Health
H.H.S. Scraps Studies of Vaccines and Treatments for Future Pandemics
The Trump administration has canceled funding for dozens of studies seeking new vaccines and treatments for Covid-19 and other pathogens that may cause future pandemics.
The government’s rationale is that the Covid pandemic has ended, which “provides cause to terminate Covid-related grant funds,” according to an internal N.I.H. document viewed by The New York Times.
But the research was not just about Covid. Nine of the terminated awards funded centers conducting research on antiviral drugs to combat so-called priority pathogens that could give rise to entirely new pandemics.
“This includes the antiviral projects designed to cover a wide range of families that could cause outbreaks or pandemics,” said one senior N.I.H. official who spoke on condition of anonymity for fear of retaliation.
The vaccine research also was not focused on Covid, but rather on other coronaviruses that one day might jump from animals to humans.
Describing all the research as Covid-related is “a complete inaccuracy and simply a way to defund infectious disease research,” the official said. Robert F. Kennedy Jr., the health secretary, has said that the N.I.H. is too focused on infectious diseases, the official noted.
The funding halts were first reported by Science and Nature. The cancellations stunned scientists who had depended on the government’s support.
“The idea that we don’t need further research to learn how to treat health problems caused by coronaviruses and prevent future pandemics because ‘Covid-19 is over’ is absurd,” said Pamela Bjorkman, a structural biologist at Caltech who had been studying new vaccines.
The goal of the projects was to have vaccines and drugs ready if a new pandemic hit, rather than spending precious months developing them from scratch.
“In the last pandemic, we really were caught with our pants down,” said Paul Bieniasz, a virologist at Rockefeller University who was collaborating with Dr. Bjorkman.
“And if we don’t learn that lesson and prepare better for the next pandemic, we are unlikely to do better than we did last time.”
Dr. Bieniasz, Dr. Bjorkman and their colleagues were developing a vaccine that might protect against a wide range of coronavirus species.
The researchers discovered new strategies to coax the immune system to learn how to recognize molecular features common to more than just one type of virus. Results from animal experiments were promising.
But now, with their funds abruptly cut, the scientists said they doubted they could build on those results. Dr. Bieniasz said that the termination had left him “angry, disappointed, frustrated.”
Other scientists had been working on antiviral treatments, part of a program started in 2021.
With $577 million in support from the N.I.H., a nationwide network of labs had been studying how viruses replicate, and then searching for drugs that could block them.
The researchers focused on viral families that include some of the most worrisome pathogens known, such as Ebola and Nipah virus. Scientists had discovered a number of promising molecules and were advancing toward clinical trials.
Reuben Harris, a molecular virologist at UT Health San Antonio, said that the promising compounds uncovered by the program included an antiviral drug that stops Ebola and related viruses from entering cells.
“It could be deployed to help a lot of people fast,” Dr. Harris said.
It looked as if some compounds might work against a number of virus families. “It’s some of the most exciting science I’ve seen in my career,” said Nevan Krogan, a systems biologist at the University of California, San Francisco.
On Wednesday morning, Dr. Krogan and dozens of his colleagues gathered in a campus meeting room to review those results. And they also discussed what, if anything, they could do now.
“One student asked me, ‘Well, I have an experiment booked on this microscope tomorrow — can I do it?’” Dr. Krogan said. “And I’m like, ‘Well, I don’t know.’”
Dr. Harris said that, without ongoing support, the promising drugs he and others had found would not move into clinical trials. “It’s tragic — I don’t have too many words to describe that right now,” he said.
In 2023, Mr. Kennedy said that he wanted to take “a break” from infectious disease research to focus instead on chronic disease.
Jason McLellan, a virologist at the University of Texas at Austin who worked on the antiviral program, saw the cancellations of pandemic research as following through on that promise.
Dr. McLellan, whose earlier research was fundamental to the creation of Covid vaccines in 2020, said this week’s cuts made him wonder if he could continue studying pandemics in the United States.
“We’ve had conversations and are beginning to put plans into motion to gather more information,” he said, referring to the possibility of moving abroad.
“My lab is a structural virology lab that focuses on structure-based vaccine design,” he added. “If the focus is on chronic diseases, that doesn’t leave much funding for us.”
Health
Diabetes surge among Americans could be driven by ‘healthy’ breakfasts, doctor warns
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Americans consume foods every day that are marketed as “healthy,” when they could be quietly destroying their health, one doctor warns.
Dr. Mark Hyman, physician and co-founder of Function Health in California, says that much of America’s daily diet is filled with unhealthy ingredients.
“The amount of refined starches and sugars that are everywhere is just staggering to me, given what we know about how harmful they are,” he shared in an interview with Fox News Digital. “I don’t think people really understand.”
Hyman, author of the new book “Food Fix Uncensored,” said he’s “astounded” by what people are eating, especially for breakfast.
“People just eat sugar for breakfast,” he said. “They have muffins, they have bagels, they have croissants, they have sugar-sweetened coffees and teas.”
Dr. Mark Hyman is the author of the new book “Food Fix Uncensored.” (Function Health; Little, Brown Spark)
In addition to the traditionally sweet options for breakfast, some cereal brands and breakfast staples have adopted new “protein-packed” menu items and products, following health trends that encourage eating more protein.
“Highly processed food is not food.”
“Now, we’re seeing this halo of protein in certain things,” Hyman said, mentioning that many protein smoothies are “full of sugar.”
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The doctor also noted that some popular cereals are now marketed as having protein in them. “My joke is, if it has a health claim on the label, it’s definitely bad for you,” he said.
Instead of starting the day with a “quick fix” or processed food, Hyman suggests choosing whole sources of protein and fat for breakfast, adding that “if there’s a little carbohydrate in there, it’s fine.”
More products marketed as “high protein” have cropped up on supermarket shelves. (iStock)
For his own breakfast, Hyman said he has a protein shake with whey protein, avocado and frozen berries. Eggs and avocados are also a great protein-and-fat combo option, he added.
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“It’s not that complicated — people need to just think about their breakfast not being dessert,” he said. “No wonder we’re in this cycle of obesity and diabetes. One in three teenage kids now has type 2 diabetes or pre-diabetes. That’s just criminal.”
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Instead of counting calories and being in a caloric deficit as a way to lose weight and stay healthy, Hyman instead suggests focusing on how certain foods make you feel and how they impact your health.
“When you look at the way in which different types of calories affect your biology, you can just choose what you’re eating, and then you don’t have to worry about how much,” he told Fox News Digital.
In addition to the traditionally sweet options for breakfast, some cereal brands and breakfast staples have adopted new “protein-packed” menu items and products. (iStock)
“For example, if you eat a diet that doesn’t cause your insulin to spike — which is low in starch and sugar, higher in protein and fat — you won’t develop those swings in blood sugar, you won’t develop the spikes in insulin, you won’t deposit hungry fat … You will break that cycle.”
People are more likely to “self-regulate when they eat real food” instead of processed foods, which “bypasses the normal mechanisms of satiety, fullness and brain chemistry,” according to Hyman.
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“Ultraprocessed food and junk food or highly processed food is not food,” he said. “It doesn’t support the health and well-being of an organism. It doesn’t do that. It does the opposite.”
Health
Scientists make startling discovery when examining prostate cancer tissue
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Small fragments of plastic were found in the tumors of most prostate cancer patients, according to a new study from NYU Langone Health.
In past studies, microplastics have been found in almost every human organ and in bodily fluids, but their impact on human health still isn’t fully understood.
The researchers analyzed tissue samples from 10 patients with prostate cancer who underwent surgery to remove the entire organ.
Using visuals of both benign samples and tumor samples, as well as specialized equipment, the scientists identified plastic particles in 90% of the tumor samples and 70% of benign tissue samples, according to the study press release.
In past studies, microplastics were found in almost every single human organ along with bodily fluids, even the placenta. (iStock)
The cancerous tissue contained on average more than double the amount of plastic as healthy prostate tissue samples, the study found. This equates to about 40 micrograms of plastic per gram of tissue compared to 16 micrograms.
Researchers avoided contaminating the samples with other plastics by substituting standard tools with those made of aluminum, cotton and other non-plastic material, the release noted.
NIGHTLY BATHROOM HABIT WAS MISSED SIGN OF COMMON MEN’S CANCER: ‘I DIDN’T KNOW’
The scientists say this is the first direct evidence linking microplastics to prostate cancer.
“By uncovering yet another potential health concern posed by plastic, our findings highlight the need for stricter regulatory measures to limit the public’s exposure to these substances, which are everywhere in the environment,” said senior study author Vittorio Albergamo, assistant professor in the department of pediatrics at NYU Grossman School of Medicine, in the release.
Using visuals of both benign samples and tumor samples, as well as specialized equipment, the scientists identified plastic particles in 90% of the tumor samples and 70% of benign tissue samples. (iStock)
The study findings were presented during the American Society of Clinical Oncology’s Genitourinary Cancers Symposium in San Francisco on Feb. 26.
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“What is most striking is not that microplastics were detected, but that they were found embedded within tumor tissue itself,” Dr. David Sidransky, oncologist and medical advisor at SpotitEarly, a startup that offers an at-home breath-based test to detect early-stage cancer, told Fox News Digital.
“While complete avoidance is unrealistic, people can take practical steps to reduce exposure.”
“We already know microplastics are present in water, air, blood and even placental tissue. Their detection in prostate tumors suggests systemic distribution and long-term bioaccumulation,” added Maryland-based Sidransky, who was not involved in the study.
Study limitations
Albergamo cautioned that a larger sample is needed to confirm the findings. Additionally, Sidransky noted that the presence of microplastics alone does not prove they cause cancer.
“Tumors can act as ‘biologic sinks,’ meaning they may accumulate circulating particles simply because of altered vasculature and permeability,” he said.
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A key unanswered question, according to the doctor, is whether microplastics are biologically active in ways that “promote DNA damage, immune modulation or chronic inflammation within the prostate.”
About one in eight men in the U.S. will be diagnosed with prostate cancer at some point in their lifetime, according to the Centers for Disease Control and Prevention.
The most actionable step men can take is appropriate screening and early detection, according to doctors. (iStock)
For those concerned about microplastics, Sidransky offered some insights.
“I believe the appropriate response is curiosity, not panic, and a commitment to understand more,” he said.
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“While complete avoidance is unrealistic, people can take practical steps to reduce exposure, such as minimizing heating food in plastic containers, reducing bottled water consumption when possible, and favoring glass or stainless steel alternatives.”
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The most actionable step men can take, however, is getting appropriate screenings to help ensure early detection, according to the doctor. Screening discussions should be individualized based on age, family history and other risk factors.
Health
How a Vegan Diet Can Help You Lose Weight 8X Faster
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