Health
RFK Jr. Rattles Food Companies With Vow to Rid Food of Artificial Dyes
In his first meeting with top executives from PepsiCo, W.K. Kellogg, General Mills and other large companies, Robert F. Kennedy Jr., the health secretary, bluntly told them that a top priority would be eliminating artificial dyes from the nation’s food supply.
At the Monday meeting, Mr. Kennedy emphasized that it was a “strong desire and urgent priority” of the new Trump administration to rid the food system of artificial colorings.
In addition, he warned the companies that they should anticipate significant change as a result of his quest for “getting the worst ingredients out” of food, according to a letter from the Consumer Brands Association, a trade group. The Times reviewed a copy that was sent to the group’s members after the meeting.
And while Mr. Kennedy said in the meeting that he wanted to work with the industry, he also “made clear his intention to take action unless the industry is willing to be proactive with solutions,” the association wrote.
“But to underscore, decision time is imminent,” Melissa Hockstad, who attended the meeting and is the group’s president, wrote in the letter.
Later on Monday, Mr. Kennedy issued a directive that would also affect food companies nationwide. He ordered the Food and Drug Administration to revise a longstanding policy that allowed companies — independent of any regulatory review — to decide that a new ingredient in the food supply was safe. Put in place decades ago, the policy was aimed at ingredients like vinegar or salt that are widely considered to be well-understood, and benign. But the designation, known as GRAS, or “generally recognized as safe,” has since grown to include a far broader array of natural and synthetic additives.
Mr. Kennedy had vowed to upend the food system as a way to address growing rates of chronic disease and other health concerns even before his appointment as the head of the Department of Health and Human Services. He now oversees the F.D.A., the federal regulator for about 80 percent of the nation’s food supply.
Many food companies rely on artificial dyes to make breakfast cereals and candies dazzling shades of pink and blue, for instance, or beverages neon orange. Some have already tried to adapt natural ingredients, like carrot or blueberry juice, for coloring, particularly for products sold in international markets, like Canada. But the companies have said that consumer demand had weakened in the United States because of dissatisfaction with less appealing or vivid colors in snacks and drinks.
Steven Williams, the chief executive of PepsiCo’s North America division, attended the meeting with Mr. Kennedy, but the company said he would not comment. In an email, a PepsiCo spokesperson said that the company viewed the meeting as a “productive first step” and added that it was focused on providing consumers “more options with natural ingredients, no synthetic colors and reductions in sugar, fat and sodium.”
Stacy Flathau, the chief corporate affairs officer for W.K. Kellogg, said in an emailed statement that the company looked forward to working with the new administration.
While the industry memo expressed alarm about the plan to remove synthetic colors, it did not address Mr. Kennedy’s additional proposal targeting some food ingredients deemed safe.
Advocates for food safety have criticized the existing GRAS policy as a loophole that enables food companies to introduce untested ingredients that in some cases have proven hazardous. About 1,000 ingredients deemed safe have been reviewed by the F.D.A., but Mr. Kennedy targeted the ones that companies deem acceptable with no government oversight.
“Eliminating this loophole will provide transparency to consumers, help get our nation’s food supply back on track by ensuring that ingredients being introduced into foods are safe, and ultimately Make America Healthy Again,” Mr. Kennedy said in a statement.
Bills to remove synthetic colors from the food supply have taken off since California banned Red Dye No. 3, a move that the F.D.A. followed. Other state proposals have targeted titanium dioxide, a compound used to make food appear shiny. Texas and West Virginia have moved to strip colorants from some school lunches.
In Ms. Hockstad’s letter to food company executives, she said Mr. Kennedy wanted synthetic color additives known as FD&C colors, or Food, Drug & Cosmetic dyes, removed during his administration.
Vani Hari, an activist known online as the Food Babe who did not attend the meeting, applauded Mr. Kennedy’s willingness to take on the food industry. “Bobby gave the food industry an ultimatum,” she said. “Either work with us to make these changes happen or we’ll do it ourselves.”
Mr. Kennedy was expected to meet with members of the Make America Healthy Again commission on Tuesday.
Stuart Pape, a lawyer who represents food companies, said Mr. Kennedy’s plan was “ambitious.” He said the F.D.A. traditionally had proposed removal of one coloring at a time, presenting research on why the ingredient was unsafe. Whether there is an adequate supply of alternative colorings would be a concern of a broader plan.
“I think Kennedy has made no secret that he intends to go after the food ingredients,” Mr. Pape said. “And I think this is the opening of that war.”
Dr. Peter Lurie, a former F.D.A. official and director of the Center for Science in the Public Interest, an advocacy group, said the effort might not have a significant effect on major chronic diseases including diabetes and heart disease.
The data on cancer related to food dyes was mostly focused on Red No. 3, he said. In the waning days of the Biden administration, the F.D.A. issued a ban on Red No. 3 that would take effect in the coming years. Red dye No. 3 has been linked to some cancers in animals, but not in humans.
Still, he said that Mr. Kennedy’s move might be effective because the dyes do little other than to make unhealthy food appear more appealing. Despite spending years fighting efforts to limit food dyes, he said, food executives may join other business leaders who have been eager to kowtow to the current administration.
“Given their fear of angering the administration,” Dr. Lurie said, “they may just see it in their interest to go along with this.”
Health
Murdoch Children’s Research Institute secures $5M grant to prevent childhood disease
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The Murdoch Children’s Research Institute (MCRI) in Australia will receive a $5 million federal grant to launch a pioneering research team for children’s health.
The grant was announced at MCRI’s 40th anniversary gala in Melbourne on Saturday night.
“For 40 years, MCRI has been a global leader in children’s health research,” Prime Minister Anthony Albanese told guests at the gala, which was attended by 300 of Australia’s most esteemed medical experts, political leaders, philanthropists and sports luminaries.
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“My government is proud to partner with MCRI, so our world-leading researchers have the best opportunities to support healthier childhoods for Australians now and into the future.”
The $5 million will directly support medical research aimed at preventing numerous childhood conditions, including obesity, heart disease, mental health issues and disabilities.
Australian Prime Minister Anthony Albanese speaks at the MCRI gala. (Penny Stephens/Murdoch Children’s Research Institute)
Also announced at the gala, a lead donation from Sarah and Lachlan Murdoch will launch the Horizon Fund — a permanent endowment for MCRI aimed at funding long-term children’s health research and future medical breakthroughs.
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The goal is for the fund to raise between $50 million and $100 million in its first year and to reach $200 million within five years.
The fund is designed to back researchers’ immediate priorities while safeguarding long-term capital for future medical breakthroughs in children’s health.
Pictured above, Sarah Murdoch (MCRI co-chair); Jodie Haydon (wife of Prime Minister Albanese); Australian Prime Minister Anthony Albanese; Kathryn North (MCRI director); and Patrick Houlihan (MCRI chair). (Christopher Hopkins/Murdoch Children’s Research Institute)
In 2020, the Murdochs donated $5 million to establish a perpetual fellowship supporting leading researchers in fields including stem cell technology and genomic precision medicine.
Co-founded in 1986 by philanthropist and child health advocate Dame Elisabeth Murdoch and pediatrician and genetics pioneer Professor David Danks, MCRI comprises 1,800 scientists, researchers and clinicians.
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“Dame Elisabeth’s leadership, along with her values, shaped both the direction and the ethos of the Institute we were to become – for all children to live a healthy and fulfilled life,” said Sarah Murdoch, who is Dame Elisabeth Murdoch’s granddaughter-in-law and MCRI’s global ambassador and board co-chair.
Sarah Murdoch (MCRI co-chair) is pictured with Kathryn North (MCRI director) at the Murdoch Children’s Research Institute 40th Anniversary Gala at the State Library Melbourne. (Penny Stephens/Murdoch Children’s Research Institute)
“With the generosity of a remarkable group of founding donors alongside the Murdoch family – Sir Jack Brockhoff, the Miller family, and The Scobie and Claire Mackinnon Trust – the foundations were laid for an Institute designed to bring our brightest minds, to serve all children, not only in that moment, but for generations to come,” Ms. Murdoch added.
“I see what is possible when foresight, science, commitment, collaboration and heartfelt generosity come together,” she emphasized.
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“Because behind every breakthrough is a child — a family desperate for answers. A future changed because of the commitment by so many.”
MCRI Director Kathryn North expressed appreciation at the gala to the prime minister for the $5 million grant.
“From the beginning, MCRI has been guided by a simple but powerful purpose: to give all children the opportunity to live a healthy and fulfilled life,” said the MCRI director. (MCRI)
“From the beginning, MCRI has been guided by a simple but powerful purpose: to give all children the opportunity to live a healthy and fulfilled life,” North said.
“It reflects a belief that good health is the foundation for a full life, and that opportunity should never be limited by circumstance.”
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Professor North mentioned the Institute’s focus on developing therapies for previously incurable diseases.
“We are harnessing the power of human stem cell technologies to grow heart patches, functional mini kidneys, blood and immune cells … to better understand disease, and to develop regenerative therapies using a patient’s own stem cells to replace organ transplants and the risk of rejection,” she said.
The Institute’s next challenge is to address chronic conditions like asthma, obesity, allergies and mental health conditions that can persist for decades. (iStock)
The Institute’s next challenge, North said, is to address chronic conditions like asthma, obesity, allergies and mental health conditions that can persist for decades.
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“These are big problems that will require significant and ongoing support,” she said. “Through our work globally, we are helping communities raise their expectations to both deliver and receive the sort of healthcare we take for granted.”
“Our ambition now is to translate these partnerships into population-scale solutions that improve the lives of millions of children worldwide,” North added. “This is not simply the next chapter for MCRI – it is the work of building the future of children’s health.”
Health
New pancreatic cancer pill could reshape treatment as early trial results stun researchers
FDA fast-tracks pancreatic cancer drug daraxonrasib
Family and emergency medicine physician Dr. Janette Nesheiwat discusses how artificial intelligence could help detect pancreatic cancer earlier and the FDA fast-tracking the drug daraxonrasib on ‘Fox Report.’
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A new drug for pancreatic cancer is showing promise in early testing.
Daraxonrasib is a daily pill designed to block cancer signals linked to the RAS gene. It has now finished an early-stage clinical trial — the first time it was tested in people — to evaluate both its safety and effectiveness.
The clinical trial, led by the Dana-Farber Cancer Institute and published in The New England Journal of Medicine, tested the drug in 168 patients with advanced pancreatic cancer whose tumors had mutations in the RAS gene. All study participants had previously received at least one chemotherapy treatment.
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The drug is designed to block multiple active cancer signals that help tumor cells grow. This is especially important because more than 90% of pancreatic cancers carry these harmful mutations, researchers said.
Existing and older drugs that target RAS mutations only work on certain types that are uncommon in pancreatic cancer, such as KRAS mutations.
Daraxonrasib is a daily pill designed to block cancer signals linked to the RAS gene. It has now finished an early-stage clinical trial to evaluate its safety and effectiveness. (iStock)
At the 300-milligram dose — the amount that will be used in larger phase 3 trials — about 30% of patients saw a positive response, researchers noted. Overall, about 90% of patients had their cancer either shrink or stop getting worse.
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There were some side effects reported — most commonly rash, mouth inflammation, nausea and diarrhea.
Lead investigator Dr. Brian Wolpin, director of the Hale Family Center for Pancreatic Cancer Research at Dana-Farber, commented in a press release statement that this development could change the future of cancer care.
About 90% of patients treated with the drug experienced disease control, meaning their cancer was reduced or stabilized. (iStock)
“If supported by data from future clinical trials, daraxonrasib would be a targeted therapy relevant to nearly all patients with advanced pancreatic cancer,” he said.
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“This trial provides the first published data showing the safety and broad activity of a RAS(ON) multi-selective inhibitor in pancreatic cancer,” Wolpin went on. “If it proves effective in larger clinical trials, it would signify a substantial shift in how this disease is treated.”
In an interview with Fox News Digital, the researcher claimed that daraxonrasib represents “one of the most promising therapy advances we’ve seen in pancreatic cancer.”
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This is especially significant since pancreatic cancer has had “very few effective therapies” in the past, Wolpin noted.
“The study also showed disease control in approximately 90% of patients with metastatic pancreatic cancer, which is extremely exciting,” he added.
The study does not prove daraxonrasib is superior to standard treatment of chemotherapy, researchers noted. (iStock)
Wolpin noted that while side effects were common, most patients were able to tolerate treatment with “supportive care measures, and very few patients needed to stop therapy due to side effects.”
As this was a phase 1/2 study, it does not “definitively prove” the superiority of daraxonrasib compared to chemotherapy, Wolpin added.
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“The study did not include a randomized control arm that directly compared daraxonrasib with chemotherapy,” he said. “That being said, the results for daraxonrasib looked substantially better than what we have seen in prior clinical trials of chemotherapy in patients with previously treated metastatic pancreatic cancer.”
It also remains unclear how the drug may perform earlier in the disease, as the trial included patients who had already received prior treatments.
“Additional research is needed to determine how best to sequence or combine therapies to provide the most durable responses and cures,” the lead investigaror sid. (iStock)
For patients and families affected by pancreatic cancer, Wolpin noted that daraxonrasib signals “real momentum” toward effective treatments, but it is still investigational and is not a cure.
“Pancreatic cancer remains a challenging disease, and additional research is needed to determine how best to sequence or combine therapies to provide the most durable responses and cures,” he said.
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Brian Slomovitz, director of gynecologic oncology and co-chair of the Cancer Research Committee at Mount Sinai Medical Center in Miami Beach, applauded this development in a separate interview with Fox News Digital.
“We are anxiously awaiting the upcoming plenary presentation of RASolute 302 at the ASCO meeting later this month,” said the expert, who was not involved in the study. “Greater than 90% of pancreatic cancers have activation of kRAS, which is a major factor in the development and progression of these cancers.”
“Doubling the survival time in pretreated patients is unprecedented.”
“If the full dataset results that will be reported later this month confirm what was earlier released, I believe this will be one of the most important breakthroughs in all solid tumors,” Slomovitz went on. “Doubling the survival time in pretreated patients is unprecedented.”
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The doctor added that the “magnitude of benefit” could “reshape the treatment landscape” and “establish a new standard of care.”
“We will need to evaluate the full dataset for efficacy and safety,” Slomovitz added. “I am more than cautiously optimistic, and I am truly excited for our patients and their families that suffer from this dreadful disease.”
Health
Frequent museum visits tied to reduced cellular aging, research finds
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People who regularly visit museums or participate in creative activities may be aging more slowly on a biological level, according to a new study from the United Kingdom.
Researchers from University College London analyzed data from more than 3,500 adults and found that people who frequently engaged in arts and cultural activities showed signs of slower biological aging in several DNA-based measurements.
The findings were published in the journal Innovation in Aging.
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The study examined activities including painting, photography, dancing, singing, visiting museums and attending cultural events or historic sites.
People who frequently visit museums or engage in artistic activities may experience slower biological aging. (iStock)
Researchers compared participation in those activities with “epigenetic clocks,” scientific tools that examine chemical changes in DNA over time.
Adults who participated more often, and in a wider variety of activities, tended to show slower aging scores compared to people who rarely engaged in arts or cultural experiences.
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The association appeared even stronger among adults over age 40.
Researchers also noted that the effect sizes were comparable to those linked to physical activity, one of the most widely studied behaviors associated with healthy aging.
The study found that adults who engaged more often in arts and cultural activities showed slower biological aging. (iStock)
Jessica Mack, a health and wellness expert and founder of The Functional Consulting Group who was not involved in the study, said the findings reflect a growing understanding that health is influenced by more than exercise and nutrition alone.
“Arts and cultural engagement may be associated with slower epigenetic aging, with effects comparable in some measures to physical activity,” Mack told Fox News Digital.
She said activities such as visiting museums and engaging with music or art may help reduce stress, improve emotional regulation and increase social connection.
Experts say these activities may reduce stress, improve emotional regulation, and strengthen social connections. (iStock)
“These are not ‘extra’ lifestyle activities,” Mack said. “They may be deeply connected to how the body manages inflammation, stress hormones, mood and overall resilience.”
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Mack added that people experiencing stress, social isolation, retirement or caregiving responsibilities may especially benefit from meaningful cultural engagement.
Experts cautioned, however, that the study does not prove arts engagement directly slows aging.
“This is an observational study, not an experiment,” Professor Steve Horvath of UCLA, a longevity researcher and pioneer in epigenetic aging research who was not involved in the study, told Fox News Digital.
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“So when researchers find that the people who go to museums have younger epigenetic age, we cannot tell whether the museum visits slowed their aging, or whether their slower aging is what allowed them to keep visiting museums,” he said.
While the findings suggest a link, experts caution that the study cannot prove arts and cultural activities directly slow aging. (iStock)
Horvath said both explanations may be true to some degree, though he described the research as “methodologically careful” and worthy of further study.
The findings remained consistent even after accounting for factors such as smoking, income, body weight and other lifestyle habits.
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He added that regardless of whether arts engagement is directly slowing biological aging, staying socially and mentally active is still associated with healthier aging overall.
“The prescription is the same,” he said. “Keep going.”
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