Pittsburg, PA
Pittsburgh doctor hopes FDA-approved colon cancer blood tests boosts screening rates

PITTSBURGH (KDKA) — A simple blood test to screen for colorectal cancer was approved by the U.S. Food and Drug Administration.
According to the American Cancer Society, 53,000 people will die of colorectal cancer this year and less than 60 percent follow screening guidelines. Doctors are hoping the newly approved screening tool will help change that.
“I’m very happy that we have an additional tool in our toolbox to help people get screened for colon cancer,” said Dr. James McCormick, chief of colon and rectal surgery at Allegheny Health Network.
Dr. McCormick is excited about the FDA-approved first-of-its-kind blood test. It’s meant for people 45 and older with an average risk for the disease.
“You just get your blood drawn. What they’re doing is looking in the blood for circulating tumor DNA. So, DNA that the tumor will have released into the blood, and it would be able to detect that,” Dr. McCormick said.
In Guardant Health’s clinical trials, the blood test was 83 percent accurate in detecting cancer that’s already formed.
“That’s someone who’s already has a cancer. For the precancer solutions, unfortunately, it’s down in the 13 to 20% range that it can pick that up. So, it’s not going to pick up those polyps before they become cancer,” he said.
The Shield test is not a replacement for colonoscopies. Any positive blood test result would then require a colonoscopy.
“It’s different from a colonoscopy, which is the traditional screening test that we offer people, where we can take precancerous tumors at the time of the colonoscopy and remove them before they can become cancerous tumors. That’s still the best screening test, and really the only test that you should have if you have any symptoms at any age,” Dr. McCormick said.
McCormick reiterated that people who get symptoms at any age should get screened and that everyone should be screened for colon cancer at age 45. He said despite efforts to spread the word, 20 or 25 percent of people never get screened.
He hopes the blood test will help boost the rate of screenings and save more lives.
“If there’s a reason that they’re not getting screened that is solved by the Shield test, then we’ll take it. We’ll get them in that way,” Dr. McCormick said.
This approval comes at a time when more people have been developing colon cancer at younger ages.
“We’re even seeing patients in their 20s and 30s with colon cancer, even with no family history. And we have no idea why or who is going to be affected by this,” Dr. McCormick said.
He said never to ignore symptoms. If something is different with your bowel, fight for yourself and make sure you get the test you need.
“Anytime there’s bleeding, there’s abdominal pain, anytime there’s a change in the way your bowels work that persists more than just a few weeks, definitely call your doctor and insist upon getting a colonoscopy,” Dr. McCormick said.
The Shield test has been used by doctors for high-risk surveillance after treatment. A stool test is another screening tool that’s available.
Dr. McCormick said if a blood test and a stool test are negative, those would probably be repeated every three years. Negative colonoscopies only need to be done every 10 years.

Pittsburg, PA
Pirates Designate Relief Pitcher for Assignment

PITTSBURGH — The Pittsburgh Pirates have made two roster moves, one of which changes their bullpen.
Alex Stumpf of MLB.com reported that the Pirates claimed utilityman Ronny Simón off waivers from the Marlins and designated right-handed pitcher Tanner Rainey for assignment to make a spot on the 40-man roster.
The Pirates signed Rainey to a minor league contract on Dec. 6, 2024 and he started the season with Triple-A Indianapolis, after spending some time on the 7-day Injured List.
Rainey pitched in nine games out of the bullpen for Indianapolis, allowing six earned runs over 9.0 innings pitched for a 6.00 ERA, with 12 strikeouts to four walks and a .212 opposing batting average.
The Pirates selected Rainey’s contract on May 3, after they placed shortstop Isiah Kiner-Falefa on the 10-day Injured List and transferred fellow right-handed relief pitcher Justin Lawrence from the 10-day Injured List to the 60-day Injured List, making room for Rainey on the 40-man roster.
Rainey struggled in his month with the Pirates, with a 10.57 ERA over 7.2 innings pitched, nine earned runs allowed in 11 appearances, nine strikeouts to six walks and an opposing batting average of .250.
He did post eight scoreless outings, but did allow three runs in the eighth inning to the Atlanta Braves on May 11 at PNC Park, tying the game up at 3-3, and two runs vs. the Milwaukee Brewers on May 23 at home, giving the road team a 3-2 lead.
Rainey had his worst outing in the last game for the Pirates, a 6-4 defeat to the San Diego Padres at Petco Park on June 1.
He had a 4-2 lead, but immediately walked Padres desginated hitter Xander Bogaerts and then walked shortstop Jose Iglesias after a flyout. He also allowed an RBI-single to Padres pinch-hitter Elíaz Díaz and walked right fielder Fernando Tatís Jr., loading the bases with just one out.
Pirates manager Don Kelly brought in left-handed pitcher Caleb Ferguson, who hadn’t allowed an inherited run all season. Ferguson then gave up a single, a sacrifice fly, a walk and another single, as the Padres took a two-run lead and won the game.
Rainey finished that day with just 0.1 innings pitched and four earned runs on his scoreline.
The Pirates bullpen consists of right-handed pitchers in rookie Brashton Ashcraft, David Bednar, Dennis Santana and Chase Shugart, plus left-handed pitchers in Ryan Borucki, Joey Wentz and Ferguson.
Make sure to visit Pirates OnSI for the latest news, updates, interviews and insight on the Pittsburgh Pirates
Pittsburg, PA
Pirates Bullpen Squanders Lead in Loss to Padres

The Pittsburgh Pirates’ (22-38) blew an early lead as their bullpen faltered in a 6-4 loss against the San Diego Padres (33-24) on Sunday afternoon at Petco Park.
The rubber match handed the Pirates a series loss against San Diego. Pittsburgh went 3-3 during this week’s West Coast road trip.
Going into the bottom of the seventh inning, it looked like the Pirates were going to finish out their West Coast travels with another series win. But the Pirates bullpen squandered a 4-1 lead, and the Buccos’ bats were quiet after the fourth inning. It was another close loss, but one that the Pirates would have liked to hold on to for a second consecutive series win.
Oneil Cruz got things going for Pittsburgh in the first inning with a leadoff walk. He then stole second base for his National League-leading 19th stolen base of the season. Bryan Reynolds, scorching hot coming into today’s game, then came to the plate with a runner in scoring position and only one out.
Reynolds would walk as well. Spencer Horwitz then flew out to left, while Ke’Bryan Hayes grounded out to third base to end the Pirates early threat.
The Padres did not take long to open up the scoring. With two outs, Manny Machado blasted a no-doubt shot to left field off a hanging curveball from Pirates starting pitcher Andrew Heaney to give the Padres a 1-0 lead. It was Machado’s third home run off Heaney in 23 career at-bats against the lefty.
Jackson Merrill followed the home run with a double in the left-center gap. In the next at-bat, Gavin Sheets hit a ball to almost the exact same spot. But it had a little more loft than Merrill’s line-drive, and Cruz was able to soar over to the ball for the third out.
In the third inning, Cruz walked again. He also stole second again. It was his 20th stolen base of the season.
Cruz did not need to use his legs to score a run. Instead, Andrew McCutchen hammered a home run to left field, giving the Pirates a 2-1 lead.
The home run was McCutchen’s 240th as a Pittsburgh Pirate, tying him with legend Roberto Clemente for the third most in franchise history.
McCutchen’s moment came only two days after he moved into ninth place all-time on the Pirates’ leaderboard for hits.
Pittsburgh’s offense did not stop there. Spencer Horwitz hit a ground-rule double to left-center field. Then, Hayes drove him in with a soft single to center field. Hayes would ultimately be caught in a pickle, but the Pirates still left the top half of the third inning with a 3-1 lead.
Adam Frazier kept the offensive momentum going with a solo home run to lead off the fourth inning. It was Frazier’s third home run of the season, and the first opposite field home run of his ten-year career. After singles from Tommy Pham and Isiah Kiner-Falefa, Vasquez’s evening was over.
The right-hander pitched 3.1 innings, allowing six hits, four earned runs, while walking four and striking out three. It was Vasquez’s shortest start of the season.
Reliever Wandy Peralta came on and limited the damage. The Pirates now carried a 4-1 lead.
Heaney dominated the middle innings for the Pirates. He retired 13 Padres hitters in a row from the second to the sixth inning. Luis Arraez broke up the streak in the sixth with a one-out double down the left field line.
After giving up the Machado home run, Heaney was able to keep his breaking balls down and away from San Diego bats. His on-the-go adjustments made all the difference in another solid start for a Pirates starting pitcher.
The Padres scored their second run when Merrill notched his second double of the day, this one down the right-field line. The score now 4-2, Heaney was replaced by reliever Chase Shugart. He did not allow Merrill to score, his 12th stranded runner of the season. That’s the most of any reliever in MLB without allowing a stranded runner to score.
Heaney’s line for the day was 5.2 innings pitched, five hits allowed, two earned runs, with no walks and three strikeouts. It was a nice rebound from Heaney’s previous start against Arizona, his worst outing of the season.
San Diego took advantage of Heaney’s removal. In the seventh inning, Pirates reliever Tanner Rainey walked two batters before an Elias Diaz single put the Padres within one run. Then, Rainey walked Fernando Tatis Jr. to load the bases with only one out. Rainey’s short, unsuccessful outing was done after this. He walked three and allowed one hit.
Left-hander Caleb Ferguson came on to replace Rainey in the tough spot. Arraez proceeded to loop a RBI single past Kiner-Falefa to tie the game at 4-4, with the bases still loaded.
Machado then drove a ball into the left-center field gap that looked like might go over the wall for a grand slam. But it died at the warning track, and Cruz was able to snag the ball for the second out. Still, a Padres runner came around to score on the sacrifice fly, giving the Padres a 5-4 lead.
Tyler Wade provided the Padres a 6-4 lead when he hit a comebacker ground ball that bounced off Ferguson’s glove and died behind the mound. Ferguson struck out Xander Bogaerts to stop the bleeding.
All four runs that were allowed in the inning were credited to Rainey. His ERA rose to 10.57 after today’s appearance. He also took the loss today.
The Pirates’ bats went down in order during the eighth inning. Closer Robert Suarez came on to pitch the ninth for San Diego. He had no issues retiring the Pirates in order again, notching his 19th save of the season. He lowered his ERA on the season to 2.13.
The Pirates will return home for a three-game series against the Houston Astros that starts on Tuesday. They are off for a travel day on Monday. Paul Skenes (4-5, 2.15 ERA, 77 K) will take the mound for the Pirates on Tuesday night, while Lance McCullers Jr. (0-1, 5.89 ERA, 26 K) gets the starting nod for Houston. First pitch is expected at 6:40 PM ET.
Make sure to visit Pirates OnSI for the latest news, updates, interviews and insight on the Pittsburgh Pirates
Pittsburg, PA
Bike Share Pittsburgh celebrates 10 years in the city
Bike Share Pittsburgh is celebrating a milestone.
Saturday marked 10 years since launching bike stations across the city.
What originally started as “Healthy Ride” eventually turned into “POGOH.”
Officials say a majority of the bikes are fully-charged electric-assist bikes to help riders make their way from place to place.
They say they are glad to see investments being put toward things like better sidewalks and bike lanes.
“I do think that Pittsburgh can be a world-class biking city and we have a lot of people who are curious and just want to try it a couple times in the summer and that’s really cool too,” said David White, Executive Director of Bike Share Pittsburgh.
Over the past 10 years, Bike Share has served more than 150,000 riders with more than 1.5 million trips.
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