World
Sickle cell patient offers hope to Ugandan community where disease is prevalent
- Barbara Nabulo, a sickle cell disease patient, has emerged as a dedicated advocate for others facing the same condition in rural Uganda.
- Despite her own challenges with the disease, Nabulo serves as a counselor to fellow patients, offering them encouragement and hope.
- Nabulo regularly visits sickle cell patients in the hospital ward, providing them with guidance and reassurance.
Barbara Nabulo was one of three girls in her family. But when a sister died, her mother wailed at the funeral that she was left with just one and a half daughters.
The half was the ailing Nabulo, who at age 12 grasped her mother’s meaning.
“I hated myself so much,” Nabulo said recently, recalling the words that preceded a period of sickness that left her hospitalized and feeding through a tube.
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The scene underscores the lifelong challenges for some people with sickle cell disease in rural Uganda, where it remains poorly understood. Even Nabulo, despite her knowledge of how the disease weakens the body, spoke repeatedly of “the germ I was born with.”
Barbara Nabulo cleans clothes at her home in Busamaga-Mutukula village in Mbale, Uganda, on April 25, 2024. Nabulo, a sickle cell disease patient, has emerged as a dedicated advocate for others facing the same condition. (AP Photo/Hajarah Nalwadda)
Sickle cell disease is a group of inherited disorders in which red blood cells — normally round — become hard, sticky and crescent shaped. The misshapen cells clog the flow of blood, which can lead to infections, excruciating pain, organ damage and other complications.
The disease, which can stunt physical growth, is more common in malaria-prone regions, notably Africa and India, because carrying the sickle cell trait helps protect against severe malaria. Global estimates of how many people have the disease vary, but some researchers put the number between 6 million and 8 million, with more than 5 million living in sub-Saharan Africa.
The only cure for the pain sickle cell disease can cause is a bone marrow transplant or gene therapies like the one commercially approved by the U.S. Food and Drug Administration in December. A 12-year-old boy last week became the first person to begin the therapy.
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Those options are beyond the reach of most patients in this East African nation where sickle cell disease is not a public health priority despite the burden it places on communities. There isn’t a national database of sickle cell patients. Funding for treatment often comes from donor organizations.
In a hilly part of eastern Uganda that’s a sickle cell hot spot, the main referral hospital looks after hundreds of patients arriving from nearby villages to collect medication. Many receive doses of hydroxyurea, a drug that can reduce periods of severe pain and other complications, and researchers there are studying its effectiveness in Ugandan children.
Nabulo, now 37, is one of the hospital’s patients. But she approaches others like her as a caregiver, too.
After dropping out in primary school, she has emerged in recent years as a counselor to fellow patients, speaking to them about her survival. Encouraged by hospital authorities, she makes weekly visits to the ward that has many children watched over by exhausted-looking parents.
Nabulo tells them she was diagnosed with sickle cell disease at two weeks old, but now she is the mother of three children, including twins.
Such a message gives hope to those who feel discouraged or worry that sickle cell disease is a death sentence, said Dr. Julian Abeso, head of pediatrics at Mbale Regional Referral Hospital.
Some men have been known to divorce their wives — or neglect them in search of new partners — when they learn that their children have sickle cell disease. Frequent community deaths from disease complications reinforce perceptions of it as a scourge.
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Nabulo and health workers urge openness and the testing of children for sickle cell as early as possible.
Abeso and Nabulo grew close after Nabulo lost her first baby hours after childbirth in 2015. She cried in the doctor’s office as she spoke of her wish “to have a relative I can call mine, a descendant who can help me,” Abeso recalled.
“At that time, people here were so negative about patients with sickle cell disease having children because the complications would be so many,” the doctor said.
Nabulo’s second attempt to have a child was difficult, with some time in intensive care. But her baby is now a 7-year-old boy who sometimes accompanies her to the hospital. The twin girls came last year.
Speaking outside the one-room home she shares with her husband and children, Nabulo said many people appreciate her work despite the countless indignities she faces, including unwanted stares from people in the streets who point to the woman with “a big head,” one manifestation in her of the disease. Her brothers often behave as if they are ashamed of her, she said.
Once, she heard of a girl in her neighborhood whose grandmother was making frequent trips to the clinic over an undiagnosed illness in the child. The grandmother was hesitant to have the girl tested for sickle cell when Nabulo first asked her. But tests later revealed the disease, and now the girl receives treatment.
“I go to Nabulo for help because I can’t manage the illness affecting my grandchild,” Kelemesiya Musuya said. “She can feel pain, and she starts crying, saying, ‘It is here and it is rising and it is paining here and here.’”
Musuya sometimes seeks reassurance. “She would be asking me, ‘Even you, when you are sick, does it hurt in the legs, in the chest, in the head?’ I tell her that, yes, it’s painful like that,” Nabulo said.
Nabulo said she was glad that the girl, who is 11, still goes to school.
The lack of formal education is hurtful for Nabulo, who struggles to write her name, and a source of shame for her parents, who repeatedly apologize for letting her drop out while her siblings studied. One brother is now a medical worker who operates a clinic in a town not far away from Nabulo’s home
“I am very happy to see her,” said her mother, Agatha Nambuya.
She recalled Nabulo’s swelling head and limbs as a baby, and how “these children used to die so soon.”
But now she knows of others with sickle cell disease who grew to become doctors or whatever they wanted to be. She expressed pride in Nabulo’s work as a counselor and said her grandchildren make her feel happy.
“At that time,” she said, recalling Nabulo as a child, “we didn’t know.”
World
Iran War Live Updates: Trump Officials and Iran Plan New Talks Despite Mixed Messages
The United States military last week extended its blockade on vessels coming in and out of Iranian ports to the waters of the wider world, declaring that it would pursue any ship aiding Iran, regardless of location on the high seas or flag.
The U.S. “will actively pursue any Iranian-flagged vessel or any vessel attempting to provide material support to Iran,” Gen. Dan Caine, chairman of the Joint Chiefs of Staff, said Thursday, noting that the American troops beyond the Middle East will engage in operations to thwart Iranian shipping.
The extension of the blockade comes as the economically vital Strait of Hormuz remains all but closed to commercial traffic and the two-week cease-fire between the United States and Iran nears an end. The move aligns longstanding American economic policies targeting Iran with the current military campaign against it, maritime and military law experts say.
But it raises a host of legal and practical questions.
“War is a messy thing not just on the combat side but under national and international law,” said James R. Holmes, chair of maritime strategy at the Naval War College.
“From a legal standpoint, a blockade is an act of war, so the blockade probably is legal to the extent Operation Epic Fury is,” he said using the name of the U.S. military campaign against Iran.
Since Congress has not declared war against Iran, no formal state of war exists between the United States and the Islamic Republic. But Mr. Holmes noted that “undeclared wars are more the rule than the exception in U.S. history,” with joint resolutions of Congress, United Nations Security Council resolutions and NATO decisions invoked to justify fighting.
“This campaign may be more unilateral than most, but it is not without precedent,” he said.
Under international law, the legality of the blockade is “more ambiguous,” said Jennifer Kavanagh, a senior fellow and director of military analysis at Defense Priorities, a foreign policy think tank in Washington.
For a blockade to be legal, Ms. Kavanagh said, it must be “effective,” meaning that it is both enforceable and enforced. Some would argue that a “‘global blockade’ is not permissible in conception” because it is overly broad, she said.
Still, expansive blockades have taken place throughout history, including during World War II, when states enforced naval blockades worldwide other than in neutral territorial seas. Over the centuries before that, the British blockaded France throughout the Revolutionary and Napoleonic Wars, and during the War of American Independence, the colonies and their allies raided British shipping as far away as the Indian Ocean.
Enforcing expansive blockades is difficult, however.
“The seven seas are a big place, and the largest navy or coast guard is tiny by comparison,” Mr. Holmes said. Whether the U.S. blockade ultimately is deemed “effective,” legally speaking, will depend on whether the U.S. has enough assets like ships, aircraft, boarding crews and intelligence gathering to enforce it.
The blockade does not have to be “airtight” to meet the legal test, Mr. Holmes said, and assessing its effectiveness will be tough for outside observers in any case.
Enforcement may also have to be somewhat selective, he suggested.
“Now, it is possible our leadership might quietly let a ship proceed when it suits the national interest,” Mr. Holmes said. “For instance, with a summit coming up between President Trump and General Secretary Xi” — Mr. Trump is to meet with China’s leader, Xi Jinping, in May — “Washington might not want to ruffle feathers by obstructing China’s oil imports.”
The expanded blockade is part of a longstanding economic campaign against Iran, but it represents something of a tactical change for the Trump administration.
Earlier in the war, the United States temporarily lifted sanctions on Iranian oil at sea to ease the pressure on global energy prices. And before imposing a blockade on Iranian ports last week, the U.S. allowed Iranian tankers to transit the Strait of Hormuz for the same reason.
Now Washington seems to be returning its focus to keeping pressure on Iran.
“The blockade is a wartime extension of existing U.S. economic sanctions against the Iranian regime,” said James Kraska, professor of international maritime law and a visiting professor at Harvard Law School. In peacetime, he said, the sanctions were a “powerful tool to weaken the Iranian economy.” Now, he said, the blockade serves as a “kinetic expansion.”
General Caine’s announcement about the expanded naval blockade came one day after Treasury Secretary Scott Bessent announced “Operation Economic Fury,” an effort he called the “financial equivalent” of a bombing campaign. It includes secondary sanctions on institutions internationally, like banks, that have dealings with Iran.
The expanded blockade “marks a notable escalation by the United States,” said Ms. Kavanagh.
Still, she said, it is unlikely to significantly change Iranian calculations.
“For Iran, this war is existential and it is not going to cave easily or quickly,” she said. “Economic pressure may work over the very long term, but Trump seems too impatient for a deal to wait it out.”
World
Deadly shooting at historic tourist site leaves one dead, several injured as motive unclear
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A Canadian woman was shot and killed Monday, and several others were injured, before a gunman took his own life at Mexico’s popular Teotihuacan pyramids.
Mexican officials said that four people were wounded by gunfire and two others sustained injuries from falls. Among the injured were tourists from Colombia, Russia, and Canada, according to local government reports via The Associated Press.
A firearm, a bladed weapon, and live cartridges were found at the scene, Mexico’s Security Cabinet confirmed on social media.
The Pyramid of the Moon and the Pyramid of the Sun are seen along with smaller structures lining the Avenue of the Dead in Teotihuacan, Mexico, on March 19, 2020. A gunman killed a Canadian tourist and injured several other before taking his own life at the popular site, authorities said Monday. (Rebecca Blackwell/AP)
“Our thoughts are with their family and loved ones, and consular officials are in touch to provide assistance,” Canada’s foreign ministry said in a social media post.
Mexican President Claudia Sheinbaum wrote on social media that the shooting would be thoroughly investigated and that she was in contact with the Canadian Embassy.
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Mexican President Claudia Sheinbaum speaks during her morning press conference at the National Palace in Mexico City on Jan. 5, 2026. (Raquel Cunha/Reuters)
“What happened today in Teotihuacan deeply pains us,” she wrote. “I express my most sincere solidarity with the affected individuals and their families.”
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Sheinbaum said she has instructed the Security Cabinet to investigate the events and provide all necessary support to the victims.
People visit the Pyramid of the Sun in the pre-Hispanic city of Teotihuacan near Mexico City, Mexico, on March 21, 2024, following the spring equinox. (Henry Romero/Reuters)
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“Personnel from the Secretariat of the Interior and the Secretariat of Culture are already heading to the site to provide assistance and accompaniment, along with local authorities,” she said. “I am closely following the situation, and we will continue to provide timely updates through the Security Cabinet.”
The pre-Hispanic city, located just outside Mexico City, was once one of the most significant cultural centers in Mesoamerica.
Fox News Digital has reached out to Canada’s foreign ministry for comment.
World
‘Predators’: Amnesty slams Netanyahu Putin, Trump, as human rights decline
London, United Kingdom – Israel, Russia and the United States are leading the destruction of global human rights, Amnesty International has said, describing the three countries’ leaders as “voracious predators” intent upon economic and political domination.
“A global environment where primitive ferocity could flourish has been long in the making,” Agnes Callamard, the head of the global rights group, wrote in an annual report on the state of the world’s human rights that was released on Tuesday.
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In 2025, “sharp U-turns were taken away from the international order that had been imagined out of the ashes of the Holocaust and the utter destruction of world wars, and constructed slowly and painfully, albeit insufficiently, over these past 80 years,” she said.
In a news conference on Monday in London, Callamard said that most governments tend to appease the “predators” rather than confront them.
“Some even thought to imitate the bullies and the looters,” she said.
Spain, however, which is an outlier in Europe for its criticism of Israel’s genocide against Palestinians in the Gaza Strip and US-Israeli attacks on Iran, “is standing above the double standard that is destroying the international system”, Callamard said.
She argued that Israel’s Prime Minister Benjamin Netanyahu, US President Donald Trump and Russia’s President Vladimir Putin, who in 2022 sent his forces into neighbouring Ukraine, have had an “absolutely dramatic” impact on the world.
Their conduct is “emboldening all of those that are tempted by similar behaviours,” said Callamard. “It is allowing for the multiplication of copycats around the world, and therefore what we are confronting now is much more aggressive and ferocious than what we had to confront three or four years ago.”
‘Authoritarian practices have intensified worldwide’
Amnesty’s review of the state of the world’s human rights makes for grim reading, documenting attacks on fundamental civil liberties in most nations.
“Authoritarian practices have intensified worldwide”, the report reads, before running through abuses alleged in countries from Afghanistan to Zimbabwe in 400 pages.
Israel’s genocide in Gaza, Russia’s “crimes against humanity” in Ukraine, and the US-Israeli war on Iran were noted as examples of conflict in which international laws have been ignored.
In a section on repression, the United Kingdom is blamed for cracking down on the Palestine solidarity movement and Palestine Action, the direct-action group that targets sites associated with the Israeli military and is currently fighting a legal battle against its UK proscription as a “terrorist” organisation.
Afghanistan’s Taliban was responsible for further gender-based discrimination in 2025, the report noted, citing measures excluding women from education and work, while Nepalese authorities were said to have failed to investigate instances of gender-based violence against Dalit women.
Amnesty’s report comes as multiple conflicts rage across the world.
The US-Israeli assault on Iran has killed more than 3,000 people, while Israeli attacks in Lebanon have killed nearly 2,400. In Gaza, the confirmed number of people killed in Israeli attacks since October 2023 has surpassed 72,500 as the decimated territory is continually threatened by Israeli bombardment. In Ukraine, more than 15,000 have been killed since Russia’s full-scale invasion began more than four years ago.
Conflicts in the Middle East are a “product of the descent into lawlessness, made possible by a vision of the world in which war-making and the killings of civilians are normalised”, said Callamard.
“No effective steps have been taken against Israel for its repeated, constant violation of basic standards of humanity.”
However, there is some room for optimism, Amnesty said.
It listed moments of “resistance” such as Gen Z-led protests; the growing number of states joining South Africa’s case against Israel’s genocide at the International Court of Justice (ICJ); the International Criminal Court’s (ICC) crimes against humanity charges against former Philippine President Rodrigo Duterte; the Council of Europe’s special tribunal for the crime of aggression against Ukraine; and the ICC’s arrest warrant against two Taliban leaders for “gender-based persecution”.
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