Health
Rare spinal cancer tumor removed through patient’s eye at university hospital
A young Maryland woman is “relieved and recovering” after doctors performed a novel surgery to remove her potentially deadly cancerous tumors.
A surgical team at the University of Maryland Medical Center (UMMC) extracted the tumors, which had wrapped around the spinal cord, through the patient’s eye socket.
This was the first time surgeons removed a spinal tumor using a “transorbital” approach, according to a UMMC press release.
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Karla Flores was just 19 when she was diagnosed with a chordoma, which is a developmental bone tumor, in her spine.
At 18, Flores started experiencing double vision, ultimately leading to her diagnosis months later.
Karla Flores, taken in March 2025. Her face is absolutely scarless after all her surgeries. (Karla Flores)
Chordomas are very rare, with only about 300 cases occurring in the U.S. each year.
“The tumor was wrapped around the patient’s spine and spinal cord and had invaded the vertebrae in her neck, just below the base of the skull,” according to Mohamed Labib, M.D., neurosurgeon at the University of Maryland Medical Center and assistant professor of neurosurgery at the University of Maryland School of Medicine.
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“The primary risks were injuring the brainstem, spinal cord or major blood vessels with the drill or the fine instruments we used — any of these injuries could have resulted in paralysis or even death,” Labib told Fox News Digital.
“But without surgery, the chordoma could have continued to grow and put intense pressure on the spinal cord. This, too, would have paralyzed her arms and legs and eventually killed her. So, you can see how the stakes were very high with this procedure.”
From left to right, Dr. Kalpesh Vakharia, Dr. Mohamed Labib and Dr. Andrea Hebert of the University of Maryland Medical Center. (University of Maryland Medical Center)
The surgeons created a “huge surgical corridor” through the eye socket that enabled them to get in front of the spinal cord.
“It was a straight shot,” Labib said.
“By going through the bottom of the eye socket, we were able to remove a tumor that otherwise would have been very difficult and very risky to address.”
“Learning about the spinal and brain tumors was terrifying, but I am so grateful the doctors were able to remove them.”
During the procedure, Labib worked with a facial plastic and reconstructive surgeon, Kalpesh T. Vakharia, M.D., who “carefully cut through the conjunctiva, the transparent membrane protecting the eye, inside the lower eyelid without disturbing the eye.”
To create the pathway to the spine, Vakharia removed the bottom of Flores’ eye socket and a portion of her cheekbone, the release stated.
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“We wanted to develop a surgical plan where there would be no external scars and it would be impossible to tell that the patient even had surgery,” said Vakharia.
After Labib removed the tumor, Vakharia rebuilt the bottom of the eye socket using a titanium plate and rebuilt the cheek with bone from the patient’s hip, the release detailed.
This is an illustration of the patient’s two spinal tumors. (University of Maryland Medical Center)
“It was amazing to have had the opportunity to be part of surgery that had never been done before,” Vakharia added.
This approach also prevented any damage to the eustachian tube, major blood vessels such as the jugular vein and internal carotid artery, and nerves that control swallowing and speech, Labib noted.
Prior to Flores’ surgery, Labib had the chance to practice the transorbital procedure on cadavers “many, many times.”
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“The fact that people are willing to donate their bodies to science enabled us to do this and saved the life of this young woman,” he said.
Flores also had a large tumor around her brain stem, which was removed through two separate procedures via her skull and nose, the release stated.
An illustration of the transorbital path to the patient’s tumors. (Tina Wang/University of Maryland Medical Center)
The spinal tumors could have been life-threatening if they had grown to the point where they caused significant brain stem compression, according to Andrea M. Hebert, MD, a UMCC head and neck surgeon who performed the endonasal procedure and took part in the transorbital surgery.
“Many of these tumors recur, and that’s why we favor a multidisciplinary approach to treatment,” said Hebert in the release.
Flores has also undergone radiation therapy to eliminate any remaining cancer cells.
“Karla is doing really well — she’s recovered from surgery and radiation and is ready to get back to work and school,” Labib shared with Fox News Digital.
“She’s an incredibly brave young woman who has faced more than most her age. I expect that same strength of spirit will carry her into a promising future.”
“Learning about the spinal and brain tumors was terrifying, but I am so grateful the doctors were able to remove them.”
Flores does have some nerve damage due to the tumor’s proximity to the brain stem, which has caused some issues with movement of her left eye.
“Learning about the spinal and brain tumors was terrifying, but I am so grateful the doctors were able to remove them,” said Flores, who plans to go to school to become a manicurist.
Karla Flores is pictured on the left, plus the team of doctors that handled the procedure. (Karla Flores; University of Maryland Medical Center)
“I’m slowly recovering and with any problem I have, they help me,” she continued.
“I keep reminding myself to take one day at a time and know that each step is an accomplishment.”
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Flores now plans to go to school to become a manicurist.
Looking ahead, UMMC’s team plans to demonstrate the transorbital procedure this fall to neurosurgeons from around the world, at their annual Skull Base surgery course.
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“When you have such a broadened corridor to reach these tumors, you can completely remove them, which greatly reduces recurrence of the cancer,” Labib told Fox News Digital.
“We also have other patients who will be receiving similar surgeries in the near future.”
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Journalist Katie Couric is sharing a scary medical episode that she experienced on June 27.
In a post on Substack titled “The Day I’ll Never Remember,” she detailed a sudden episode that left her unable to recall the current month, year and president.
“I thought it was 2024. And I believed Joe Biden was president,” she wrote.
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The event occurred while Couric was attending the Aspen Ideas Festival in Colorado, during which she participated in two public panels — one on AI and one on journalism — both of which she cannot remember at all.
“I have no idea what we talked about, or of what occurred when the panels ended,” she said.
Journalist Katie Couric is sharing a scary medical episode that she experienced on June 27. (Getty Images)
John Molner — Couric’s husband, who was in attendance at the festival and the two panels — also shared his account.
After the event, someone told Molner that Katie wasn’t feeling well. When he reached her, an EMT and a doctor were tending to her. “I could tell something was off,” he wrote. “It could have been altitude sickness, but Katie was definitely not all there.”
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At the hospital, when Couric struggled to recall the year, the president and her grandchildren’s names, doctors began checking for a stroke.
An MRI revealed no signs of stroke, which was a relief, but “Katie’s ‘fog’ became a lot more apparent,” Molner wrote.
John Molner, Couric’s husband, who was in attendance at the festival and the two panels, also shared his account. (Getty Images)
“She repeatedly asked me the same questions: ‘What was I doing before we got to the hospital?’ ‘Why am I at the hospital?’”
Couric was ultimately diagnosed with transient global amnesia, a sudden, temporary episode of memory loss that prevents a person from forming new memories and may also erase some recent memories, according to Mayo Clinic.
“The cause seems to be as mysterious as the brain itself.”
It is not caused by a stroke, seizure or head injury, and it usually resolves completely within 24 hours.
“[It’s] just a very weird neural episode that’s pretty uncommon and, at least in most cases, is a ‘one and done’ experience,” Molner said.
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Couric said she finally began feeling “like herself” again around 9 p.m. and went to sleep at 2 a.m.
As TGA leaves a “permanent gap in memory” for the duration of the episode and for hours beforehand, Couric said that from around noon on that day until at least 7 p.m. will remain a “big, black hole.”
As TGA leaves a “permanent gap in memory” for the duration of the episode and for hours beforehand, Couric said that from around noon on that day until at least 7 p.m. will remain a “big, black hole.” (Getty Images)
Data shows that approximately three to eight people per 100,000 will have an episode of transient global amnesia, with people 50 years of age and older at higher risk.
The specific cause of TGA is not known, but some experts believe it stems from a “temporary dysfunction in the brain’s hippocampus — the area responsible for creating new memories,” Couric shared.
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“Doctors believe this is driven by brief interruptions in blood or oxygen flow, or microscopic spasm in the blood vessels.”
Episodes could potentially be triggered by intense physical exertion, emotional distress, extreme temperature changes or migraines, experts say.
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Approximately 15% of patients will have a recurrence 10 years later.
“Why did this happen to me? Was the altitude an issue? Was I dehydrated? Tired? Stressed? The literature doesn’t seem to indicate that these are contributing factors, but the cause seems to be as mysterious as the brain itself,” Couric wrote.
Anyone who experiences sudden memory loss, confusion, difficulty speaking, weakness, numbness, vision changes, severe headache or other stroke-like symptoms should seek immediate medical attention or call 911, doctors advise. (iStock)
“All I know is that those hours will be forever lost. Someone described it as my brain failing to hit the ‘record button.’”
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“While this was a freaky occurrence, it could have been much more serious. So ultimately, I’m relieved — even though several hours of a Saturday in June will always be missing for me.”
Anyone who experiences sudden memory loss, confusion, difficulty speaking, weakness, numbness, vision changes, severe headache or other stroke-like symptoms should seek immediate medical attention or call 911, doctors advise.
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Older adults identified as “super movers” are about half as likely to develop cognitive impairment than their peers.
That’s according to a recent study led by Stony Brook Medicine in New York, which evaluated the cognitive function of 4,000 adults 80 and over who participated in multiple aging and longevity studies over several years.
Among this group, 6% to 10% were classified as super movers, which means they walk at a much faster pace than others of the same age and gender — at speeds comparable to people three decades younger.
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The super movers were found to have about half the risk of cognitive decline compared to seniors with typical gait speed.
The findings were published in the journal Neurology on June 16.
Older adults identified as “super movers” are about half as likely to develop cognitive impairment than their peers. (iStock)
“The study reinforces that mobility and brain health are closely connected,” lead study author Dr. Joe Verghese, MD, neurologist at Stony Brook Medicine, told Fox News Digital. “This suggests that preserving mobility may be an important marker of healthy brain aging and resilience.”
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The most intriguing finding, according to Verghese, was that super movers maintained cognitive function despite having similar dementia-related brain changes as their peers.
In postmortem brain analysis, there was no difference in dementia-related pathologies between the super movers and the slower walkers, the study stated.
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“This suggests they may possess resilience mechanisms that help preserve brain function even in the presence of age-related changes,” he said. “Understanding these resilience factors could lead to new strategies for promoting healthy brain aging.”
As the study was observational, there were some limitations, and it does not prove that walking faster prevents dementia, the researchers noted.
Super movers were found to have about half the risk of cognitive decline compared to seniors with typical gait speed. (iStock)
“Other factors, such as cardiovascular health, physical fitness or genetics, may also contribute to both faster walking and better cognitive outcomes,” Verghese said.
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This study adds to growing evidence that what’s good for the heart and muscles also benefits the brain, he noted, adding that “staying physically active remains one of the most effective, evidence-based ways to support healthy aging.”
“Walking speed is best viewed as a marker of overall health, not a treatment.”
“The broader message is that physical activity is important at any age,” Verghese said. “Walking is an easy step-up point because you don’t need any special equipment. You can do it inside or outdoors, and you can do it on a regular basis. You can walk with a dog, you can walk with a friend.”
Any activity is beneficial if it’s done regularly and with the right intensity, he added.
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Rather than just trying to walk faster, the neurologist recommends that seniors focus on maintaining mobility through regular physical activity, strength training, balance exercises and good cardiovascular health.
“Walking speed is best viewed as a marker of overall health, not a treatment,” Verghese noted.
Major public health guidelines from the CDC and U.S. Physical Activity Guidelines recommend at least 150 minutes of moderate-intensity aerobic activity each week, such as brisk walking.
Major public health guidelines from the CDC and U.S. Physical Activity Guidelines recommend at least 150 minutes of moderate-intensity aerobic activity each week, such as brisk walking. (iStock)
This can be achieved by walking 30 minutes a day, five days a week, or about 20 to 25 minutes most days. Another option is to engage in shorter sessions that add up over the day.
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“You have to do it within your health limitations and medical conditions,” Verghese advised. “So if there are any medical concerns, I would get your physician to clear you before starting exercise.” The good thing about walking, he added, is that you can start at a slow pace and then gradually build up to a brisker pace.
“And then adding on strength and balance training, whatever age you are, I think is also important.”
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