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Boston Micro Fabrication Launches Spinout in San Diego – San Diego Business Journal

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Boston Micro Fabrication Launches Spinout in San Diego – San Diego Business Journal


SAN DIEGO – Precision micro-printing provider Boston Micro Fabrication (BMF) has launched San Diego-based BMF Biotechnology Inc., a spinout dedicated to making specialized chips through cultivated large-scale tissues in vitro, helping accelerate new drug and cosmetic development.

Jennifer Sun
Chief Scientific Officer
BMF Biotechnology Inc.

“BMF Biotechnology’s BioChips allow scientists to grow human-like tissues in a lab setting and because these chips mimic how substances would be processed inside the body, scientists can use them to test drugs and cosmetic products,” BMF Biotechnology Chief Scientific Officer Jennifer Sun told the Business Journal.

“These microfluidic chips are an organ-on-a-chip platform, which can replicate the physiological conditions found in the human body by controlling the flow of small amounts of fluid through micro-size channels.”

Founded in 2016, BMF says it supports more than 2,000 customers globally with offices in Boston, China, Japan and now in San Diego.

“BMF has raised over $80M in investment funding, including $24M in 2023,” added Sun. “We have over 250 employees worldwide with global revenue growth exceeding 30% in 2023.”

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Wanting to be housed in San Diego’s vibrant biotech ecosystem, the company’s San Diego Research Institute was born in 2022. The newly launched biotech division will operate out of Carroll Canyon with ten or so employees to start.

Preliminary feedback has yielded promising results, says BMF.

“Specifically, significant progress has been made in terms of developing functional prototypes of the BMF Biotechnology’s BioChip, validating their efficacy in replicating human tissue models accurately,” shared Sun. “Furthermore, preliminary tests have shown encouraging outcomes of disease modeling and validating human drug responses.”

BMF is entering an arena of competitors like MIMETAS and InSphero – working to commercialize organ-on-a-chip technology. Sun says its product stands apart.

“Our BioChip platform offers distinctive features, including a micro-channel network designed to mimic blood vessels with micron level three dimensional features. This network ensures efficient nutrient delivery and waste removal throughout the chip, enabling the comprehensive replication of human tissues on a large scale.”

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Hybrid Printing Solution

In recent years, micro molding and 3D printing innovations have swept the micro-manufacturing world, advancing how production companies do business.

New England-based BMF’s core tech enables highly precise, micro-scale 3D printing across industries like healthcare, life sciences, electronics and machining.

“3D printing has often been known for its ability to rapidly iterate on product design, but this same benefit can also be applied to developing custom, high-precision solutions that advance research in other ways – such as through pharmaceutical development,” said Sun. Now the industry is trending toward miniaturization. “As products and technology get smaller, the connective parts become micro and more intricate. There is an urgent need for highly precise and accurate manufacturing methods that allow engineers and product designers to consistently create small-scale parts with the precision, resolution and accuracy needed to move industries forward.”

This month, BMF announced what it calls the industry’s first line of hybrid printing solutions for micro-scale and ultra high-resolution applications that allow the user to print two resolutions within a single layer or in different layers.

John Kawola
CEO-Global
BMF

“Our driving motivation for innovation has been to offer new platforms that can help realize high-value applications for 3D printing,” said BMF CEO-Global John Kawola. “Increasingly, we have been pushed by our customers to bring our technology to applications where higher precision and tighter tolerances would result in an overall increase in quality and performance, regardless of part size.”

It comes after another big win for the company. Last year it launched what it deems the world’s thinnest cosmetic dental veneer, UltraThineer™. This April, BMF secured FDA 510(k) clearance on the material.

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“As we think about the future for BMF Biotechnology, we anticipate expanding our product portfolio to address a wider range of therapeutic areas and applications, revolutionizing the way drugs are developed and tested,” Sun added. “Our goal is to be a globally recognized leader in organ-on-a-chip technology, driving transformative advancements in drug discovery, cosmetic development, toxicity testing, and personalized medicine to improve human health and safety.”

Boston Micro Fabrication
FOUNDED: 2016 in Boston, San Diego Research Institute in 2022
CEO: John Kawola
LOCAL DIVISION HQ: San Diego
EMPLOYEES: 10 in San Diego; 200+ globally
BUSINESS: biotech
CAPITAL RAISED: $80 million
WEBSITE: bmf3d.com
CONTACT: info@bmf3d.com
NOTABLE: BMF was named one of the Boston Business Journal’s “Fast 50” companies, an annual honor recognizing the 50 fastest-growing private companies in Massachusetts.



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San Diego health officials monitor hantavirus situation as cruise ship passengers return to U.S.

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San Diego health officials monitor hantavirus situation as cruise ship passengers return to U.S.


SAN DIEGO (KGTV) — American passengers from a cruise ship hit with a hantavirus outbreak are back in the United States.

San Diego County health officials say they are monitoring the situation and there is no need for panic.

“The risk to Californians is really low and especially here in San Diego. Since the year 2000, we’ve only had 4 cases of hantavirus and the majority of those were in travel related cases so not even acquired here locally,” Ankita Kadakia, deputy public health officer for the County of San Diego, said.

According to the CDC, hantavirus is spread through contact with infected rodents.

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“The virus can be in their saliva, feces or droppings,” Kadakia said.

San Diego County does see cases of rodents infected with hantavirus, but the strain seen locally is not the same strain connected to the cruise ship outbreak.

“The vast majority of strains of hantavirus are mouse or animal to human transmission. Not human to human transmission. So the Andes strain, which is found in Argentina, there is evidence that there is human to human transmission,” Dr. Ahmed Salem, a pulmonologist at Sharp Memorial Hospital, said.

Salem treated hantavirus during the 2012 Yosemite National Park outbreak.

“One of the ways you die from hantavirus is you get a collapse of your cardiac system and your pulmonary system and you have to go on something called ECMO. It’s one of the most aggressive forms of life support that you can do. So I do remember that case, and unfortunately, that person passed away,” Salem said.

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There is currently no cure or vaccine for hantavirus. Health officials stress that for those who were not on the cruise ship, the risk of contracting the virus remains low.

This story was reported on-air by a journalist and has been converted to this platform with the assistance of AI. Our editorial team verifies all reporting on all platforms for fairness and accuracy.





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Machado's walk-off lifts Padres to 10-inning comeback victory over Cards

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Machado's walk-off lifts Padres to 10-inning comeback victory over Cards


SAN DIEGO — The Padres earned a split against the Cardinals in dramatic fashion on Sunday afternoon. Nick Castellanos hit a game-tying two-run homer in the bottom of the ninth, and Manny Machado’s sacrifice fly won it in the 10th.
Here’s some instant reaction from the Padres’ wild 3-2 victory



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Padres come back, walk off with win over Cardinals to split series

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Padres come back, walk off with win over Cardinals to split series


It seemed like the same tired story.

Instead, it was the same thriller.

The Padres pushed their offensive lethargy as long as possible without paying for it Sunday, tying the game with two outs in the ninth inning on Nick Castellanos’ two-run homer and then celebrating after Manny Machado’s sacrifice fly in the 10th inning gave them a 3-2 victory over the Cardinals.

“Getting it done,” Machado said.

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That’s it. That is all they are doing.

And at what is essentially the quarter mark of the season, the Padres are 24-16 and tied with the Dodgers atop the National League West.

The shocking component of their having the major leagues’ fifth-best record is that the Padres rank in the bottom three among MLB’s 30 teams in batting average and OPS.

They split with the Cardinals despite having 14 hits, their fewest in a four-game series in franchise history. Their 61 hits over their past 10 games are the fewest in a stretch that long since 2019, and they are 5-5 in those games.

“It sucks; we need to hit; Machado said. “I mean, you know, look, it’s obvious. We’re not hitting. It’s obvious, but we’re getting things done, man.”

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Nick Castellanos #21 of the San Diego Padres watches his two-run home run in the ninth inning against the St. Louis Cardinals at Petco Park on May 10, 2026 in San Diego, CA. (K.C. Alfred / The San Diego Union-Tribune)

Sunday was the Padres’ 12th victory this season in which the decisive run was scored in the seventh inning or later. That is exactly half their victories.

It was their fourth walk-off victory, their second in extra innings. It was the seventh time that a run scored in their final offensive half-inning decided a victory.

So it is no small thing to proffer that Sunday was possibly their most dramatic triumph. Because it was possibly their most unlikely one.

Not only were they a strike away from defeat, but they began the ninth inning having gotten two hits all day.

The Cardinals took a 2-0 lead in the fourth inning on their first two hits off Walker Buehler — a single by Alec Burleson and a home run by Jordan Walker with two outs. Buehler pitched six innings, allowing just one more hit before Ron Marinaccio worked two scoreless innings.

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But the Padres were unable to make anything of their seven at-bats with runners in scoring position over the first eight innings. They had walked five times but had just Jackson Merrill’s third-inning single and Xander Bogaerts’ fourth-inning double to that point.

“Really good teams find ways to win games when they’re not doing their best,” Gavin Sheets said. “… We’re not clicking on all cylinders by any means. And I don’t think any of us would say that he’s on a roll right now, but we’re getting hits in a timely fashion and it’s someone different every night.”

Almost.

The Padres have game-winning RBIs from 10 different players. They have go-ahead RBIs from 13 of the 14 position players who have been on their roster this season. Sunday was Castellanos’s third game-tying RBI.

His home run, on the ninth pitch of his at-bat against Cardinals closer Riley O’Brien, was something of a clinic by a veteran hitter who is in his first season as a role player.

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Castellenos, who entered the game as a pinch-hitter in the seventh inning and remained in right field, came to the plate with Bogaerts at first base with two outs.

Bogaerts’ single leading off the inning had been followed by two strikeouts, and Castellanos fell behind 0-2 before working the count full and then sending a 99 mph sinker on the inner edge of the plate almost to the ribbon scoreboard fronting the second level of seats beyond left field.

“The first pitch started, and I was probably looking to do what I did,” he said. “And then I ended up getting 0-2 and chasing. After that, just took a deep breath and tried to shorten up as much as possible and just compete. Just find a way on base. And then found myself in a full account and was able to get the job done.”

It was the first home run allowed by O’Brien this season.

Nick Castellanos #21 of the San Diego Padres is dunked by Gavin Sheets #30 after a 3-2 win against the St. Louis Cardinals at Petco Park on May 10, 2026 in San Diego, CA. (K.C. Alfred / The San Diego Union-Tribune)
Nick Castellanos #21 of the San Diego Padres is dunked by Gavin Sheets #30 after a 3-2 win against the St. Louis Cardinals at Petco Park on May 10, 2026 in San Diego, CA. (K.C. Alfred / The San Diego Union-Tribune)

With closer Mason Miller not available after throwing 29 pitches over 1⅓ innings on Saturday, Jeremiah Estrada got the first two outs of the 10th. With runners on first and second, Adrian Morejón entered the game and got an inning-ending pop out on his first pitch.

Gordon Graceffo was on the mound for the Cardinals, and Ramón Laureano was the Padres’ automatic runner in the 10th. The Cardinals intentionally walked Merrill at the start before Fernando Tatis Jr. whittled a 1-2 count into a walk to load the bases.

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The game was over one pitch later, when Machado sent a fastball to right-center field and Laureano slid across the plate well in front of right fielder Jordan Walker’s throw.

It was a somewhat subdued but still enthusiastic celebration along the first-base line, as teammates bounced around Machado.

“It’s hard to win a game like that,” Padres manager Craig Stammen said. “Their pitchers pitched great, and they’re bringing in one of the best closers in the game. And we just stuck with it. It just speaks to how those guys believe in themselves and how they believe in what we’ve got going on as a team.”



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