San Francisco, CA
More time with your pets? SF biotech company trying to create fountain of youth for dogs
SAN FRANCISCO (KGO) — All of us love our canines. However what if we bought to like them for for much longer than we do now? That is the mission of a veterinary medication firm in San Francisco.
For Celine Halioua, her love of animals has spanned a lifetime.
“I’ve had 15 cats, 4 canines, squirrels, I’ve a horse,” she mentioned.
However over the previous few years, she’s taken her fondness for canines to a complete different stage.
Again in 2020, Halioua based the San Francisco-based biotech firm Loyal.
VIDEO: World’s oldest canine ‘Pebbles’ dies at age 22
It is mission – to develop, typically drastically – the life expectancy of canines, giving them extra time with their house owners.
“The way in which to consider it’s pulling out the wholesome center years. These years the place your canine desires to go to the park, is bounding round – can we now have extra of these?” mentioned Halioua.
The thought behind it’s that canine house owners will be capable to give their animals a sequence of medicine, sort of like heartworm capsules, over the course of their lives.
These medicine will then work at a mobile stage to assist pets stay more healthy and longer.
Halioua’s workforce has raised over $65 million in enterprise capital.
MORE: Deserted canine reunited with proprietor who left heartbreaking word
And whereas it is nonetheless early days, preliminary trials have proven some encouraging outcomes.
Loyal hopes to get FDA approval for 2 medicine by 2025.
“It is one thing that’ll be given to the canine each three to 6 months that can launch a drug over time at a constant fee,” mentioned Halioua.
Nevertheless it’s not simply pets and their house owners who may gain advantage.
Sherri Franklin is the CEO of Muttville Senior Canine Rescue – a shelter that is labored with Loyal for a few of their research.
VIDEO: Bay Space no-kill animal rescue in danger for closing per their landlord Caltrans
She says if profitable, Halioua’s work may revolutionize the best way individuals undertake animals and probably assist get 1000’s extra canines rescued.
Shelters would have a greater understanding of a canine’s age and total well being.
“We will save extra animals if we may give adopters clear info. That will be an final sport changer for us,” Franklin mentioned.
Halioua hopes that is solely step one in her journey.
However she says one objective will at all times stay the identical, making her merchandise inexpensive to everybody.
“These aren’t going to be like wealthy individuals medicine. They will be broadly accessible, that I hope someday virtually each canine is on,” she mentioned.
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San Francisco, CA
San Francisco West Portal hardware store closing after nearly 9 decades
A hardware store in San Francisco’s West Portal is closing up shop after being in business for 88 years.
Papenhausen Hardware made the announcement, saying it no longer could afford to stay open.
Karl Aguilar walked into this hardware store 29 years ago as a San Francisco State University student looking for a job. But in 2018, Aguilar became a co-owner and thought he would retire there.
Aguilar said it wasn’t just one thing prompting the closure, but two fires and the pandemic took a big hit on his business. He estimates sales dropped about 30% in the first year of the pandemic.
“By the second year, we realized it was time to sell and all of the emotional side of it,” said Aguilar. “What can we do, all the questioning, the sleepless nights happened then.”
On Saturday, Papenhausen Hardware started its going out of business sale. Many of the shelves are now empty as customers come by to make their final trip to their local hardware store.
“We thought there would be an increase in business but it’s just been this crushing avalanche of nonstop business for four days now,” said Matt Rogers the co-owner Papenhausen Hardware. “So, it’s impressive. Touching too really.”
“It’s been overwhelming in a good way?” Aguilar added. “The community is deeply upset. They wish it wasn’t the case and people have come out of the woodwork trying to come up with ideas and find ways to keep us here but the financial reality is that we just can’t stay.”
After 88 years in the West Portal neighborhood, generations of families have relied on this store for basic hardware supplies.
Customers like Lee Bradley said the closing is a huge loss to the community.
“Terrible news really,” Bradley said. “Devastation. The convenience is the whole thing. It’s nice having a store, just down the block that you could little bits and bobs. Whatever you wanted.”
But as customers shopping habits have changed after the pandemic, Papenhausen isn’t the only one struggling to keep its doors open.
Aguilar hopes people realize how important community support is to keep small businesses open.
“The one thing people should take from this is whether it be a bookstore, or a coffee shop or maybe a fabric store that you love,” he said. “I guarantee you that they’re struggling. If you want to see them there, you can support them and every dollar makes a difference.”
Papenhausen Hardware is scheduled to close on December 31st but if they run out of inventory, the store could be closed earlier.
San Francisco, CA
San Francisco Developer Unveils Plans for New 22-Story Ocean Beach Project | KQED
While the developers claim that the proposed project “exceeds” AB 2011’s standards, the application is still under review to determine if it qualifies for the expedited approval process granted by the law.
Sider noted that the proposal “hasn’t yet been assessed for Code compliance, but we remain hopeful that the project will be thoughtfully designed and adhere to all regulations.” He added that the location “has always been an ideal spot for new housing.”
The original plan for a 50-story, 712-unit high-rise was met with fierce opposition from city planners, residents and Supervisor Joel Engardio, who represents the Sunset District, where the site is located.
Engardio called the initial proposal a “middle finger to the city” and dismissed it as a plan “no one would take seriously.”
Although the new proposal significantly reduces the building’s height, with only 22 stories, Engardio remains critical.
“Twenty-two stories is still far beyond what’s reasonable,” he said in an interview. “We need to stop dreaming up massive skyscrapers at the beach and focus on real housing that will meet the needs of real families.”
Engardio pointed out that the Coastal Commission will need to weigh in on the project and criticized the developers for not adhering to the Sunset District’s current zoning laws, which limit building heights to 10 stories.
“We need more housing for seniors and families in the Sunset and throughout San Francisco,” Engardio said. “But no one wants Ocean Beach to turn into Miami Beach.”
San Francisco, CA
Breed picks ex-Bloomberg staffer for Board of Supervisors seat
Sherrill registered with the Democratic Party in 2023 after identifying as “no party preference” since first registering in San Francisco in 2016.
He has longstanding connections to former New York City Mayor Michael Bloomberg, an ally and supporter of Breed. After college, Sherrill worked as an assistant for the New York deputy mayor for operations and later was promoted to senior policy advisor during Bloomberg’s tenure.
Bloomberg contributed more than $1 million to an independent expenditure committee supporting Breed’s failed reelection bid this year; likewise, she endorsed Bloomberg during his unsuccessful presidential run in 2020. The San Francisco mayor’s office of innovation is funded by Bloomberg Philanthropies, his charity.
Sherrill denied that political ties between Bloomberg and Breed were a factor in his appointment, saying both care deeply about building cities and hiring great talent.
Not all District 2 community leaders were convinced. Jason Pellegrini, a former human rights commissioner and District 2 resident, said he will support Sherrill’s success in office, for the sake of the district. However, he said, Breed’s choice carries the whiff of a political favor, and Sherrill wasn’t the most experienced pick on the short list of possibilities.
“I’m extremely disappointed in Mayor Breed, the daughter of San Francisco, as she’s leaving office,” Pellegrini said. “I feel this is a slap in the face not only to District 2 but to San Francisco.”
Patricia Vaughey, president of the Marina-Cow Hollow Neighbors & Merchants Association, was skeptical of Sherrill’s appointment and said she had not seen him at community meetings.
“Here we go again with someone who doesn’t know what the fuck they’re doing,” Vaughey said. Still, she said she will do her best to support him: “I have to work with whoever I have to work with.”
Through a spokesperson, Breed’s office said, “The mayor made the appointment based on her belief in Stephen’s qualifications and abilities, nothing else.”
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