Nuno F.G. Loureiro, a 47-year-old physicist and fusion scientist, was shot Monday night at his home in Brookline, Massachusetts. He died at a local hospital on Tuesday, the Norfolk District Attorney’s Office said in a statement.

The prosecutor’s office said no suspects had been taken into custody as of Tuesday afternoon, and that its investigation was ongoing.

Loureiro, who joined MIT in 2016, was named last year to lead MIT’s Plasma Science and Fusion Center, where he aimed to advance clean energy technology and other research. The center, one of the school’s largest labs, had more than 250 people working across seven buildings when he took the helm.

Loureiro, who was married, grew up in Viseu, in central Portugal, and studied in Lisbon before earning a doctorate in London, according to MIT. He was a researcher at an institute for nuclear fusion in Lisbon before joining MIT, it said.

“He shone a bright light as a mentor, friend, teacher, colleague and leader, and was universally admired for his articulate, compassionate manner,” Dennis Whyte, an engineering professor who previously led MIT’s Plasma Science and Fusion Center, told a campus publication.

The president of MIT, Sally Kornbluth, said in a statement that Loureiro’s death was a “shocking loss.”

The homicide investigation in Brookline comes as police in Providence, Rhode Island, about 50 miles away, continue to search for the gunman who killed two students and injured nine others at Brown University on Saturday. The FBI on Tuesday said it knew of no connection between the crimes.

A 22-year-old student at Boston University who lives near Loureiro’s apartment in Brookline told The Boston Globe she heard three loud noises Monday evening and feared it was gunfire. “I had never heard anything so loud, so I assumed they were gunshots,” Liv Schachner was quoted as saying. “It’s difficult to grasp. It just seems like it keeps happening.”

Some of Loureiro’s students visited his home, an apartment in a three-story brick building, Tuesday afternoon to pay their respects, the Globe reported.

The U.S. ambassador to Portugal, John J. Arrigo, expressed his condolences in an online post that honored Loureiro for his leadership and contributions to science.

“It’s not hyperbole to say MIT is where you go to find solutions to humanity’s biggest problems,” Loureiro said when he was named to lead the plasma science lab last year. “Fusion energy will change the course of human history.”

CONCORD, NH — The Powerball jackpot for Wednesday night is expected to be the sixth largest in history, according to the New Hampshire Lottery.

The jackpot is expected to be $1.25 billion. The one-time cash payout should be around $572 million before taxes. No one has won the jackpot since Sept. 6, when winners who purchased tickets in Missouri and Texas split a $1.78 billion jackpot.

Top 10 Jackpots

1. $2.04 Billion, Nov. 7, 2022
2. $1.787 Billion, Sept. 6, 2025
3. $1.765 Billion, Oct. 11, 2023
4. $1.586 Billion, Jan. 13, 2016
5. $1.326 Billion, April 6, 2024
6. $1.25 Billion, Dec. 17, 2025 (anticipated)
7. $1.08 Billion, July 19, 2023
8. $842.4 Million, Jan. 1, 2024
9. $768.4 Million, March 27, 2019
10. $758.7 Million, Aug. 23, 2017

The odds of winning the jackpot are 292.2 million to 1. The odds of winning the $1 million prize — matching five numbers without the Powerball are 1 in 11.7 million.

Charlie McIntyre, the executive director of the New Hampshire Lottery, said last week, $2.4 million worth of tickets were sold in the state.

“We’ve gone a number of drawings without a winner, giving this Powerball jackpot plenty of time to rise to the sixth largest of all time,” said “There’s still time to make your holiday season brighter with a chance at this $1.25 billion prize — all you need is $2 to play.”

Revenue from the sales, he said, helps the commission “continue our daily mission to deliver the maximum amount of revenue to public schools in New Hampshire.”

Since 1964, more than $3 billion has been contributed to schools in the Granite State.