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Jimmy Carter’s final foe: A parasitic worm that preyed on millions in Africa and Asia

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Jimmy Carter’s final foe: A parasitic worm that preyed on millions in Africa and Asia

Only a few hours earlier than President Carter underwent his first radiation remedy for mind most cancers, he spoke of his hope, within the time he had left, to purge the world of a parasitic worm illness.

That was in 2015.

“I’d just like the final Guinea worm to die earlier than I do,” the thirty ninth president advised reporters on the Carter Heart. “We all know the place all of them are, so clearly that may be my prime precedence.”

Carter had arrange the worldwide Guinea Worm Eradication Program in 1986, when about 3.5 million folks throughout rural Africa and Asia have been stricken by the excruciating parasite that has plagued people for 1000’s of years.

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The 98-year-old, now in hospice at house in Plains, Ga., is on the cusp of reaching his objective: The variety of reported human instances dwindled in 2022 to 13 — an all-time low.

“We’ve joked many occasions: Who’s going to win — the Guinea worm or Jimmy Carter?” mentioned Dr. Peter Bourne, Carter’s former drug czar who grew to become an assistant secretary-general on the United Nations. “13 is fairly near zero. For the hundreds of thousands of people that didn’t get the Guinea worm an infection, he has had an infinite influence.”

One of many excellent achievements of the Carter presidency was the 1979 peace settlement between Israel and Egypt. Many years later, the prospect of peace within the Center East is dismal, and Carter’s most enduring international legacy may very well be making Guinea worm the second infectious human illness to be eradicated, after smallpox in 1980.

“His position was essential,” Bourne mentioned. “He would name folks just like the president of Ghana and say, ‘I need to discuss to you about Guinea worm.’ It was troublesome sufficient to get the minister of well being on the telephone, and to get a president to speak about Guinea worm was no simple feat. However they might all reply to him.”

A well being employee removes a Guinea worm from a baby’s foot in Savelugu, Ghana, in 2007.

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(Olivier Asselin / Related Press)

The Latin title of Guinea worm illness — Dracunculiasis — means “affliction with little dragons.” The calcified stays of the worm have been present in a 3,000-year-old Egyptian mummy of a 13-year-old lady, and a few students consider they might have been the “fiery serpents” the Previous Testomony describes as attacking the Israelites within the desert.

People contract the parasite after ingesting stagnant water infested with tiny crustaceans which have swallowed microscopic Guinea worm larvae. After an incubation interval of a few 12 months, the larvae develop into noodle-like worms as much as 3 ft lengthy that wrap round tendons, ligaments and connective tissue. They launch a burning acid that blisters the pores and skin, permitting them to poke their head out of a leg, foot or arm, and in some instances a breast or scrotum.

The worm’s exit is so agonizing that it forestall children from going to highschool and adults from farming, cooking and accumulating firewood. Ridding the physique of the parasite takes weeks. First, the worm is wrapped onto a rolled piece of gauze or stick. Then the stick is twisted to slowly pull out the worm, about an inch a day.

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In 1988, Carter encountered the Guinea worm for the primary time within the village of Denchira close to Accra, the Ghanian capital. About half the village’s 500 inhabitants have been contaminated, some so crippled that they may not depart their huts. Carter noticed a younger lady he thought was cradling a child within the criminal of her proper arm, however when he approached, he realized she was not holding an toddler.

“Her proper breast, which was about greater than a foot lengthy … had a Guinea worm rising from the nipple,” Carter mentioned in 2016.

“Nicely, we are able to’t depart them like this,” Carter mentioned after his go to to Denchira.

The Carter Heart labored with the Ministry of Well being to carry each identified intervention to the village, mentioned Dr. Donald R. Hopkins, who led the middle’s efforts to eradicate the illness from 1987 to 2015. Practically a 12 months and a half later, Carter went again to Denchira to seek out the parasite virtually gone.

Jimmy Carter speaks into a microphone as a group of youths and adults look on

Former President Carter addresses youngsters at Savelugu Hospital in Ghana in 2007.

(Louise Gubb / Carter Heart)

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Adam Weiss, the director of the middle’s Guinea Worm Eradication Program, mentioned Carter would attempt to console sufferers and maintain their arms as they shrieked when the worm emerged.

“It’s a type of issues that after you see it, you possibly can’t unsee it,” Weiss mentioned. “Even among the most stoic males in South Sudan, this brings them to their knees. They cry. They don’t need to admit it, however they do. It’s one thing you possibly can’t stroll away from.”

Over time, Carter’s visits to rural Africa impressed 1000’s of schoolchildren to line highways to see him. In Nigeria, Carter mentioned, a bunch of youngsters held a giant signal that mentioned, “Be careful, Guinea worm, right here comes Jimmy Carter!”

A boy leaning on his arms as a man inspects his leg

Adam Weiss examines 10-year-old Fusini Adam’s leg for Guinea worm illness within the village of Nyujaguyili in northern Ghana in 2006.

(E. Staub / Carter Heart)

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Carter first thought of the potential of eradicating Guinea worm when he was within the White Home. As smallpox was on the verge of being eradicated in 1977, Carter requested Bourne if there was every other illness that would have the identical influence.

Bourne advised Carter that the Guinea worm would most likely be the best international infectious illness to eradicate: Not like smallpox, it may very well be eradicated with out a drugs or vaccine. Prevention may very well be achieved by exhibiting villagers how one can make their water provide secure — filtering ingesting water and stopping the contaminated from strolling into stagnant ponds and spreading larvae — coupled with vigilant monitoring of the illness.

However there was an issue: Guinea worm illness didn’t exist in america.

“We determined that the Guinea worm was so obscure that nobody within the U.S. would concentrate,” Bourne mentioned. “I believed that he isn’t going to need to deplete any political credit score.”

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That calculus modified when Carter left the White Home in 1981 and a 12 months later based the Carter Heart. By that time, Bourne was working on the United Nations, heading a 10-year program to supply folks world wide with clear ingesting water.

After talking on the Carter Heart on the significance of unpolluted ingesting water, Bourne mentioned he hosted the Carters on a trout fishing trip at his farm in Wales and requested the previous president to be the figurehead for the marketing campaign to struggle the parasitic illness.

“I advised him: You might eradicate Guinea worm in your lifetime,” Bourne mentioned. “It’s one thing that may have international influence, and also you don’t have to fret about doing it only for a U.S. viewers.”

FILE - Children in the town of Terekeka, South Sudan, draw water, Oct. 4, 2017, from a stagnant pond

Youngsters within the city of Terekeka, South Sudan, draw water, Oct. 4, 2017, from a stagnant pond that was as soon as contaminated with Guinea worm when the city was endemic. (AP Photograph/Mariah Quesada, File)

(Mariah Quesada / Related Press)

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Together with his presidency behind him, Carter had extra freedom. He made eliminating Guinea worm one of many Carter Heart’s priorities, together with 5 different preventable ailments: river blindness, trachoma, schistosomiasis, lymphatic filariasis and malaria.

At first, participating overseas leaders was a problem as a result of Guinea worm is usually a rural affliction.

“We discovered no person else wished to cope with this illness as a result of it impacts remoted villages within the desert areas and likewise within the jungle areas,” Carter mentioned to the Commonwealth Membership of California.

When Hopkins went from the U.S. Facilities for Illness Management and Prevention to the Carter Heart to direct the Guinea Worm Eradication Program, Carter would continually inform him he was not calling him sufficient to ask for his assist.

“I didn’t need to hassle a former president of america each time I bumped into an issue in a single nation or one other; I attempted to save lots of that huge factor for the massive issues,” Hopkins mentioned. “However he insisted.”

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As Carter labored intently with ministries of well being, native volunteers and organizations such because the CDC and the World Well being Group, the Guinea worm case rely plummeted from the three.5 million in 1986 to 623,579 in 1990 to 75,223 in 2000.

The illness was eradicated in 17 international locations, together with Pakistan, Kenya, India, Yemen, Senegal and Cameroon.

In some areas, this system was stalled by civil conflict. However in some instances, the push to eradicate the Guinea worm helped foster peace.

In 1995, Carter negotiated a four-month “Guinea Worm Stop-Fireplace” within the Sudanese civil conflict, the longest humanitarian cease-fire in historical past on the time, permitting well being employees to entry virtually 2,000 endemic villages and distribute water filters. Till then, the middle’s technique had been to attend till the top of the civil conflict earlier than embarking on its public well being mission.

For some time, it seemed as if Carter would outlive the final Guinea worm. However in 2012, this system skilled a setback: The parasite was spreading amongst stray canine in Chad, a nation that had gone a decade with out human infections.

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Well being employees launched new measures akin to chaining contaminated canine to maintain them out of water, which has considerably diminished transmission amongst canines. In 2022, six provisional human instances have been reported in Chad, 5 in South Sudan, one in Ethiopia, and one within the Central African Republic.

Weiss mentioned he and his colleagues on the Carter Heart— together with greater than 30,000 volunteers working in areas beneath energetic surveillance — are decided to proceed Carter’s legacy.

“He mentioned let’s get it finished earlier than I depart planet Earth, and that has actually given us a variety of motivation,” Weiss mentioned. “We hold doubling down the eye and rigor as eradication calls for. You miss one case, and you’ll be set again years, so we don’t take that evenly, and neither did he.”

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L.A. County plans to put $5 million toward wiping out medical debt

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L.A. County plans to put $5 million toward wiping out medical debt

Los Angeles County is moving forward with a pilot program to relieve medical debt for struggling residents, setting aside $5 million for a planned agreement with a national nonprofit that buys and erases such debts.

County supervisors voted Tuesday to allocate money for a county agreement with Undue Medical Debt to carry out the new program. The effort is expected to launch later this year, focusing on debt stemming from hospital care and targeting L.A. County’s “lowest income residents.”

“No one should be driven into poverty because they got sick,” Supervisor Janice Hahn, who put forward the proposal with Supervisor Holly Mitchell, said in a statement.

“But medical debt remains a huge problem in this country, and it can be devastating for families and their financial well-being. Luckily for us, we have an opportunity to make a difference.”

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Hospitals stuck with unpaid bills can bundle and sell the debt at a discount to collection agencies that try to recoup the owed money for profit. Undue Medical Debt instead buys the discounted debt and forgives it. The nonprofit said it can erase an average of $100 in debt for every dollar that is donated.

“Five million dollars can really go a long way,” said its vice president of communications and marketing Daniel Lempert. County officials estimated that amount could eliminate $500 million of debt for 150,000 residents.

Across the country, Undue Medical Debt has partnered with local governments such as Cook County, Ill. and Toledo, Ohio. to fund such efforts. Lempert said that under such agreements, the nonprofit typically reaches out to local hospitals and other health care providers to identify and purchase medical debt affecting financially strapped patients, then gets reimbursed by the local government for the cost of debts affecting their residents.

Under its guidelines for financial hardship, Undue Medical Debt works to relieve debt for people from households making no more than four times the federal poverty level — a calculation equating to $124,800 this year for a family of four — or whose medical debt amounts to 5% or more of their income.

L.A. County is still working out who will be eligible under its pilot program, but its broad goal is to reach “our lowest-income residents and the working poor who have catastrophic amounts of medical debt,” said Dr. Naman Shah, director of the division of medical and dental affairs at L.A. County Public Health.

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The L.A. County pilot program will focus specifically on medical debts for hospital care, Shah said. Local residents cannot apply directly for their medical debt to be wiped out, but will be informed if Undue Medical Debt has eliminated some or all of their unpaid debt.

“You’ll get a letter out of the blue saying, ‘X, Y or Z debts have been relieved. You no longer owe them. Keep this as a receipt,’” Lempert said.

In Los Angeles County, public health officials have estimated that medical debt totaled more than $2.9 billion in 2022, burdening 1 in 10 adults in the county — a higher percentage than suffered from asthma, according to the public health department. More than half of those who said they were burdened by medical debt had taken on credit card debt to pay medical bills, its analysis found.

The problem has persisted even as more L.A. County residents gained insurance coverage, underscoring the need for a targeted approach, the public health department said.

County officials estimated earlier this year that wiping out nearly $3 billion in medical debt for L.A. County residents through an intermediary would cost $24 million. Other municipalities have turned to funding from the American Rescue Plan Act for such debt relief, but L.A. County had “fully allocated” that money as of January, according to a staff report.

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The public health department said it planned to instead use $5 million in one-time county funding for the pilot program, which it said would roll out in stages, starting with “the most vulnerable residents.” Shah said his hope was to raise enough additional money to not have to set priorities about which struggling residents to help.

A study released earlier this year raised questions about the effectiveness of buying up medical debt: A National Bureau of Economic Research working paper that examined medical debt relief for more than 83,000 people from 2018 to 2020 concluded it had no effect, on average, on financial distress or mental health. The research was done in partnership with Undue Medical Debt, then known as RIP Medical Debt.

Despite the “disappointing results,” the researchers wrote, “there is still potential that medical debt relief targeted further upstream or in different populations could yield meaningful benefits.” Stanford University professor of economics Neale Mahoney said the cheapest debts to buy often date back five years or more.

By that point, “a lot of these folks had a lot of other issues, and relieving one of their issues without helping … all of the other financial issues they had wasn’t enough to move the needle,” he said. One solution is to “move more upstream,” and provide debt relief earlier, “before people are too scarred by the debt collection process.”

Mahoney praised the response of the nonprofit, saying it was “taking the study to heart.” Undue Medical Debt president Allison Sesso said in April that it had already made changes since the period covered by the study, including buying medical debt directly from hospitals before it goes to debt buyers or collection agencies.

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Sesso also said her group was “collaborating with local governments across the country to concentrate debt erasure to a specific locality to deepen our impact.”

Focusing such efforts in a targeted area ramps up the chances it may be able to wipe out multiple debts for an individual patient, Lempert said.

Shah added that the study did not show what would happen if debt relief happened alongside other prevention efforts. In L.A. County, “there is a larger agenda on medical debt — of which this is just one part.”

Under a broader plan to combat medical debt in L.A. County, the public health department also wants to gather data on how hospitals collect debt and assist strapped patients, create an online portal to apply for financial help, and expand legal aid services, among other proposed steps.

Public health department director Barbara Ferrer told county supervisors Tuesday that their goal is to stop medical debt “at the source,” before it starts piling up for L.A. County residents.

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“We don’t want to be coming back to you in five years trying to pay off medical debt again,” Ferrer said.

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L.A.'s newest dinosaur has its forever name

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L.A.'s newest dinosaur has its forever name

The people have spoken, and L.A.’s newest Jurassic-era resident has its forever name.

Dinosaur fans who responded to the museum’s request for input overwhelmingly chose to call the Natural History Museum’s new 70-foot-long sauropod “Gnatalie.”

More than 36% of roughly 8,100 participants in a public poll chose that name, which is pronounced “Natalie,” from among five options offered by the museum.

A rendering of the new dinosaur display at the Natural History Museum. Dinosaur fans who responded to a museum poll have decided to call the 70-foot-long sauropod “Gnatalie.”

(Frederick Fisher and Partners, Studio MLA, and Studio Joseph / NHMLAC)

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The punny moniker is a reference to the relentless swarm of gnats that plagued paleontologists, students, museum staff and volunteers during the 13-year effort to unearth the dinosaur’s remains from a quarry in southeast Utah. Museum staff nicknamed the dinosaur Gnatalie while they were still digging it up, a process that lasted from 2007 to 2019.

The long-necked, long-tailed skeleton will be the focal point of the NHM Commons, a $75 million welcome center currently under construction on the southwest end of the museum in Exposition Park. Slated to open this fall, the Commons will offer gardens, an outdoor plaza, a 400-seat theater and a glass-walled welcome center that can be toured without a ticket.

“The efforts of hundreds of people contributed to what you see here, ground to mount,” said paleontologist Luis Chiappe, director of the Dinosaur Institute at the Natural History Museum of Los Angeles County.

The specimen appears to be part of a new species, similar to the Diplodocus, which will be scientifically named in the future. Thanks to celadonite minerals that replaced organic matter during the fossilization process, the mounted skeleton has a unique greenish-brown hue.

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The skeleton is made up of about 350 fossils from six different animals whose bones washed into a river after death some 150 million years ago and commingled.

“We are delighted to see how many people voted and how much they loved our name for this unusual dinosaur,” said Lori Bettison-Varga, President and Director of the Natural History Museums of Los Angeles County.

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Mexico may legalize magic mushrooms. Will this traditional medicine lose its meaning?

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Mexico may legalize magic mushrooms. Will this traditional medicine lose its meaning?

Alejandrina Pedro Castañeda opened a brown paper package and pulled out a handful of magic mushrooms, which many residents of this Indigenous Oaxacan town tenderly refer to as “child saints” or “the little ones that sprout.”

Then she handed each of her six visitors — who had driven seven hours from Mexico City and paid up to $350 apiece for a healing retreat — a generously sized portion, prompting a few dubious looks.

It was nighttime, and the guests were sitting in a hut that was barely illuminated by two candles, making it difficult for them to see what they were about to eat.

Pedro Castañeda has used mushrooms in her healing practice for years and was comfortable stepping outside as the group crunched slowly in silence.

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One person said the fungi tasted like stale popcorn. Another tasted dirt.

The healer returned a few minutes later.

“Now we’re starting the trip,” she said. “Let’s go to work.”

Indigenous communities in Mexico have long considered psychedelic mushrooms to be intermediaries to the spiritual world. But their growing popularity outside of Mexico has spurred a debate over who should have access to them and whether science and Indigenous medicine can or should be reconciled.

Magic mushrooms have been used in Mesoamerican religious rituals since pre-Hispanic times. But it wasn’t until the 1950s that a New York banker and mushroom enthusiast named R. Gordon Wasson made them famous — perhaps too famous — in the Western world.

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(Alejandra Rajal / For The Times)

Some Indigenous healers are courting tourists. Scientists interested in their chemical properties have been studying mushrooms in hopes of developing treatments for depression and other mental health problems. And growing demand from recreational users has fueled a thriving black market.

Currently, the fungi can only be used in Indigenous rituals or in government-approved research. But a senate bill proposes making psilocybin, a psychedelic compound in the mushrooms, more widely available.

In addition to making psilocybin available to anyone with a doctor’s prescription, the bill would permit therapy that uses the actual mushroom that a government office of traditional medicine would help regulate. It also calls for scientific research on Indigenous medicine and providing compensation to Indigenous people for “patents” involving their traditions.

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The bill’s supporters say that they’re trying to protect Indigenous medicine by making sure the traditional use of magic mushrooms is enshrined into law.

But the prospect of expanding the availability of magic mushrooms has created friction within Indigenous communities that have used them for centuries. Will the spirituality associated with this traditional medicine be lost?

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Magic mushrooms have been used in Mesoamerican religious rituals since pre-Hispanic times. A mural from the ancient city of Teotihuacán, just outside Mexico City, shows the Toltec rain god Tlaloc with two figures alongside him holding mushrooms that have risen from where his raindrops fell. A Franciscan missionary documenting 16th century life in New Spain referred to the mushrooms as the “flesh of the gods.”

But it wasn’t until the 1950s that a New York banker and mushroom enthusiast named R. Gordon Wasson made Mexico’s magic mushrooms famous — perhaps too famous — in the Western world.

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On a trip to Huautla, in southern Mexico, he ate mushrooms with Indigenous Mazatec healer María Sabina and wrote about the experience in a 1957 article for Life magazine titled “ Seeking the Magic Mushroom.” The story inspired thousands to travel to Huautla — some seeking out Sabina. The Mexican press described the foreigners as addicts, and the military ultimately set up a checkpoint on the road to Huautla to try to block the outsiders.

In July 1970, Reuters reported: “Hundreds of hippies are braving imprisonment and fines to penetrate this mushroom paradise in the State of Oaxaca, where the authorities are conducting a drive against mushroom eaters.”

Wasson said he felt guilty about the crowds in a New York Times op-ed published later that year. A “humble out-of-the-way” town had been overrun by “a torrent of commercial exploitation of the vilest kind.”

“The old ways are dead,” he wrote, “and I fear that my responsibility is heavy, mine and María Sabina’s.”

In an interview toward the end of her life, Sabina described how some outsiders would take the mushrooms “at whatever time and whatever place” and “don’t use them to cure themselves of a sickness.”

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“From the moment the foreigners arrived to search for God,” she said, “the saint children lost their purity.”

In the mid-20th century, psilocybin was classified as a Schedule I substance in the U.S. — which put the kibosh on research. But interest in scientific research on mental health and psilocybin was rekindled in the 1990s.

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Psilocybin is thought to boost neuroplasticity, the brain’s ability to form new neural connections, and research indicates that it may be successful in treating depression, anxiety and substance abuse. Parts of the United States have legalized or decriminalized the substance. (Oakland decriminalized magic mushrooms in 2019.)

“That plasticity enhancement may allow people to shift how their brain is functioning into a mode that’s more helpful, more adaptive, that’s going to promote mental health,” said Greg Fonzo, who co-directs the Center for Psychedelic Research & Therapy at the Dell Medical School at the University of Texas at Austin.

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Alejandrina Pedro Castaneda has used mushrooms in her healing practice for years.

Alejandrina Pedro Castaneda, who has used mushrooms in her healing practice for years, hosts a mushroom ceremony once or twice a week.

(Alejandra Rajal / For The Times)

Some people who ingest magic mushrooms report overwhelming feelings of joy or the presence of family. Others have said they feel deeply sad or that they are having an out-of-body experience.

The risk of a lethal overdose is considered very low, Fonzo said. What’s more common is having a difficult experience or a “bad trip” due to anxiety.

Pedro Castañeda, who compares the bill with a birth certificate, supports the legislation, insisting the world must not forget that the Mazatecs, as well as other Indigenous communities, have preserved rituals with magic mushrooms for centuries.

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“The medicine is not protected now. It’s out of control,” she said. “Everyone has it in their home, like cannabis,” she said, referring to black market purchases. “What we need is a record that says the Mazatecs are the custodians, the Mazatecs are the ones that for millennia have defended the medicine.”

But other Mazatecs in Huautla are worried about appropriation and misuse, that traditions associated with Indigenous culture will be disrespected as increasing numbers of people rush to pick up their prescriptions.

In an Indigenous mushroom ceremony, the healer will use mushrooms to communicate with their spiritual world to inquire about a patient’s illness. A patient may also experience revelations.

If the bill passes, “It’ll be taken like an aspirin,” said Isaias Escudero Rodriguez, a local doctor. It will no longer have the “spirituality that it carries for us.”

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The push to legalize magic mushrooms in Mexico dates back to the early days of the pandemic. Alejandra Lagunes, 52, a senator in Mexico’s national congress, started to experience anxiety attacks that were reminiscent of the severe depression she suffered in her 20s. The depression from decades ago, she said, was resolved after she took ayahuasca — a psychoactive brew made from the Amazonian Banisteriopsis caapi vine — with an Indigenous healer.

Lagunes researched psychedelics and introduced legislation in November to increase access to magic mushrooms while recognizing the long tradition of Indigenous medicine. She hopes it opens the door for non-Indigenous Mexicans to learn from Indigenous practices.

The initiative has supporters at Mexico’s National Institute of Psychiatry, where scientists have government permission to investigate the potential therapeutic effects of magic mushrooms.

Jesús María González Mariscal, a clinical psychologist in Mexico City who has advised the senator, said much can be learned from traditional medicine, including the importance of companionship in Mazatec mushroom ceremonies. These ceremonies occur at night under the guidance of a healer with candles, flowers, incense and an altar with Catholic images. A patient’s family members may accompany them.

The result, Mariscal said, “is a space of care and protection so a person can explore their inner world in a context that’s safe, trustworthy and ethical” — and that’s what Mexico City psychotherapist Oscar O’Farrill is trying to teach his students.

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O’Farrill runs a master’s and doctoral degree program affiliated with the National School of Psychologists and Experts of Mexico where his approximately dozen students listen to Indigenous guest speakers talk about traditional medicine. He schedules group therapies in his home, a two-story house where a large container on his kitchen counter has powder from lion’s mane, a non-psychedelic mushroom, that he takes with his morning coffee. Indigenous healers have led his students through ceremonies with mushrooms, peyote and bufo, the smoked secretions of a Sonoran desert toad.

“Psychiatry in this moment can’t understand what psilocybin is if it doesn’t understand all the aspects of the customs of Indigenous people,” he said. “Like it or not, the mushrooms have a spirit.”

But Eros Quintero, a biologist who co-founded the Mexican Society of Psilocybin in 2019, said he would have preferred that Indigenous communities were not singled out in the bill, that psilocybin simply be reclassified.

Indigenous people, he said, may not view illness through the prism of Western science. In Mazatec culture, for example, people may believe that a person fell ill because they walked through a cave where spirits are thought to reside or broke a communal rule.

“They have their own traditions and their own way of seeing things, and what we see is that there are few who are interested in what we’re interested in with psilocybin,” he said.

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Huautla presents itself as a place for the mushroom-seeker.

Taxis decorated with images of small mushrooms speed up and down narrow mountain roads that are lined with tin-roofed houses. In the summer, when mushrooms are in season, locals wait by a bus terminal to offer the fungi to tourists. Prices vary, but a dozen pairs of mushrooms (they’re sold by the pair) may cost $25 and a ceremony can cost $90 or more. After mushroom season, the fungi are often preserved in jars with honey.

Several signs announce the home of the family of María Sabina — who died in poverty in 1985 but whose life has since been celebrated in Mexican culture. Her descendants, who live on the property where Sabina once resided, maintain a small museum filled with portraits of the healer and sell mushroom-themed crafts.

Anselmo García Martínez, a farmer and a great-grandson of Sabina, says he was about 6 when he tried mushrooms for the first time during a ceremony with relatives who were accompanying a sick family member. (Many other locals say they first consumed mushrooms as children.)

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Like some other residents, he said he didn’t mind if mushrooms are allowed outside Indigenous rituals because the general public already has access to them through the black market.

But he issued a reminder: “For us, for the Mazatecs, it’s something sacred.”

Lagunes said she’s invited Indigenous people to the forums she has sponsored, and last year she posted a video on the social media platform X that showed her with several healers and indigenous people in Huautla. They presented her with a baton that she said she’d carry to “bring the voice and knowledge of ancestral medicine to the place that it deserves.”

But some opponents have said that the Mazatec people haven’t been properly consulted on whether the bill should move forward, reminding supporters that, for the moment, there is no infrastructure to make it happen. Santos Martínez, one of the founders of Caracol Mazateco, a civil society group focused on preserving Mazatec culture, agrees there hasn’t been enough outreach to the Mazatecs.

Martinez said his experiences with magic mushrooms transformed his life. As a medical student working at a clinic in the state of Puebla, he fell into a depression after seeing patients suffer from inadequate care. He returned to his community in Huautla, where he participated in mushroom ceremonies, hoping they would help him find direction in his life.

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During the ceremonies he felt happy and had visions of family members, including his grandfather. “It was as if he was saying, ‘adelante, hijo,’” he said, or, “go forward, son.”

Francisco Javier Hernandez García, a Huautla healer who leads mushroom ceremonies for tourists almost daily at some points of the summer, fears that mushrooms will “lose respect” if they are legalized for therapy outside of the Indigenous context.

Like others, he spoke about mushrooms as carrying wisdom.

“They sprout because they are waiting for that person,” he said, referring to the one who will eat them. “They already know who carries problems.”

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In mid-April, O’Farrill organized a trip for six people — including himself — to visit Pedro Castañeda for the healing retreat. Two people, a man who works for a Wall Street asset management firm and a woman training to guide people during mushroom trips, had flown in from the U.S. A mother and daughter, both psychologists, and a literary editor were from Mexico.

They spent three days at the home of Pedro Castañeda, who lives with eight dogs in a house that has several floors under construction. She hosts a mushroom ceremony for locals or tourists once or twice a week and said that the “great spirit” tells her how many mushrooms to give each person.

The members of O’Farrill’s group had individual therapy sessions with Pedro Castañeda in which she asked them about their insecurities. After her guests ate mushrooms, Pedro Castañeda asked several of them to sing. At one point, the editor began to suddenly cry, and the younger psychologist said she felt pain, prompting the healer to rigorously brush her with a feather in a cleansing ritual. A few minutes later, the psychologist said she was having visions of “injustice in jail.”

The next morning, the group hiked — mostly barefoot — the Mountain of Adoration, which the Mazatecs consider sacred.

At the top of the mountain, which overlooked Huautla, the healer gave each person cacao beans to leave as an offering, giving thanks for the previous night. They placed them on a tower of rocks jutting out from the mountain, next to many little mounds of cacao left earlier by other visitors.

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