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San Francisco 49ers at Seattle Seahawks: Predictions, picks and odds for NFL Week 6 game

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1 year ago

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San Francisco 49ers at Seattle Seahawks: Predictions, picks and odds for NFL Week 6 game


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The NFL’s Week 6 will kick off with a “Thursday Night Football” matchup between two teams coming off head-scratching losses: the San Francisco 49ers (2-3) and Seattle Seahawks (3-2).

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Last week’s second half was one to forget for San Francisco. After leading the Arizona Cardinals by 13 at halftime, the 49ers failed to score in the final 30 minutes while the Cardinals stormed back to steal one on the road. Holding onto leads has been an issue for San Francisco, and something that’ll need to be fixed soon if it wants to contend.

Not many people expected Daniel Jones to survive the hostile Seattle crowd, but the New York Giants quarterback stepped up and delivered a surprising win in the Pacific Northwest. Seattle has now lost two-in-a-row, and in a middling NFC West, the Seahawks need a win to keep their lead.

PROP TALK: These are the best prop bets for NFL games this week 

Seahawks vs. 49ers odds, moneyline, over/under

The 49ers are favorites to defeat the Seahawks, according to BetMGM NFL odds. Looking to wager? Check out the best mobile sports betting apps offering NFL betting promos in 2024 including the ESPN BET app and Fanatics Sportsbook promo code.

  • Spread: 49ers (-3.5)
  • Moneyline: 49ers (-190); Seahawks (+155)
  • Over/under: 47.5

Not interested in this game? Our guide to NFL betting odds, picks and spreads has you covered with Sunday Night Football odds and Monday Night Football odds.

New to sports betting? USA TODAY readers can claim exclusive promos and bonus codes with the best online sportsbooks and sports betting sites.

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FEELING LUCKY? Here are the best parlay bets and odds for NFL games this week 

NFL Week 6 odds, predictions and picks

Seahawks vs. 49ers | Bears vs. Jaguars | Ravens vs. Commanders | Packers vs. Cardinals | Patriots vs. Texans | Saints vs. Buccaneers | Eagles vs. Browns | Titans vs. Colts | Broncos vs. Chargers | Raiders vs. Steelers | Panthers vs. Falcons | Cowboys vs. Lions | Giants vs. Bengals  | Jets vs. Bills

Lorenzo Reyes: 49ers 25, Seahawks 17

There is some concern over San Francisco’s recent issues finishing games, but the good news for the Niners is many of the issues cropped up because of self-inflicted errors. The 49ers are very talented and should be able to increase their discipline and focus. This could also serve as a wake-up call and might be a nice buy-low chance. And Seattle is too unreliable.

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Tyler Dragon: 49ers 25, Seahawks 20

Are the 49ers in the midst of a Super Bowl hangover? They had a two-score lead at home in the second half against Arizona last week and still managed to lose. San Francisco is underachieving at the moment. Seattle at 3-2 is the only team in the NFC West with a winning record. But the Seahawks have lost five consecutive games versus San Francisco.

Jordan Mendoza: 49ers 26, Seahawks 20

Two teams needing to turn the page, expect the defenses to hold up early before each offense breaks through. Even if it’s in Seattle, the 49ers have won two-straight at Lumen Field. Make it three-in-a-row to put a tie on top of the NFC West.

MOST VALUABLE BET: Who is the favorite to win NFL MVP in 2024? 



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San Francisco, CA

Man convicted in the deadly 2021 assault of a Thai grandfather in San Francisco avoids prison

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5 hours ago

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March 27, 2026

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Man convicted in the deadly 2021 assault of a Thai grandfather in San Francisco avoids prison


SAN FRANCISCO (AP) — The man convicted in the fatal 2021 attack of an older Thai man in San Francisco, which galvanized a movement against anti-Asian hate, will be able to avoid prison time, a judge ruled Thursday.

Antoine Watson, 25, was sentenced to eight years for manslaughter in the death of Vicha Ratanapakdee, 84. But, having already spent five years in jail awaiting trial, Watson received credit for time served, and San Francisco Superior Court Judge Linda Colfax said he could have the remaining three years suspended if he follows the rules of his probation.

Ratanapakdee’s daughter, Monthanus, expressed her family’s disappointment in a statement shared by Justice For Vicha, the foundation named for her father.

“We respect the court process. However, this is not about revenge — it is about accountability,” she said. “When consequences do not reflect the seriousness of the harm, it raises concerns about how we protect our seniors and public safety.”

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Vicha Ratanapakdee was out for his usual morning walk in the quiet neighborhood he lived in with his wife, daughter and her family when Watson charged at him and knocked him to the ground. Ratanapakdee never regained consciousness and died two days later.

Watson testified on the stand that he was in a haze of confusion and anger at the time of the unprovoked attack, according to KRON-TV. He said he lashed out and didn’t know that Ratanapakdee was Asian or older.

San Francisco Public Defender Mano Raju, whose office defended Watson, also said at his trial that the defendant is “fully remorseful for his mistake.”

The Office of the San Francisco Public Defender did not immediately respond to an email requesting comment on Watson’s sentencing.

Footage of the attack was captured on a neighbor’s security camera and spread across social media, prompting a surge in activism over a rise in anti-Asian crimes driven by the COVID-19 pandemic. Hundreds of people across several U.S. cities commemorated the anniversary of Ratanapakdee’s death in 2022, seeking justice for Asian Americans who have been harassed, assaulted and even killed in alarming numbers.

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Asians in America have long been subject to prejudice and discrimination, but the attacks escalated sharply after COVID-19 first appeared in late 2019 in Wuhan, China. More than 10,000 hate incidents against Asian Americans and Pacific Islanders were reported to the Stop AAPI Hate coalition from March 2020 through September 2021.

While the Ratanapakdee family asserts he was attacked because of his race, hate crime charges were not filed and the argument was not raised in trial. Prosecutors have said hate crimes are difficult to prove absent statements by the suspect.



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San Francisco, CA

Authors gathering in San Francisco to raise awareness and money for the National Kidney Foundation

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17 hours ago

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March 26, 2026

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Authors gathering in San Francisco to raise awareness and money for the National Kidney Foundation


A number of notable authors are set to take part in a special event in San Francisco this Sunday, celebrating a shared love of reading while shining a light on an often overlooked health issue. The National Kidney Foundation Authors Luncheon brings together writers and community members to support kidney health awareness and raise funds for critical programs.

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Yankees top Giants 7-0 as robot umpire debuts

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1 day ago

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March 26, 2026

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Yankees top Giants 7-0 as robot umpire debuts




/ AP

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Aaron Judge went hitless on opening day for the first time and struck out four times for the first time since September 2024, but the New York Yankees still produced plenty of offense and beat San Francisco 7-0 Wednesday night in the debut of Giants manager Tony Vitello as the major league season began.

José Caballero drove in the go-ahead run with an RBI single in a five-run second and also lost the first challenge taken to Major League Baseball’s so-called robot umpire, unsuccessfully appealing a strike by Logan Webb in the fourth.

Max Fried (1-0) allowed two hits in 6 1/3 innings to became just the fifth Yankees pitcher since 1969 with at least 6 1/3 shutout innings on opening day, joining Catfish Hunter (1977), Ron Guidry (1980), Rick Rhoden (1988) and David Cone (1996). New York won an opener with a shutout on the road for the first time since 1967.

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Webb (0-1) started the fourth inning with a 90.7 mph sinker on the upper, inner corner that was called a strike by Bill Miller, a major league umpire since 1997. Caballero tapped his helmet, and the 12 Hawk-Eye cameras of the Automated Ball-Strike System upheld Miller’s decision in a graphic shown on the Oracle Park scoreboard.

Caballero singled in the second and Ryan McMahon followed with a two-run single before Austin Wells’ single prompted a mound visit for Webb. Trent Grisham hit a two-run triple and was checked by medical staff after a hard slide into third.

Judge was booed before the game and during each at-bat as he began his 11th big league season. The California native had been pursued by the Giants during free agency in 2022 but he ultimately chose the Yankees’ $360 million, nine-year contract offer.

Webb, a 15-game winner last season making his fifth start on opening day, was tagged for six earned runs — seven in all — and nine hits over five innings.

The 47-year-old Vitello made the big jump from coaching the University of Tennessee.

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The teams resum3 the series Friday afternoon, with RHP Cam Schlittler starting for New York opposite lefty Robbie Ray.

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AP MLB: https://apnews.com/mlb

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