Science
What to Know About the Hepatitis A Outbreak in L.A. County
Public health officials in Los Angeles County have declared an outbreak of hepatitis A, a highly contagious liver infection driven by a virus that can, in rare cases, cause severe illness.
The condition, which is typically identified in fewer than 50 people in L.A. County each year, infected at least 138 people in 2024 and cases have remained unusually high so far in 2025. Officials say that levels of the virus in local wastewater suggest these figures are an undercount.
Here’s what to know.
How is hepatitis A transmitted?
The hepatitis A virus is spread through the so-called oral-fecal route, which means it is ingested through food or drinks that have been contaminated by microscopic bits of stool from an infected person. It can also spread through close contact with someone who is carrying the virus, even if they don’t show any symptoms.
Unhoused people are often at greater risk of contracting hepatitis A because they have limited access to proper toilets and hand-washing facilities. The virus is also more common among travelers to places with poor sanitation, men who have sex with men and people who use drugs.
But officials say many of the recent cases have occurred in people without those risk factors. They do not yet know why, but Dr. Timothy Brewer, an infectious disease physician and epidemiologist at U.C.L.A., said it had led him to worry about two things: food contamination, and community circulation.
“If you’re practicing good hygiene in a community that has access to potable water, you really should not be seeing a lot of this,” he said. “Something is going on — but exactly what that something is, we don’t yet know.”
What are the symptoms of a hepatitis A infection?
The first signs of the infection can look a lot like a classic stomach bug: fever, fatigue, nausea and a loss of appetite, followed by vomiting and diarrhea. Over time, people who become infected can also experience yellowed skin and eyes, dark urine and pale stools.
One of the challenges to halting a hepatitis A outbreak is that contact tracing can be nearly impossible. The infection can incubate for up to seven weeks before symptoms appear, and a person carrying the virus can spread it for up to two weeks before they feel ill.
In addition, a significant proportion of people who become infected don’t experience major symptoms, said Dr. Edward Jones-Lopez, an infectious disease specialist with Keck Medicine of the University of Southern California, so they do not visit their doctor, who in turn does not run a blood test and report the case.
Severe symptoms are most often seen in older adults, people with chronic liver conditions, and those with weakened immune systems or H.I.V. On rare occasions, a hepatitis A infection can be fatal. In this outbreak, at least seven people have died. That may seem like an unusually high fatality rate, but officials believe far more people have been infected than the official numbers show. Most have probably been asymptomatic, or shown symptoms mild enough to have been misidentified.
How is hepatitis A treated?
There is no specific antiviral medication for hepatitis A. The infection usually resolves on its own within a few weeks, and most people do not face lasting liver damage. But for some, hospitalization can be necessary.
In rare cases, the infection can devolve into an acute liver failure called fulminant hepatitis, which may require a transplant, said Dr. Jones-Lopez. “It can progress very, very quickly — that’s a very serious disease.”
If you think you might be infected, be sure to visit your doctor, drink lots of fluids, and get adequate rest.
How can I avoid it?
The best way to prevent a hepatitis A infection is through vaccination. The regimen — two doses of vaccine, at least six months apart — provides protection for life. It has been routinely given to children for the last two decades, but many adults 25 and older have not gotten the shots unless they were in a high-risk group.
The fact that the outbreak is occurring outside of traditional populations “underscores the need to reassess how — and where — we target prevention efforts,” said Dr. Anne Rimoin, an epidemiology professor at U.C.L.A., since “an infection anywhere is potentially an infection everywhere.”
If you are unvaccinated but know you have been exposed to a person carrying the virus, a prompt vaccination can prevent your becoming infected. Experts say that some people with weakened immune systems who are exposed could also benefit from receiving immune globulin as well. And good hygiene is a wise protective measure for everyone; wash your hands with soap and water, especially after using the bathroom, and before preparing food.
Science
Record Heat Meets a Major Snow Drought Across the West
At this point in a typical year, as the seasons officially turn from winter to spring, snowpack would still be accumulating across the Mountain West.
But this winter wasn’t typical, even before a heat wave this past week. It was the warmest on record for six Western states. Snow cover is the lowest level on record for the Colorado River Basin, and across much of the rest of the West, there are record or near-record low amounts of snow.
That alone would create a challenging year for water managers, who rely on slow and steady snowmelt to feed streams, rivers and reservoirs and meet spring and summer demand for irrigation and drinking water. While rainfall runs off quickly and can more readily evaporate from soil, snowpack serves as a valuable and lasting source of moisture and accounts for a majority of water supplies across the region, as much as 80 percent in some areas.
Current snowpack compared to historical averages
The intense heat wave threatens to make water management all the more challenging.
Much of the thin snowpack was already “ready to melt” before the heat set in, said Jon Meyer, assistant state climatologist at the Utah Climate Center. “This is the nail in the coffin.”
It’s unusual to see the whole West like this, said Leanne Lestak, an associate senior scientist at the University of Colorado Boulder who specializes in mapping snow and how much water it holds.
In early March, Ms. Lestak and her team found that vast majority of the Western United States had less than two-thirds of the amount of snow typical for this time of year, with few exceptions. In Arizona and parts of Nevada, New Mexico and Oregon, snowpack was less than a quarter of what it would usually be.
“The situation is pretty dire,” Dr. Meyer said.
The heat wave is also increasing the already-elevated fire risk across some drought-stricken areas. In Nebraska, drought set the stage for the largest wildfire in state history, which broke out last week and has not yet been contained.
The conditions that led to this year’s low snowpack are unusual, too. Snow droughts often develop from dry weather patterns that starve the West of any significant precipitation during the winter, said Dan McEvoy, a climatologist at the Desert Research Institute and Western Regional Climate Center.
But in many places, it wasn’t necessarily a dry year, he said. Instead, temperatures have been so warm that precipitation has fallen as rain, rather than snow, even at higher elevations.
Many of the mountaintops could still see some more snowfall. But as Cody Moser, a hydrologist with the Colorado Basin River Forecast Center in Salt Lake City, looks ahead to predicting how the spring will go, he doesn’t foresee any significant change in weather patterns. Now he’s expecting peak snowmelt flows to occur earlier than ever recorded in many locations, he said this week.
“I think it’s highly likely we’ve seen peak snowpack,” Mr. Moser said.
Snowpack feeding the Colorado River reaches historic lows
Even after a winter that was the warmest on record for Arizona, New Mexico, Colorado, Utah, Wyoming and Oregon, the heat that set in across much of the West this past week was extreme. Meteorologists said they were expecting to set record highs for the month of March in many locations, and the earliest arrivals of 100-degree temperatures in records that go back more than a century.
Across the Colorado River Basin, even at elevations as high as 10,000 feet, temperatures were forecast to surge into the 50s and 60s Fahrenheit on Friday and Saturday, Mr. Moser said, some 15 to 20 degrees warmer than average.
Relatively light winds and dry air over the region could limit snowmelt to some degree, he said, but the warmth and sunshine may prevent some moisture from ever reaching stream beds, said John Fleck, a water policy expert at the University of New Mexico.
“A lot of it is going to evaporate off before it even has a chance to hit the stream,” Mr. Fleck said.
This heat wave is so extreme that it would only be expected to occur once about every 500 years in the current climate, according to World Weather Attribution, a group of scientists who study links between extreme weather events and climate change.
“These temperatures are completely off the scale for March, and our data shows that they would be virtually impossible in a world without human-caused climate change,” said Ben Clarke, a research associate in extreme weather and climate change at Imperial College London.
In places like the Colorado Front Range, home to the majority of that state’s population, snowpack serves as the largest source of water. For the utility Denver Water, snowpack usually contains significantly more water than its largest surface reservoir, said Taylor Winchell, the agency’s climate adaptation program lead.
Denver Water has enough supply to handle a low-water year, but the snowpack conditions are creating “very high levels of concern,” Mr. Winchell said. The Denver Water Board is poised to officially declare Stage One drought restrictions, asking residents to significantly reduce their outdoor watering. If the snow drought were to repeat for multiple years, the problem could compound and worsen, he said.
The snow drought occurs at a critical time for the larger Colorado River Basin. An agreement among the basin’s seven states over how to divide its water expired at the end of last year, and negotiations to develop a new water plan fell apart last month. (The states are also obligated to share a small portion of the water with Mexico.)
The snow drought is complicating that work. Snowpack from the river’s Upper Basin, across mountains of Colorado, Utah, New Mexico and Wyoming, accounts for a majority of the river’s natural flow each year. Declining spring precipitation and rising temperatures have caused the Colorado’s flow to decrease by nearly 20 percent over the past quarter century.
Recent forecasts estimated that inflows to Lake Powell, a key reservoir that straddles the Utah-Arizona border, will be the third-smallest on record. The lake’s surface could drop to a critical level for hydroelectric power production by the end of this year, affecting a power grid that serves seven states.
Officials at the Bureau of Reclamation, the federal agency that oversees the Colorado River and its reservoirs, declined to be interviewed but said in a statement they were monitoring hydrologic conditions to guide decisions about how to manage the Colorado River system.
Mr. Fleck said a crisis without precedent could be brewing. While a drought that hit the basin in 2002 was worse, it was relatively more manageable than what the West now faces: “We’re having one of the worst years in many decades, but with no cushion of reservoir storage to fall back on to bail us out.”
Science
New report on L.A. post-fire beach contamination finds something unexpected: good news
Researchers investigating the long-term effects of the 2025 firestorms on L.A.’s beaches have found that rarest of things: good news.
In the year following the Palisades and Eaton fires, levels of harmful metals like lead in coastal sand and seawater have remained far below California’s limits for safe drinking water and the U.S. Environmental Protection Agency’s safety thresholds for aquatic life.
“We’re not seeing any evidence for harm in the ecosystem or harm for human health,” said Noelle Held, a University of Southern California marine biogeochemist and principal investigator for the CLEAN Waters project, which is measuring post-fire water quality.
The Palisades and Eaton fires burned more than 40,000 acres and destroyed at least 12,000 buildings, blanketing the ocean in ash for up to 100 miles offshore. Heavy rains a few weeks later washed the charred remnants of plastics, batteries, cars, chemicals and other potentially toxic material into the sea and up onto beaches via the region’s massive network of storm drains and concrete-lined rivers.
Initial testing by the nonprofit environmental group Heal the Bay in the weeks after the fires documented a spike in lead, mercury and other heavy metals in coastal waters. Concentrations of beryllium, copper, chromium, nickel and lead in particular were significantly above established safety thresholds for marine life, prompting fears for the long-term health of fish, marine mammals and the marine food chain.
For their most recent study, Held’s team analyzed seawater samples collected along multiple locations on five different dates between Feb. 10 and Oct. 17 in 2025, along with sand collected in August.
Seawater lead concentrations were highest in the month after the fire and in October, when the season’s first major rain had just washed months’ worth of urban pollution into the ocean.
Even at their peak, lead levels barely surpassed 1 microgram per liter — well below the U.S. Environmental Protection Agency’s aquatic life safety threshold of 8.1 micrograms per liter.
While levels of iron, manganese and cobalt were higher in sampling locations near the Palisades burn scar than they were in other areas, even there they remain well below concentrations that could pose harm to human or marine life.
For beach sand collected in August, lead levels never topped 14 parts per million at any location, significantly below both the current California residential soil standard of 80 parts per million and the stricter 55 parts per million standard proposed by environmental health researchers.
“This isn’t something we would flag if we were testing your soil in your yard,” Held said.
The recent findings are consistent with water quality tests the State Water Resources Control Board conducted earlier in 2025. A board spokesperson said those found both higher relative concentrations of metals closest to the burn scars and no overall evidence that post-fire pollution poses an ongoing threat to human health.
Yet the need for continued testing remains. Officials struggled to answer questions about post-fire beach safety in part because of a lack of historical data on pollution levels, a pitfall researchers would like to forestall before another disaster arrives.
Future rainstorms could also continue to wash metals into Will Rogers Beach and the Rustic Creek outfall, both of which are near the Palisades burn scar, CLEAN Waters warned.
“Post-fire impacts can change over time, depending on rainfalls, runoffs and sediment movements,” said Eugenia Ermacora, manager of the nonprofit Surfrider Foundation’s L.A. chapter, which has partnered with Held’s team to collect samples. “It’s not just about the fires, but it’s about urbanization and how much our city needs to continue the work of doing testing in the water.”
Science
Freaked out by the news? Tips for staying calm from ex-refugees, hostages and ‘uncertainty experts’
War in Iran. Sleeper cells. Soaring gas prices. A new virus. ICE arrests. The acceleration of AI. And a rogue food delivery robot. Is your heart racing yet?
Amid one of the highest-stakes, most chaotic news cycles in recent memory, it’s hard to keep calm while scrolling through the day’s doom-saturated headlines.
Fear not. A team of British scientists, two authors and a group of thought leaders once deemed societal outcasts are here to help. Sam Conniff and Katherine Templar-Lewis’ new book, “The Uncertainty Toolkit: Worry Less and Do More by Learning to Cope With the Unknown,” presents evidence-based strategies to help you not only tolerate uncertainty, but thrive in the face of it.
Conniff, a self-described author and “social entrepreneur,” and Templar-Lewis, a neuroscientist, partnered with the University College London’s Centre for the Study of Decision-Making Uncertainty as well as real world “uncertainty experts” — former prisoners, drug addicts, hostages, refugees and others — to execute the most extensive study to date on “Uncertainty Tolerance,” which published in 2022. Their web project, “Uncertainty Experts,” is an interactive “self development experience” that includes workshops and an online Netflix-produced documentary, through which viewers can test their own uncertainty tolerance.
Their “Uncertainty Toolkit” book, out April 7, addresses the three emotional states that uncertainty puts us in — Fear, Fog and Stasis — while blending personal stories from the subjects they interviewed with the latest science on uncertainty, interactive exercises and guided reflections.
“The Uncertainty Toolkit” aims to help you keep calm amid chaos.
(Bluebird / Pan Macmillan)
“We are scientifically in the most uncertain times,” Templar-Lewis says. “There’s something called the World Uncertainty Index, which charts uncertainty [globally]. And it’s spiking. People say life has always been uncertain, and of course it has; but because of the way we’re connected and on digital platforms and our lives are so busy, we’re interacting with more and more moments of uncertainty than ever before.”
We asked the authors to relay three strategies for staying calm in challenging times, as told to them by their uncertainty experts.
This interview has been edited for length and clarity.
Advice from an ex-addict: Be grateful: Morgan Godvin is an ex-addict and human rights activist from Oregon who served four years of a five-year sentence in a federal prison, Conniff says.
“She developed a practice of ‘Radical Gratitude.’ Even in a world that feels so overwhelming, we can all find an object from which to derive a sense of gratitude,” he says. “As an emotion, gratitude provides a counterweight to anxiety that is almost as powerful as breath work or any of the other [anti-anxiety] well-known interventions.”
In prison, Godvin — who suffers from anxiety — created a daily practice to help her cope. “She began being grateful for the blankets, the only thing she had — and they were threadbare blankets,” Conniff says. “And by digging deep and really emphasizing the warm sensation we know of as gratitude, it became a biological hack. When the body starts to feel grateful, the hormones the body releases brings it back into what’s known as homeostasis or a sense of equilibrium; it activates the parasympathetic nervous system. It’s a very humbling and very healthy practice when the world’s just too much.”
Advice from a survivor of suicidal depression: Lean into the unknown. Vivienne Ming is a leading neuroscientist based in the Bay Area who faced a web of personal challenges in her early 20s. Ming, who was assigned male at birth, dropped out of the Massachusetts Institute of Technology, became homeless and was “living out of their car with a gun on their dashboard,” Conniff says. “They faced homelessness and near suicidal depression before finding a path that took them through gender transition to a place of real identity, marriage, family and success as a scientist.”
How? They developed and cultivated an awareness of “negativity bias,” Conniff says. “We all have a predetermined negativity bias. And in times of uncertainty, that negativity bias goes off the charts and we start to limit ourselves and shut ourselves down. By understanding this, we begin to be able to make a choice: Am I shutting myself down to the opportunities of life? Am I not getting back to people? Am I not taking the chances that are presented to me?”
What’s more, uncertainty, Dr. Ming pointed out, is actually good for you. It unlocks parts of your brain.
“Uncertainty drives neuroplasticity, our ability to learn,” Conniff says. “So [it’s about] resisting negativity bias — that this is all dangerous and difficult and we’re told not to trust each other — and instead, Dr. Ming’s response is to lean into the unknown. She says ‘the best way forward is to all walk slowly into the deep end of our own lives.’”
Advice from an ex-refugee: Reflect on your gut. Rez Gardi grew up in a refugee camp in Pakistan, before her family relocated to New Zealand. She’s now a lawyer and human rights activist working in Iraq.
“Rez correctly identified the scientific explanation for what we all call ‘gut instinct,’” Conniff says. “It’s known as ‘embodied cognition.’ The idea is that we have two brains — the gut instinct is an incredibly complex system of data points and it literally is in our gut and it’s connected to our brains via the vagus nerve. What it does is it brings your intuition in line with your intellect.”
So how to tap into it? “Rez talked about reflecting on her gut instinct,” Conniff says. “So when you have a feeling that you are right or wrong, go back to that feeling: What color was it? What shape was it? Where was it in your body? What temperature was it? Rez honed her gut instinct to become incredibly accurate: Should she trust this person? Was she safe? And that gut instinct became a highly tuned instrument. When we are trying to solve problems, when we are trying to communicate, these signals are as accurate as the best of our cognitive problem-solving abilities.”
Conniff and Templar-Lewis spoke to nearly 40 uncertainty experts in all. And with all of them, Conniff adds, “they kind of learned these techniques themselves, but the scientific evidence really backs it up.”
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