period, when the body becomes more vulnerable to age-related stressors, according to the researchers.
Lifestyle factors, such as smoking, may influence biological aging markers, potentially increasing vulnerability to environmental pollutants.
While Li said “people should not panic,” she does recommend looking for reasonable ways to reduce exposure.
That might mean checking local drinking water reports, using certified water filters designed to reduce PFAS, and limiting the use of stain- or grease-resistant products when alternatives are available.
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Meaningful reductions in PFAS exposure will likely depend on broader regulatory action and environmental cleanup efforts, Li added.
The researchers noted that midlife could be a particularly sensitive stage, when the body is more susceptible to stressors associated with aging. (iStock)
Study limitations
The researchers outlined several important limitations of the research, including that the findings show an association, but do not prove that PFAS directly causes accelerated aging.
“The study is cross-sectional, meaning exposure and aging markers were measured at the same time, so we cannot determine causality,” Li told Fox News Digital.
The study was also relatively small, limited to 326 adults age 50 or older, which means the findings may not apply to younger people or broader populations.
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Researchers measured PFAS levels using data collected between 1999 and 2000, and today’s exposure patterns may differ.
Li added that while PFAS is known to persist in the environment and the body, these results should be validated through larger, more recent studies that follow participants over time.
Health
Melissa Joan Hart, 49, Opens up About Weight Loss in Perimenopause
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