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Three women — ages 41, 55 and 64 — share their secrets to better health and longevity

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Three women — ages 41, 55 and 64 — share their secrets to better health and longevity

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For an increasing number of women over 40, age really is just a number.

It may not be possible to stop the passage of time — but certain healthy habits can help slow down biological age, experts say.

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“As we age, our abilities to perform certain physical and cognitive tasks decline, while our risks for disease and ultimately death increase,” Chris Mirabile, CEO and founder of NOVOS, a longevity supplements company in New York, told Fox News Digital.

“Although these changes are correlated with chronological age, biological age is a more accurate predictor, because it looks at individuals and how well – or poorly – they are aging.”

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If a 40-year-old woman has a biological age of 35, it implies that she is biologically in the same place as an average 35-year-old, Mirabile said – which means a significant reduction in risk for disease and death, plus an increased capacity for activities associated with a high quality of life.

Left to right, Julie Gibson Clark, Amy Hardison and Lil Eskey shared the lifestyle habits that help them slow down biological aging. (James Lee; Amy Hardison; Lil Eskey)

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For Women’s Health Month, three mothers at three different stages of life shared how they are defying age through simple lifestyle practices and interventions.

The women all participated in a six-month-long trial of NOVOS Core and Boost, supplements that are designed to slow down the aging process. Over the course of the study, they took three epigenetic tests, which analyzed DNA via a small blood sample to measure their “pace of aging.”

Lil Eskey, 41 years old, still has young kids

Lil Eskey, 41, is a stay-at-home mom and former fitness instructor in Phoenix, Arizona.

Growing up, she frequently had allergies and a constant sore throat. 

“The way that my mom handled it was to put me on antibiotics so many times when I was a kid,” she told Fox News Digital. 

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Lil Eskey, 41, pictured with her son, is a stay-at-home mom and former fitness instructor in Phoenix, Arizona. Maintaining a more youthful energy level is important to Eskey, as she is still raising young children. (Lil Eskey)

“I also had gut issues most of my life, so my path into health and wellness stemmed from trying to figure out what was going on with my body.”

Prioritizing her sleep is the biggest thing Eskey does for her health, she told Fox News Digital. 

“Good sleep is so underrated,” she said.

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“Having a consistent bedtime and wake-up time is so important for overall wellness. Everything works so much better when you’re well-rested, including any stressors in your life or anything going on with the mind.”

Eskey also tries to incorporate movement into her life wherever possible. 

“When my son goes to preschool, I pull him on a bike trailer. The same goes for anything that’s a few miles away, like grocery shopping.”

“I want to be completely present for my kids and maintain a level of energy and vitality in life.”

After dinner, the family often goes out on bike rides or jumps on the trampoline. 

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“We do anything to make it fun,” she said.

When it comes to mental health, Eskey has made the decision not to use social media.

Pictured on a hike, Eskey said she incorporates movement into her life wherever possible.  (Lil Eskey)

“I hear about anything that’s super important, and I’ll check the news occasionally to see what information I need, but to me, social media just seems like an additional stressor on the body,” she said. 

Eskey and her family often experiment with different health practices, she said. 

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“I listen to different podcasts on health and fitness to hear about new science or new ideas, and then we’ll test it out to see what works,” she said. 

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“For example, I realized I feel way better when I have a couple of hours between having my last meal and going to bed.”

She’s also experimented with using a continuous glucose monitor to track her blood sugar.

“We’re always just doing different experimental things to see what makes the biggest change,” Eskey said.

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Prioritizing her sleep is the biggest thing Eskey does for her health, she told Fox News Digital. “Good sleep is so underrated,” she said. (Photo Illustration by Ute Grabowsky/Photothek via Getty Images)

She has also been using anti-aging supplements from NOVOS. During the course of the study, Eskey’s biological pace of aging was reduced from .99 to .77.

“The time we’re here on this earth doesn’t always have to reflect the cumulative stress on our bodies. Rather, it’s stress that causes aging,” she said. 

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“It’s more important now than ever, with all the toxins and stressors we’re facing.”

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Maintaining a more youthful energy level is important to Eskey, as she is still raising young children, she said.

“The biggest thing is being able to keep up with my kids and be totally active,” Eskey said.  (Lil Eskey)

“The biggest thing is being able to keep up with my kids and be totally active,” she said. 

“When my kids want to play at the park, it’s important to me that I’m not just sitting on the bench watching them. I want to be completely present for my kids and maintain a level of energy and vitality in life.”

Julie Gibson Clark, 55 years old, focuses on movement

A recruiter who lives in Phoenix, Arizona, Julie Gibson Clark said she focuses on seven key areas to help slow down biological aging.

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The first is movement, both strength and cardio. “I focus on full-body strength training twice per week and a mix of zone 2 and Vo2Max training the rest of the week,” she told Fox News Digital.

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In her diet, Clark focuses heavily on veggies.

“I mix cooked greens and veggies, about 1 pound total every day,” she said. “I started small (about 4 ounces) and added about 1 ounce per week.”

Clark also prioritizes 90 to 100 grams of healthy protein each day: a mix of vegan protein, collagen and healthy, pasture-raised meats and eggs.

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Julie Gibson Clark, a recruiter who lives in Phoenix, Arizona, said she focuses on seven key areas to help slow down biological aging. (Julie Gibson Clark)

Sleep is also a big priority for Clark. “It’s hard to perform well at anything without proper sleep,” she told Fox News Digital.

Saunas and cold showers are another part of Clark’s regular routine. “This is my natural antidepressant and helps with focus during the day,” she said. “For anyone struggling with low mood or stressful times, I highly recommend trying this.”

Clark also began meditating in 2019, which she described as “a game-changer for stress and sleep.” 

“I like to think of longevity practices like a braid with three strands — exercise, eating right and prioritizing sleep.”

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“Twenty minutes every afternoon improves my sleep and allows me to recalibrate stress levels during the day,” she said.

Clark also takes NOVOS supplements, which she credits with increasing her energy levels and slowing her pace of aging by 8%, according to the study results.

“When you start moving, you’ll likely be more motivated to eat well, and your sleep will be better. When you sleep, it’s easier to stay on track with your diet and fitness plans,” Clark said. “They all work together.” (James Lee)

“I like to think of longevity practices like a braid with three strands — exercise, eating right and prioritizing sleep,” she told Fox News Digital. “And there’s an extra colorful strand in there: supplements. Each of these works together to help the others.”

She added, “When you start moving, you’ll likely be more motivated to eat well, and your sleep will be better. When you sleep, it’s easier to stay on track with your diet and fitness plans. They all work together.”

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Clark said she adheres to the motto, “It’s not the years in your life, but the life in your years.”

“I want all the years I have to be full of mobility, vibrance and vitality.”

Amy Hardison, 64 years old, makes exercising fun

A writer and grandmother of 11 in Mesa, Arizona, Amy Hardison has always had consistent health and exercise habits.

“I have exercised aerobically an hour a day, six days a week for 50 years and have rarely missed a day,” she told Fox News Digital. 

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“I always listen to an audiobook while exercising, making it even more fun.”

Amy Hardison’s favorite exercises include swimming and working out on the elliptical. “I love working out at home — other people love going to a gym and having a trainer. Do whatever works for you and then do it consistently,” she advised. (Amy Hardison)

Hardison’s favorite exercises include swimming and working out on the elliptical. 

“I love working out at home — other people love going to a gym and having a trainer. Do whatever works for you and then do it consistently,” she advised.

Regarding nutrition and exercise, Hardison’s philosophy is to find something you love that you can stick with long-term. 

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“Aging will take you places you have never been.”

“Some people totally cut out sugar from their diet, often because they tend to eat too much once they start,” she said. “Others, like me, eat small amounts each day.”

Hardison had never been into vitamins and supplements until she got involved in the NOVOS study.

“I really liked that the study included bloodwork at the beginning, middle and end of the year-long trial,” she said. 

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“My bloodwork revealed that at the beginning of the study, I was aging at .86 biological years for every chronological year.  At the end of the study, I was aging at .74. That is compelling empirical data.”

Although Hardison does what she can to stay physically healthy and mentally sharp, she acknowledges that there is a limit to what she can control. 

“Life is to be lived and enjoyed,” said Hardison, pictured hiking with her husband. (Amy Hardison)

“There is even a limit to how much I am willing to invest in longevity,” she said. “Life is to be lived and enjoyed.”

“Aging will take you places you have never been,” Hardison continued. 

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“There is so much to learn and experience. Embrace the normal and natural decline with humor and perspective. Thank your body for taking you on the journey.”

A biohacker’s 5 quick tips for healthy aging

Melanie Avalon, health influencer, entrepreneur and host of The Intermittent Fasting Podcast and “The Melanie Avalon Biohacking Podcast,” agreed that women can take proactive steps to slow their pace of aging.

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“The ever-growing online bloodwork and genetic platforms allow women access to personal data, providing a deeper view of their aging on a cellular level, including monitoring their biological age, which may differ from their chronological age,” she told Fox News Digital. 

“Women can then make dietary and lifestyle choices to optimize these markers.”

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1. Optimize sleep

One of the biggest issues aging women experience is restless sleep, often characterized by tossing, turning and hot flashes, according to Avalon.

One of the biggest issues aging women experience is restless sleep, often characterized by tossing, turning and hot flashes, according to Avalon. (iStock)

“Women can implement a ‘sleep sanctuary’ to best support a restorative night, including sticking to a consistent wind-down routine and sleep schedule, in a cool, dark environment,” she advised.

Using a cooling mattress, avoiding late-night blue light exposure, and finding the optimal sleep position are some ways women can achieve better sleep quality, Avalon advised.

2. Seek hormonal support as needed

“Women often dread the perimenopausal years for their seemingly inevitable rollercoaster of hormonal issues,” Avalon said.

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“Women can support healthy hormonal levels and natural transitions into the menopausal years by nourishing their bodies with micronutrient-rich whole foods, getting ample sleep, addressing stress levels, and reducing their exposure to toxins.”

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For some women, hormone replacement therapy may be an option.

“Many women may find that the benefits outweigh the risks,” Avalon noted.

3. Optimize muscle mass

Maintaining muscle mass is crucial for healthy aging, according to Avalon. 

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“Declines in muscle mass and strength are intrinsically tied to mortality, playing a causative role in falls and metabolic issues,” she said. 

The maintenance of muscle mass is crucial for healthy aging, according to one expert. (iStock)

“Aging typically leads to reduced muscle protein synthesis,” Avalon noted.

“Women should pay careful attention to getting ample protein as they age, with a particular focus on the amino acid leucine, which stimulates muscle protein synthesis.” 

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Aging women should aim for a gram of protein per pound of body weight, Avalon recommended. 

“Women can also engage in strength training to further support muscle growth and maintenance,” she added.

4. Monitor essential markers

“Aging women should embrace the agency to take their health into their own hands,” Avalon said.

Women should work with conventional doctors to regularly check key health metrics, such as blood pressure, blood sugar levels, cholesterol and bone density, along with other markers of disease, an expert advised. (iStock)

She recommends working with conventional doctors to regularly check key health metrics, such as blood pressure, blood sugar levels, cholesterol and bone density, along with other markers of disease.

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5. Achieve proper glycemic control

Poor glycemic control is linked to a myriad of degenerative diseases, from prediabetes and diabetes to cardiovascular disease and cognitive decline, according to Avalon. 

“Aging women can implement an unprocessed, whole-food-based diet, low to moderate in carbs, depending on their tolerance,” she said. 

Women can also opt to wear a continuous glucose monitor (CGM) to monitor their blood sugar levels.

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Health

Do collagen supplements really improve skin? Major review reveals the truth

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Do collagen supplements really improve skin? Major review reveals the truth

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Collagen supplements have exploded in popularity, touted as everything from an anti-aging miracle to a muscle recovery booster.

But a sweeping new review conducted by U.K. researchers suggests that while collagen may help improve skin elasticity and ease arthritis pain, it does little for athletic performance or wrinkle reduction.

Researchers from Anglia Ruskin University analyzed 16 systematic reviews and 113 randomized controlled trials involving nearly 8,000 participants worldwide, which they say is the most extensive evaluation of collagen’s health effects to date. 

The review found consistent evidence that collagen supplementation improves skin elasticity and hydration over time and provides significant relief from osteoarthritis-related joint pain and stiffness, according to findings published in Aesthetic Surgery Journal Open Forum. 

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A large U.K. review found that collagen supplements may improve skin elasticity and hydration over time. (iStock)

The researchers, however, did not find meaningful improvements in post-exercise muscle recovery, soreness or tendon mechanical properties (strength, springiness and stretch resistance).

“Collagen is not a cure-all, but it does have credible benefits when used consistently over time, particularly for skin and osteoarthritis,” co-author Lee Smith, professor of public health at Anglia Ruskin University, said in a statement.

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“Our findings show clear benefits in key areas of healthy aging, while also dispelling some of the myths surrounding its use,” Smith added.

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Collagen, the most abundant protein in the body, supports skin, bones, tendons, cartilage and connective tissue, according to experts. Natural collagen production begins to drop in early adulthood and declines more sharply with age.

The study found that collagen supplements may help reduce joint pain and stiffness in people with osteoarthritis. (iStock)

The review found that long-term collagen supplementation was linked to improved skin firmness and hydration, but did not help skin roughness — a proxy for visible wrinkles. 

Benefits appear to accumulate gradually, suggesting that collagen should not be viewed as an “anti-wrinkle ‘quick fix,’ but as a foundational dermal support for individuals seeking holistic skin maintenance,” the researchers said.

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“If we define anti-aging as a product or technique designed to prevent the appearance of getting older, then I believe our findings do support this claim for some parameters,” Smith told the BBC. “For example, an improvement in skin tone and moisture is associated with a more youthful-looking appearance.”

Collagen supplementation was linked to reduced pain and stiffness in people with osteoarthritis, with stronger benefits seen over longer periods of use, and showed modest improvements in muscle mass and tendon structure that may support healthy aging. 

Collagen did not significantly improve skin roughness, a marker of visible wrinkles. (iStock)

However, it did not show meaningful results when used as a fast-acting sports performance supplement, and evidence for benefits related to cholesterol, blood sugar, blood pressure and oral health was mixed or inconclusive.

Dr. Daniel Ghiyam, a California-based physician and longevity specialist, said the findings align with what he sees in clinical practice.

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“Collagen is a targeted support tool, not a foundation of health or performance,” Ghiyam, who was not involved in the study, told Fox News Digital. “When marketed that way, it makes sense. When marketed as a cure-all, it doesn’t hold up to the data.”

The authors noted that while many previous collagen studies have received financial support from the supplement industry, the current review did not receive industry funding.

Experts say collagen supplements may offer modest benefits for skin hydration and joint comfort, but they are not a cure-all. (iStock)

The team called for more high-quality clinical trials examining long-term outcomes, optimal dosages and differences between collagen sources, such as marine, bovine and plant-based alternatives. 

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Among its limitations, the review could not determine whether certain forms of collagen work better than others or what the optimal regimen should be. 

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While the review included randomized controlled trials, the quality of the studies varied, with newer research generally showing stronger results.

Experts say more data and studies are needed to build on the findings. They also noted that diet plays a crucial role in skin health.

Collagen supplements, often sold as powders or pills, may improve skin elasticity and ease joint pain, experts say. (iStock)

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Dr. Erum Ilyas, a Pennsylvania-based dermatologist and chair of dermatology at Drexel University College of Medicine, noted that the review analyzed previously published meta-analyses rather than generating new primary data.

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“At this time, I have not seen sufficiently strong independent evidence to routinely recommend collagen supplements to my patients,” Ilyas, who was not involved in the review, told Fox News Digital.

“Although some studies show modest improvements in markers such as hydration and elasticity, there remains limited independent, biopsy-confirmed evidence demonstrating sustained increases in dermal collagen content,” she added.

Fox News Digital has reached out to the researchers for comment.

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Origin of deadly cancer affecting young adults revealed in alarming report

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Origin of deadly cancer affecting young adults revealed in alarming report

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As colorectal cancer (CRC) is now the leading cause of cancer death in adults under 50, a new report reveals some surprising shifts in the incidence of the disease.

Although rates of CRC have been declining among seniors, those 65 and under are facing a rise in diagnoses, according to a report titled Colorectal Cancer Statistics, 2026, from the American Cancer Society.

Adults 65 and younger comprise nearly half (45%) of all new colorectal cancer cases — a significant increase from 27% in 1995, states the report, which was published in CA: A Cancer Journal for Clinicians.

The disease is rising fastest among adults 20 to 49 years old, at a rate of 3% per year.

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Colorectal cancer is now the leading cause of cancer death in adults under 50. (iStock)

Among adults 50 and under, 75% of colorectal cancers are diagnosed at an advanced stage. Half of the diagnoses in that age range are made between the ages of 45 and 49. Although that age group is eligible to receive routine screenings, just 37% do so.

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The report also revealed that rectal cancer is on the rise, now accounting for about one-third (32%) of all CRC cases — an increase from 27% in the mid-2000s.

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“After decades of progress, the risk of dying from colorectal cancer is climbing in younger generations of men and women, confirming a real uptick in disease because of something we’re doing or some other exposure,” said Rebecca Siegel, senior scientific director, surveillance research at the American Cancer Society and lead author of the report, in a press release.

Among adults 50 and under, 75% of colorectal cancers are diagnosed at an advanced stage. Half of the diagnoses in that age range are made between the ages of 45 and 49.  (iStock)

“We need to redouble research efforts to understand the cause, but also circumvent deaths through earlier detection by educating clinicians and the general public about symptoms and increasing screening in people 45-54 years.”

It is projected that 158,850 new cases of colorectal cancer will be diagnosed this year, and that the disease will cause 55,230 deaths, per the report.

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More than half of CRC cases can be linked to high-risk behaviors, the researchers said. Those include lack of nutrition, high alcohol consumption, smoking, lack of exercise and obesity.

“These findings further underscore that colorectal cancer is worsening among younger generations and highlight the immediate need for eligible adults to begin screening at the recommended age of 45,” said Dr. William Dahut, chief scientific officer at the American Cancer Society.

When the disease is caught at a local (early) stage, the five-year survival rate is 95%. (iStock)

“The report also shines a light on the crucial importance of continued funding for research to help discover new therapies to treat the disease and advance patient care.”

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When the disease is caught at a local (early) stage, the five-year survival rate is 95%, the report stated.

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Aging process could accelerate due to ‘forever chemicals’ exposure, study finds

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Aging process could accelerate due to ‘forever chemicals’ exposure, study finds

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A new study suggests that middle-aged men may be more vulnerable to faster biological aging, potentially linked to exposure to “forever chemicals.”

The research, published in the journal Frontiers in Aging, examined how perfluoroalkyl and polyfluoroalkyl substances, more commonly known as PFAS, could impact aging at the cellular level.

PFAS are synthetic chemicals commonly used in nonstick cookware, food packaging, water-resistant fabrics and other consumer products, the study noted. 

Their chemical structure makes them highly resistant to breaking down, allowing them to accumulate in water, soil and the human body.

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Chinese researchers analyzed blood samples from 326 adults enrolled in the U.S. National Health and Nutrition Examination Survey between 1999 and 2000.

A new study suggests that middle-aged men could face accelerated biological aging at the cellular level due to exposure to PFAS. (iStock)

The researchers measured levels of 11 PFAS compounds in participants’ blood and used DNA-based “epigenetic clocks” — tools that analyze chemical changes to DNA to estimate biological age — to determine how quickly their bodies were aging at the cellular level, the study stated.

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Two compounds, perfluorononanoic acid (PFNA) and perfluorooctanesulfonamide (PFOSA), were detected in 95% of participants.

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Higher concentrations of those chemicals were associated with faster biological aging in men of certain age groups, but not in women.

“People should not panic.”

The compounds most strongly linked to accelerated aging were not the PFAS chemicals that typically receive the most public attention, the researchers noted.

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“The associations were strongest in adults aged 50 to 64, particularly in men,” Dr. Xiangwei Li, professor at Shanghai Jiao Tong University School of Medicine and the study’s corresponding author, told Fox News Digital. 

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“While this does not establish that PFAS cause aging, it suggests that these widely present ‘forever chemicals’ may be linked to molecular changes related to long-term health and aging.”

The study found that two of the compounds were detected in 95% of participants, and higher levels were linked to faster biological aging in men ages 50–64. (iStock)

Midlife may represent a more sensitive biological period, when the body becomes more vulnerable to age-related stressors, according to the researchers.

Lifestyle factors, such as smoking, may influence biological aging markers, potentially increasing vulnerability to environmental pollutants.

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While Li said “people should not panic,” she does recommend looking for reasonable ways to reduce exposure. 

That might mean checking local drinking water reports, using certified water filters designed to reduce PFAS, and limiting the use of stain- or grease-resistant products when alternatives are available.

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Meaningful reductions in PFAS exposure will likely depend on broader regulatory action and environmental cleanup efforts, Li added.

The researchers noted that midlife could be a particularly sensitive stage, when the body is more susceptible to stressors associated with aging. (iStock)

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Study limitations

The researchers outlined several important limitations of the research, including that the findings show an association, but do not prove that PFAS directly causes accelerated aging.

“The study is cross-sectional, meaning exposure and aging markers were measured at the same time, so we cannot determine causality,” Li told Fox News Digital.

The study was also relatively small, limited to 326 adults age 50 or older, which means the findings may not apply to younger people or broader populations.

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Researchers measured PFAS levels using data collected between 1999 and 2000, and today’s exposure patterns may differ.

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Li added that while PFAS is known to persist in the environment and the body, these results should be validated through larger, more recent studies that follow participants over time.

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