Pennsylvania
Penn expecting $467M windfall from COVID-19 vaccine royalty dispute
Penn Medicine researchers Katalin Karikó Ph.D., and Dr. Drew Weisman Ph.D., won the 2023 Nobel Prize in Medicine for their work on mRNA technology that contributed to the COVID-19 vaccine research.
Patents typically last about 20 years. The university holds at least four patents for its mRNA technology across the United States and Europe.
Researcher Karikó, an adjunct professor at Penn Medicine for 36 years, worked as a senior vice president for BioNTech between November 2013 and October 2022, according to her LinkedIn profile. She is considered an external consultant for the company as of Jan. 2, according to its website.
The COVID-19 vaccine, also known as Comirnaty, generated about $5 billion in sales in 2024.
As part of the deal, pharmaceutical giant Pfizer is expected to chip in $170 million for the Penn royalties and $364 million towards the NIH royalties owed.
As a company, BioNTech generated about $3.9 billion in revenue during 2023, down from $17.7 billion in 2022. BioNTech estimated 2024 revenue to be between $2.7 billion and $3.3 billion.
The university licensed its mRNA patents to several companies between April 2010 and August 2020, including Epicentre Technologies Corp., mRNA Biotherapeutics Inc. and Cellscript.
In 2017, BioNTech sublicensed the university mRNA technology from Cellscript and expects to keep developing more pharmaceutical medications, such as cancer treatments and flu vaccines, using the university patented technology.
Licensing revenue at the University of Pennsylvania has been a substantial revenue stream for the Philadelphia institution since the COVID-19 pandemic began.
In fiscal 2021, the university collected $300 million in license revenue. In fiscal years 2022 and 2023, the university garnered $1 billion each year. During fiscal year 2024, it reported $466 million in licensing revenue.
In May 2024, Penn Medicine researchers developed an mRNA vaccine for the H5N1 avian flu, leveraging prior COVID-19 vaccine research. The research was funded by the National Institute of Allergy and Infectious Diseases, National Institutes of Health and the Department of Health and Human Services.
The Duke University Human Vaccine Institute was awarded $7 million from the federal health agencies to conduct clinical trials in early 2025.
But for the commercialization of such research, the university relies on pharmaceutical manufacturers to license such patents and take the drug to market.
It was not immediately clear which companies, if any, have licensed the experimental avian flu technology.
Pennsylvania
Monday is the last day to register to vote in this month’s primary election in Pennsylvania
Monday, May 4, 2026 7:08PM
HARRISBURG, Pa. — Monday the last day to register to vote in this month’s primary election in Pennsylvania.
If you haven’t registered yet, you can do so in person at your county election office, or at a PennDOT facility along with other government agencies.
The last day to request a mail-in or absentee ballot is May 12th.
Those ballots must be received by your county elections office by 8 pm on May 19th which is primary day.
Polls will be open on May 19th from 7am until 8pm.
Pennsylvania has a closed primary system.
This means that Republican voters can vote only for Republican candidates and Democratic voters can vote only for Democratic candidates.
The U.S. has a new top amusement park – and it’s not Disney themed.
Little-known Knoebels Amusement Resort in Elysburg, Pennsylvania, took home the top prize for top amusement park in the recently released TripAdvisor “Best of the Best” list.
“Family-owned and operated since 1926, Knoebels Amusement Resort—located in Elysburg, Pennsylvania—is America’s largest free-admission amusement park. It’s got it all: roller coasters, kid-friendly rides (bumper cars, a haunted mansion), swimming, camping, a mining museum, and even a championship 18-hole golf course. The accommodating staff, clean facilities, and fun attractions make for a memorable family-friendly visit,” TripAdvisor noted.
The park, which is located in the middle of the state, received a 4.7 rating from nearly 3,000 reviewers on the website.
Dollywood, Disney World’s Magic Kingdom, Disney’s Hollywood Studios and Universal Island rounded out the top five on TripAdvisor’s list.
Knoebels celebrated taking the top spot with a social media post. Its fans were not surprised with the high ranking.
“We knew it all along,” the American Coaster Enthusiasts for Eastern Pennsylvania wrote in response.
“Been going since 1996,” one user wrote.
Knoebels opened in 1926 and is America’s largest free-admission park. Tickets for individual rides cost visitors a fee,, but entry remains free.
The resort offers more than 100 rides ranging from family to thrill coasters. The Impulse roller coaster is one of the park’s most popular and features upside-down twists and a 90-degree free fall. The Phoenix roller coaster is a classic wooden model that first opened in 1947 in Texas. In 1985 it was reborn at Knoebels.
If thrill seeking isn’t on your bucket list, the park offers plenty of gentler rides. The antique cars attractions let people drive a Model-T replica through the woods and under the Phoenix roller coaster. The park’s Grand Carousel also offers a throwback ride to users and a game on each ride where the winner gets a free turn.
Dolly Parton’s Dollywood in Tennessee took the second spot on the list.
“Dollywood is the brainchild of singer Dolly Parton, who grew up in the surrounding Smoky Mountains of Tennessee,” TripAdvisor noted. “The park has a downhome feel with singalongs and a museum dedicated to Parton’s life, plus high-velocity roller coasters and thrill rides. Watch artisans showcase glass blowing and pottery skills. Stay at the park’s two resorts for loads of perks.”
While a pair of Disney parks in Florida took the next two spots on the list.
“Known as The Most Magical Place On Earth, the Magic Kingdom Park needs no introduction. This theme park is located at the Walt Disney World Resort in Florida and features some of Disney’s best-known attractions (Space Mountain, Jungle Cruise, Cinderella Castle). There’s also a nightly fireworks show, musical parades, and meet and greets with your favorite Disney Characters,” TripAdvisor said of Magic Kingdom.
Here is the full top 10 list:
- Knoebels Amusement Resort (Elysburg, Pennsylvania)
- Dollywood (Pigeon Forge, Tennessee)
- Magic Kingdom Park (Bay Lake, Florida)
- Disney’s Hollywood Studios (Bay Lake, Florida)
- Universal Islands of Adventure (Orlando, Florida)
- Epcot (Bay Lake, Florida)
- Legoland California (Carlsbad, California)
- Universal Studios Florida (Orlando, Florida)
- Disneyland Park (Anaheim, California)
- Silver Dollar City (Branson, Missouri)
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