Health
‘Smart mask’ could detect asthma, COPD and other medical conditions, researchers say
Your breath could hold clues to your health, researchers say — and they have developed a “smart mask” to tap into them.
Wei Gao, professor of medical engineering at the California Institute of Technology (Caltech) in Pasadena, led the team that created the EBCare, a mask that analyzes the chemicals in someone’s breath to detect any existing health issues.
The mask is designed to screen for medical conditions like respiratory infections, COPD (chronic obstructive pulmonary disease), asthma and post-COVID infections, according to a press release from Caltech.
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EBCare works by cooling the breath to convert it into a liquid, then transports it to sensors to be analyzed for specific biomarkers.
Researchers have developed a “smart mask” (pictured at left) to detect signs of medical conditions. (Caltech/Wei Gao and Wenzheng Heng; iStock)
In an email to Fox News Digital, lead researcher Gao noted the mask’s ability to enable “continuous, real-time monitoring of exhaled breath condensate (EBC) in a non-invasive and wearable format.”
“This technology has the potential to revolutionize the way we monitor respiratory health by providing valuable insights into conditions like asthma, COPD and other metabolic disorders,” Gao said, noting that it could be a path to more personalized health care.
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“It can also be applied to pandemic management by monitoring respiratory infections on a wide scale,” he added.
The ultimate goal is for the EBCare technology to go beyond respiratory diseases, Gao noted.
“As research progresses, we envision that the smart mask can be adapted to detect a wider range of biomarkers, including those related to metabolic, cardiovascular and infectious diseases,” he said.
This schematic shows the process by which the smart mask can detect chemicals in the breath, such as nitrite, which is an indicator of airway inflammation. (Caltech/Wei Gao and Wenzheng Heng)
A study of the mask’s capabilities included 31 healthy adults who wore the EBCare in real-life settings over a 14-hour span, according to Caltech. They only removed the mask for three-minute intervals to eat.
Ten of the participants were smokers, 10 had asthma, nine had COPD and 12 had recently recovered from COVID-19.
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The masks accurately detected the biomarker for asthma and COPD in participating patients. They also successfully detected signs of kidney disease.
EBCare also produced accurate readings of blood alcohol levels.
“Monitoring alcohol levels in real time offers a non-invasive and continuous alternative to breathalyzers or blood tests,” Gao said.
“We would need to see at least a few clinical studies demonstrating that the masks can diagnose better — or more rapidly or with more sensitivity — than the standard of care.”
The research — which was funded by the National Institutes of Health, the National Science Foundation, the Tobacco Related Disease Research Program, and the U.S. Army Medical Research Acquisition Activity — was published in the journal Science on Aug. 29.
The idea is not for the smart mask to replace traditional medical diagnosis, but to provide “early warning” through continuous health monitoring during daily activities and to “bridge the gap” between doctor’s visits, Gao said.
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“The goal is to identify subtle physiological changes before they develop into more severe conditions, giving individuals the opportunity to take proactive steps in managing their health,” he said.
This is especially important for those who need regular monitoring, such as patients with chronic conditions or those recovering from respiratory infections like COVID-19, according to Gao.
The mask (not pictured) is designed to screen for medical conditions like respiratory infections, COPD (chronic obstructive pulmonary disease), asthma and post-COVID infections. (iStock)
“I recommend that health care providers consider integrating real-time EBC analysis technology into their diagnostic and monitoring practices, especially for chronic conditions like asthma and COPD,” he said.
“For individuals, the ability to monitor one’s health non-invasively through a wearable device offers the opportunity to be more proactive in managing personal health, which can lead to early intervention and better health outcomes.”
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MarkAlain Déry, DO, MPH, infectious disease doctor and chief innovation officer at Access Health Louisiana, who was not involved with the development of the smart mask, agreed that it is an “exciting concept.”
“Could it work? Sure,” he told Fox News Digital.
Wei Gao, professor of medical engineering at the California Institute of Technology in Pasadena, led the team that created the EBCare mask. (Caltech)
“However, we would need to see at least a few clinical studies demonstrating that the masks can diagnose better — or more rapidly or with more sensitivity — than the standard of care,” he went on.
“Then, we would need studies that demonstrate clinical improvement.”
Potential limitations
Some external doctors not involved in the mask’s development questioned whether this mode of data collection is beneficial.
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“While the mask introduces an innovative method to monitor exhaled breath condensate (EBC), we need to ask an important question: Do these continuous, real-time measurements genuinely make a difference in everyday life?” said Dr. Brett Osborn, a Florida neurosurgeon, in a conversation with Fox News Digital.
“For the average person, the biomarkers it detects — ammonium, pH, nitrite and alcohol — do not need constant monitoring, especially when routine blood tests can provide this information more accurately and with greater relevance.”
“For the average person, the biomarkers it detects … do not need constant monitoring, especially when routine blood tests can provide this information more accurately and with greater relevance,” a doctor said. (iStock)
Osborn believes that the concept of the EBCare mask is better suited for “specific, high-stakes environments,” such as real-time monitoring of toxic gases in military or industrial settings.
“However, for the average person, especially in a post-pandemic world, the idea of wearing a mask like this is counterproductive,” he said.
Dr. John W. Ayers, PhD, vice chief of innovation in the Division of Infectious Diseases and Global Public Health at the University of California San Diego, also questioned the idea of having patients with asthma or COPD — who already experience breathing difficulties — wear the masks.
“For the average person, especially in a post-pandemic world, the idea of wearing a mask like this is counterproductive.”
The lead researcher, Gao, responded to some of these comments.
“While routine blood tests are indeed reliable, they are typically periodic and require a clinical setting, which limits their ability to capture dynamic, day-to-day physiological changes,” he told Fox News Digital.
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“The real innovation of the EBCare mask lies in its ability to continuously monitor health in real time, offering insights that might not be detectable with intermittent tests.”
For individuals managing chronic conditions like asthma, COPD or metabolic disorders, fluctuations in certain biomarkers can provide early warning signs, according to the researchers. (iStock)
For individuals managing chronic conditions like asthma, COPD or metabolic disorders, fluctuations in certain biomarkers can provide early warning signs before symptoms worsen, allowing for timely intervention, according to the researcher.
Gao, however, did acknowledge some limitations with the EBCare device.
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“One limitation was the relatively small sample size in some of the clinical trials, particularly for conditions like COPD and asthma,” he told Fox News Digital.
“Future studies with larger and more diverse populations will help to further validate the device’s performance across a broader range of conditions and environments.”
Health
‘Weight Loss Has Never Been About Calories’: How This Low-Insulin Diet Helped Lillie, 58, Drop 70 Lbs!
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Big moves are continuing in the weight loss landscape in the new year following breakthrough research of GLP-1 medications and other methods.
Weight-loss experts spoke with Fox News Digital about their predictions for the most major changes to come in 2026.
No. 1: Shift to whole-body treatment
Dr. Peter Balazs, a hormone and weight loss specialist in New York and New Jersey, shared that the most important shift is likely to label GLP-1 drugs as “multi-system metabolic modulators” rather than “simple weight loss drugs.”
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“The treatment goal is no longer just BMI reduction, but total cardiometabolic risk mitigation, with effects now documented across the liver, heart, kidneys and vasculature,” he said.
“We are seeing a significant reduction in major adverse cardiovascular events … and progression of renal disease,” he went on.
The focus of GLP-1 drugs will widen beyond weight loss and diabetes, according to experts’ predictions. (iStock)
Philip Rabito, M.D., a specialist in endocrinology, weight loss and wellness in New York City, also shared that “exciting” advancements lie ahead for weight-loss drugs, including GLP-1s and GIPs.
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“These next‑generation agents, along with novel combinations that include glucagon and amylin agonists, are demonstrating even more impressive weight‑loss outcomes than currently available therapies, with the potential for better tolerability and sustained results,” he told Fox News Digital.
“There is also tremendous optimism around new federal agreements with manufacturers that aim to make these medications more widely accessible and affordable for the broad population of patients who need them most.”
No. 2: More convenient dosing
The typical prescription for a GLP-1 medication is a weekly injection, but delivery and dosing may be changing to more convenient methods in 2026, according to Balazs.
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A daily 25 mg pill version of Novo Nordisk’s Wegovy, a semaglutide designed to treat obesity, is now approved and available for chronic weight management, offering a non-injectable option for some patients.
A once-weekly oral GLP-1 is currently in phase 2 trials, as well as an implant that aims for three to six months of drug delivery, Balazs noted.
Incisionless weight-loss procedures will rise as a lower-risk option, according to experts. (iStock)
No. 3: Less invasive surgery
In addition to decreased risk during surgery for GLP-1 users, Balazs also predicted that metabolic surgery without incision will rise as a better option.
“Incisionless endoscopic procedures — like endoscopic sleeve gastroplasty (non-surgical weight-loss procedure that makes the stomach smaller from the inside) and duodenal mucosal resurfacing (non-surgical procedure that resets part of the small intestine to help the body better handle blood sugar) — [may become] more durable and widely available,” he said.
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“These offer significant metabolic benefits with shorter recovery and lower risk than traditional surgery.”
Rabito agreed that “rapid progress” in minimally invasive weight‑loss procedures is “opening powerful new options for patients who are hesitant to pursue traditional bariatric surgery.”
Bariatric surgery remains the most effective weight loss method, one specialist says. (iStock)
This avenue offers “meaningful and durable weight reduction with less risk, shorter recovery times and no external incisions,” the expert added.
Dr. Muhammad Ghanem, bariatric surgeon at the Orlando Health Weight Loss & Bariatric Surgery Institute, reiterated that surgery remains “the most successful modality for the treatment of obesity … with the highest weight loss and most durable outcomes as of yet.”
No. 4: Younger GLP-1 users
As Novo Nordisk’s Wegovy has been indicated for adolescents over 12 years old as an obesity treatment, Balazs commented that pediatric use of weight-loss drugs is “now a clinical reality.”
He predicted that other alternatives are likely to be approved in 2026 for younger users.
No. 5: High-tech, personalized access
Amid the growth of artificial intelligence, Balazs predicted an expansion in the clinical implementation of AI-driven weight-loss methods.
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This could include categorizing obesity into sub-types like “hungry brain,” “emotional hunger” and “slow burn” to personalize how therapy is prescribed while moving away from “trial and error,” he said.
Ghanem agreed that there will likely be a “big focus” on individualized testing for causes of obesity in 2026, as it’s a disease that can have “different causes in different people,” thus requiring different treatments.
AI and other digital opportunities will drive more access for weight-loss patients, experts say. (iStock)
The doctor anticipates that more patients will seek combinations of comprehensive treatments and programs.
“Patients are more aware that now we have a few weapons in our arsenal to combat obesity, and [they] are seeking a multidisciplinary and holistic approach,” Ghanem said.
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Treatment options will also turn digital with the rise of prescription digital therapeutics (PDTs) for weight loss, Balazs predicted.
“These are software applications delivering cognitive behavioral therapy, personalized nutrition and metabolic coaching through algorithms, often integrated with continuous glucose monitors, and reimbursed as medical treatments,” he said.
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Ghanem added that body composition analyzers, like DEXA scans, will likely be more widely used as awareness grows about the limitations of BMI and weight in assessing obesity.
Congratulations, you’ve reached the final day of the Brain Health Challenge! Today, we’re asking you to do a few things that might feel a bit out of left field — like getting your blood pressure checked.
No, it isn’t as fun as playing Pips, but experts say it’s one of the most important things you can do for your brain. That’s because heart health and brain health are intrinsically linked.
High blood pressure, in particular, can damage brain cells, and it’s a significant risk factor for stroke and dementia. When blood pressure is too high, it places stress on the walls of arteries in the brain. Over time, that added stress can cause the blood vessel walls to thicken, obstructing blood flow. In other cases, the increased pressure causes the artery walls to thin and leak blood into the brain.
These changes to the blood vessels can sometimes cause a large stroke to occur. More commonly, the damage leads to micro-strokes and micro-hemorrhages, which cause fewer immediate problems and often go unnoticed. But if someone has hypertension for years or decades, these injuries can build up, and the person may start to experience cognitive impairment.
High blood pressure “is known as a silent killer for lots of reasons,” said Dr. Shyam Prabhakaran, the chair of neurology at the University of Chicago. “It doesn’t cause you any symptoms until it does.”
Because the damage accumulates over many years, experts say that managing blood pressure in midlife matters most for brain health. Hypertension can be addressed with medication or lifestyle changes, as directed by your doctor. But the first thing you need to do is know your numbers. If your blood pressure comes back higher than 120/80, it’s important to take it seriously, Dr. Prabhakaran said.
While you’re at it, there are a few other aspects of your physical health that you should check on.
Your eyes and ears are two of them. Hearing and vision loss have both been shown to increase the risk of dementia. Experts think that with less sensory information coming in to stimulate the brain, the regions that process hearing and vision can start to atrophy. What’s more, people with sensory loss often withdraw or are left out of social interactions, further depriving them of cognitive stimulation.
Oral health can also affect your brain health. Research has found a connection between regular flossing and reduced odds of having a stroke. That may be because good oral health can help to reduce inflammation in the body. The bacteria that cause gum disease have also been tied to an increased risk of Alzheimer’s.
And have you gotten your shingles vaccine? There is mounting evidence that it’s a powerful weapon for protecting against dementia. One study found that it lowered people’s odds of developing the condition by as much as 20 percent.
To wrap up this challenge, we want you to schedule a few medical appointments that benefit your brain, as well as your body.
After five days of feeding, exercising and challenging your brain, you are well on your way to better cognitive health. Thanks for joining me this week, and keep up the good habits!
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