Health
Ketamine therapy shown effective in treating severe depression in veterans, study finds
Ketamine could be a viable remedy for veterans struggling with depression, new research has suggested.
The University of Michigan released a study on the effects of ketamine in cases of severe or treatment-resistant depression among veterans.
Half of the study participants experienced significant relief after undergoing six weeks of ketamine therapy, according to a Michigan Medicine press release.
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The study, published in the Journal of Clinical Psychiatry, looked into the data of 215 veterans receiving intravenous ketamine therapy at Veterans Affairs (VA) hospitals.
All the participants had also undergone previous depression treatments without any improvement.
Research from the University of Michigan found that ketamine therapy could be beneficial for veterans with depression. (Julia Rendleman for The Washington Post via Getty Images; iStock)
Nearly half of all patients saw a “meaningful drop” in depression scores after six weeks of infusions, according to the analysis by the University of Michigan and VA Ann Arbor Healthcare System (VAAAHS).
About 25% saw their depression score drop by half within six weeks of treatment, while 15% went into full remission despite the complexity of their mental health status.
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Almost all patients surveyed continued their treatment every few weeks or months.
“Further study is needed to determine optimal infusion frequency and potential for adverse effects with repeated ketamine infusions for depression,” the study findings stated.
Nearly half the participants in a new study saw a “meaningful drop” in depression scores after six weeks of IV ketamine infusions, the study found. (iStock)
In a statement sent to Fox News Digital, VA press secretary Terrence Hayes backed ketamine therapy as an option for veterans.
“VA supports the evidence-based use of ketamine infusions for treatment-resistant depression and severe suicidal ideation,” he said.
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“Many veterans with these mental health conditions are treated with IV ketamine annually – both at VA facilities and by community providers.”
Dr. Justin Gerstner, psychiatrist and chief medical officer at Ellie Mental Health in Minnesota, told Fox News Digital that he thinks these findings on ketamine are “great,” as the VA population is “in need of new, innovative treatments for depression.”
(Gerstner was not involved in the Michigan study.)
A doctor holds a vial of ketamine at the MindPeace Clinic in Richmond, Virginia. (Julia Rendleman for The Washington Post via Getty Images)
“This study shows that this helps some of the hardest-to-treat veterans with depression,” he said.
As more psychedelic-assisted therapies emerge to treat numerous mental health issues, the doctor said ketamine is among the ones that produce results “pretty quickly.”
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Another benefit of ketamine therapy, according to Gerstner, is that it eliminates the need for patients to take medication every day, as with other treatment methods.
Gerstner said he uses ketamine therapy in his own practice, where the response from clients has been “great.”
Carl Montalbino, 67, receives his ketamine treatment while nurse Melissa Dougher checks his vitals on July 5, 2022, at MindPeace Clinic in Richmond, Virginia. (Julia Rendleman for The Washington Post via Getty Images)
“It’s been quite transformative for a lot of our clients,” he told Fox News Digital. “It’s really a rewarding experience to be a part of that.”
Gerstner’s practice usually administers ketamine to clients via IV injection in two- to three-hour sessions, partnered with psychotherapy before and after treatment.
Potential risks and limitations
While ketamine can work as a “really powerful anti-depressant and anti-suicidal drug,” Gerstner said, he warned that it is “not the right answer for everybody or everything.”
“This is a really powerful medication and the way that it’s used can vary quite drastically.”
There are some risks and limitations involved, he said — including the potential for ketamine to be abused.
There isn’t too much regulation surrounding how ketamine treatments are administered, Gerstner noted, since the drug was previously approved for anesthetic use.
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“The field is wide open, and it’s a little bit like the Wild West,” he said. “This is a really powerful medication and the way that it’s used can vary quite drastically.”
Various clinics have seen success with administering the drug in different forms, including oral, IV and injectable, according to Gerstner.
Various clinics have seen success with the drug being administered in different forms, including oral, IV and injectable. (Julia Rendleman for The Washington Post via Getty Images)
For patients with severe treatment-resistant depression, a typical IV regimen is administered every two to three days in a hospital-based outpatient clinic, according to Michigan Medicine and VAAAHS.
“Those things are really all over the map,” Gerstner said. “It’s hard to regulate and there’s some risk in that, but it’s also what we have to do while learning what’s best.”
For veterans who are seeking better treatment, ketamine could be a “really important thing to consider for depression,” said Gerstner
“If they’re suffering with depression and feel like they’re not getting what they need, and they haven’t had a discussion about ketamine, it’s OK to ask [their provider] about it,” he added.
Fox News Digital reached out to the University of Michigan requesting additional comment on the research.
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Health
Diabetes surge among Americans could be driven by ‘healthy’ breakfasts, doctor warns
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Americans consume foods every day that are marketed as “healthy,” when they could be quietly destroying their health, one doctor warns.
Dr. Mark Hyman, physician and co-founder of Function Health in California, says that much of America’s daily diet is filled with unhealthy ingredients.
“The amount of refined starches and sugars that are everywhere is just staggering to me, given what we know about how harmful they are,” he shared in an interview with Fox News Digital. “I don’t think people really understand.”
Hyman, author of the new book “Food Fix Uncensored,” said he’s “astounded” by what people are eating, especially for breakfast.
“People just eat sugar for breakfast,” he said. “They have muffins, they have bagels, they have croissants, they have sugar-sweetened coffees and teas.”
Dr. Mark Hyman is the author of the new book “Food Fix Uncensored.” (Function Health; Little, Brown Spark)
In addition to the traditionally sweet options for breakfast, some cereal brands and breakfast staples have adopted new “protein-packed” menu items and products, following health trends that encourage eating more protein.
“Highly processed food is not food.”
“Now, we’re seeing this halo of protein in certain things,” Hyman said, mentioning that many protein smoothies are “full of sugar.”
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The doctor also noted that some popular cereals are now marketed as having protein in them. “My joke is, if it has a health claim on the label, it’s definitely bad for you,” he said.
Instead of starting the day with a “quick fix” or processed food, Hyman suggests choosing whole sources of protein and fat for breakfast, adding that “if there’s a little carbohydrate in there, it’s fine.”
More products marketed as “high protein” have cropped up on supermarket shelves. (iStock)
For his own breakfast, Hyman said he has a protein shake with whey protein, avocado and frozen berries. Eggs and avocados are also a great protein-and-fat combo option, he added.
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“It’s not that complicated — people need to just think about their breakfast not being dessert,” he said. “No wonder we’re in this cycle of obesity and diabetes. One in three teenage kids now has type 2 diabetes or pre-diabetes. That’s just criminal.”
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Instead of counting calories and being in a caloric deficit as a way to lose weight and stay healthy, Hyman instead suggests focusing on how certain foods make you feel and how they impact your health.
“When you look at the way in which different types of calories affect your biology, you can just choose what you’re eating, and then you don’t have to worry about how much,” he told Fox News Digital.
In addition to the traditionally sweet options for breakfast, some cereal brands and breakfast staples have adopted new “protein-packed” menu items and products. (iStock)
“For example, if you eat a diet that doesn’t cause your insulin to spike — which is low in starch and sugar, higher in protein and fat — you won’t develop those swings in blood sugar, you won’t develop the spikes in insulin, you won’t deposit hungry fat … You will break that cycle.”
People are more likely to “self-regulate when they eat real food” instead of processed foods, which “bypasses the normal mechanisms of satiety, fullness and brain chemistry,” according to Hyman.
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“Ultraprocessed food and junk food or highly processed food is not food,” he said. “It doesn’t support the health and well-being of an organism. It doesn’t do that. It does the opposite.”
Health
Scientists make startling discovery when examining prostate cancer tissue
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Small fragments of plastic were found in the tumors of most prostate cancer patients, according to a new study from NYU Langone Health.
In past studies, microplastics have been found in almost every human organ and in bodily fluids, but their impact on human health still isn’t fully understood.
The researchers analyzed tissue samples from 10 patients with prostate cancer who underwent surgery to remove the entire organ.
Using visuals of both benign samples and tumor samples, as well as specialized equipment, the scientists identified plastic particles in 90% of the tumor samples and 70% of benign tissue samples, according to the study press release.
In past studies, microplastics were found in almost every single human organ along with bodily fluids, even the placenta. (iStock)
The cancerous tissue contained on average more than double the amount of plastic as healthy prostate tissue samples, the study found. This equates to about 40 micrograms of plastic per gram of tissue compared to 16 micrograms.
Researchers avoided contaminating the samples with other plastics by substituting standard tools with those made of aluminum, cotton and other non-plastic material, the release noted.
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The scientists say this is the first direct evidence linking microplastics to prostate cancer.
“By uncovering yet another potential health concern posed by plastic, our findings highlight the need for stricter regulatory measures to limit the public’s exposure to these substances, which are everywhere in the environment,” said senior study author Vittorio Albergamo, assistant professor in the department of pediatrics at NYU Grossman School of Medicine, in the release.
Using visuals of both benign samples and tumor samples, as well as specialized equipment, the scientists identified plastic particles in 90% of the tumor samples and 70% of benign tissue samples. (iStock)
The study findings were presented during the American Society of Clinical Oncology’s Genitourinary Cancers Symposium in San Francisco on Feb. 26.
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“What is most striking is not that microplastics were detected, but that they were found embedded within tumor tissue itself,” Dr. David Sidransky, oncologist and medical advisor at SpotitEarly, a startup that offers an at-home breath-based test to detect early-stage cancer, told Fox News Digital.
“While complete avoidance is unrealistic, people can take practical steps to reduce exposure.”
“We already know microplastics are present in water, air, blood and even placental tissue. Their detection in prostate tumors suggests systemic distribution and long-term bioaccumulation,” added Maryland-based Sidransky, who was not involved in the study.
Study limitations
Albergamo cautioned that a larger sample is needed to confirm the findings. Additionally, Sidransky noted that the presence of microplastics alone does not prove they cause cancer.
“Tumors can act as ‘biologic sinks,’ meaning they may accumulate circulating particles simply because of altered vasculature and permeability,” he said.
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A key unanswered question, according to the doctor, is whether microplastics are biologically active in ways that “promote DNA damage, immune modulation or chronic inflammation within the prostate.”
About one in eight men in the U.S. will be diagnosed with prostate cancer at some point in their lifetime, according to the Centers for Disease Control and Prevention.
The most actionable step men can take is appropriate screening and early detection, according to doctors. (iStock)
For those concerned about microplastics, Sidransky offered some insights.
“I believe the appropriate response is curiosity, not panic, and a commitment to understand more,” he said.
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“While complete avoidance is unrealistic, people can take practical steps to reduce exposure, such as minimizing heating food in plastic containers, reducing bottled water consumption when possible, and favoring glass or stainless steel alternatives.”
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The most actionable step men can take, however, is getting appropriate screenings to help ensure early detection, according to the doctor. Screening discussions should be individualized based on age, family history and other risk factors.
Health
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