Illinois
Higher acetaminophen intake in pregnancy linked to attention deficits in young children
CHAMPAIGN, Ill. — A new study links increased use of acetaminophen during pregnancy – particularly in the second trimester – to modest but noticeable increases in problems with attention and behavior in 2-, 3- and 4-year-olds. The study adds to a growing body of evidence linking the frequent use of acetaminophen in pregnancy to developmental problems in offspring.
The findings are detailed in the journal Neurotoxicology and Teratology.
The research is part of the Illinois Kids Development Study at the University of Illinois Urbana-Champaign, which explores how environmental exposures influence child development. The study tracked hundreds of children, collecting data on their prenatal chemical exposures and asking caregivers to assess their behaviors and traits at ages 2, 3 and 4.
While acetaminophen is considered the safest painkiller and fever reducer available during pregnancy, previous studies have found evidence of a range of possible negative outcomes for children exposed to the drug in gestation, said Megan Woodbury, who led the research as a graduate student at the U. of I. with comparative biosciences professor emerita Susan Schantz, the principal investigator of the IKIDS program at Illinois. Woodbury is now a postdoctoral researcher at Northeastern University in Boston. Schantz is a faculty member of the Beckman Institute for Advanced Science and Technology at the U. of I.
A recent study led by Woodbury and Schantz linked higher acetaminophen exposure in pregnancy to language delays in children.
Some previous studies have found no relationship between acetaminophen use in pregnancy and attention and behavior in childhood, while other, usually larger studies found relationships between more frequent use of the medication during pregnancy and attention-related and behavioral problems in offspring. Most of the latter studies were conducted in older children and questioned pregnant participants about their use of acetaminophen at most once per trimester. The new study asked pregnant parents about their acetaminophen use six times over the course of the pregnancy – roughly once every four-to-six weeks – offering a more precise picture of the magnitude and timing of the drug exposures.
The researchers also asked caregivers to answer dozens of standardized questions about their child’s behavior and ability to pay attention at ages 2, 3 and 4. More than 300 children were assessed at age 2, with 262 assessed again at 3, and 196 at age 4.
“Our most important finding was that with increasing acetaminophen use by pregnant participants, especially during the second trimester, their children showed more attention-related problems and ADHD-type behaviors, which we call ‘externalizing behaviors,’ at every age we measured,” Woodbury said.
“The kinds of behaviors the caregivers reported included things like the child talking out of turn, not paying attention, not being quiet when they were supposed to be quiet, not sitting down when they were supposed to be sitting down, and being a little aggressive with other children,” Schantz said.
The findings are not an indication that the children have attention-deficit/hyperactivity disorder or that they will be diagnosed with ADHD at a later date, Schantz said. But the children seem to be having more trouble with attention than peers of the same age who were less exposed or not exposed to acetaminophen in the womb.
Woodbury, who herself is pregnant, says she does not want to scare others away from using acetaminophen in pregnancy when needed. Extreme headaches or other painful episodes and fevers can be debilitating and even dangerous, calling for use of the drug. She said she has turned to acetaminophen once per trimester so far. But she also chooses not to use it for minor aches, pains or slight fevers.
More research is needed to test whether more frequent use of acetaminophen during the second trimester of pregnancy may be particularly problematic for the developing brain, the researchers said. The study also is limited as participants were mostly white, non-Hispanic and of higher economic status. Schantz and her team are working to broaden the cohort of participants in IKIDS to include pregnant people from a greater diversity of social, economic and racial backgrounds.
This research was supported by the Children’s Environmental Health and Disease Prevention Research Center funded by the National Institute of Environmental Health Sciences and the U.S. Environmental Protection Agency and the National Institutes of Health Environmental Influences on Child Health Outcomes program.
Illinois
Advocates, opponents seek to sway Gov. JB Pritzker on medical aid in dying legislation passed by Illinois General Assembly
Illinois could soon join a growing list of states where terminally ill patients would be allowed to take life-ending medication prescribed by a doctor.
The Illinois Senate narrowly approved the “medical aid in dying” legislation in October, after the Illinois House passed it in May, and the legislation is now sitting on Gov. JB Pritzker’s desk.
Pritzker has not said if he’ll sign it, and the controversial legislation has people on both sides trying to bend the governor’s ear.
Medical aid in dying, also called assisted suicide or dying with dignity, is legal in 12 states, with eight others considering similar legislation.
If Pritzker allows the “End-of-Life Options for Terminally Ill Patients Act” passed by the Illinois General Assembly to become law, Illinois could be the first state in the Midwest to allow medical aid in dying.
Suzy Flack, whose son Andrew died of cancer, is among the advocates urging the governor to sign the bill.
Diagnosed with terminal cancer in 2017 in his home state of Illinois, three years later Andrew moved to California, where medical aid in dying is legal, and chose to end his life in 2022.
“He died on his own terms, peacefully. We were all there to see it and embrace him at that moment, and it was really a beautiful thing,” Suzy said. “His last words were, ‘I’m happy. Please sign this. Allow people in Illinois this option.’”
Illinois is on the brink of joining a growing number of states that allow doctors to prescribe a mixture of lethal medication for terminally ill patients.
Outside the governor’s Chicago office on Thursday, many disability advocates, religious leaders, lawmakers, and doctors have called on Pritzker to veto the bill that would legalize what they call state-sanctioned suicide
“The question becomes where do you draw the line in the medical ethics dilemmas?” one physician who identified himself as Dr. Pete said. “We don’t need to go to this crossing of a red line of actually providing a means to directly end life.”
Republican Illinois state Sen. Chris Balkema said he “would really appreciate it if the governor would veto this bill.”
“My plea is that we veto this; come back with language that is constructive on both sides,” he said.
Pritzker has he is reviewing the legislation and is listening to advocates on both sides before deciding whether to sign it.
“It’s a hard issue, and I don’t want anybody to think making up your mind about this is very easy. It’s not. There’s a lot to consider, but most of all it’s about compassion,” he said. “There’s evidence and information on both sides that leads me to think seriously about what direction to go.”
The Illinois legislation would require two doctors to determine that a patient has a terminal disease and will die within six months. The medication provided to terminally ill patients would need to be requested both orally and in written form, and would have to be self-administered.
The bill was sent to Pritzker on Nov. 25, and he has 60 days from then to either sign it, amend it and send it back to lawmakers, veto it, or allow it to become law without his signature.
Illinois
Two rounds of snow on the way to central Illinois – IPM Newsroom
Snow is making a comeback in Central Illinois.
IPM meteorologist Andrew Pritchard said A Winter Weather Advisory is in effect for Champaign County and surrounding portions of east-central Illinois beginning Thursday at 3:00 p.m. to Friday at 6:00 a.m.
Snow will spread into Champaign-Urbana between 3-6 PM late this afternoon into the evening with periods of moderate to heavy snowfall continuing overnight. Snow should taper off around sunrise on Friday morning, with around 2-4″ of new snow accumulation expected across Champaign County.
Winds will blow out of the east around 5-10 mph, with minimal impacts from blowing & drifting snow. Still, snow accumulation on roadways could lead to hazardous travel conditions overnight into the Friday morning commute.
On Saturday, the National Weather Service in Central Illinois forecasted for snow to return on Saturday afternoon. The chance of precipitation is 80%. New snow accumulation of 2 to 4 inches possible. Temperatures will drop below zero across much of central Illinois both Saturday night and Sunday night with resulting wind chill values as cold as 15 to 30 below zero.
Illinois
Woman facing charges 5 years after infant’s remains found in north suburbs, police say
RIVERWOODS, Ill. (WLS) — A woman is facing charges five years after the discovery of a dead newborn in the north suburbs.
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Riverwoods, Illinois police say Natalie Schram gave birth to the baby in May 2020 and then dumped the baby’s body in a wooded area in the 1800 block of Robinwood Lane.
Schram was arrested earlier this month in Washington State and has now bee charged in connection to the crime, police said.
SEE ALSO | 2 charged after infant’s remains found buried at Wilmington home, Will County sheriff says
The suspect is expected to appear in a Lake County, Illinois courtroom on Thursday.
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