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Nearly 40% of cancers can be prevented with 3 lifestyle changes, study finds

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Nearly 40% of cancers can be prevented with 3 lifestyle changes, study finds

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Nearly half of cancers could be avoided by cutting out three major risk factors, a new study has revealed.

Research published this week in Nature Medicine identified that nearly 40% of global cancer cases are linked to tobacco (15% of new cases), infections (10%) and alcohol consumption (3%).

Overall, 7.1 million cancer diagnoses in 2022 were linked to 30 modifiable risk factors, according to the study.

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“The key here is that almost half of all cancers could be prevented by behavioral changes,” Dr. Marc Siegel, Fox News Digital senior medical analyst, told Fox News Digital.

Conducted by the World Health Organization and its International Agency for Research on Cancer (IARC), the study analyzed global cancer data across 185 countries, matching it with exposure data for the 30 risk factors.

Nearly half of cancers could be avoided by cutting out three major risk factors, a new study has revealed. (iStock)

Lung, stomach and cervical cancers accounted for nearly half of the cases that were linked to modifiable risks, with many linked to viruses and bacteria like the human papillomavirus (HPV), hepatitis B and C, and Helicobacter pylori (a common bacterium that infects the stomach lining).

“Preventable cancers of the cervix and throat are directly linked to the HPV virus and can be prevented by the HPV vaccine,” added Siegel, who was not involved in the study.

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DEADLY CANCER RISK SPIKES WITH CERTAIN LEVEL OF ALCOHOL CONSUMPTION, STUDY FINDS

Lung cancer, throat and GI cancers, and several others were linked to cigarette smoking, and alcohol was associated with breast, liver, colon and throat cancer, the doctor noted.

“Environmental factors are also key, varying by geography — 45% of new cancers could be prevented in men, and 30% in women,” he said.

Lung, stomach and cervical cancers accounted for nearly half of the cases that were linked to modifiable risks. (iStock)

Study author Hanna Fink, from the Cancer Surveillance Branch at IARC/WHO, said the main message is that many cancers can be prevented.

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“Almost four in 10 new cancer cases worldwide, which represent 7.1 million lives that don’t need to be changed by a cancer diagnosis, were linked to things we can change or modify through awareness and public-health action,” she told Fox News Digital.

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“These things include tobacco smoking, infections, alcohol consumption, excess body weight, air pollution, ultraviolet radiation and others.”

Looking ahead, the researchers recommend that stronger prevention strategies targeting tobacco use, infections, unhealthy body weight and alcohol use could substantially reduce global cancer cases.

“The key here is that almost half of all cancers could be prevented by behavioral changes.”

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“The study reinforces that cancer prevention works, and action is most effective at the population level,” Fink said. 

“Governments and communities play a crucial role by making healthy choices easier, for example, through higher tobacco and alcohol taxes, smoke-free policies, clear health warnings, safer workplaces, cleaner air, and affordable access to vaccination and screening. Individuals can support these by advocating for healthier environments and using available preventive services.”

Reducing the risk

The AIRC offers the following recommendations to minimize cancer risk.

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  • Do not smoke, and if you do smoke, seek help to quit.
  • Keep alcohol intake as low as possible, as “there is no safe level of alcohol for cancer risk.”
  • Aim for a healthy body weight over time with a balanced diet and regular physical activity.
  • Move more and sit less, as even small amounts of daily movement help.
  • Take advantage of vaccines, especially the HPV vaccination for young people and the hepatitis B vaccination.

Tobacco was linked to 15% of new cancer cases, making it the largest modifiable risk factor. (iStock)

“As a family physician, I try to help my patients understand how important their daily habits are in lowering their future cancer risk,” said Dr. Chris Scuderi, a cancer survivor and Florida-based family physician.

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The doctor’s key prevention targets include daily exercise, consistent and restorative sleep, a Mediterranean-style diet, regular doctor’s visits and sufficient rest.

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“Small daily wins add up to make a powerful difference over time,” added Scuderi, who also was not involved in the research. “It’s also essential to stay on top of your routine screenings, which your family physician can help you with.”

Potential limitations

The study did have some limitations. The researchers often used data from around 2012 due to the long delay between exposure and cancer, which means the data may not reflect the most recent behaviors or environments.

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“This is a necessary simplification, because in reality, latency can be longer or shorter depending on the cancer and the exposure,” Fink noted.

A doctor recommended daily exercise, consistent and restorative sleep, a Mediterranean-style diet, regular doctor’s visits and sufficient rest to help reduce risk. (iStock)

Siegel pointed out that cancer types vary by geographic region — for example, stomach cancer is more prominent in Asia — and the relationships between risk factors and cancer prevalence can differ between countries, populations and time periods.

“We rely on the best available data on how common each risk factor is in different countries and how strongly it is linked to cancer, but these data are not perfect and are weaker in some low- and middle-income countries,” Fink said.

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Finally, the study only looked at 30 risk factors with the strongest evidence and global data.

“Our estimate of ‘almost 40% of cancers are preventable’ is very likely conservative,” the researcher added. “Some other suspected causes, such as certain aspects of diet, could not be included because the science or the data are not yet robust enough at a global level.” 

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Loneliness may be silently eroding your memory, new research reveals

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Loneliness may be silently eroding your memory, new research reveals

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Feeling lonely may take a toll on older adults’ memory — but it may not speed up cognitive decline, according to a new study.

Researchers from Colombia, Spain and Sweden analyzed data from more than 10,000 adults ages 65 to 94 across 12 European countries and found those who reported higher levels of loneliness did worse on memory tests at the start of the study, according to research published this month in the journal Aging & Mental Health.

Over a seven-year period, however, memory decline occurred at a similar rate regardless of how lonely participants felt.

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“The finding that loneliness significantly impacted memory, but not the speed of decline in memory over time was a surprising outcome,” lead author Dr. Luis Carlos Venegas-Sanabria of the School of Medicine and Health Sciences at the Universidad del Rosario said in a statement.

Loneliness may be linked to memory performance in older adults, a new study suggests. (iStock)

“It suggests that loneliness may play a more prominent role in the initial state of memory than in its progressive decline,” Venegas-Sanabria said, adding that the findings highlight the importance of addressing loneliness as a factor in cognitive performance.

The findings add to debate about whether loneliness contributes to dementia risk. While loneliness and social isolation are often considered risk factors for cognitive decline, research results have been mixed.

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The study looked at data from the long-running Survey of Health, Ageing and Retirement in Europe (SHARE), which tracked 10,217 older adults between 2012 and 2019. Participants were asked to recall words immediately and after a delay to measure memory performance.

Social isolation and loneliness could play a surprising role in cognitive health among seniors. (iStock)

Loneliness was assessed using three questions about how often participants felt isolated, left out or lacking companionship.

About 8% of participants reported high levels of loneliness at the outset. That group tended to be older, more likely to be female and more likely to have conditions such as depression.

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Researchers found that those with higher loneliness had lower scores on both immediate and delayed memory tests at baseline. Still, all groups — regardless of loneliness level — experienced similar declines in memory over time.

The results suggest loneliness may not directly accelerate the progression of memory loss, though it remains linked to poorer cognitive performance overall.

Researchers look at a brain scan at the National Institutes of Health in Bethesda, Maryland. (Saul Loeb/AFP/Getty Images)

Experts warn, however, that the findings should not be interpreted to mean loneliness is harmless.

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“The finding that lonely older adults start with worse memory but don’t decline faster is actually the most interesting part of the paper, and I think it’s easy to misread,” said Jordan Weiss, Ph.D., a scientific advisor and aging expert at Assisted Living Magazine and a professor at NYU Grossman School of Medicine.

“It likely means loneliness does its damage earlier in life, well before people show up in a study like this at 65-plus,” Weiss told Fox News Digital.

By older age, long-term social patterns may already be established, making it harder to detect when the effects of loneliness first took hold, an aging expert says. (iStock)

He suggested that by older age, long-term social patterns may already be established, making it harder to detect when the effects of loneliness first took hold.

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“By the time you’re measuring someone in their late 60s, decades of social connection patterns are already baked in,” he said.

Weiss, who was not involved in the research, added that loneliness may coincide with other health conditions, and noted that participants who felt more isolated also had higher rates of depression, high-blood pressure and diabetes. The link, he said, may reflect a cluster of health risks rather than a direct cause.

“While they can go hand-in-hand, it’s not clear that loneliness contributes to dementia,” a psychotherapist says. (iStock)

Amy Morin, a Florida-based psychotherapist and author, said the findings reflect a broader pattern in research on loneliness and brain health, and that the relationship may be more complex than it appears.

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“The evidence shows there’s a link between loneliness and cognitive decline but there’s no direct evidence of a cause and effect relationship,” she said. “So while they can go hand-in-hand, it’s not clear that loneliness contributes to dementia.”

Morin added that loneliness, which can fluctuate, may not be the root of the problem, but rather a symptom of other underlying mental or physical health issues.

Researchers suggested screening for loneliness be incorporated into routine cognitive assessments as one way to support healthy aging. (iStock)

She said staying socially and mentally engaged is crucial for overall brain health.

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“It’s important to be proactive about social activities,” Morin said. “Joining a book club, having coffee with a friend, or attending faith-based services can be a powerful way to maintain connections in older age.”

The researchers also suggested screening for loneliness be incorporated into routine cognitive assessments as one way to support healthy aging.

Fox News Digital reached out to the researchers for comment.

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Eat More To Lose Weight? She Dropped 55 Pounds by Having 5 Meals a Day

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Eat More To Lose Weight? She Dropped 55 Pounds by Having 5 Meals a Day


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Eat More To Lose Weight? How Small Meals Boost Fat Burn




















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Intermittent fasting’s real benefit may come after you start eating again

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Intermittent fasting’s real benefit may come after you start eating again

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Research continues to uncover new details on how fasting may help extend life.

A new study published in the journal Nature Communications investigated how intermittent fasting can boost longevity in small worms often used in aging research.

Researchers from the University of Texas Southwestern Medical Center in Dallas compared worms that were fed normally to those that underwent a 24-hour fast in early adulthood and were then fed again, according to a press release.

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The scientists measured a variety of factors, including stored fat, gene activity related to fat metabolism and lifespan.

The results showed that the life-boosting benefit did not depend on the fasting itself but on the body’s behavior after eating again.

Experts say sustainability is key when choosing a long-term weight-loss strategy. (iStock)

Study lead Peter Douglas, associate professor of molecular biology and a member of the Hamon Center for Regenerative Science and Medicine at UT Southwestern, suggested that these discoveries “shift the focus toward a neglected side of the metabolic coin – the re-feeding phase.”

“Our data suggest that the health-promoting effects of intermittent fasting are not merely a product of the fast itself, but are dependent on how the metabolic machinery recalibrates during the subsequent transition back to a fed state,” he said.

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“Our findings bridge a gap between lipid metabolism and aging research,” he added. “By targeting aging, the single greatest risk factor for human disease, we move beyond treating isolated conditions toward a preventive model of medicine that enhances quality of life for all individuals.”

Lauri Wright, director of nutrition programs at the University of South Florida’s College of Public Health, called this a “high-quality” study that adds an “important nuance to how we think about fasting and longevity.”

Intermittent fasting typically involves limiting meals to an eight-hour daily window or fasting every other day. (iStock)

The benefits of the refeeding phase after fasting were “especially interesting,” Wright, who was not involved in the study, told Fox News Digital.

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“The researchers showed that longevity was linked to the body’s ability to turn off fat breakdown after fasting, allowing cells to restore energy balance,” she reiterated.

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“From a scientific standpoint, that’s a meaningful shift because it suggests fasting is not just about burning fat, but about metabolic flexibility.”

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Fasting may support longevity through triggering metabolic switching, enhancing cellular repair and stress resistance and improving markers like insulin sensitivity, research shows.

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Limitations and cautions

Although this study provides “important insight” on the power of refeeding, Wright noted that the findings should be approached with caution, as the study was done on worms and cannot always be translated to humans.

“Additionally, it explains how a process might work in a controlled lab condition rather than real-world eating behaviors,” she added as a limitation. “Finally, the study is short-term and doesn’t give us the long-term translation on lifespan outcomes.”

The review found intermittent fasting was barely more effective than doing nothing, according to the study authors. (iStock)

Wright cautioned that fasting is “not a magic solution for longevity, and how you eat overall matters more than when you eat.”

“I advise, first and foremost, to focus on diet quality, including a variety of fruits and vegetables, healthy fats and minimally processed foods,” she said.

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For those who are considering fasting, it’s better to stick with a moderate plan — like a 12- to 14-hour overnight fast — rather than going to extremes, Wright said. After fasting, she recommends focusing on well-balanced meals.

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Several groups of people should be cautioned against fasting, according to Wright, including those with diabetes who are on insulin or hypoglycemic medications, those who are pregnant or breastfeeding, anyone with a history of eating disorders and older adults at risk of malnutrition.

Anyone considering intermittent fasting should consult with a doctor before starting.

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