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Long COVID could be the cause of your bad hangovers, study finds: 'Bad reaction'

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Long COVID could be the cause of your bad hangovers, study finds: 'Bad reaction'

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Drinking too much is often a recipe for a morning-after disaster.

But for long COVID patients, hangover symptoms might be much worse, according to research.

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A small study by Stanford University, which was published in the journal Cureus, examined alcohol sensitivity in four people with post-acute sequelae of SARS-CoV-2 (PASC), or long COVID.

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Two patients reported worse headaches after drinking the same amount of alcohol they would have consumed prior to having COVID.

One patient, a 40-year-old woman with a history of Ehlers-Danlos syndrome type III, asthma, anemia, hypotension and migraines, claimed that she could tolerate seven mixed drinks containing hard liquor in one night before long COVID struck.

For long COVID patients, hangover symptoms might be much worse, according to new research from Stanford University. (iStock)

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But ever since getting COVID, the woman reported that her hangovers feel like she “suffers from alcohol poisoning after drinking even small amounts of alcohol and feels ‘terrible’ for several days after consumption,” the study reported.

The woman noted that her tolerance had decreased so significantly that one beer would result in a “severe hangover, along with exacerbation of PASC symptoms for three days thereafter.” 

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Another patient, a 49-year-old woman with a history of type 1 diabetes, celiac disease controlled by diet, and breast cancer — who consumes several drinks per week — said she noticed a decreased alcohol tolerance after her COVID infection.

After drinking just one glass of wine, she reported experiencing “such a bad reaction that she felt she could not move,” the researchers noted.

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Some patients reported having worse headaches after drinking the same amount of alcohol they would have consumed prior to having COVID. (iStock)

The woman described her symptoms as “similar to a bad hangover, with a headache, grogginess and ‘overwhelming’ fatigue the next day.”

The research concluded that new-onset alcohol reactions and sensitivity can occur after COVID-19 infection in patients with PASC. 

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“Clinicians assessing PASC patients should inquire about alcohol consumption and tolerance in their social history, as this information can provide insights into potential triggers for worsening symptoms and help guide lifestyle management strategies,” the study suggested.

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Stanford Internal Medicine director and study co-author Linda Geng noted how “the clinical observations from this paper raise important questions about the link between long COVID and alcohol sensitivity,” as provided in a statement sent to Fox News Digital.

The research concluded that new-onset alcohol reactions and sensitivity can occur after COVID-19 infection in patients with PASC. (iStock)

“Studying this further might provide insights about the mechanism(s) of long COVID and other post-viral syndromes,” she said. 

“Additionally, patients with long COVID should be cautious about the use of alcohol, and some may feel better if they avoid it altogether.”

“Alcohol can worsen the post-COVID symptoms.”

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Fox News medical contributor Dr. Marc Siegel, who was not involved in the study, noted that although this research surveyed only four patients, he also has recognized an increased sensitivity to alcohol in some of his own PASC patients.

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“[This study] builds on previous research that in the case of post-viral syndromes (including mononucleosis), sensitivity to alcohol can increase,” Siegel said via email to Fox News Digital.

“I have seen this in some of my patients with post-COVID syndromes,” he went on. “The symptoms are similar: headache, nausea, fatigue, body aches. And alcohol can worsen the post-COVID symptoms.”

Siegel explained that both post-COVID symptoms and alcohol can “lead to inflammation and affect the immune system.”

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“And recent research shows that COVID can lead to some leakiness in the blood brain barrier so that inflammatory chemicals (including those from alcohol) can get into the brain at least temporarily, causing headache, nausea and dizziness,” he said.

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Bala Munipalli, M.D., an internist at Mayo Clinic in Florida, also weighed in on this study, noting to Fox News Digital that post-viral persistence of symptoms is “not unique to COVID-19.”

Munipalli was also not involved in the study.

“We have seen this occurring since the 1918 Spanish flu, and saw it with SARS-CoV-1 in 2003 and with Middle Eastern Respiratory Syndrome (MERS) in 2012,” she said. 

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“Recent research shows that COVID can lead to some leakiness in the blood brain barrier so that inflammatory chemicals (including those from alcohol) can get into the brain at least temporarily, causing headache, nausea and dizziness,” a doctor said. (iStock)

“Individuals with PASC have shared symptoms with ME/CFS, fibromyalgia, mast cell activation syndrome, and dysautonomia: fatigue, brain fog, un-refreshing sleep, myalgias, and food and medication sensitivities,” Munipalli added.

In each of the syndromes mentioned, Munipalli detailed how the brain processes sensory input faster, causing the sensory signals to become “amplified and more widespread as more areas of the brain become activated.” 

“This results in the central nervous system becoming sensitized,” she said. “And I suspect this is what is happening with patients who have PASC and demonstrate alcohol sensitivity.”

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Anyone experiencing symptoms of alcohol use disorder should seek help from a doctor, therapist or counselor, experts recommend.

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Video: Why Milder Symptoms Could Make This Ebola Outbreak More Dangerous

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Video: Why Milder Symptoms Could Make This Ebola Outbreak More Dangerous

new video loaded: Why Milder Symptoms Could Make This Ebola Outbreak More Dangerous

Early signs indicate that the species of Ebola behind the current outbreak in the Democratic Republic of Congo may have milder symptoms than past outbreaks. Our global health reporter Apoorva Mandavilli explains why this might actually make it more dangerous.

By Apoorva Mandavilli, Alexandra Ostasiewicz, Nikolay Nikolov, Stephanie Swart, Rafaela Balster and Lauren Pruitt

June 23, 2026

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Want to age better? Researchers say 4-minute routine may help prevent dangerous falls

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Want to age better? Researchers say 4-minute routine may help prevent dangerous falls

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Just four minutes of daily strength exercises can dramatically improve mobility, balance and leg strength in older adults, per new research from the Penn State College of Medicine.

Standard public health guidelines recommend at least 150 minutes of moderate exercise per week. However, the study suggests that fewer than one in five older adults meet the recommended muscle-strengthening guidelines.

The research team designed a home-based program called Functional Activity Strength Training, or FAST-2. They evaluated 97 sedentary participants 65 and older, with an average age of 74.

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Before entering the study, these individuals were averaging just 18 minutes of total physical activity each week.

The older adults were randomly split into two groups, with one group performing the daily exercise routine and the other serving as a control group that received no intervention, according to the study’s press release.

Just four minutes of daily home strength training can significantly improve mobility, balance and leg strength in older adults, according to a Penn State College of Medicine study. (iStock)

Participants performed four basic movements for 30 seconds each, separated by 30-second rest intervals. The entire routine lasted exactly four minutes. The circuit consisted of push-ups, chair stands, two-arm resistance-band rows and stair stepping.

To keep the routine accessible, researchers provided written explanations and simple modifications. For example, participants could perform push-ups against a kitchen counter or wall, or use their hands on their knees for support during chair stands.

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Participants were also given four elastic resistance bands and an adjustable step platform.

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“Exercise is actually really complicated, because you have to decide how many repetitions, how far, how many sets, how much rest and how many times per week,” co-author Smita Dandekar, associate professor of pediatrics at Penn State College of Medicine, said in the press release.

“It’s hard work … so if we can make it short, we’re part [of the] way there.”

The program consisted of four basic movements: push-ups, chair stands, resistance-band rows and stair stepping. (iStock)

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As the participants grew stronger, they were encouraged to progress to higher levels of difficulty, such as transitioning away from modifications or increasing the height of the stepper.

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After 12 weeks, the results suggested that a tiny dose of regular exercise could yield noticeable physical benefits. In a 30-second chair-stand test, the exercise group performed an average of 4.2 more repetitions than the control group.

“These indicators … give you a sense of whether or not you’re going to be able to be active in the future.”

The adults doing the exercises also shaved 2.3 seconds off their time during a test measuring how they could stand up and sit down five times consecutively. Furthermore, they extended their one-legged balance time by an average of 3.6 seconds.

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The researchers emphasized that these specific measurements are critical medical indicators of an older adult’s future health.

By keeping the routine ultra-short, researchers eliminated common barriers like time constraints and exhaustion, resulting in an exceptionally high 81% workout completion rate. (iStock)

“These indicators predict your future ability to go into a nursing home, your future likelihood of falling and of developing difficulty walking,” noted lead author Christopher Sciamanna, professor of medicine and of public health at Penn State College of Medicine, in the press release.

“They give you a sense of whether or not you’re going to be able to be active in the future.”

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While traditional home exercise programs generally see low engagement, the participants in this study successfully completed their workouts on 81% of the tracked days, according to the researchers.

After 12 weeks, exercising seniors gained the ability to complete an average of four more chair-stand repetitions than those who did not exercise. (iStock)

The study had several noted limitations. As it tracked a relatively small sample size of fewer than 100 individuals over a brief 12-week time frame, it is unknown whether these mobility gains can be sustained long-term.

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Additionally, the researchers did not specify the exact dropout rates or detail how the routine might affect seniors who already relied on assistive devices like walkers or canes.

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Because the final trial results reflected a specific group of participants who met the entry criteria, further investigation is required to determine whether the short routine can safely benefit older adults facing more severe physical limitations or cognitive decline.

The study was published in the journal PLOS One.

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Popular mommy blogger dies at 48 two years after devastating cancer diagnosis

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Popular mommy blogger dies at 48 two years after devastating cancer diagnosis

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Jill Smokler, founder of Scary Mommy, has died at age 48 after a battle with glioblastoma, an aggressive form of brain cancer.

The popular “mommy blogger” had been fighting the disease for the past two years, according to an announcement posted on ScaryMommy.com on Monday.

The stay-at-home mother of three launched the blog in 2008 as a place to share the “joys and pitfalls” of parenting, according to the article.

As Scary Mommy expanded from a personal blog into a major parenting brand, Smokler built a following with her honest, often self-deprecating take on motherhood. She went on to speak at blogging conferences, author bestselling books, appear on national television programs and earn three Webby Awards, her biography states.

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“Jill spent her life telling the truth about motherhood — that it could be wonderful and impossible in the very same breath — and in doing so, she gave millions of women permission to stop pretending and feel a little less alone,” her family shared in a statement following her passing.

Jill Smokler, founder of Scary Mommy (pictured in 2018), has died at age 48 after a battle with glioblastoma, an aggressive form of brain cancer. (Lloyd Fox/Baltimore Sun/ZUMA Press Wire / Shutterstock)

“She was funny, fearless, generous and entirely herself. More than anything she built, Jill was proudest of her three children, Lily, Ben and Evan. We are heartbroken to lose her, and endlessly proud of the mark she left on the world.”

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Smokler’s first sign of the disease was in April 2024, when she experienced a sudden seizure. She then underwent surgery to remove a brain tumor, after which she didn’t recognize her own children, she previously shared with Today.

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“I am definitely grateful that I don’t remember the looks on their faces when I didn’t recognize them,” she said. “That must have been gutting.”

Smokler was diagnosed with glioblastoma, the most common malignant primary brain tumor in adults and one of the deadliest forms of brain cancer. There is currently no cure.

About 13.9% of all brain tumors are glioblastomas, according to the American Brain Tumor Association. (iStock)

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Following surgery, the blogger underwent radiation and chemotherapy, during which she was open about her treatment side effects, including fatigue and hair loss. Additional surgeries and clinical trials followed, according to previous interviews.

“Thank you, Jill, for everything. May you rest in peace,” the Scary Mommy post concluded.

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About 13.9% of all brain tumors are glioblastomas, according to the American Brain Tumor Association. More than 12,000 new cases are diagnosed in the U.S. each year.

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Median survival is approximately 12 to 18 months after diagnosis, even with treatment. Only about 5% to 7% of patients survive five years after diagnosis, data shows.

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