Health

A Federal Lab That Tracked Rising S.T.I.s Has Been Shuttered

Published

11 months ago

April 4, 2025

A Federal Lab That Tracked Rising S.T.I.s Has Been Shuttered

Drug-resistant gonorrhea, a form of the widespread sexually transmitted infection, is considered an urgent health threat worldwide. The United States has just lost its ability to detect it.

Among the Centers for Disease Control and Prevention employees fired on Tuesday were 77 scientists who, among other work, gathered samples of gonorrhea and other S.T.I.s from labs nationwide, analyzed the genetic information for signs of drug resistance, and readied the samples for storage at a secure facility.

No other researchers at the agency have the expertise, or the software, to continue this work. The abrupt halt has stranded about 1,000 samples of gonorrhea and other sexually transmitted pathogens that had not yet been processed, and perhaps dozens more headed to the agency.

There are as many as 30 freezers full of samples that now have no custodians, said one senior C.D.C. official who spoke on condition of anonymity for fear of retaliation.

“We were just really shut down midair, like there was no warning,” the official said. “It was just completely unplanned and chaotic.”

The C.D.C.’s work on S.T.I.s had taken on greater urgency in the past few years as rates of new infections soared. More than 2.4 million new S.T.I.s were diagnosed in 2023, about one million more than 20 years ago.

Nearly 4,000 babies were born with congenital syphilis in 2023. About 280 were stillborn or died soon after.

“Whoever got rid of the lab just doesn’t understand how important the lab is,” said another senior C.D.C. official who spoke on condition of anonymity.

About 600,000 new gonorrhea cases were diagnosed in the United States in 2023. The bacteria that cause gonorrhea, called Neisseria gonorrhoeae, spread through sexual contact to the genitals, rectum and throat. Left untreated, it can cause infertility and sterility, blindness in infants or even death.

Gonorrhea has become resistant to nearly every available antibiotic, leaving a single class that still snuffs it out. The most powerful defense combines a shot of ceftriaxone with azithromycin, but some evidence hints that gonorrhea is evolving to sidestep even that treatment.

Over more than 25 years, the C.D.C. lab archived about 50,000 gonorrhea samples — the largest collection in the world — which allow scientists to track how the pathogen has changed over time. It’s not clear what will happen to the samples.

One new public health strategy makes it even more important for the nation to track gonorrhea, said Dr. Jenell Stewart, an infectious diseases physician at Hennepin Healthcare in Minneapolis.

In a bid to combat resurgent syphilis and chlamydia, the C.D.C. recommended last year that gay and bisexual men and transgender women take doxycycline, a widely used antibiotic, within 72 hours of unprotected sex.

Cities like San Francisco and Seattle that had earlier endorsed the practice, called doxy-PEP, have already seen drastic drops in the rates of those infections.

But researchers are worried that widespread use of doxycycline might increase resistance to the entire class of antibiotics, called tetracyclines. A few studies suggest there may be reason to worry.

Harvard University researchers last month analyzed more than 14,000 genetic sequences generated by C.D.C. researchers and found that the proportion of gonorrhea bacteria with antibiotic resistance increased to more than 35 percent last year, from less than 10 percent in 2020.

The federal scientists who produced that data and made it publicly available have all been fired. “Without public health money and infrastructure, I’m not sure who if anyone will take up the torch to monitor gonorrhea resistance,” Dr. Stewart said.

“This is a huge loss,” she added.

Dr. Stewart and a colleague spent two years preparing the protocol and an app to study doxy-PEP in cisgender women and monitor gonorrhea resistance.

The study was supported by the Adolescent Medicine Trials Network, whose funding was slashed last month.

At least five other grants to study doxy-PEP have been terminated, along with a variety of grants at the National Institutes of Health aimed at preventing S.T.I.s, including H.I.V.

Any lab can test for S.T.I.s, but commercial tests cannot determine whether gonorrhea will respond to available treatments. C.D.C. scientists developed the only such test, and provided funding and training to a few dozen labs on the sophisticated testing.

Samples were sent to the agency for confirmation. Without the agency scientists, testing for drug sensitivity will most likely cease, several experts said.

“We cannot have a national surveillance system without a national lab,” said one scientist who leads a C.D.C.-funded lab but did not wish to be identified without authorization to speak to the media.

C.D.C. scientists were also helping to develop alternatives to the nation’s outdated syphilis test. It cannot identify an active infection, only whether someone was ever infected. The agency has three large contracts to develop new rapid syphilis tests.

But without expertise and the samples from C.D.C. scientists, it’s unclear whether that work can continue, said a senior official with knowledge of the situation.

The fired scientists had about 1,400 years of field experience between them. The official said, “These were highly trained people that are not replaceable easily.”

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Health

Common nighttime noise exposure may trigger heart problems, study suggests

Published

3 hours ago

February 28, 2026

Press Room

Common nighttime noise exposure may trigger heart problems, study suggests

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Living near heavy traffic could negatively impact your heart health.

A European study, published in the journal Environmental Research, found that exposure to nighttime road traffic noise is linked to changes in the blood, leading to worsened cholesterol and cardiovascular risks.

The researchers considered data from the U.K. Biobank, Rotterdam Study, and Northern Finland Birth Cohort 1966, including more than 272,000 adults over the age of 30, according to a press release.

Nighttime road noise exposure was estimated at all participants’ homes based on national noise maps. Researchers also took blood samples to measure the participants’ metabolic biomarkers for disease, then mapped the link between nightly noise levels and existence of biomarkers.

Exposure to loud noise was associated with increased concentrations of cholesterol-related biomarkers. (iStock)

The study found that people exposed to louder noise at night — especially sounds above 55 decibels — showed changes in 48 different substances in their blood. Twenty of these associations “remained robust” throughout all cohorts.

Exposure to loud noise was associated with increased concentrations of cholesterol-related biomarkers, especially LDL “bad” cholesterol, IDL (intermediate-density lipoprotein) and unsaturated fatty acids.

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As noise levels increased, starting at around 50 decibels, cholesterol markers rose steadily, the release stated.

The authors concluded that this study “provides evidence that nighttime road traffic noise exposure from 50 dB upward is associated with alterations in blood cholesterol and lipid profiles in adults.”

Researchers noted a link between traffic noise and cardiometabolic disease. (iStock)

Study co-author Yiyan He, doctoral researcher at the University of Oulu in Finland, noted that in this type of research, small effect sizes are expected, and environmental exposures such as traffic noise are “typically modest.”

SIMPLE NIGHTLY HABIT LINKED TO HEALTHIER BLOOD PRESSURE, STUDY SUGGESTS

“Despite this, we observed statistically robust and consistent associations across many biomarkers, especially those related to LDL and IDL lipoproteins,” she told Fox News Digital.

MISSING SLEEP MAY TAKE A HIDDEN TOLL ON YOUR BRAIN AND LONGEVITY, RESEARCH REVEALS

“We also identified a clear exposure-response pattern starting at around 50 dB, suggesting that metabolic changes become more evident as noise levels increase.”

This aligns with public health guidance, as the World Health Organization recommends lower nighttime noise limits at around 40 to 45 dB, Yiyan He added.

“This finding may clarify the association between traffic noise and cardiometabolic diseases,” the researchers wrote. (iStock)

“The 55 dB level is often used as an interim benchmark associated with substantial noise annoyance and sleep disturbance,” she said. “In our study, we observed associations not only at 55 dB, but also indications of effects emerging at around 50 dB.”

The strength and consistency of the cholesterol-related associations were surprising, as these changes are usually “subtle.”

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“Instead, we found consistent associations across multiple large European cohorts, which strengthens confidence that the findings may reflect real biological patterns,” Yiyan He went on. “We were also interested to see that effects were minimal below ~50 dB, suggesting a possible threshold-like pattern.”

HEART DISEASE THREAT PROJECTED TO CLIMB SHARPLY FOR KEY DEMOGRAPHIC

The researcher noted that these findings were consistent across genders, education levels and obesity status.

The study was restricted to White Europeans, which posed a limitation. There was also a lack of information on the fasting status in the UK Biobank.

Changes in cholesterol levels were more severe than researchers expected. (iStock)

“Fasting can influence levels of certain metabolites, particularly fatty acids,” Yiyan He said. “However, based on UK Biobank documentation, fewer than 10% of participants were fasting for at least eight hours, and our main findings focused on cholesterol-related biomarkers, which are generally less sensitive to short-term fasting.”

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The researchers also lacked information on bedroom location, indoor noise exposure and time spent at home.

“These factors may introduce non-differential exposure misclassification,” Yiyan He said. “Additionally, noise exposure estimates were based on participants’ temporary residential addresses at the time of blood sampling, without considering the duration of residence.”

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“Many of these limitations would tend to bias results toward the null, so the consistent associations we observed remain noteworthy.”

Experts recommend taking measures to limit traffic noise at night. (iStock)

Based on this latest research, Yiyan He noted that nighttime noise is a “health-relevant exposure,” not just “an annoyance.”

“Our findings suggest that nighttime traffic noise may subtly but consistently affect metabolic health,” she said. “While the changes in cholesterol and lipid levels for any one individual are small, traffic noise affects a very large number of people, which means the potential public health impact could be substantial.”

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The researcher recommends taking measures like improving sound insulation, using noise-reducing strategies and placing bedrooms on the quieter side of the home when possible.

“Because sleep is a key pathway linking noise to health, protecting the nighttime sleep environment is especially important,” she added.

Angelica Stabile is a lifestyle reporter for Fox News Digital.

Health

The Best Time To Drink Coffee for Weight Loss and a Faster Metabolism

Published

15 hours ago

February 27, 2026

Press Room

The Best Time To Drink Coffee for Weight Loss and a Faster Metabolism

The Best Time To Drink Coffee for Weight Loss and Fat Burn | Woman’s World

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