News
Hormones for menopause are safe, study finds. Here's what changed
Low-dose estrogen can be taken orally, but it’s also now available in patches, gels and creams.
svetikd/Getty Images
hide caption
toggle caption
svetikd/Getty Images
Low-dose estrogen can be taken orally, but it’s also now available in patches, gels and creams.
svetikd/Getty Images
The benefits of hormone therapy for the treatment of menopause symptoms outweigh the risks. That’s the conclusion of a new study published in the medical journal JAMA.
“Among women below the age of 60, we found hormone therapy has low risk of adverse events and [is] safe for treating bothersome hot flashes, night sweats and other menopausal symptoms, ” says study author Dr. JoAnn Manson, chief of preventive medicine at Brigham and Women’s Hospital. This is a departure from the advice many women have been given in the past.
The new analysis is based on two decades of follow-up data from the Women’s Health Initiative study, which followed thousands of women taking hormone replacement therapy. The study was halted after it was found that women taking Prempro, which is a combination of estrogen and progestin, had higher risks of breast cancer and stroke.
“The findings were surprising,” Manson says, pointing out that the reason the randomized trial was conducted was because scientists were trying to determine if hormone therapy decreased the risk of heart disease and other conditions.
After the initial findings came out, many women abruptly stopped the therapy. Prescriptions plummeted, and many healthcare providers still hesitate to recommend hormone therapy. But menopause experts say it’s time to reconsider hormone therapy, because there’s a lot known now that wasn’t known two decades ago.
Most significantly, there are now different types of hormones — delivered at lower doses — that are shown to be safer.
“Women should know that hormone therapy is safe and beneficial,” says Dr. Lauren Streicher, a clinical professor of obstetrics and gynecology at Northwestern University Feinberg School of Medicine.
Looking back, Dr. Streicher says, it’s clear the Women’s Health Initiative study was flawed and that some of the risks that were identified were linked to the type of hormones that women were given.
“We learned what not to do,” Streicher says. The type of progestin used, known as medroxyprogesterone acetate, was “highly problematic,” she says. This was likely responsible for the increase in breast cancer seen among women in the study. “So we don’t prescribe that anymore,” Streicher says.
Increasingly, other types of hormones are used, such as micronized progesterone which does not increase the risk of breast cancer, ” Streicher says. Micronized progesterone is a bioidentical hormone that has a molecular structure identical to the progesterone produced by womens’ ovaries, and tends to have fewer side effects.
Another problem with the study was the age of the women enrolled. Most of the women were over the age of 60, Streicher says .” And we know that there is a window of opportunity when it is the safest to start hormone therapy and that you get the most benefit.” That window is typically between ages 50 and 60, she says.
Another risk identified in the Women’s Health Initiative study, was an increased incidence of pulmonary embolism among women taking hormones. A pulmonary embolism is a blood clot that blocks blood flow to the lungs.
Since women in the study were taking estrogen orally, by pill, this may have increased their risk, Streicher says. A better option for people at risk of clots is to take estrogen through the skin, via a patch, a cream or gel.
“The advantage of a transdermal estrogen is that it is not metabolized by the liver,” Streicher says. “And because it’s not metabolized by the liver, we don’t see that increase in blood clots.”
With a range of hormone therapies available now, Dr Streicher says there’s not a one-size fits all approach. “Hormone therapy is beneficial way beyond the benefits to just helping with hot flashes,” she says. Ongoing research points to protection against bone loss and heart disease, too.
Streicher says women should talk to their healthcare providers about what options may best suit their needs.
This story was edited by Jane Greenhalgh
News
Judge says she won’t halt the immigration enforcement surge as a lawsuit proceeds
A photo of Renee Good is displayed in front of a home on Saturday, Jan. 31, 2026, in Minneapolis.
Alex Brandon/AP
hide caption
toggle caption
Alex Brandon/AP
MINNEAPOLIS — A federal judge says she won’t halt the immigration enforcement surge in Minnesota and the Twin Cities as a lawsuit over it proceeds.
Judge Katherine M. Menendez on Saturday denied a preliminary injunction sought in a lawsuit filed this month by state Attorney General Keith Ellison and the mayors of Minneapolis and St. Paul.
It argued that the Department of Homeland Security is violating constitutional protections. The lawsuit sought a quick order to halt the enforcement action or limit its scope. Lawyers with the U.S. Department of Justice have called the lawsuit “legally frivolous.”
The ruling on the injunction focused on the argument by Minnesota officials that the federal government is violating the Constitution’s 10th Amendment, which limits the federal government’s powers to infringe on the sovereignty of states. In her ruling, the judge relied heavily on whether that argument was likely to ultimately succeed in court.
The federal government argued that the surge, dubbed Operation Metro Surge, is necessary in its effort to take criminal immigrants off the streets and because federal efforts have been hindered by state and local “sanctuary laws and policies.” State and local officials argued that the surge is retaliation after the federal government’s initial attempts to withhold federal funding to try to force immigration cooperation failed.
“Because there is evidence supporting both sides’ arguments as to motivation and the relative merits of each side’s competing positions are unclear, the Court is reluctant to find that the likelihood-of-success factor weighs sufficiently in favor of granting a preliminary injunction.”

U.S. Attorney General Pam Bondi took to social media Saturday to laud the ruling, calling it “another HUGE” legal win for the Justice Department on X.
Federal officers have fatally shot two people on the streets of Minneapolis: Renee Good on Jan. 7 and Alex Pretti on Jan. 24.
News
Anti-ICE protests take place across US for ‘National Shutdown’
Local businesses across the US forwent income for the day to protest the Trump administration’s immigration crackdown and the fatal shooting of Renee Good and Alex Pretti by federal agents in Minneapolis.
In what was billed a “National Shutdown,” organizers called for a 24-hour general strike, asking students to skip school, business owners to close up shop, and consumers to refrain from spending for the day.
Some small and medium-sized businesses from coast to coast posted on their social media stating that they’d be closed on Friday as part of the demonstrations. Others said that they’d remain open to support their workers, but showed support for the protests.
Touchstone Climbing, a popular California-based climbing gym with about 20 locations, posted on social media that its gyms were closed and that hourly employees scheduled to work on Friday would be paid.
Spencer Platt/Getty Images
Medium, an online publishing company, told employees that they were free to take Friday off to participate in the protests.
Photos show crowds of demonstrators holding signs that said “ICE Out” and gathering in Los Angeles, Washington, DC, New York City, Boston, and Minneapolis, among other cities.
The protests come amid growing tensions in communities where the Trump administration has deployed federal agents. Many of the high-profile enforcement efforts have been concentrated in blue or so-called sanctuary cities.
In Minneapolis, two US residents, Good and Pretti, were fatally shot after a confrontation with federal agents that occurred within a span of a few weeks.
John Moore/Getty Images
Hundreds of local businesses in Minnesota participated in an economic blackout last week, shuttering their stores for a day following the shootings. The Minneapolis Regional Labor Federation, which is tied to AFL-CIO, the largest labor union in the US, endorsed the general strike.
The Department of Justice announced on Friday that it opened a civil rights investigation into the shooting of Pretti, a 37-year-old registered nurse who was killed by a Border Patrol agent.
News
Map: 2.4-Magnitude Earthquake Reported in New Jersey
Note: Map shows the area with a shake intensity of 3 or greater, which U.S.G.S. defines as “weak,” though the earthquake may be felt outside the areas shown. The New York Times
A minor, 2.4-magnitude earthquake struck in New Jersey on Friday, according to the United States Geological Survey.
The temblor happened at 3:42 p.m. Eastern about 4 miles northeast of Whitehouse Station, N.J., or about 35 miles west of Manhattan, data from the agency shows.
As seismologists review available data, they may revise the earthquake’s reported magnitude. Additional information collected about the earthquake may also prompt U.S.G.S. scientists to update the shake-severity map.
Source: United States Geological Survey | Notes: Shaking categories are based on the Modified Mercalli Intensity scale. When aftershock data is available, the corresponding maps and charts include earthquakes within 100 miles and seven days of the initial quake. All times above are Eastern. Shake data is as of Friday, Jan. 30 at 3:59 p.m. Eastern. Aftershocks data is as of Friday, Jan. 30 at 5:58 p.m. Eastern.
-
Illinois1 week agoIllinois school closings tomorrow: How to check if your school is closed due to extreme cold
-
Pennsylvania6 days agoRare ‘avalanche’ blocks Pennsylvania road during major snowstorm
-
Technology1 week agoRing claims it’s not giving ICE access to its cameras
-
Tennessee18 hours agoUPDATE: Ohio woman charged in shooting death of West TN deputy
-
News1 week agoVideo: Jack Smith Defends His Trump Indictments During House Hearing
-
Movie Reviews5 days agoVikram Prabhu’s Sirai Telugu Dubbed OTT Movie Review and Rating
-
Politics1 week agoWhite House explains bruise on Trump’s hand
-
Politics6 days agoTrump’s playbook falters in crisis response to Minneapolis shooting