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Nations Should Conserve Fuel as Global Energy Crisis Looms, Agency Warns

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The struggle in Ukraine is setting into movement the primary international power disaster of its type, and nations around the globe ought to reply by lowering their use of oil and fuel, the chief of a key worldwide group warned on Friday.

The Worldwide Vitality Company, which was fashioned within the wake of the 1973 oil disaster to make sure a steady worldwide power market, stated that the repercussions of Russia’s invasion of Ukraine have been more likely to intensify over the following a number of months as summer time driving season obtained underway with inventories at historic lows.

“Decreasing demand is a manner of addressing the state of affairs with out simply pumping extra oil,” stated Fatih Birol, the company’s govt director.

It’s a message that has largely been absent from the dialog in the US, the world’s largest oil producer, the place fossil gas corporations are incomes wholesome income and the response to elevated gasoline costs has been requires extra manufacturing.

Dr. Birol stated that the power crunch was more likely to intensify and that it differed from the 1973 oil scarcity as a result of it entails not simply oil however pure fuel — which impacts transportation and electrical energy — and since nations are extra interconnected now, with the outcome {that a} disturbance in a single provide can have a larger impression on international markets.

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On Friday, the company really helpful 10 speedy steps that nations might take to preserve oil, corresponding to lowering velocity limits, having individuals make money working from home as much as three days per week and urging vacationers to take trains as an alternative of airplanes when doable. The really helpful measures additionally embody car-free Sundays in cities, automotive pooling and lowering fares on public transportation.

If superior economies put all 10 suggestions into motion, they may minimize oil demand by 2.7 million barrels a day, the company discovered. That’s on par with the estimated 2.5 million barrels a day of Russian oil that’s anticipated to be misplaced to international markets within the subsequent few months as patrons shun it. The company additionally urged a collection of structural, longer-term modifications, together with electrical warmth pumps and prioritizing of electrical automobiles.

Within the European Union, which in recent times has gotten about 40 p.c of its pure fuel and greater than 1 / 4 of its crude oil from Russia, leaders have been encouraging residents to preserve power. “Everybody can do one thing,” Ursula von der Leyen, the president of the European Union’s govt arm, stated in a information convention final week. “Decreasing the power consumption we have now general, the person contribution by 450 million Europeans, makes an enormous chunk.”

In the US, one of many few requires conservation has come from Mitch Roth, the mayor of the County of Hawaii, which is especially susceptible to skyrocketing power costs within the wake of President Biden’s banning of Russian oil, fuel and coal. The state of Hawaii has relied closely on Russian gas, and its excessive value of dwelling has many households already struggling to pay their payments. So Mr. Roth turned to what he noticed as a standard sense answer: asking his group to make use of much less oil and fuel.

“We’re not mandating something,” stated Mr. Roth, who has jurisdiction over the island of Hawaii, often called the Large Island. “However for the betterment of your checkbook, for the betterment of our group, for the betterment of our nation and for the betterment of our world, it makes a whole lot of sense.”

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Mr. Biden has urged oil corporations to step up manufacturing to maintain up with demand, and his power secretary, Jennifer Granholm, delivered the message personally to fossil gas executives gathered in Houston final week. Mr. Biden criticized corporations this week over the sluggish decline in costs on the pump whilst the value of oil has eased.

In the long run, administration officers keep, the US should make a transition away from fossil fuels and develop extra photo voltaic, wind and different clear power sources.

“We all know we can not drill our manner out of dependence on a worldwide commodity managed partly by international nations and their leaders, which is why the administration is set to hurry up — not decelerate — our transition to a clear power future,” stated Charisma Troiano, a spokeswoman for Ms. Granholm.

Clear power is the final word answer to tackling international warming and lowering power dependency on different nations, many consultants say. However it may’t come on-line quick sufficient to fulfill speedy demand. To make issues worse, nations have been already far behind on the emissions reductions wanted to fulfill the Paris Settlement, a worldwide pledge meant to keep away from the worst results of local weather change.

Whereas Western nations attempt to take care of the humanitarian disaster and the power issues ensuing from the struggle in Ukraine, “we must always not overlook a 3rd disaster, which is the local weather disaster,” Dr. Birol of the Worldwide Vitality Company stated. “And consequently, the entire 10 measures we placed on the desk not solely tackle the crude oil market tightness, but additionally assist to pave the best way to succeed in our local weather targets.”

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A White Home spokesman declined to remark about whether or not Mr. Biden deliberate to name on Individuals to preserve power, one thing perceived as carrying political dangers.

A handful of Democrats in Congress have talked about conservation. “We have to discuss reducing demand,” stated Consultant Kathy Castor, Democrat of Florida. “If we decrease demand, that actually saps the facility of those petro despots to regulate our lives.”

Kathleen Sgamma, president of the Western Vitality Alliance, which represents oil and fuel corporations, stated she related conserving power with deprivation.

“I imply, we by no means need individuals to be wasteful with power,” she stated in an interview. “However do you wish to inform the American those that they will’t drive to high school and work and never warmth their properties? I imply, the whole lot in your desk is the results of oil and pure fuel.”

Mr. Biden would face a sure backlash if he known as for Individuals to preserve power — significantly because the nation is rising from the coronavirus pandemic, stated Lee M. Miringoff, director of the Marist Faculty Institute for Public Opinion.

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“Individuals are changing into turned off to the entire notion of masks, so the message of private sacrifice — having to change their habits not directly — will get right into a freedom dialogue that the White Home doesn’t wish to go close to proper now,” Dr. Miringoff stated.

With midterm elections looming and Republicans already utilizing excessive fuel costs to assault Mr. Biden’s insurance policies, Dr. Miringoff stated asking Individuals to preserve power was not a successful technique.

The November election carries excessive stakes for Mr. Biden’s local weather agenda. Republicans have proven little urge for food for tackling international warming. In the event that they win management of 1 or each homes of Congress, the possibilities would drop significantly for enacting insurance policies to chop greenhouse gases which might be dangerously warming the planet.

For a lot of Democrats, the 1980 presidential election is seen as a cautionary story. President Jimmy Carter, who famously wore a sweater and requested Individuals to comply with his lead and switch down their thermostats in response to power shortages within the Seventies, obtained clobbered in his race for a second time period. The Senate additionally flipped to Republican management.

“That despatched a jolt into the political system that we have now not absolutely recovered from,” stated Jay Hakes, who ran the U.S. Vitality Data Administration below President Invoice Clinton and directed the Jimmy Carter Presidential Library. “In fact, Biden was there on the time.”

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However such fears take away the necessary software of power conservation, Dr. Hakes added, recalling public service advertisements from the Seventies that inspired Individuals to drive at 50 or 55 miles per hour and hold their thermostats at 68 levels. The tagline was “Don’t be fuelish.”

Half a century later, the world has a “transient and quickly closing window of alternative to safe a livable and sustainable future for all,” scientists wrote within the newest main report from the U.N. Intergovernmental Panel on Local weather Change. The report, by ​​270 researchers from 67 nations, warned that local weather change is harming the planet quicker than people can adapt.

“All people talks about emissions discount, but when the manufacturing of fossil fuels is fixed, then you definitely surprise the place these emissions reductions come from,” stated Hans-Otto Pörtner, a physiologist and one of many report’s co-chairs.

Dr. Pörtner spoke from his dwelling in northern Germany, carrying a sweater and a jacket as a result of his spouse had lowered the temperature to avoid wasting power. Such measures are “low-hanging fruit,” Dr. Pörtner stated.

He stated he hoped policymakers would use the Russian invasion as an impetus to hurry up the transition to scrub power.

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“If we overlook the existential threats concerned with local weather change, then we’re actually in hassle,” Dr. Pörtner stated.

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Mounjaro bests Ozempic for weight loss in first head-to-head comparison of real-world use

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Mounjaro bests Ozempic for weight loss in first head-to-head comparison of real-world use

In the first head-to-head comparison of two blockbuster drugs used in real-world conditions, people who took Mounjaro lost significantly more weight than their counterparts who took Ozempic — and the longer the patients kept taking the drugs, the wider the gap became.

After three months of weekly injections, patients on Ozempic lost 3.6% of their body weight, on average, while those on Mounjaro lost an average of 5.9%.

At the six-month mark, Ozempic patients had dropped an average of 5.8% of their weight, while the average weight loss for Mounjaro patients was 10.1%.

And when a full year had passed, those taking Ozempic had lost an average of 8.3% of their weight, while those taking Mounjaro had shed an average of 15.3%.

The researchers who conducted the analysis also found that compared with people on Ozempic, those on Mounjaro were 2.5 times more likely to lose at least 10% of their initial weight and more than three times as likely to lose at least 15% of their weight during their first year on the medications.

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The findings were published Monday in JAMA Internal Medicine.

Dr. Matthew Freeby, an endocrinologist and director of the Gonda Diabetes Center at UCLA’s Geffen School of Medicine, said the study results are in line with what he has observed in his own patients.

“From a weight-loss perspective, and from a sugar-lowering perspective for those with Type 2 diabetes, we see stronger effects with Mounjaro compared to Ozempic,” said Freeby, who was not involved in the research.

Both drugs were approved by the U.S. Food and Drug Administration to help people with diabetes keep their blood sugar under control. By mimicking a hormone called glucagon-like peptide 1, or GLP-1, they boost the body’s production of insulin, slow digestion, increase feelings of satiety and reduce appetite.

Mounjaro also imitates a related hormone called glucose-dependent insulinotropic peptide, or GIP.

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When the drugs were tested against placebos in clinical trials, both helped patients lose a significant amount of weight. Tirzepatide, the active ingredient in Mounjaro, appeared to be more effective than semaglutide, the active ingredient in Ozempic. But the trials weren’t conducted under the same conditions, so the results aren’t directly comparable.

Researchers from Truveta, a healthcare data and analytics company owned by 30 health systems, sought to remedy that by examining their trove of electronic health records. The work also gave them a chance to see how patients fared outside the idealized setting of a clinical trial, which typically provides free medication, regular check-ups and other types of support.

With the help of their database, the researchers were able to spot people who filled their first prescription for either drug between May 2022 — the month Mounjaro joined Ozempic in receiving FDA approval — and September 2023. Patients didn’t need to have Type 2 diabetes to be included in the study, but they did have to be overweight (with a body mass index of at least 27) or obese (with a BMI of at least 30).

The Truveta team found about 41,000 people across more than 30 states who met all their criteria for being included in the study. Since Ozempic patients outnumbered Mounjaro patients by a margin of 3-to-1, the researchers used information on age, race, income, health history and other factors to come up with a group of Ozempic patients that most closely matched the Mounjaro patients. The result was a population of nearly 18,400 who were evenly split between the two drugs.

Before their first medication dose, the average weight for people in both groups was 243 pounds. But it didn’t take long for the two groups to diverge.

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After accounting for unmeasured influences that could have skewed the results, the Truveta team found that the amount of weight lost was 2.4 percentage points higher for Mounjaro patients than for Ozempic patients after three months, 4.3 percentage points higher after six months, and 6.9 percentage points higher after a year.

Mounjaro also bested Ozempic in terms of people’s success in meting various milestones within a year of starting on one of the drugs.

Nearly 82% of Mounjaro patients lost at least 5% of their body weight, compared with 67% of patients who took Ozempic. Likewise, 62% of Mounjaro patients and 37% of Ozempic patients lost at least 10% of their initial weight, while 42% of Mounjaro patients and 18% of Ozempic patients lost at least 15% of their starting weight.

The researchers didn’t examine the biological mechanisms of the two drugs, but study leader Tricia Rodriguez, a principal applied scientist with Truveta Research, said Mounjaro may have been more effective because it works two ways instead of just one.

The big gap in effectiveness wasn’t accompanied by a measurable difference in the rate of moderate or severe side effects like bowel obstructions and pancreatitis, which were rare for patients in both groups. The researchers didn’t compare the risk of milder problems like nausea and vomiting because people wouldn’t necessarily report them to their doctors, Rodriguez said.

Regardless of which drug they took, patients with Type 2 diabetes lost less weight than patients without the disease, the researchers found. That might be explained by the fact that certain diabetes treatments can cause weight gain, and that some patients eat more throughout the day to keep their blood sugar from getting too low, Freeby said.

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It’s also possible that people who sought prescriptions for Ozempic or Mounjaro with the goal of slimming down were more motivated to keep taking the drug even if it was expensive or caused uncomfortable side effects, or that they were more likely to adopt other behaviors that promote weight loss, Rodriguez said.

Figuring this out is “a crucial topic for future research,” she said.

People currently taking Ozempic likely have a more pressing question on their minds: Should I switch to Mounjaro?

Dr. Nick Stucky, an infectious disease physician at Providence Portland Medical Center and the study’s senior author, said the results alone should not cause patients to stop taking a drug that is working for them. The risk of side effects, insurance coverage and drug availability are things to consider as well.

“While tirzepatide was significantly more effective than semaglutide, patients on both medications experienced substantial weight loss,” said Stucky, who is also Truveta’s vice president of research.

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Freeby seconded that opinion.

“If someone is doing well with a medication, why rock the boat?” he said.

Freeby added that Ozempic (and its sister medication Wegovy, which is FDA-approved specifically for weight loss) has at least one advantage over Mounjaro (and Zepbound, its weight-loss counterpart): In clinical trials, Ozempic has been shown to reduce the risk of heart attacks, strokes and other cardiovascular problems as well as kidney failure.

“At this point, we don’t have a lot of data on Mounjaro when it comes to secondary outcomes,” he said.

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LAX passenger arrested after running onto tarmac, police say

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LAX passenger arrested after running onto tarmac, police say

A Los Angeles International Airport passenger was arrested early Saturday morning after he became irate and ran out of Terminal 4 onto the tarmac, according to airport police.

The passenger appeared to be experiencing a mental health crisis, said Capt. Karla Rodriguez. “Police responded and during their attempt in taking the suspect into custody, a use of force occurred,” she said.

The man, who was not identified, was arrested on suspicion of battery against a police officer and trespassing on airport property, she said. He was taken to a nearby hospital for a mental health evaluation.

A video obtained by CBS shows a shirtless man in black shorts running on the tarmac past an American Airlines jetliner with a police officer in pursuit. The officer soon tackles the man and pushes him down on the pavement.

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Video: How SpaceX Is Harming Delicate Ecosystems

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Video: How SpaceX Is Harming Delicate Ecosystems

On at least 19 occasions since 2019, SpaceX’s operations have caused fires, leaks and explosions near its launch site in Boca Chica, Texas. These incidents reflect a broader debate over how to balance technological and economic progress against protections of delicate ecosystems and local communities. The New York Times investigative reporter Eric Lipton explains.

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