Health
Fatal bacterial infections surging in Japan with unknown cause, reports says
Japan is reporting a spike in potentially fatal bacterial infections.
Cases of streptococcal toxic shock syndrome (STSS), which is caused by Group A Streptococcus bacteria, have reached 977 in the country so far this year as of June 2, according to Japan’s National Institute of Infectious Diseases.
That is almost triple the number of cases reported at this time last year.
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The cause for the surge is not known.
It could be linked to weakened immunity after the COVID pandemic, according to Tokyo Women’s Medical University professor Ken Kikuchi.
Takeshita Street in Harajuku is one of the most popular streets in Tokyo. Japan is currently reporting a spike in potentially fatal bacterial infections. (iStock)
“We can boost immunity if we are constantly exposed to bacteria, but that mechanism was absent during the coronavirus pandemic,” Kikuchi told NKH World Japan.
“So, more people are now susceptible to infection, and that may be one reason for the sharp rise in cases.”
“It can lead to sepsis and death if not treated quickly with antibiotics and fluids.”
Thomas Moore, M.D., a clinical professor at the University of Kansas School of Medicine-Wichita, said he’s not convinced the pandemic is the culprit.
“I can’t conclusively say that that’s incorrect, but this is the kind of thing where it spreads more easily when people are crowded together, like they can be in Tokyo,” he said in an interview with Fox News Digital.
Streptococcal toxic shock syndrome (STSS) is caused by Group A Streptococcus bacteria. (iStock)
“So it’s not so much an effect of weakened immunity as much as it is a very brisk immunity — a brisk immunologic reaction that results in the illness.”
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Dr. Marc Siegel, clinical professor of medicine at NYU Langone Medical Center and a Fox News medical contributor, warned that STSS can overcome an immune system that isn’t functioning properly.
“It’s similar to toxic shock syndrome, but with strep instead of staph,” he told Fox News Digital.
What is STSS?
Streptococcal toxic shock syndrome is a rare but serious bacterial infection, as defined by the U.S. Centers for Disease Control and Prevention (CDC).
It occurs when the Group A Streptococcus bacteria travels into deep tissues and the bloodstream.
“Everybody’s familiar with strep throat, and that’s generally the same organism,” said Moore.
“The main difference between common, regular strep throat and this particular condition is a specific gene that produces a toxin that results in this severe outbreak,” an expert said. (iStock)
“The main difference between common, regular strep throat and this particular condition is a specific gene that produces a toxin that results in this severe outbreak.”
Although STSS usually does not spread from person to person, the less severe group A strep infection — which can lead to STSS if it spreads to the tissues or bloodstream — is very contagious.
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Initial symptoms usually include fever and chills, muscle aches, and nausea and vomiting, per the CDC.
Within a day or two, blood pressure starts to drop, which can lead to more dangerous effects like elevated heart rate, rapid breathing, sepsis, tissue death and organ failure.
People with STSS require hospitalization and immediate medical care, including intravenous fluids and other treatments for shock and organ failure, the CDC said. (iStock)
STSS can be fatal, with about one in 10 patients dying from the infection.
Although there is no specific test for STSS, it is diagnosed based on the presence of group A strep, low blood pressure and issues with two or more organs (blood, kidney, liver, lung, skin or soft tissue).
Higher-risk groups include older adults over 65, people with open wounds, and those with diabetes or alcohol use disorder, according to the CDC.
People with STSS require hospitalization and immediate medical care, including intravenous fluids and other treatments for shock and organ failure, the agency stated on its website.
Frequent hand-washing is one of the most effective prevention tactics, doctors say. (iStock)
“It can lead to sepsis and death if not treated quickly with antibiotics and fluids,” Siegel warned.
In severe cases, he said, patients may require surgery to remove infected tissue or even limb amputation.
Prevention tips
Although there is no vaccine for Group A strep infections, the CDC recommends implementing prevention tips — chiefly limiting exposure to those who are infected.
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It is also important to properly clean and care for wounds and fungal infections.
“If it gets on your skin where you have a break of some kind, it can invade the lymphatic system and cause infection,” Moore warned.
It is important to properly clean and care for wounds and fungal infections to prevent infection, according to experts. (iStock)
The doctor typically sees this in people who have swelling of their legs due to obesity, diabetes or a condition such as athlete’s foot, he said.
“When streptococcal infection gets in through other parts of the body, like the legs or a surgical incision, that can be pretty serious,” he said.
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Frequently washing hands, following proper coughing and sneezing etiquette, and thoroughly washing all dishes after use can help prevent spread, per the CDC.
Treatment with antibiotics also minimizes contagion.
Health
Common nighttime noise exposure may trigger heart problems, study suggests
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Living near heavy traffic could negatively impact your heart health.
A European study, published in the journal Environmental Research, found that exposure to nighttime road traffic noise is linked to changes in the blood, leading to worsened cholesterol and cardiovascular risks.
The researchers considered data from the U.K. Biobank, Rotterdam Study, and Northern Finland Birth Cohort 1966, including more than 272,000 adults over the age of 30, according to a press release.
Nighttime road noise exposure was estimated at all participants’ homes based on national noise maps. Researchers also took blood samples to measure the participants’ metabolic biomarkers for disease, then mapped the link between nightly noise levels and existence of biomarkers.
Exposure to loud noise was associated with increased concentrations of cholesterol-related biomarkers. (iStock)
The study found that people exposed to louder noise at night — especially sounds above 55 decibels — showed changes in 48 different substances in their blood. Twenty of these associations “remained robust” throughout all cohorts.
Exposure to loud noise was associated with increased concentrations of cholesterol-related biomarkers, especially LDL “bad” cholesterol, IDL (intermediate-density lipoprotein) and unsaturated fatty acids.
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As noise levels increased, starting at around 50 decibels, cholesterol markers rose steadily, the release stated.
The authors concluded that this study “provides evidence that nighttime road traffic noise exposure from 50 dB upward is associated with alterations in blood cholesterol and lipid profiles in adults.”
Researchers noted a link between traffic noise and cardiometabolic disease. (iStock)
Study co-author Yiyan He, doctoral researcher at the University of Oulu in Finland, noted that in this type of research, small effect sizes are expected, and environmental exposures such as traffic noise are “typically modest.”
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“Despite this, we observed statistically robust and consistent associations across many biomarkers, especially those related to LDL and IDL lipoproteins,” she told Fox News Digital.
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“We also identified a clear exposure-response pattern starting at around 50 dB, suggesting that metabolic changes become more evident as noise levels increase.”
This aligns with public health guidance, as the World Health Organization recommends lower nighttime noise limits at around 40 to 45 dB, Yiyan He added.
“This finding may clarify the association between traffic noise and cardiometabolic diseases,” the researchers wrote. (iStock)
“The 55 dB level is often used as an interim benchmark associated with substantial noise annoyance and sleep disturbance,” she said. “In our study, we observed associations not only at 55 dB, but also indications of effects emerging at around 50 dB.”
The strength and consistency of the cholesterol-related associations were surprising, as these changes are usually “subtle.”
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“Instead, we found consistent associations across multiple large European cohorts, which strengthens confidence that the findings may reflect real biological patterns,” Yiyan He went on. “We were also interested to see that effects were minimal below ~50 dB, suggesting a possible threshold-like pattern.”
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The researcher noted that these findings were consistent across genders, education levels and obesity status.
The study was restricted to White Europeans, which posed a limitation. There was also a lack of information on the fasting status in the UK Biobank.
Changes in cholesterol levels were more severe than researchers expected. (iStock)
“Fasting can influence levels of certain metabolites, particularly fatty acids,” Yiyan He said. “However, based on UK Biobank documentation, fewer than 10% of participants were fasting for at least eight hours, and our main findings focused on cholesterol-related biomarkers, which are generally less sensitive to short-term fasting.”
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The researchers also lacked information on bedroom location, indoor noise exposure and time spent at home.
“These factors may introduce non-differential exposure misclassification,” Yiyan He said. “Additionally, noise exposure estimates were based on participants’ temporary residential addresses at the time of blood sampling, without considering the duration of residence.”
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“Many of these limitations would tend to bias results toward the null, so the consistent associations we observed remain noteworthy.”
Experts recommend taking measures to limit traffic noise at night. (iStock)
Based on this latest research, Yiyan He noted that nighttime noise is a “health-relevant exposure,” not just “an annoyance.”
“Our findings suggest that nighttime traffic noise may subtly but consistently affect metabolic health,” she said. “While the changes in cholesterol and lipid levels for any one individual are small, traffic noise affects a very large number of people, which means the potential public health impact could be substantial.”
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The researcher recommends taking measures like improving sound insulation, using noise-reducing strategies and placing bedrooms on the quieter side of the home when possible.
“Because sleep is a key pathway linking noise to health, protecting the nighttime sleep environment is especially important,” she added.
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