A driver who led officers on a pursuit through Santa Monica and into West Los Angeles Friday morning was taken into custody after crashing head-on into multiple vehicles on the 405 Freeway.

Sky5 was over the pursuit on Santa Monica Boulevard shortly after 5 a.m. where the driver was being followed by officers.

Video showed the driver attempting to ram patrol vehicles and then leaning out the window of the van and shouting at officers.

At one point the van turned around and chased one of the patrol vehicles down the street in an attempt to crash into it.

“This is nuts. She’s chasing a black and white. She’s got a couple of other cars behind her … Look at this. This is just craziness,” Sky5 reporter Mike Case said.

Police have not confirmed if the suspect is male or female but said the driver was wanted for assault with a deadly weapon.

Police attempted several pit maneuvers on the northbound 405 Freeway but were unsuccessful.

The driver then began driving in the wrong direction on the freeway and crashed head-on into another vehicle but that still did not stop the van.

The driver continued on and drove at full speed, and again slammed head-on into multiple vehicles that were stopped on the freeway.

The collision left at least one vehicle badly damaged and caused the van to finally become disabled.

The suspect exited the van, climbed on top of a big rig and sat on the hood until being taken into custody by officers.

At least two officers were injured and hospitalized in unknown condition during the incident.

It was unclear how many motorists were injured in the collisions.

Check back for updates on this developing story.